首页 > 最新文献

International Journal of Pharmacometrics and Integrated Biosciences最新文献

英文 中文
Quantitative Ethnobotany of Medicinal Plants Used by Indigenous Community in the Munnar Forest Division, Kerala, India 印度喀拉拉邦慕那尔森林区土著社区药用植物的数量民族植物学
Pub Date : 2021-06-14 DOI: 10.26452/ijpib.v6i2.1448
Venkatesan K., Murugeswaran R., Mokhtar Alam, Ram Pradap Meena, Pawan Kumar, Mohamed Aslam, Zaheer Ahmed N.
The quantitative ethnobotany deals with the computation of the importance of the plants and vegetation to people. It helps in quantification of qualitative data in the biological and social science. The various quantitative tools in ethnobotany help in the calculation of plant taxon. Ethnobotanical approach provide data which is agreeable to the hypothesis-testing, subsequent statistical validation and comparative analysis. The traditional source of medicinal plants is an important way for daily curative uses in the rural area throughout Kerala. Moreover, among the plant studied habit wise analyzed they are 12 herbs, 13 shrubs, 12 trees and each one of climbing shrub, twining shrub, prostrate shrub, climber. The status of plants are also analyzed and recorded as 26 are common, 14 are rare, 5 are common & Cultivated and 2 are sporadic are described under this study. In this communication, the informations got from the rural inhabitant were compared with the already existing literature. The medicinal plants used by people are arranged alphabetically followed by Botanical name, Family name, Voucher specimen number, Local name, Unani name, Part used, Mode of preparation and Disease cured are discussed. The data were collected randomly from tribal and traditional healers of 85 informants the data were statistically analyzed by using suitable statistical tools such as Use Value (UV), Informant Consensus Factor (ICF), Fidelity Value (FL) and various ranking methods.
定量民族植物学研究的是计算植物和植被对人类的重要性。它有助于生物科学和社会科学中定性数据的量化。民族植物学中的各种定量工具有助于植物分类群的计算。民族植物学方法提供了符合假设检验、后续统计验证和比较分析的数据。药用植物的传统来源是喀拉拉邦农村地区日常治疗的重要途径。其中,草本植物12种,灌木13种,乔木12种,攀缘灌木、缠绕灌木、匍匐灌木、攀缘灌木各1种。对植物的分布状况进行了分析和记录,其中常见植物26种,稀有植物14种,常见栽培植物5种,散发植物2种。在这次交流中,从农村居民那里获得的信息与已有的文献进行了比较。按植物名、族名、凭证标本号、地名、乌拉尼名、使用部位、制备方式、治疗疾病等顺序排列。随机从85名被调查者的部落和传统治疗师中收集数据,采用使用价值(UV)、被调查者共识因子(ICF)、忠诚值(FL)等合适的统计工具和各种排序方法对数据进行统计分析。
{"title":"Quantitative Ethnobotany of Medicinal Plants Used by Indigenous Community in the Munnar Forest Division, Kerala, India","authors":"Venkatesan K., Murugeswaran R., Mokhtar Alam, Ram Pradap Meena, Pawan Kumar, Mohamed Aslam, Zaheer Ahmed N.","doi":"10.26452/ijpib.v6i2.1448","DOIUrl":"https://doi.org/10.26452/ijpib.v6i2.1448","url":null,"abstract":"The quantitative ethnobotany deals with the computation of the importance of the plants and vegetation to people. It helps in quantification of qualitative data in the biological and social science. The various quantitative tools in ethnobotany help in the calculation of plant taxon. Ethnobotanical approach provide data which is agreeable to the hypothesis-testing, subsequent statistical validation and comparative analysis. The traditional source of medicinal plants is an important way for daily curative uses in the rural area throughout Kerala. Moreover, among the plant studied habit wise analyzed they are 12 herbs, 13 shrubs, 12 trees and each one of climbing shrub, twining shrub, prostrate shrub, climber. The status of plants are also analyzed and recorded as 26 are common, 14 are rare, 5 are common & Cultivated and 2 are sporadic are described under this study. In this communication, the informations got from the rural inhabitant were compared with the already existing literature. The medicinal plants used by people are arranged alphabetically followed by Botanical name, Family name, Voucher specimen number, Local name, Unani name, Part used, Mode of preparation and Disease cured are discussed. The data were collected randomly from tribal and traditional healers of 85 informants the data were statistically analyzed by using suitable statistical tools such as Use Value (UV), Informant Consensus Factor (ICF), Fidelity Value (FL) and various ranking methods.","PeriodicalId":170261,"journal":{"name":"International Journal of Pharmacometrics and Integrated Biosciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128922766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Work related injuries sustained by emergency medical technicians and paramedics in Saudi Arabia 沙特阿拉伯紧急医疗技术人员和护理人员因工受伤
Pub Date : 2021-03-27 DOI: 10.26452/IJPIB.V6I1.1408
Tarek M. Esmael, Samiha Fawzy, Hany Hosny, O. Rashed, Anas Alnasser, T. A. Anazi, Arulanantham Zechariah Jebakumar
Emergency medical technicians (EMTs) and paramedics take immediate care of patients who are injured or unhealthy and ensure their transportation to or from the hospital. Almost 10% of all European Union employees work in health and social care systems, and a considerable number of them work in hospitals. The same is the case in Saudi Arabia, where the health care system is well developed and vibrant. With such a large workforce working in an environment where they can face accidents and injuries, accidents do happen.  According to the International Labor Organization, there are 270 million occupational accidents causing 2 million deaths annually.  The study was conducted at King Fahd Military Complex, Dhahran and Red Crescent. The study was aimed to identify the nature, frequency and causes of work-related injuries among paramedical staff. The present is among the largest studies of WRIs in EMTs in Saudi Arabia. In this study, we found a very high rate of verbal and physical violence against healthcare personnel. Physical violence negatively affects levels of satisfaction in workers. Studies indicate that exposure to both chronic and critical incident stressors increases the risk of EMS personnel developing post-traumatic stress reactions. The risk of WRIs to paramedics and EMTs is obviously high. The most common injuries were verbal/ physical violence, needle stick injuries and motor vehicle accidents. The most common cause for these WRIs was carelessness on part of EMTs.
紧急医疗技术人员(emt)和护理人员立即照顾受伤或不健康的病人,并确保他们往返医院。近10%的欧盟雇员在卫生和社会保健系统工作,其中相当多的人在医院工作。沙特阿拉伯的情况也是如此,那里的医疗保健系统非常发达,充满活力。如此庞大的劳动力在一个他们可能面临事故和伤害的环境中工作,事故确实发生了。据国际劳工组织统计,每年发生2.7亿起职业事故,造成200万人死亡。这项研究是在达赫兰和红新月会法赫德国王军事综合体进行的。这项研究的目的是查明医务辅助人员工伤的性质、频率和原因。本研究是沙特阿拉伯emt中wri最大的研究之一。在这项研究中,我们发现针对医护人员的言语和身体暴力发生率非常高。身体暴力会对员工的满意度产生负面影响。研究表明,暴露于慢性和严重事件应激源会增加EMS人员发生创伤后应激反应的风险。wri对护理人员和急救人员的风险明显很高。最常见的伤害是语言/身体暴力、针扎伤和机动车事故。这些wri最常见的原因是部分急救医生的粗心大意。
{"title":"Work related injuries sustained by emergency medical technicians and paramedics in Saudi Arabia","authors":"Tarek M. Esmael, Samiha Fawzy, Hany Hosny, O. Rashed, Anas Alnasser, T. A. Anazi, Arulanantham Zechariah Jebakumar","doi":"10.26452/IJPIB.V6I1.1408","DOIUrl":"https://doi.org/10.26452/IJPIB.V6I1.1408","url":null,"abstract":"Emergency medical technicians (EMTs) and paramedics take immediate care of patients who are injured or unhealthy and ensure their transportation to or from the hospital. Almost 10% of all European Union employees work in health and social care systems, and a considerable number of them work in hospitals. The same is the case in Saudi Arabia, where the health care system is well developed and vibrant. With such a large workforce working in an environment where they can face accidents and injuries, accidents do happen.  According to the International Labor Organization, there are 270 million occupational accidents causing 2 million deaths annually.  The study was conducted at King Fahd Military Complex, Dhahran and Red Crescent. The study was aimed to identify the nature, frequency and causes of work-related injuries among paramedical staff. The present is among the largest studies of WRIs in EMTs in Saudi Arabia. In this study, we found a very high rate of verbal and physical violence against healthcare personnel. Physical violence negatively affects levels of satisfaction in workers. Studies indicate that exposure to both chronic and critical incident stressors increases the risk of EMS personnel developing post-traumatic stress reactions. The risk of WRIs to paramedics and EMTs is obviously high. The most common injuries were verbal/ physical violence, needle stick injuries and motor vehicle accidents. The most common cause for these WRIs was carelessness on part of EMTs.","PeriodicalId":170261,"journal":{"name":"International Journal of Pharmacometrics and Integrated Biosciences","volume":"66 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132790945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of anti-inflammatory activity of various species of lamiaceae 不同兰科植物抗炎活性的比较
Pub Date : 2021-03-11 DOI: 10.26452/IJPIB.V6I1.1405
N. Deepa, K. Madhivadhani, M. Hari, N. Prakash, S. Lohith, C. Prabakaran
The process of inflammation is often triggered by the stimulus from outside sources that usally cause harm to human skin and tissues. It is a response of the body that protects itself from external agents but when it is excess and built up in the body it causes some worsening symptoms. Synthetic drugs usually cause side effects and adverse effects. Herbs are normally known to combat inflammations and fight free radicals. The antioxidants present in the herbs causes the preventive action of the oxidation and causes lowering of the inflammation. There were also investigations performed on the plant to prove the above activities. Among all the plants that are available in nature lamiaceae members, plants like Molucella laevis, Nepeta cataria, Vitex agnus, Origanum dictamnus and Mentha piperata were considered as major medicinal plants with a lot of medical applications. 5 members of lamiaceae were selected to study and compare the anti-inflammatory activity and the data suggests all the plants have better activity and out of all the Mentha extract showed a significantly better activity compared to the standard drug.
炎症的过程通常是由外界刺激引起的,通常会对人体皮肤和组织造成伤害。它是身体保护自己免受外界影响的一种反应,但当它过量并在体内积聚时,它会导致一些恶化的症状。合成药物通常会产生副作用和不良反应。草药通常被认为可以对抗炎症和自由基。存在于草药中的抗氧化剂可以预防氧化,降低炎症。此外,当局亦对该工厂进行调查,以证实上述活动。在自然界的片科植物中,Molucella laevis、Nepeta cataria、Vitex agnus、Origanum dictamnus和Mentha piperata等植物被认为是主要的药用植物,具有广泛的医学应用。选取5种薄荷科植物对其抗炎活性进行研究比较,结果表明,所有植物的抗炎活性都较好,其中薄荷提取物的抗炎活性明显优于标准药物。
{"title":"Comparison of anti-inflammatory activity of various species of lamiaceae","authors":"N. Deepa, K. Madhivadhani, M. Hari, N. Prakash, S. Lohith, C. Prabakaran","doi":"10.26452/IJPIB.V6I1.1405","DOIUrl":"https://doi.org/10.26452/IJPIB.V6I1.1405","url":null,"abstract":"The process of inflammation is often triggered by the stimulus from outside sources that usally cause harm to human skin and tissues. It is a response of the body that protects itself from external agents but when it is excess and built up in the body it causes some worsening symptoms. Synthetic drugs usually cause side effects and adverse effects. Herbs are normally known to combat inflammations and fight free radicals. The antioxidants present in the herbs causes the preventive action of the oxidation and causes lowering of the inflammation. There were also investigations performed on the plant to prove the above activities. Among all the plants that are available in nature lamiaceae members, plants like Molucella laevis, Nepeta cataria, Vitex agnus, Origanum dictamnus and Mentha piperata were considered as major medicinal plants with a lot of medical applications. 5 members of lamiaceae were selected to study and compare the anti-inflammatory activity and the data suggests all the plants have better activity and out of all the Mentha extract showed a significantly better activity compared to the standard drug.","PeriodicalId":170261,"journal":{"name":"International Journal of Pharmacometrics and Integrated Biosciences","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116722031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Phytochemical and pharmacological investigations of Pseudarthria viscida (L.) Wight & Arnott 粘胶假关节炎的植物化学和药理研究怀特&阿诺特公司
Pub Date : 2020-07-06 DOI: 10.26452/ijpib.v5i2.1217
K. Nithyakalyani
Pseudarthria viscida L. Wight & Arnott belongs to family Leguminosae commonly called as Salaparni is an essential component of potent Ayurvedic formulations. It has been screened for antioxidant, cytotoxic, antidiabetic & anti-diarrhoeal activity. Currently, there is no enough scientific evidence or literary resources on the anti-inflammatory & antipyretic activity of this plant. Therefore, this study was aimed at exploring P.viscida for its therapeutic potentials as anti-inflammatory & antipyretic agent. A research was conducted to evaluate the anti-inflammatory property ( inflammation-induced to rat paw oedema by carrageenan & cotton pellet granuloma) & antipyretic (Pyrexia induced by brewer’s yeast) activities of petroleum ether extract of Pseudarthria viscida (PEPV) stems & roots in albino rats. Pre-treatment of the animals with the plant extract (100 & 200 mg/kg, p.o.) has prevented the inflammation produced evident by the change in volume of paw oedema which is proportional to the dose. A maximum effect was seen at 200 mg/kg, which was competent to Indomethacin (10 mg/kg, i.p). The antipyretic effect of PEPV (100 & 200 mg/kg, p.o.), measured as percentage lowering in body heat was compared with st&ard, Paracetamol (150 mg/kg, p.o.). The anti-inflammatory & antipyretic activities showed dose-related response at 100 mg/kg & 200 mg/kg, when compared to the st&ard. This current research investigated & advocates the anti pyretic property & anti-inflammatory potency of Pseudarthria viscida, and it supports the application of the plant in medicine as per ethnopharmacology. 
假假木犀属豆科,通常被称为萨拉帕尼,是有效的阿育吠陀配方的重要组成部分。它已被筛选为抗氧化,细胞毒性,抗糖尿病和抗腹泻活性。目前,关于该植物的抗炎解热作用还没有足够的科学依据和文献资源。因此,本研究的目的是探索鼠舌草作为抗炎解热药物的治疗潜力。本研究评价了石油醚提取物(PEPV)对白化大鼠的抗炎作用(角叉胶和棉花颗粒肉芽肿引起的大鼠足部水肿)和解热作用(啤酒酵母引起的发热)。用植物提取物(100和200 mg/kg, p.o.)对动物进行预处理,可以防止炎症产生,足踝水肿体积的变化与剂量成正比。200 mg/kg时效果最大,与吲哚美辛(10 mg/kg,口服)相当。将PEPV(100和200 mg/kg, p.o.)的解热作用与标准的扑热息痛(150 mg/kg, p.o.)进行比较。在100mg /kg和200mg /kg时,与标准对照,抗炎和解热活性呈剂量相关。本研究从民族药理学角度考察和倡导了假膝草的解热和抗炎作用,支持了该植物在医学上的应用。
{"title":"Phytochemical and pharmacological investigations of Pseudarthria viscida (L.) Wight & Arnott","authors":"K. Nithyakalyani","doi":"10.26452/ijpib.v5i2.1217","DOIUrl":"https://doi.org/10.26452/ijpib.v5i2.1217","url":null,"abstract":"Pseudarthria viscida L. Wight & Arnott belongs to family Leguminosae commonly called as Salaparni is an essential component of potent Ayurvedic formulations. It has been screened for antioxidant, cytotoxic, antidiabetic & anti-diarrhoeal activity. Currently, there is no enough scientific evidence or literary resources on the anti-inflammatory & antipyretic activity of this plant. Therefore, this study was aimed at exploring P.viscida for its therapeutic potentials as anti-inflammatory & antipyretic agent. A research was conducted to evaluate the anti-inflammatory property ( inflammation-induced to rat paw oedema by carrageenan & cotton pellet granuloma) & antipyretic (Pyrexia induced by brewer’s yeast) activities of petroleum ether extract of Pseudarthria viscida (PEPV) stems & roots in albino rats. Pre-treatment of the animals with the plant extract (100 & 200 mg/kg, p.o.) has prevented the inflammation produced evident by the change in volume of paw oedema which is proportional to the dose. A maximum effect was seen at 200 mg/kg, which was competent to Indomethacin (10 mg/kg, i.p). The antipyretic effect of PEPV (100 & 200 mg/kg, p.o.), measured as percentage lowering in body heat was compared with st&ard, Paracetamol (150 mg/kg, p.o.). The anti-inflammatory & antipyretic activities showed dose-related response at 100 mg/kg & 200 mg/kg, when compared to the st&ard. This current research investigated & advocates the anti pyretic property & anti-inflammatory potency of Pseudarthria viscida, and it supports the application of the plant in medicine as per ethnopharmacology. ","PeriodicalId":170261,"journal":{"name":"International Journal of Pharmacometrics and Integrated Biosciences","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134338245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute and chronic toxicity studies on Polygonum glabrum in experimental animals 黄精对实验动物的急性和慢性毒性研究
Pub Date : 2020-07-06 DOI: 10.26452/ijpib.v3i1.1216
A. Saravanakumar, R. Gandhimathi
Polygonum glabrum is being used in traditional and folklore medicine to treat pneumonia and jaundice. Plant roots are used in ayurvedic preparations to treat fever and colic. The leaves are used as diuretic agents and process vermifuge action. Plant decoction is also used in the treatment of Rheumatism. Besides having many uses and folklore claims, herbal medicines are to be thoroughly investigated for their toxicity also. Therefore this work is being carried out to examine the toxicity of the drug and established dose is safe to use in the clinical stage. The current research studied the acute and chronic toxicity of Polygonum glabrum root extract in rats. It is proved that there was no change in any parameter tested both in acute and chronic toxicity, which means the extract is safe and non-toxic at the dose of 2g/kg also.
黄精在传统和民间医学中用于治疗肺炎和黄疸。植物根在阿育吠陀制剂中用于治疗发烧和绞痛。叶子被用作利尿剂和处理寄生虫的作用。植物汤剂也用于治疗风湿病。除了有许多用途和民间传说,草药也要彻底调查其毒性。因此,这项工作正在进行,以检查药物的毒性和确定的剂量是安全的,可以在临床阶段使用。本研究研究了黄精提取物对大鼠的急性和慢性毒性。在急性和慢性毒性试验中,各项参数均无变化,说明提取物在2g/kg剂量下也是安全无毒的。
{"title":"Acute and chronic toxicity studies on Polygonum glabrum in experimental animals","authors":"A. Saravanakumar, R. Gandhimathi","doi":"10.26452/ijpib.v3i1.1216","DOIUrl":"https://doi.org/10.26452/ijpib.v3i1.1216","url":null,"abstract":"Polygonum glabrum is being used in traditional and folklore medicine to treat pneumonia and jaundice. Plant roots are used in ayurvedic preparations to treat fever and colic. The leaves are used as diuretic agents and process vermifuge action. Plant decoction is also used in the treatment of Rheumatism. Besides having many uses and folklore claims, herbal medicines are to be thoroughly investigated for their toxicity also. Therefore this work is being carried out to examine the toxicity of the drug and established dose is safe to use in the clinical stage. The current research studied the acute and chronic toxicity of Polygonum glabrum root extract in rats. It is proved that there was no change in any parameter tested both in acute and chronic toxicity, which means the extract is safe and non-toxic at the dose of 2g/kg also.","PeriodicalId":170261,"journal":{"name":"International Journal of Pharmacometrics and Integrated Biosciences","volume":"237 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116612183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Phytochemistry, pharmacognosy and pharmacological profile of Abutilon indicum 阿布蒂隆植物化学、生药学及药理研究概况
Pub Date : 2020-07-01 DOI: 10.26452/ijpib.v5i1.1191
R. Jubilee, J. Kaviarasu, I. Kishore, S. Keerthana, N. Karthikayan, S. Karthi
Abutilon indicum belongs to the family Malvaceae is known as Indian mallow commonly. The plant was traditionally claimed to possess many medicinal properties and was used in folklore and traditional system s of medicine like Ayurveda. It contains various chemical constituents like flavonoids, phenols, sterols, tannins etc. and was scientifically investigated for many activities like an immune stimulant, dieresis, anti-epileptic, anti-ulcer and anti-parasitic activities. This article reviews the research work that was performed on the plant to publish its phytochemistry, Pharmacognosy and Pharmacological profile of the plant.
锦葵属锦葵科,俗称印度锦葵。传统上,这种植物被认为具有许多药用特性,并被用于民间传说和传统医学体系,如阿育吠陀。它含有多种化学成分,如黄酮类、酚类、甾醇、单宁等,并被科学研究为免疫兴奋剂、利尿、抗癫痫、抗溃疡和抗寄生虫等多种活性。本文综述了近年来对该植物的研究工作,并对其植物化学、生药学和药理特征进行了综述。
{"title":"Phytochemistry, pharmacognosy and pharmacological profile of Abutilon indicum","authors":"R. Jubilee, J. Kaviarasu, I. Kishore, S. Keerthana, N. Karthikayan, S. Karthi","doi":"10.26452/ijpib.v5i1.1191","DOIUrl":"https://doi.org/10.26452/ijpib.v5i1.1191","url":null,"abstract":"Abutilon indicum belongs to the family Malvaceae is known as Indian mallow commonly. The plant was traditionally claimed to possess many medicinal properties and was used in folklore and traditional system s of medicine like Ayurveda. It contains various chemical constituents like flavonoids, phenols, sterols, tannins etc. and was scientifically investigated for many activities like an immune stimulant, dieresis, anti-epileptic, anti-ulcer and anti-parasitic activities. This article reviews the research work that was performed on the plant to publish its phytochemistry, Pharmacognosy and Pharmacological profile of the plant.","PeriodicalId":170261,"journal":{"name":"International Journal of Pharmacometrics and Integrated Biosciences","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124909927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Concepts on Risk Factors Among Patients with Ischemic Stroke 缺血性脑卒中患者危险因素的新概念
Pub Date : 2018-12-12 DOI: 10.26452/ijpib.v3i2.1386
Someswar Deb, Thejaswini Karanth, Pranathi R, Ajoy Krishnamurthy
Stroke remains a chief public fitness hassle in growing international locations. Routine investigation performed to pick out Stroke is imaging, that is luxurious and no longer easy. So we want an ordinary simple take a look at to predict stroke. To have a look at the association between platelet indices, platelet matter and Ischemic Thrombotic stroke. Platelets are small discoid cell factors which can be heterogeneous with admire to size, density, age and metabolic characteristic. The ordinary person human has a platelet be counted among 1—five-four lakhs/mm3. Platelet indices or platelet quantity parameters mainly include Mean Platelet Volume (MPV), Platelet Distribution Width (PDW) and Plateletcrit (PCT). Automated mobile counters have made the platelet matter and platelet volume indices - MPV, PDW and PLCR mechanically to be had in most scientific laboratories. The MPV shows the average length of the platelets and its ordinary extent is 7.4 -10.4fl. According to current research, large platelets are enzymatically and metabolically extra active and have better thrombotic potential compared with smaller ones. Hence individuals with high MPV are said to be at danger for thrombotic activities. The PDW is a measure of platelet anisocytosis. The PCT is the ratio of the volume of platelet cells to the entire amount of blood.  Platelets and their interest have a Svital role inside the pathogenesis of coronary heart disorder. Some research has proven that decreases in platelet are counted can be a characteristic of the prothrombotic state in coronary heart ailment. This can be a result of platelet consumption in the acute segment of clot formation and next thrombosis.
在越来越多的国家,中风仍然是公共健身的一大难题。常规的检查是影像学检查,这是奢侈的,不再容易。所以我们想要一个普通的简单的看一下预测中风。探讨血小板指数、血小板物质与缺血性血栓性脑卒中的关系。血小板是一种小的盘状细胞因子,其大小、密度、年龄和代谢特征各异。普通人人类有一个血小板在1 - 54万/mm3之间。血小板指标或血小板数量参数主要包括平均血小板体积(MPV)、血小板分布宽度(PDW)和血小板电积(PCT)。自动移动计数器使血小板物质和血小板体积指标MPV、PDW和PLCR机械地成为大多数科学实验室的必备指标。MPV显示血小板平均长度,其正常范围为7.4 -10.4fl。根据目前的研究,大血小板在酶和代谢方面比小血小板更活跃,具有更好的血栓形成潜力。因此,MPV高的人有血栓形成的危险。PDW是衡量血小板各向异性的指标。PCT是血小板细胞体积与血液总量之比。血小板及其利益在冠心病发病机制中起着至关重要的作用。一些研究已经证明,血小板计数的减少可能是冠心病血栓形成前状态的一个特征。这可能是血栓形成的急性段血小板消耗和下一次血栓形成的结果。
{"title":"Novel Concepts on Risk Factors Among Patients with Ischemic Stroke","authors":"Someswar Deb, Thejaswini Karanth, Pranathi R, Ajoy Krishnamurthy","doi":"10.26452/ijpib.v3i2.1386","DOIUrl":"https://doi.org/10.26452/ijpib.v3i2.1386","url":null,"abstract":"Stroke remains a chief public fitness hassle in growing international locations. Routine investigation performed to pick out Stroke is imaging, that is luxurious and no longer easy. So we want an ordinary simple take a look at to predict stroke. To have a look at the association between platelet indices, platelet matter and Ischemic Thrombotic stroke. Platelets are small discoid cell factors which can be heterogeneous with admire to size, density, age and metabolic characteristic. The ordinary person human has a platelet be counted among 1—five-four lakhs/mm3. Platelet indices or platelet quantity parameters mainly include Mean Platelet Volume (MPV), Platelet Distribution Width (PDW) and Plateletcrit (PCT). Automated mobile counters have made the platelet matter and platelet volume indices - MPV, PDW and PLCR mechanically to be had in most scientific laboratories. The MPV shows the average length of the platelets and its ordinary extent is 7.4 -10.4fl. According to current research, large platelets are enzymatically and metabolically extra active and have better thrombotic potential compared with smaller ones. Hence individuals with high MPV are said to be at danger for thrombotic activities. The PDW is a measure of platelet anisocytosis. The PCT is the ratio of the volume of platelet cells to the entire amount of blood.  Platelets and their interest have a Svital role inside the pathogenesis of coronary heart disorder. Some research has proven that decreases in platelet are counted can be a characteristic of the prothrombotic state in coronary heart ailment. This can be a result of platelet consumption in the acute segment of clot formation and next thrombosis.","PeriodicalId":170261,"journal":{"name":"International Journal of Pharmacometrics and Integrated Biosciences","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128067175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International Journal of Pharmacometrics and Integrated Biosciences
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1