Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4523
B. Jordan, S. Koike, K. Parkhotyuk, M. Olson, A. Hoppmann, D. Schilling, C. McEvoy
{"title":"Extremely Premature Infants Who Experience Inflammatory Events Have Decreased Expiratory Flow Ratios at Hospital Discharge Than Peers Without Inflammatory Events","authors":"B. Jordan, S. Koike, K. Parkhotyuk, M. Olson, A. Hoppmann, D. Schilling, C. McEvoy","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4523","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4523","url":null,"abstract":"","PeriodicalId":184436,"journal":{"name":"C18. BOSS BABY: EMERGING PRINCIPLES IN BPD AND LUNG DEVELOPMENT","volume":"354 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122796541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4521
J. Wambach, D. Wegner, J. Kitzmiller, F. V. White, H. Heins, P. Yang, A. Paul, J. Whitsett, F. S. Cole
{"title":"A Novel, Homozygous Duplication of the Surfactant Protein B Gene (SFTPB) Causes Progressive Neonatal Respiratory Failure Among Term Infant Siblings","authors":"J. Wambach, D. Wegner, J. Kitzmiller, F. V. White, H. Heins, P. Yang, A. Paul, J. Whitsett, F. S. Cole","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4521","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4521","url":null,"abstract":"","PeriodicalId":184436,"journal":{"name":"C18. BOSS BABY: EMERGING PRINCIPLES IN BPD AND LUNG DEVELOPMENT","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120947563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4527
D. Weese-Mayer, J. D. Di Fiore, D. Lake, A. Hibbs, N. Claure, J. Qiu, N. Ambalavanan, E. Bancalari, J. S. Kemp, J. Carroll, R. Martin, K. N. Krahn, A. Hamvas, S. J. Ratcliffe, N. Krishnamurthi, P. Indic, A. Dormishian, P. Dennery, J. R. Moorman, the Prematurity-Related Ventilatory Control (Pre-V
{"title":"Cardiorespiratory Physiological Trajectories in Extremely Preterm Infants","authors":"D. Weese-Mayer, J. D. Di Fiore, D. Lake, A. Hibbs, N. Claure, J. Qiu, N. Ambalavanan, E. Bancalari, J. S. Kemp, J. Carroll, R. Martin, K. N. Krahn, A. Hamvas, S. J. Ratcliffe, N. Krishnamurthi, P. Indic, A. Dormishian, P. Dennery, J. R. Moorman, the Prematurity-Related Ventilatory Control (Pre-V","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4527","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4527","url":null,"abstract":"","PeriodicalId":184436,"journal":{"name":"C18. BOSS BABY: EMERGING PRINCIPLES IN BPD AND LUNG DEVELOPMENT","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130241068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4525
B. Gustafson, M. Grayson, R. D. Britt
INTRODUCTION Premature infants have an increased risk of respiratory morbidity, including the development of recurrent wheezing. We sought to determine perinatal factors in late preterm infants associated with an increased risk of recurrent wheezing in the first 3 years of life. METHODS A retrospective chart review of infants born between 32 and 36 weeks gestational age at a tertiary hospital from 2013 to 2016 was performed. Infants with any co-morbid medical conditions were excluded. Recurrent wheezing was identified by two or more visit diagnoses for reactive airway disease, wheezing-associated respiratory infection, wheezing, or asthma during the first 3 years of life. Those with recurrent wheezing were compared to matched preterm infants who did not develop wheezing. RESULTS Three hundred and fourteen late preterm infants were included in this study; 210 infants developed recurrent wheezing while 104 did not. Gender, sex, and race were comparable between both groups. Development of wheezing was associated with positive family history of asthma (p = .014), receiving antibiotics during the neonatal period (p < .001), requiring continuous positive airway pressure for <24 h (p = .019), and receiving supplemental oxygen during the newborn period (p = .023). CONCLUSION This study retrospectively identified risk factors associated with development of wheezing in late preterm infants. Prospective studies are needed to determine whether these factors will predict recurrent wheeze in this patient population.
{"title":"Predictors of Recurrent Wheezing in Late Preterm Infants","authors":"B. Gustafson, M. Grayson, R. D. Britt","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4525","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4525","url":null,"abstract":"INTRODUCTION\u0000Premature infants have an increased risk of respiratory morbidity, including the development of recurrent wheezing. We sought to determine perinatal factors in late preterm infants associated with an increased risk of recurrent wheezing in the first 3 years of life.\u0000\u0000\u0000METHODS\u0000A retrospective chart review of infants born between 32 and 36 weeks gestational age at a tertiary hospital from 2013 to 2016 was performed. Infants with any co-morbid medical conditions were excluded. Recurrent wheezing was identified by two or more visit diagnoses for reactive airway disease, wheezing-associated respiratory infection, wheezing, or asthma during the first 3 years of life. Those with recurrent wheezing were compared to matched preterm infants who did not develop wheezing.\u0000\u0000\u0000RESULTS\u0000Three hundred and fourteen late preterm infants were included in this study; 210 infants developed recurrent wheezing while 104 did not. Gender, sex, and race were comparable between both groups. Development of wheezing was associated with positive family history of asthma (p = .014), receiving antibiotics during the neonatal period (p < .001), requiring continuous positive airway pressure for <24 h (p = .019), and receiving supplemental oxygen during the newborn period (p = .023).\u0000\u0000\u0000CONCLUSION\u0000This study retrospectively identified risk factors associated with development of wheezing in late preterm infants. Prospective studies are needed to determine whether these factors will predict recurrent wheeze in this patient population.","PeriodicalId":184436,"journal":{"name":"C18. BOSS BABY: EMERGING PRINCIPLES IN BPD AND LUNG DEVELOPMENT","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130936460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4520
L. Miller, T. Westmont, M. Rolston, A. Rindy, H. Deshmukh, N. Siegel
{"title":"Antibiotic Treatment During Infancy Alters the Gut Microbiome and Metabolites in Conjunction With the Lung Transcriptome","authors":"L. Miller, T. Westmont, M. Rolston, A. Rindy, H. Deshmukh, N. Siegel","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4520","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4520","url":null,"abstract":"","PeriodicalId":184436,"journal":{"name":"C18. BOSS BABY: EMERGING PRINCIPLES IN BPD AND LUNG DEVELOPMENT","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132816317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4524
C. Foster, P. Noreen, J. Grage, S. Kwon, L. Hird-McCorry, A. Janus, M. Davis, D. Goodman, T.A. Laguna
{"title":"Predictors for Duration of Invasive Home Mechanical Ventilation in Chronic Lung Disease of Prematurity","authors":"C. Foster, P. Noreen, J. Grage, S. Kwon, L. Hird-McCorry, A. Janus, M. Davis, D. Goodman, T.A. Laguna","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4524","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4524","url":null,"abstract":"","PeriodicalId":184436,"journal":{"name":"C18. BOSS BABY: EMERGING PRINCIPLES IN BPD AND LUNG DEVELOPMENT","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132811420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4522
I. El Alam, R. Belgacemi, I. Glass, S. Danopoulos, D. Al Alam
{"title":"Effect of Cannabinoids and Nicotine on Prenatal Human Lung​ Development","authors":"I. El Alam, R. Belgacemi, I. Glass, S. Danopoulos, D. Al Alam","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4522","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4522","url":null,"abstract":"","PeriodicalId":184436,"journal":{"name":"C18. BOSS BABY: EMERGING PRINCIPLES IN BPD AND LUNG DEVELOPMENT","volume":"195 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116607255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4526
C. Gunatilaka, C.L. Mckenzie, E. Hysinger, Q. Xiao, N. Higano, J. Woods, A. Bates
{"title":"The Effect of Neonatal Tracheomalacia on Aerosolized Drug Delivery","authors":"C. Gunatilaka, C.L. Mckenzie, E. Hysinger, Q. Xiao, N. Higano, J. Woods, A. Bates","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4526","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4526","url":null,"abstract":"","PeriodicalId":184436,"journal":{"name":"C18. BOSS BABY: EMERGING PRINCIPLES IN BPD AND LUNG DEVELOPMENT","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116676163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}