Pub Date : 2021-02-25DOI: 10.1093/oso/9780198829539.003.0008
Á. J. Láruson, F. A. Reed
This chapter addresses different approaches to quantifying genetic divergence between populations. It discusses the concept of “missing heterozygosity” and uses this to quantify the level of divergence between two populations with a measure called FST. The chapter works through how to determine a population of origin from blue whale data and touches on the concept of DNA fingerprinting to identify individuals.
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Here non-random shifts in allele frequencies over time are introduced, as well as how to incorporate varying levels of selection into a model of a single population through time. This chapter highlights the difference between weak and strong selection, the dynamics of single allele versus genotype-level selection, and how selection strength and population size affect allele frequency distributions over time. Finally the inference of the selection coefficient from allele frequency data is discussed, alongside the concepts of overdominance and underdominance.
{"title":"Adaptation and Natural Selection","authors":"Á. J. Láruson, F. A. Reed","doi":"10.2307/j.ctt7ztx9b.5","DOIUrl":"https://doi.org/10.2307/j.ctt7ztx9b.5","url":null,"abstract":"Here non-random shifts in allele frequencies over time are introduced, as well as how to incorporate varying levels of selection into a model of a single population through time. This chapter highlights the difference between weak and strong selection, the dynamics of single allele versus genotype-level selection, and how selection strength and population size affect allele frequency distributions over time. Finally the inference of the selection coefficient from allele frequency data is discussed, alongside the concepts of overdominance and underdominance.","PeriodicalId":20383,"journal":{"name":"Population Genetics with R","volume":"113 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85493811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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