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冬凌草甲素对人软骨肉瘤SW-1353细胞的增殖和凋亡的影响及其机制探究 冬凌草甲素对人软骨肉瘤SW-1353细胞的增殖和凋亡的影响及其机制探究
Pub Date : 2024-06-15 DOI: 10.16252/j.cnki.issn1004-0501-2024.06.006
许超 | 李震 | 孟迪 | 李鋆
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引用次数: 0
硝酸甘油联合三七总皂苷对急性心肌梗死大鼠模型的治疗作用 硝酸甘油联合三七总皂苷对急性心肌梗死大鼠模型的治疗作用
Pub Date : 2021-09-15 DOI: 10.16252/j.cnki.issn1004-0501-2021.09.006
梁文怡 | 孔然 | 谢丽映 | 李婷 | 林晓滨 | 戴玮 | 潘丽欣 | 吴新艺 | 汪鹏
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引用次数: 0
Primary resection and anastomosis with intraoperative colonic defecation in left colonic cancer with complete obstruction 完全性梗阻左结肠癌一期切除吻合术中结肠排便
Pub Date : 2009-05-31 DOI: 10.3760/CMA.J.ISSN.1673-4203.2009.05.007
Xiao-an Wang, Ya-jun Wang, Fei Lı, Yu Fang, Ang Li, Dong-bin Liu, Jia-bang Sun
Objective To assess the value of primary resection and anastomosis with intraoperative colonic defecation in the patients with obstructive left colonic cancer. Methods From January 2000 to January 2008, 39 patients undergoing emergency laparotomy for left colonic cancers with complete obstruction were analyzed retrospectively. Results The patients were 25 males and 14 females, with a median age of 68.5 years (range: 57~78 years). The primary tumors were located at splenic flexure (3/7.7%), descending colon (8/20.5%), sigmoid colon (15/38.5%), boundary of sigmoid colon and rectum (8/20.5%), and superior segment of rectum (5/12.8%). Primary resection and anastomosis with intraoperative colonic de-fection were performed in 18 patients with left hemicolectomy, 13 patients with sigmoid colectomy and 8 pa-tients with anterior resection. Early complications included wound infection in 4 patients (wound disruption in 1 patient) and pulmonary infection in 5 patients. One patient complicated with anastomotic leakage and intra-abdominal abscess died of tumor metastasis after reoperation. Another one died of respiratory failure secondary to pulmonary infection. Morbidity and mortality was 25.6% and 5.1% respectively. Conclusion Primary resection with intraoperative colonic defecation can be applied to patients with malignant colonic complete obstruction with good operative results. Key words: colonic carcinoma; intestinal obstruction; resection and anastomosis
目的探讨梗阻性左结肠癌一期切除吻合术中结肠排便的价值。方法回顾性分析2000年1月至2008年1月39例左结肠癌完全性梗阻急诊开腹手术患者的临床资料。结果男性25例,女性14例,年龄57~78岁,中位年龄68.5岁。原发肿瘤位于脾曲(3/7.7%)、降结肠(8/20.5%)、乙状结肠(15/38.5%)、乙状结肠与直肠交界处(8/20.5%)、直肠上段(5/12.8%)。对18例左半结肠切除术、13例乙状结肠切除术和8例前结肠切除术行一期结肠切除吻合术中结肠排便。早期并发症包括4例伤口感染(1例伤口破裂)和5例肺部感染。1例术后并发吻合口瘘腹腔内脓肿,再手术后肿瘤转移死亡。另一人死于肺部感染继发的呼吸衰竭。发病率和死亡率分别为25.6%和5.1%。结论术中结肠排便一期切除可用于恶性结肠完全性梗阻患者,手术效果良好。关键词:结肠癌;肠梗阻;切除与吻合
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