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JOURNAL OF CORONA VIRUS COVID19最新文献

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Lifestyle Changes For People With Non Communicable Diseases In The COVID-19 era: A Survey Conducted Around The World COVID-19时代非传染性疾病患者生活方式的改变:一项在世界各地进行的调查
Pub Date : 1900-01-01 DOI: 10.47690/jcv.2021.1404
L. H., B. R.
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引用次数: 0
Vaccination Attitudes and Impact of the Second COVID-19 Lockdown on Mood, Mental State, and Exercise Habits in Germany: A Cross-Sectional Study 疫苗接种态度和第二次COVID-19封锁对德国情绪、精神状态和运动习惯的影响:一项横断面研究
Pub Date : 1900-01-01 DOI: 10.47690/jcv.2021.1402
G. H, M. D., Adamovic I, Blob H-B, D. S, Kühnlein P, Mäffert R, Raabe A, Sterner M-G, Zintl K, Zühlke C, Đogaš Z
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引用次数: 0
Striking Biochemical Markers in Laboratory Diagnosis for People in COVID-19 Pandemic 在COVID-19大流行人群的实验室诊断中显著的生化标志物
Pub Date : 1900-01-01 DOI: 10.47690/jcv.2021.1405
I. K, Muge Mk, Erdi At
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引用次数: 0
Laser Therapy in the Complex Prevention and Treatment of COVID-19 (Preliminary Results) 激光治疗在新型冠状病毒复合防治中的应用(初步结果)
Pub Date : 1900-01-01 DOI: 10.47690/jcv.2021.1103
Mikhaylov Va
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引用次数: 0
Prognostic Factors in Patients with AKI and COVID-19 AKI和COVID-19患者的预后因素
Pub Date : 1900-01-01 DOI: 10.47690/jcv.2021.1301
Tahereh Sabaghian, Almasi Mh, M. Raoufi, H. Ebrat, Alavi Aa, O. Moradi, F. Masbough, A. Falsafi, S. Yaghmaei
Prognostic Factors in Patients with AKI and COVID-19. ABSTRACT Background : Acute kidney injury is challenging in the context of the COVID-19 pandemic. Up to 30 % of critically ill COVID-19 pa tients develop AKI. Thus, it is imperative to determine what factors may predict the likelihood of these patients developing more severe and potentially life-threatening conditions. Objective : The aim of this study is to investigate the clinical and computed tomography features associated with poor prognostic factors in COVID-19 patients developing AKI. We also aimed to investigate chest CT score and its pattern in AKI patients in the COVID-19 setting. Materials and Methods : 415 patients with COVID-19 pneumonia were enrolled. 64 patients have been excluded due to a history of chronic kidney disorders. Finally, 351 patients, including 100 AKI cases and 251 non-AKI cases, were enrolled. The chest CT images and clinical data of them were reviewed and compared. The CT scores and the risk factors associated with disease severity were discussed. Results: Compared with the non-AKI group, the AKI patients had older ages and a higher incidence of certain comorbidities, such as hypertension and cardiovascular disorders. In AKI patients, the value of inflammatory markers, e.g., CRP, LDH, PCT, and Lactate level were significantly higher than those of the ordinary patients (P<0.05). In addition, the AKI patients showed higher incidences of lymphopenia (P=0.019) and leukocytosis (P=0.023). In the AKI group, the CT-scores were significantly higher than those of the non-AKI group (P < 0.001), and severe CT- scores were mainly associated with AKI. ROC analysis showed that 71.4 % sensitiv ity and 90 % specificity for CT scores higher than 13 in the AKI group. Out of all measured parameters, CT-score and the level of PCT, lactate, and WBC were the most reliable factors for predicting mortality in AKI patients. Conclusions: There are significant differences in clinical symp -toms, laboratory examinations, and CT manifestations between the AKI and non-AKI patients in the COVID-19 setting. Many factors are associated with the severity of the illness, which can help clinicians assess patients' prognosis.
AKI和COVID-19患者的预后因素背景:在COVID-19大流行背景下,急性肾损伤具有挑战性。高达30%的危重COVID-19患者会发展为AKI。因此,必须确定哪些因素可以预测这些患者发展成更严重和可能危及生命的疾病的可能性。目的:本研究的目的是探讨与COVID-19发生AKI的患者预后不良因素相关的临床和计算机断层扫描特征。我们还旨在调查COVID-19背景下AKI患者的胸部CT评分及其模式。材料与方法:纳入415例COVID-19肺炎患者。64例患者因有慢性肾脏疾病病史而被排除在外。最终纳入351例患者,包括100例AKI病例和251例非AKI病例。复习比较两例患者的胸部CT图像及临床资料。讨论了CT评分及与疾病严重程度相关的危险因素。结果:与非AKI组相比,AKI患者年龄更大,高血压、心血管疾病等合并症的发生率更高。AKI患者CRP、LDH、PCT、乳酸水平等炎症指标均显著高于普通患者(P<0.05)。此外,AKI患者淋巴细胞减少(P=0.019)和白细胞增多(P=0.023)的发生率较高。AKI组CT评分显著高于非AKI组(P < 0.001),重度CT评分主要与AKI相关。ROC分析显示,AKI组CT评分高于13的敏感性为71.4%,特异性为90%。在所有测量参数中,ct评分和PCT、乳酸和白细胞水平是预测AKI患者死亡率的最可靠因素。结论:新冠肺炎背景下AKI与非AKI患者在临床症状、实验室检查和CT表现上存在显著差异。许多因素与疾病的严重程度有关,这可以帮助临床医生评估患者的预后。
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引用次数: 0
Immunity and Spiritual Care in Prevention of Covid 19 Covid - 19预防中的免疫与精神关怀
Pub Date : 1900-01-01 DOI: 10.47690/jcv.2021.1401
Karati D
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引用次数: 1
Diagnosis and Management of TCM On Infected Or Suspected Patients with Covid-19 ------48 Cases Study in UK 英国48例新型冠状病毒感染或疑似患者的中医诊断与管理------
Pub Date : 1900-01-01 DOI: 10.47690/jcv.2021.1403
J. D
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引用次数: 0
Characteristics of COVID-19 in Pediatric Patients with Malignancy in Sulaymaniyah Governorate, Kurdistan Region of Iraq 伊拉克库尔德斯坦地区苏莱曼尼亚省儿童恶性肿瘤患者COVID-19特征
Pub Date : 1900-01-01 DOI: 10.47690/JCV.2021.1104
Al odda Bka, Mohammed Zb, Muhealddina Dl, Abdullah Km, Qadir Ao, Shrif Ra, Fakrealdeen Ga, Al odda Zbk, Al odda Gbk
BACKGROUND: A recent human’s pandemic of respiratory disease caused by a novel (new) coronavirus that rapidly spreads in the community and may causing life threating complications. All those exposed to it is at risk of becoming infected and getting COVID-19. Cancer Patients may be more likely at risk to getting the infection and developing life threating morbidity and even death as those cancer patients may have weakened immunity either because of the cancer treatment or direct effect of the disease. OBJECTIVE: To obtain local data on the pattern of children and adolescent with cancer on treatment who have been infected with SARS-CoV-2 in our community and compare it with that of noncancerous patients. Journal Home: https://www.scienceworldpublishing.org/journals/journal-of-corona-virus-/COVID19 2/7 Journal of Corona Virus Volume: 1.1 PATIENTS AND METHODS: A prospective study conducted on 54 pediatric patients with cancer during their treatment with chemotherapy that developed RT-PCR approved COVID-19 in Sulaymaniyah Governorate-Kurdistan region of Iraq from April 2020 to October 2020 were carried out to analyze the demographic features and their clinical manifestation. Data analyzed using SPSS software; version 13 and P-value obtained by Chi-square test. RESULTS: The median age at diagnosis was about 7 and peak age incidence occurred in adolescent between 13-17 years old with slightly female predominance. There was no correlation between gender and severity; patients with hematological malignancies seem to have more severe COVID-19 manifestation than solid tumor. CONCLUSION: Overall morbidity and mortality from COVID-19 in cancer patients is seem to be similar to noncancerous patients. INTRODUCTION Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19), the respiratory illness responsible for the COVID-19 pandemic [1, 2]. SARS-CoV-2 is a member of the family Coronaviridae and orders Nidovirales, is an enveloped and positive-sense single-stranded RNA (+ssRNA) virus[3]. The incidence of SARS-CoV-2 infection is seen most often in adult male patients with the median age of the patients was between 34 and 59 years [4,5], SARS-CoV-2 is also more likely to infect people with chronic comorbidities such as cardiovascular and cerebrovascular diseases and diabetes [6]. The highest proportion of severe cases occurs in adult’s ≥60 years of age, and in those with certain underlying conditions, such as cardiovascular and cerebrovascular diseases and diabetes [4, 5]. Severe manifestations maybe also associated with coinfections of bacteria and fungi [6]. Fewer COVID-19 cases have been reported in children less than 15 years [5, 7, 8]. In a study of 425 COVID-19 patients in Wuhan, published on January 29, there were no cases in children under 15 years of age [9], Nevertheless, 28 pediatric patients have been reported by January 2020. The clinical features of infected pediatric patients vary, but
背景:最近发生了一起由新型冠状病毒引起的人类呼吸道疾病大流行,该病毒在社区中迅速传播,并可能导致危及生命的并发症。所有接触到它的人都有被感染和感染COVID-19的风险。由于癌症治疗或癌症的直接影响,这些癌症患者的免疫力可能会减弱,因此更有可能受到感染并发展成危及生命的疾病甚至死亡。目的:了解本地区接受治疗的儿童和青少年癌症患者感染SARS-CoV-2的情况,并与非癌症患者进行比较。患者与方法:对2020年4月至2020年10月伊拉克苏莱曼尼亚省-库尔德斯坦地区54例经RT-PCR批准的2019冠状病毒病(COVID-19)化疗期间的儿童癌症患者进行前瞻性研究,分析其人口学特征及临床表现。数据分析采用SPSS软件;版本13,p值由卡方检验得到。结果:诊断时中位年龄约为7岁,发病高峰发生在13-17岁的青少年,女性略占优势。性别与严重程度无相关性;血液系统恶性肿瘤患者的COVID-19表现似乎比实体瘤更严重。结论:2019冠状病毒病在癌症患者中的总体发病率和死亡率与非癌症患者相似。严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)是导致2019冠状病毒病(COVID-19)的病毒,COVID-19是导致COVID-19大流行的呼吸道疾病[1,2]。SARS-CoV-2是冠状病毒科和奈多病毒目的成员,是一种包膜阳性单链RNA (+ssRNA)病毒[3]。SARS-CoV-2感染的发生率多见于成年男性患者,患者的中位年龄在34 ~ 59岁之间[4,5],SARS-CoV-2也更容易感染心脑血管疾病、糖尿病等慢性合并症患者[6]。严重病例比例最高的是年龄≥60岁的成年人,以及有一定基础疾病的人群,如心脑血管疾病和糖尿病[4,5]。严重的表现也可能与细菌和真菌的共感染有关[6]。15岁以下儿童中报告的COVID-19病例较少[5,7,8]。1月29日发表的一项对武汉市425例COVID-19患者的研究显示,15岁以下儿童无病例[9],但截至2020年1月,已报告28例儿科患者。小儿感染患者的临床特征各不相同,但多数症状较轻,无发热、肺炎,预后良好[10]。另一项研究发现,虽然儿童有放射学上的磨玻璃肺混浊,但患者无症状[9]。总之,儿童可能不太可能被感染,或者即使被感染,表现也比成人温和;因此,他们的父母可能不会寻求治疗,从而低估了这一年龄组的COVID-19发病率。血液病或实体恶性肿瘤患者可能更有可能感染并发展成危及生命的疾病甚至死亡,因为这些癌症患者可能由于癌症治疗或疾病的直接影响而削弱了免疫力。对于接受化疗的活动性恶性肿瘤患者,特别是年幼的儿童和青少年,COVID-19的潜在影响和严重程度仍然存在疑问,主要问题是如何继续或停止这些患者正在进行的化疗,因此我们做了这项研究,试图回答这个重要的问题。患者与方法在2020年4月至2020年10月期间,对伊拉克库尔德斯坦地区苏莱曼尼亚省Hiwa癌症中心54例血液学恶性肿瘤和实体肿瘤患者进行了为期6个月的前瞻性研究,分析了儿童癌症化疗患者中SARS-CoV-2的人口学特征、临床表现和后果。基于实时聚合酶链反应(RT-PCR)检测鼻咽拭子病毒抗原诊断SARS-CoV-2。纳入标准包括所有接受化疗的血液学和实体恶性肿瘤的儿童患者,不分性别,年龄在18岁以下,通过鼻咽拭子RT-PCR诊断为SARS-CoV-2的完整记录数据。 排除标准包括鼻咽拭子中所有SARS-CoV-2 RT-PCR阴性的患者、血清学阳性(SARSCoV-2 IgG和/或IgM)或放射学未见SARS-CoV-2 RT-PCR的诊断为COVID-19的患者、未接受化疗的患者以及其他合并症如代谢或心脏疾病的患者。所有纳入的患者都有详细的临床病史,包括合并症;测量生命体征,血氧饱和度(SpO2)评估疾病的严重程度,特别是呼吸道症状。然后进行血液学检查(全血细胞计数和血膜)、生化检查(肝肾上腺功能、CRP、乳酸脱氢酶和铁蛋白水平、d -二聚体、血清电解质和血培养)、放射学检查(胸部x光片和胸部计算机断层扫描)、鼻咽拭子SARS-CoV-2 RTPCR。按照《2019-nCoV诊疗方案》[11,12]将病情严重程度分为三类;轻度至中度(轻度症状至轻度肺炎);严重(呼吸困难,缺氧,或影像学上超过50%的肺部受累);危重(呼吸衰竭、休克或多器官系统功能障碍),在我们的研究中,也根据放射检查结果将患者分为正常和异常,包括任何异常(双侧、外周、模糊和毛玻璃混浊、实变、胸腔积液)。Journal Home: https://www.scienceworldpublishing.org/journals/journal-of-corona-virus-/COVID19 3/7 Journal of Corona Virus Volume:1.1肺萎陷)无任何胸片或胸部CT扫描,则患者按当地指南治疗,多采用抗生素和支持性护理。本研究经Hiwa医院伦理审查委员会批准。将数据输入Excel表格,然后转入spss -描述性分析;数据分析采用SPSS (Statistical package for social sciences)软件;版本13和P值经卡方检验,P值小于0.05认为显著。结果54例不同类型血液系统恶性肿瘤及实体瘤患儿平均年龄为10.2岁(标准差为11.6),最小年龄为2.1岁,最大年龄为17岁(范围为14.9岁),中位年龄为7岁。大多数COVID-19病例发生在13至17岁的青少年(37.4%),其次是9至12岁的儿童(27.77%)。表1显示了我们患者的年龄分布(表1)。表1:年龄分布年龄频率% 1-4 8 14.81 5-8 11 20.37 9-12 15 27.77 13-17 20 37.4女孩略多于男孩,女性占55.55%(30),男性占44.45%(24),男女比例为0.8:1。图1显示了我们患者的性别分布(图1)。从图2可以看出,我们的儿童COVID-19患者中,大多数患者最初诊断为急性淋巴母细胞白血病,少数为淋巴瘤,27例(50%)为急性淋巴母细胞白血病(ALL), 12例(22.22%)为实体瘤,9例(16.66%)为急性髓系白血病(AML),只有6例(11.11%)为淋巴瘤(图2)。主要表现为发热39例(72.22%),核心体温37.8 ~ 40.2℃,其次为咳嗽23例(42.6%),打喷嚏10例(18.52%),呼吸窘迫5例(9.26%),恶心/呕吐4例(7.41%),腹泻2例(3.7%)。表2显示了COVID-19临床表现的频率和百分比(表2)。从图3所示的COVID-19严重程度来看,轻至中度45例(83.33%),重度7例(12.96%),危重2例(3.7%)。表2新冠肺炎临床表现频次及百分比临床表现频次百分比发热39 72.22咳嗽23 42.6打喷嚏10 18.52呼吸窘迫5 9.26恶心呕吐4 7.41腹泻2 3.7图3根据《2019-nCoV诊疗方案》分类的疾病严重程度分布[12,13]https://www.scienceworldpublishing.org/journals/journal-of-corona-virus-/COVID19 4/7冠状病毒杂志
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引用次数: 1
Design Strategies To Improve Healthcare Worker Safety In Doffing Units: An Evidence Based Study In Bio secure Mobile Doffing Unit 设计策略,以提高卫生保健工作者的安全滴落单位:在生物安全移动滴落单位的证据为基础的研究
Pub Date : 1900-01-01 DOI: 10.47690/jcv.2021.1302
Majeed Sa, Haneefa S, Reghukumar A, M. S, Kiron Js
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引用次数: 0
期刊
JOURNAL OF CORONA VIRUS COVID19
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