Pub Date : 2019-09-10DOI: 10.1007/978-3-642-41714-6_120258
Yann Le Bohec
{"title":"Landing","authors":"Yann Le Bohec","doi":"10.1007/978-3-642-41714-6_120258","DOIUrl":"https://doi.org/10.1007/978-3-642-41714-6_120258","url":null,"abstract":"","PeriodicalId":299675,"journal":{"name":"DANCE, ARCHITECTURE AND ENGINEERING","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122552172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Changliu Liu, Te Tang, Hsien-Chung Lin, M. Tomizuka
MOF nanocarrier of CMD can efficiently weaken the cellular antioxidant capacity by depleting the overexpressed glutathione, simultaneously leading to the decomposition of the framework structure and the release of the encapsulated dihydroartemisinin. As a result, the damaged antioxidant defense system of cancer cells reduces its effect on oxidative stress alleviation and strengthens the therapeutic efficacy of dihydroartemisinin. On contrast, the low concentration of cellular glutathione in normal cells protects them from dihydroartemisinin-induced cytotoxicity by decelerating the drug release. In vivo results demonstrate that CMD could completely suppress the tumor growth in mice and show no evidence of toxicity, providing an effective strategy for the practical usage of dihydroartemisinin in cancer therapy.
{"title":"Framework","authors":"Changliu Liu, Te Tang, Hsien-Chung Lin, M. Tomizuka","doi":"10.18356/6ec4b733-en","DOIUrl":"https://doi.org/10.18356/6ec4b733-en","url":null,"abstract":"MOF nanocarrier of CMD can efficiently weaken the cellular antioxidant capacity by depleting the overexpressed glutathione, simultaneously leading to the decomposition of the framework structure and the release of the encapsulated dihydroartemisinin. As a result, the damaged antioxidant defense system of cancer cells reduces its effect on oxidative stress alleviation and strengthens the therapeutic efficacy of dihydroartemisinin. On contrast, the low concentration of cellular glutathione in normal cells protects them from dihydroartemisinin-induced cytotoxicity by decelerating the drug release. In vivo results demonstrate that CMD could completely suppress the tumor growth in mice and show no evidence of toxicity, providing an effective strategy for the practical usage of dihydroartemisinin in cancer therapy.","PeriodicalId":299675,"journal":{"name":"DANCE, ARCHITECTURE AND ENGINEERING","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115970019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2009-12-31DOI: 10.3138/9781442676879-008
B. Savinkov
Chapter Ten Discussions and conclusions 10.1 Introduction: The main characteristics of new complexity scores
10.1引言:新复杂性评分的主要特点
{"title":"Part Three","authors":"B. Savinkov","doi":"10.3138/9781442676879-008","DOIUrl":"https://doi.org/10.3138/9781442676879-008","url":null,"abstract":"Chapter Ten Discussions and conclusions 10.1 Introduction: The main characteristics of new complexity scores","PeriodicalId":299675,"journal":{"name":"DANCE, ARCHITECTURE AND ENGINEERING","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2009-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116731663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5040/9781350185227.0014
{"title":"The Art of Infrastructure: reflection conversation with John Bingham-Hall","authors":"","doi":"10.5040/9781350185227.0014","DOIUrl":"https://doi.org/10.5040/9781350185227.0014","url":null,"abstract":"","PeriodicalId":299675,"journal":{"name":"DANCE, ARCHITECTURE AND ENGINEERING","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130312497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5040/9781350185227.0016
{"title":"Whenness: reflection conversation with Richard Sennett","authors":"","doi":"10.5040/9781350185227.0016","DOIUrl":"https://doi.org/10.5040/9781350185227.0016","url":null,"abstract":"","PeriodicalId":299675,"journal":{"name":"DANCE, ARCHITECTURE AND ENGINEERING","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126576942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5040/9781350185227.0015
{"title":"Choreography as questioning the knowable: reflection conversation with Liz Lerman","authors":"","doi":"10.5040/9781350185227.0015","DOIUrl":"https://doi.org/10.5040/9781350185227.0015","url":null,"abstract":"","PeriodicalId":299675,"journal":{"name":"DANCE, ARCHITECTURE AND ENGINEERING","volume":"414 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"113989114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5040/9781350185227.0017
{"title":"‘I am going to try to be a choreographer in the world’: reflection conversation with Dianne McIntyre","authors":"","doi":"10.5040/9781350185227.0017","DOIUrl":"https://doi.org/10.5040/9781350185227.0017","url":null,"abstract":"","PeriodicalId":299675,"journal":{"name":"DANCE, ARCHITECTURE AND ENGINEERING","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121755219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5040/9781350185227.0008
{"title":"Dance as conversation with the somatic","authors":"","doi":"10.5040/9781350185227.0008","DOIUrl":"https://doi.org/10.5040/9781350185227.0008","url":null,"abstract":"","PeriodicalId":299675,"journal":{"name":"DANCE, ARCHITECTURE AND ENGINEERING","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128152433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.5040/9781350185227.0012
{"title":"Lingering in Dwelling, Residing in Wandering","authors":"","doi":"10.5040/9781350185227.0012","DOIUrl":"https://doi.org/10.5040/9781350185227.0012","url":null,"abstract":"","PeriodicalId":299675,"journal":{"name":"DANCE, ARCHITECTURE AND ENGINEERING","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129047910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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