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Fluid therapy in neurotrauma: basic and clinical concepts. 神经创伤的液体疗法:基本和临床概念。
Pub Date : 2014-01-01 DOI: 10.7175/rhc.v5i1.636
Hernando Raphael Alvis-Miranda, Andres M Rubiano, Juan C Puyana, Gabriel Alcala-Cerra, Luis Rafael Moscote-Salazar

The patient with head trauma is a challenge for the emergency physician and for the neurosurgeon. Currently traumatic brain injury constitutes a public health problem. Knowledge of the various therapeutic strategies to provide support in the prehospital and perioperative are essential for optimal care. Rapid infusion of large volumes of crystalloids to restore blood volume and blood pressure quickly is now the standard treatment for patients with combined TBI and HS The fluid in patients with brain and especially in the carrier of brain injury is a critical topic; we present a review of the literature about the history, physiology of current fluid preparations, and a discussion regard the use of fluid therapy in traumatic brain injury and decompressive craniectomy.

颅脑外伤患者对急诊医师和神经外科医生都是一个挑战。目前,创伤性脑损伤已成为一个公共卫生问题。了解院前和围手术期提供支持的各种治疗策略对最佳护理至关重要。快速输注大量晶体物质,迅速恢复血容量和血压是目前TBI合并HS患者的标准治疗方法,颅脑患者特别是脑损伤携带者的体液是一个重要的课题;我们回顾了有关液体制剂的历史、生理学的文献,并讨论了液体疗法在创伤性脑损伤和颅骨减压术中的应用。
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引用次数: 1
Data Sources Regarding the Nonmedical Use of Pharmaceutical Opioids in the United States. 美国阿片类药物非医疗使用的数据来源。
Pub Date : 2014-01-01 DOI: 10.7175/rhc.v5i1.883
Teresa Schmidt, Amanuel Zimam, Alexandra Nielsen, Wayne Wakeland

Objective: Recent increases in the nonmedical use of pharmaceutical opioids and the adverse outcomes associated with them have stimulated a large amount of research and data collection on this public health problem. Systematic organization of the available data sources is needed to facilitate ongoing research, analysis, and evaluation. This work offers a systematic categorization of data sources regarding the nonmedical use of pharmaceutical opioids in the United States.

Methods: A list of keywords regarding the nonmedical use of pharmaceutical opioids was used to conduct systematic searches in PubMed®. Filtration of search results generated 92 peer-reviewed academic articles, published between January 1995 and April 2012, as well as a number of primary data sources. Lists of topics were developed independently by two researchers which were later compared and consolidated. All sources were then categorized according to their relevance to each of these topics and according to their capacity for geographical and longitudinal trend analysis.

Results: Tables cataloging data sources can be used to identify data relevant to specific topics in diversion, nonmedical use, and adverse outcomes associated with pharmaceutical opioids, and they illustrate global trends in data coverage, identifying several topics that have minimal data. A network diagram illustrates global trends in data coverage, showing variation among sources in the number of topics they cover, as well as variation among topics in the number of sources that cover them.

Conclusions: The categorization of data sources is hoped to facilitate ongoing research, analysis, and evaluation of this public health problem by serving as a guide for researchers, policy makers, and others who seek data regarding the nonmedical use of pharmaceutical opioids in the United States.

目的:最近药物类阿片非医疗使用的增加及其相关的不良后果刺激了对这一公共卫生问题的大量研究和数据收集。需要系统地组织可用的数据源,以促进正在进行的研究、分析和评价。这项工作提供了一个系统的数据来源分类关于非医疗使用的药物阿片类药物在美国。方法:采用与阿片类药物非医疗使用相关的关键词列表在PubMed®系统检索。对搜索结果的过滤产生了1995年1月至2012年4月期间发表的92篇经同行评审的学术文章,以及一些主要数据来源。主题清单是由两位研究者独立制定的,后来进行了比较和整合。然后根据所有来源与每一个主题的相关性以及根据其进行地理和纵向趋势分析的能力对它们进行分类。结果:数据来源目录表可用于确定与药物类阿片转移、非医疗使用和不良后果相关的特定主题相关的数据,并说明数据覆盖的全球趋势,确定数据最少的几个主题。网络图说明了数据覆盖的全球趋势,显示了不同来源所涵盖的主题数量的变化,以及不同主题所涵盖的来源数量的变化。结论:希望对数据来源进行分类,通过为研究人员、政策制定者和其他寻求有关美国药物阿片类药物非医疗使用数据的人提供指南,促进对这一公共卫生问题的持续研究、分析和评估。
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引用次数: 6
Pediatric Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. 小儿肌痛性脑脊髓炎/慢性疲劳综合征。
Pub Date : 2012-01-01
Leonard A Jason, Kristen Barker, Abigail Brown

Research on pediatric Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is reviewed in this article. Many recent articles in this area highlight the existence of key differences between the adult and pediatric forms of the illness. This review article provides an overview of pediatric ME/CFS, including epidemiology, diagnostic criteria, treatment, and prognosis. Challenges to the field are identified with the hope that in the future pediatric cases of ME/CFS can be more accurately diagnosed and successfully managed.

本文回顾了有关小儿肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)的研究。该领域的许多最新文章都强调了成人和小儿疾病之间存在的主要差异。这篇综述文章概述了儿科 ME/CFS 的情况,包括流行病学、诊断标准、治疗和预后。文章指出了这一领域所面临的挑战,希望未来儿科 ME/CFS 病例能得到更准确的诊断和成功的管理。
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引用次数: 0
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Reviews in Health Care
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