Malena Gergovska, K. Semkova, J. Kazandjieva, N. Tsankov
Abstract A large number of contact allergic reactions to benzocaine have been reported since its introduction to the pharmaceutical market as an active ingredient in different over-the-counter anesthetic ointments. Benzocaine is used as a key ingredient in many pharmaceuticals, such as products for oral ulcers, wound and burn preparations, sunburn remedies, hemorrhoidal preparations, oral and gingival products, sore throat sprays/lozenges, callous and wart remedies, creams for treatment of poison ivy dermatitis, tooth ache and denture irritation products. We present a 56-year-old Caucasian male with chronic rash, accompanied by intense itching in the perianal area. The lesions occurred two months earlier and the patient was treated with a wide range of topical antifungals, antibiotics and corticosteroids, with temporary improvement. The skin lesions were consistent with chronic allergic contact dermatitis. The patient denied using any topical preparations other than those prescribed by his dermatologist. Patch testing with the European baseline series was performed. A strongly positive reaction to benzocaine was identified on reading days 2 and 3. Targeted history showed intermittent use of benzocaine anti-hemorrhoidal cream to treat concomitant hemorrhoids. Benzocaine was discontinued and treatment with methylprednisolone aceponate 0.1% was initiated, resulting in significant improvement. No relapse was observed at 3-month follow-up. In conclusion, patients with confirmed benzocaine allergy should pay special attention to product labels and avoid products that contain benzocaine and its related substances. All products labelled as “anaesthetic” or “caine” should be suspected of containing benzocaine or related compounds. Patient education and awareness are critical to avoid further episodes and relapses. Sažetak Uvod. U svetskoj stručnoj literaturi opisan je veliki broj slučajeva kontaktne senzibilizacije izazvane lokalnom upotrebom benzokaina. Ovo se može objasniti velikim brojem lokalnih farmaceutika prisutnih na farmaceutskom tržištu koji se bez lekarskog recepta mogu nabaviti, a koji u svom sastavu sadrže lokalni anestetik. Benzokain predstavlja ključnu aktivnu supstanciju u mnogim preparatima koji se koriste za lečenje oralnih ulceracija, promena na desnima, bolnih upala zuba i grla, opekotina, rana, hemoroida. Nalazi se u velikom broju preparata za ispiranje usta, ali i lokalnih pripravka za lečenje kalusa i klavusa. Prikaz slučaja. Prikazujemo 56 godina staru pacijentkinju čija je glavna tegoba bila intenzivan svrab u perianalnom predelu. Dva meseca pre pregleda kod nas, pored osećaja svraba, na koži perianalne regije pojavilo se intenzivno crvenilo. U tom vremenskom periodu, u terapiju je uvođen veći broj različitih preparata za lokalno lečenje: antimikotici, antibiotici, kortikosteroidi. Poboljšanje je bilo privremeno, tako da su u momentu pregleda promene odgovarale kliničkoj slici kontaktnog dermatitisa. Pacijentkinja je negirala upot
自从苯佐卡因作为一种活性成分被引入医药市场以来，大量的接触性过敏反应已被报道。苯佐卡因被用作许多药物的关键成分，例如用于口腔溃疡的产品、伤口和烧伤制剂、晒伤疗法、痔疮制剂、口腔和牙龈产品、喉咙痛喷雾剂/含片、痂和疣疗法、治疗毒葛皮炎的药膏、牙痛和刺激假牙的产品。我们提出一个56岁的高加索男性慢性皮疹，并伴有强烈的瘙痒在肛周区域。病变发生在两个月前，患者接受了广泛的局部抗真菌药、抗生素和皮质类固醇治疗，暂时得到改善。皮肤损伤符合慢性过敏性接触性皮炎。病人否认使用除皮肤科医生开的处方外的任何外用制剂。采用欧洲基线系列进行斑贴试验。在阅读第2天和第3天，发现对苯佐卡因有强烈的积极反应。目标病史显示间歇性使用苯佐卡因抗痔膏治疗伴发性痔疮。停用苯佐卡因，并开始使用0.1%的乙酰甲泼尼龙治疗，结果显著改善。随访3个月无复发。综上所述，确诊苯佐卡因过敏的患者应特别注意产品标签，避免使用含有苯佐卡因及其相关物质的产品。所有标有“麻醉剂”或“卡因”的产品都应怀疑含有苯佐卡因或相关化合物。患者教育和意识对于避免进一步发作和复发至关重要。Sažetak Uvod。[8] [1] [j] [j] [j] [j] [j] [j] [j] [j] [j] [j] [j]。Ovo se može objasniti velikim brojem lokalnih farmaceutika prisutnih na farmaceutskom tržištu koji se bez lekarskog recepta mogu nabaviti, a koji u sastavu sadrže lokalni anestetik。本研究的主要内容为:口腔溃疡、口腔黏膜炎、口腔黏膜炎、口腔黏膜炎、口腔黏膜炎、口腔黏膜炎、口腔黏膜炎、口腔黏膜炎、口腔黏膜炎、口腔黏膜炎、痔疮。纳拉兹认为，如果你准备好了，你就会有一个好朋友，你就会有一个好朋友，你就会有一个好朋友。Prikaz slučaja。Prikazujemo 56 godina staru pacijentkinju <e:1> ija je glavna tegoba bila intenzivan svrab u perannom predelu。Dva meseca pre pregleda kod nas, pore osećaja svraba, na koži perianne regije pojavilo se intenzivno crvenilo。U tom vremenskom periodu, U terapiju je uvođen veći broj razli<e:1> with preparata za lokalno le<e:1> enje:抗菌，抗生素，kortikosteroidi。Poboljšanje je billion priremeno, tako da suu momentu pregleda prome odgovarale klinikkoj slici kontaktnot皮炎。Pacijentkinja je negirala的研究表明，在皮肤病学的研究中，皮肤病学的研究表明:Sprovedeno je alergološko testiranje epikutanim testom na kontaktne standard alergene iz Evropske standard serije alergena (Chemotechnique Diagnostics, Vellinge，瑞典)。Utvrđen je ekcemski tip reagovanja (eritem, vezikule, otok) na benzokain。[1]〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕〔1〕Utvrđeno je da se u sastavu tog krema nalazio benzokain。Po prestanku upotrebe navedenog krema, uz kratkotrajnu primenu kortikosteroidnog krema(甲基强的松酸0.1%)promene suse povukle。Na - control - obavljenoj - 1 - 1 - 1 - 3 - 1 - 2 - 1 - 2 - 1 - 2 - 1 - 2 - 1 - 2 - 1 - 2 - 1 - 2 - 2 - 1Diskusija。扎兹利库食品制药厂，kozmetikki制药厂，kozmetikka制药厂，kozmetikka制药厂，kozmetikka制药厂，kozmetikka制药厂，kostavu sadrže苯并卡因。pore navedenog, benzokain se nalazi i u tabletama proprop kašlja, a takođe a plplikuju u vidu spreja za vreme牙科程序(ukoliko se može izbeći davanje parenteralnog lokalnog anestetika)。Neželjene reakcije (nealergijske) na sistemski primenjene lokalne anestetike su este。美国国家公共广播电台(npr)。Mepivakain, mupivakin, lidokain, prilkain) bolje se podnose dok veći broj neželjenih efekata izaziva estarska grupa anestetika (npr。苯丙氨酸，丙氨酸，四氯丙氨酸，氯丙氨酸)。Benzokain je poznat kao kontaktni过敏原koji izaziva najveći broj pozitivnih epikutanih reakcija i为kod pacijenata koji pripriom和pokazuju reaktivnost是一种中间的过敏原，ali ni na ostale pripadnike组estarskih anestetika。苯并卡因može unakrsno reagovati是一种药物，苯并卡因麻醉koji prestavljaju衍生物苯并eve kiseline (lokalni i parenteralni pripravci) i parabenima。Parabeni preprestavljaju alkal -estarske衍生物parhidroksibenzoeve kiseline, koji se <e:1> esto koriste kao konzervansi u kozmetikoj industriji。Unakrsno reagovanje par
{"title":"Perianal Allergic Contact Dermatitis from Benzocaine – a Case Report","authors":"Malena Gergovska, K. Semkova, J. Kazandjieva, N. Tsankov","doi":"10.2478/sjdv-2013-0016","DOIUrl":"https://doi.org/10.2478/sjdv-2013-0016","url":null,"abstract":"Abstract A large number of contact allergic reactions to benzocaine have been reported since its introduction to the pharmaceutical market as an active ingredient in different over-the-counter anesthetic ointments. Benzocaine is used as a key ingredient in many pharmaceuticals, such as products for oral ulcers, wound and burn preparations, sunburn remedies, hemorrhoidal preparations, oral and gingival products, sore throat sprays/lozenges, callous and wart remedies, creams for treatment of poison ivy dermatitis, tooth ache and denture irritation products. We present a 56-year-old Caucasian male with chronic rash, accompanied by intense itching in the perianal area. The lesions occurred two months earlier and the patient was treated with a wide range of topical antifungals, antibiotics and corticosteroids, with temporary improvement. The skin lesions were consistent with chronic allergic contact dermatitis. The patient denied using any topical preparations other than those prescribed by his dermatologist. Patch testing with the European baseline series was performed. A strongly positive reaction to benzocaine was identified on reading days 2 and 3. Targeted history showed intermittent use of benzocaine anti-hemorrhoidal cream to treat concomitant hemorrhoids. Benzocaine was discontinued and treatment with methylprednisolone aceponate 0.1% was initiated, resulting in significant improvement. No relapse was observed at 3-month follow-up. In conclusion, patients with confirmed benzocaine allergy should pay special attention to product labels and avoid products that contain benzocaine and its related substances. All products labelled as “anaesthetic” or “caine” should be suspected of containing benzocaine or related compounds. Patient education and awareness are critical to avoid further episodes and relapses. Sažetak Uvod. U svetskoj stručnoj literaturi opisan je veliki broj slučajeva kontaktne senzibilizacije izazvane lokalnom upotrebom benzokaina. Ovo se može objasniti velikim brojem lokalnih farmaceutika prisutnih na farmaceutskom tržištu koji se bez lekarskog recepta mogu nabaviti, a koji u svom sastavu sadrže lokalni anestetik. Benzokain predstavlja ključnu aktivnu supstanciju u mnogim preparatima koji se koriste za lečenje oralnih ulceracija, promena na desnima, bolnih upala zuba i grla, opekotina, rana, hemoroida. Nalazi se u velikom broju preparata za ispiranje usta, ali i lokalnih pripravka za lečenje kalusa i klavusa. Prikaz slučaja. Prikazujemo 56 godina staru pacijentkinju čija je glavna tegoba bila intenzivan svrab u perianalnom predelu. Dva meseca pre pregleda kod nas, pored osećaja svraba, na koži perianalne regije pojavilo se intenzivno crvenilo. U tom vremenskom periodu, u terapiju je uvođen veći broj različitih preparata za lokalno lečenje: antimikotici, antibiotici, kortikosteroidi. Poboljšanje je bilo privremeno, tako da su u momentu pregleda promene odgovarale kliničkoj slici kontaktnog dermatitisa. Pacijentkinja je negirala upot","PeriodicalId":302906,"journal":{"name":"Serbian Journal of Dermatology and Venerology","volume":"303 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121323418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Stojanović, N. Vuckovic, P. Jeremić, Biljana Jeremić
Abstract The authors present a case of a patient with extramammary Paget’s disease in the pubic region treated by a dermatologist with a private practice for almost 4 years before incisional biopsy was performed. A thorough examination showed no evidence of malignancies of internal organs, whereas definite diagnosis was made by excision of the entire skin lesion and histopathological analysis. With regard to multiple criteria, findings in our patient were consistent with current literature data, but interestingly, the primary extramammary Paget’s disease has not spread into deeper tissues. Sažetak Autori prikazuju slučaj bolesnice sa ekstramamarnom Padžetovom bolesti u pubičnoj regiji koja je lečena kod dermatologa u privatnoj praksi skoro dve godine pre incizione biopsije promene. Detaljnom pretragom nije utvrđeno istovremeno prisustvo maligniteta unutrašnjih organa, a definitivna dijagnoza je postavljena ekscizijom kožne promene u celosti i odgovarajućom patohistološkom analizom. Po mnogim kriterijumima naša bolesnica odgovara navodima u savremenoj literaturi, ali je u ovom slučaju bilo zanimljivo to da nije došlo do širenja neoplazme sa mesta primarnog ekstramamarnog M. Padžet u dubinu tkiva.
{"title":"Extramammary Paget’s Disease in the Pubic Region: a Case Report","authors":"S. Stojanović, N. Vuckovic, P. Jeremić, Biljana Jeremić","doi":"10.2478/sjdv-2013-0014","DOIUrl":"https://doi.org/10.2478/sjdv-2013-0014","url":null,"abstract":"Abstract The authors present a case of a patient with extramammary Paget’s disease in the pubic region treated by a dermatologist with a private practice for almost 4 years before incisional biopsy was performed. A thorough examination showed no evidence of malignancies of internal organs, whereas definite diagnosis was made by excision of the entire skin lesion and histopathological analysis. With regard to multiple criteria, findings in our patient were consistent with current literature data, but interestingly, the primary extramammary Paget’s disease has not spread into deeper tissues. Sažetak Autori prikazuju slučaj bolesnice sa ekstramamarnom Padžetovom bolesti u pubičnoj regiji koja je lečena kod dermatologa u privatnoj praksi skoro dve godine pre incizione biopsije promene. Detaljnom pretragom nije utvrđeno istovremeno prisustvo maligniteta unutrašnjih organa, a definitivna dijagnoza je postavljena ekscizijom kožne promene u celosti i odgovarajućom patohistološkom analizom. Po mnogim kriterijumima naša bolesnica odgovara navodima u savremenoj literaturi, ali je u ovom slučaju bilo zanimljivo to da nije došlo do širenja neoplazme sa mesta primarnog ekstramamarnog M. Padžet u dubinu tkiva.","PeriodicalId":302906,"journal":{"name":"Serbian Journal of Dermatology and Venerology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129938953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Cheilitis is an inflammatory condition of the vermilion border of the lips, which is the junction between the skin and the mucosa. Cheilitis may arise as a primary disorder of the vermilion zone; the inflammation may extend from the nearby skin, or less often from the oral mucosa. Primary cheilitis lesions are either superficial or deep. Deep types include cheilitis glandularis (inflammatory changes and lip gland swelling), and granulomatous cheilitis (chronic swelling of the lip due to granulomatous inflammation mostly of unknown origin). Cheilitis glandularis is a rare condition that mostly affects the lower lip and it is characterized by nodular enlargement, reduced mobility and lip erosion. Based on clinical presentation, cheilitis glandularis may be classified into three subtypes: simplex (described as Puente and Acevedo), superficial suppurative (described by Baelz-Unna), and the most severe type - deep suppurative, also known as cheilitis glandularis apostematosa (Volkmann’s cheilitis) characterized by deep-seated inflammation forming abscesses and fistulous tracts. This is a case report of a female patient with a deep suppurative type of cheilitis affecting both lips. Treatment with systemic antibiotics (using antibiogram tests), corticosteroids and topical therapy resulted in significant improvement. Sažetak Heilitis (Cheilitis) inflamatorno je oboljenje rumene zone usana (vermiliona) koja se nalazi na prelazu kože u sluzokožu. Heilitisi koji nastaju kao samostalna oboljenja mogu biti površni ili duboki. Duboki su Cheilitis glandularis i Cheilitis granulomatosa. Cheilitis glandularis (CG) retka je bolest koja najčešće zahvata donju usnu i karakteriše je nodularno uvećanje, redukovani mobilitet i everzija usne. Kliničke varijante su CG simplex (Puente and Acevedo), CG suppurativa superficiallis (Baelz-Unna) i CG suppurativa profunda seu CG apostematosa (Von Volkmann). Mi prikazujemo bolesnicu sa dubokom supurativnom formom heilitisa na obema usnama, kod koje je sistemska primena antibiotika, prema antibiogramu, i kortikosteroida, uz lokalnu terapiju, dovela do znatnog poboljšanja.
摘要唇炎是唇朱红色边界的一种炎症，唇朱红色边界是皮肤和粘膜之间的交界处。唇部炎可作为朱红色区原发性疾病出现;炎症可以从附近的皮肤延伸，或者很少从口腔粘膜延伸。原发性唇炎病变可为浅表或深部。深层类型包括腺性唇炎(炎症改变和唇腺肿胀)和肉芽肿性唇炎(肉芽肿性炎症引起的唇慢性肿胀，主要原因不明)。腺性唇炎是一种罕见的疾病，主要影响下唇，其特征是结节增大，活动能力降低和唇糜烂。根据临床表现，腺唇炎可分为三个亚型:单纯性(Puente和Acevedo)、浅表化脓性(Baelz-Unna)和最严重的深度化脓性(Volkmann氏)，其特征是深部炎症形成脓肿和瘘管。这是一个病例报告的女性患者深化脓性唇炎影响双唇。全身性抗生素治疗(使用抗生素谱试验)、皮质类固醇和局部治疗显著改善。Sažetak黑炎(Cheilitis)炎性炎(Heilitis inflamatorno je oboljenje瘤胃区usana(朱砂)koja se nalazi na prelazu kože u sluzokožu。黑利提斯koji nastaju kao samostalna oboljenja mogu biti površni ili duboki。腺性溃疡性溃疡性肉芽肿性溃疡。腺疱疮(CG) retka je bolest koja najčešće zahvata donju usnu i karakteriše je nodarno uvećanje, redukovani mobilitet i everzija usne。klini可分为单纯性CG (Puente and Acevedo)、浅表性CG化脓性CG (Baelz-Unna)、深度性CG化脓性CG (Von Volkmann)。Mi prikazujemo bolesnicu sa dubokom化脓性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿，原结核性脓肿poboljšanja。
{"title":"Cheilitis Glandularis Apostematosa in a Female Patient – a Case Report","authors":"M. Paravina","doi":"10.2478/sjdv-2013-0015","DOIUrl":"https://doi.org/10.2478/sjdv-2013-0015","url":null,"abstract":"Abstract Cheilitis is an inflammatory condition of the vermilion border of the lips, which is the junction between the skin and the mucosa. Cheilitis may arise as a primary disorder of the vermilion zone; the inflammation may extend from the nearby skin, or less often from the oral mucosa. Primary cheilitis lesions are either superficial or deep. Deep types include cheilitis glandularis (inflammatory changes and lip gland swelling), and granulomatous cheilitis (chronic swelling of the lip due to granulomatous inflammation mostly of unknown origin). Cheilitis glandularis is a rare condition that mostly affects the lower lip and it is characterized by nodular enlargement, reduced mobility and lip erosion. Based on clinical presentation, cheilitis glandularis may be classified into three subtypes: simplex (described as Puente and Acevedo), superficial suppurative (described by Baelz-Unna), and the most severe type - deep suppurative, also known as cheilitis glandularis apostematosa (Volkmann’s cheilitis) characterized by deep-seated inflammation forming abscesses and fistulous tracts. This is a case report of a female patient with a deep suppurative type of cheilitis affecting both lips. Treatment with systemic antibiotics (using antibiogram tests), corticosteroids and topical therapy resulted in significant improvement. Sažetak Heilitis (Cheilitis) inflamatorno je oboljenje rumene zone usana (vermiliona) koja se nalazi na prelazu kože u sluzokožu. Heilitisi koji nastaju kao samostalna oboljenja mogu biti površni ili duboki. Duboki su Cheilitis glandularis i Cheilitis granulomatosa. Cheilitis glandularis (CG) retka je bolest koja najčešće zahvata donju usnu i karakteriše je nodularno uvećanje, redukovani mobilitet i everzija usne. Kliničke varijante su CG simplex (Puente and Acevedo), CG suppurativa superficiallis (Baelz-Unna) i CG suppurativa profunda seu CG apostematosa (Von Volkmann). Mi prikazujemo bolesnicu sa dubokom supurativnom formom heilitisa na obema usnama, kod koje je sistemska primena antibiotika, prema antibiogramu, i kortikosteroida, uz lokalnu terapiju, dovela do znatnog poboljšanja.","PeriodicalId":302906,"journal":{"name":"Serbian Journal of Dermatology and Venerology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115386861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abstract Artificial penile nodules are inert objects inserted beneath the skin of the penis. Objects placed underneath the skin of the penile shaft may include plastic beads made from toothbrushes, silicon, metal pellets, glass, ivory, precious metals, marbles or pearls. The penile bead implantation is performed largely due to the belief that it will enhance sexual performance and pleasure of female or male sexual partners during intercourse. In this article, three cases with artificial penile nodules made of toothbrushes and dice are presented. All three men have implanted foreign bodies underneath the dorsal aspect of the penile skin during their prison stay and implantations were not followed by any side effects. However, insertion of foreign bodies may be followed by early and late complications and transmission of blood-borne viruses. Penile implants are important for dermatological consideration, because they make condom use more difficult and may represent a risk factor for sexually transmitted infections. Sažetak Uvod: Arteficijelni penisni nodusi su inertni objekti koji se postavljaju ispod kože penisa u cilju povećanja seksualnog zadovoljstva kako osobe koja ih je implantirala, tako i njenih budućih seksualnih partnera. Objekti koji se postavljaju pod kožu su obično od plastike, silikona, metalnih loptica, stakla, drveta, mermera ili dragocenih metala. Prikaz sučaja: U radu su prikazana tri pacijenta koji su tokom boravka u zatvoru pod kožu dorzalne strane penisa sami implantirali strana tela koja su napravili od plastike držača četkica za zube i od kockice za jamb. Proces implantacije je prošao bez neželjenih efekata. Diskusija: Iako ni u jednom od tri prikazana slučaja nije bilo neželjenih efekata, poznato je da se posle intervencija ove vrste mogu razviti rane i kasne komplikacije. Takođe je poznato na osnovu sluačjeva objavljenih u svetskoj literaturi, da postoji povišeni rizik za prenošenje virusa hepatitisa i HIV-a tokom ove prakse. Pacijente prikazujemo sa ciljem da dermatovenerologe upoznamo sa ovom praksom koja je sve više prisutna i u našoj sredini, kao i sa problemima koje ona nosi, kao što je, između ostalog, otežana upotreba kondoma tokom seksualnih odnosa, što vlasnike implantata dovodi u povećani rizik za polno prenosive infekcije. Zaključak: Na osnovu podataka iz nama dostupne literature, tri slučaja opisana u ovom radu predstavljaju prve slučajeve arteficijalnih penisnih implantata u Srbiji
人工阴茎结节是插入阴茎皮下的惰性物体。放置在阴茎皮下面的物体可能包括由牙刷、硅、金属颗粒、玻璃、象牙、贵金属、大理石或珍珠制成的塑料珠。阴茎头植入主要是由于相信它会提高性表现和性交过程中女性或男性性伴侣的快感。本文报道用牙刷和骰子制作的人工阴茎结节3例。这三名男子在监狱期间都在阴茎皮肤背面植入了异物，而且植入后没有任何副作用。然而，异物的插入可能会引起早期和晚期的并发症和血源性病毒的传播。阴茎植入物对皮肤病学的考虑很重要，因为它们使避孕套的使用更加困难，并且可能代表性传播感染的风险因素。Sažetak Uvod: artificijelni penisni nodusi su intertni objekti koji se postavljaju ispod kože penisa u cilju povećanja seksualnog zadovoljstva kako osobe koja ih je implantirala, tako i njenih budućih seksualnih partnera。Objekti koji se postavljaju pod kožu su obi no od plastike, silkona, metalnilotictica, stakla, driveta, mermera, dragocenh metali。Prikaz suaja: U radu su prikazana tri pacijenta koji su tokom boravka U zatvoru pod kožu dorzalne strane penisa sami implantirali strana tela koja su napravili od plastilike držača etkica za zube i od kockice za jamb。过程植入je prošao bez neželjenih efekata。Diskusija: Iako ni u jednom od tri priprikazana sluaja nije bilo neželjenih efekata, poznato je da se可能干预vrste mogu razviti rani i kasne komplikacije。Takođe je pozik na osnovu slua jjeva objavljenih u svetskoj文献，da postoji povišeni rizik za prenošenje病毒肝炎i HIV-a - tokom / prakse。Pacijente prikazujemo sa ciljem da dermatology upoznamo sa ovom praksom koja je sve više prisutna i u našoj sredini, kao što je, između ostalog, otežana upotreba kondoma tokom seksualnih odnosa， što vlasnike implantata dovodi u povećani rizik za polno presive infekcije。zakljuak: Na osnovu podataka iz nama dostupne literature, tri sluja opisana u ovom radu preprestavljaju prve slu ajeve arfifiicijalnih penisnih inplantata u Srbiji
{"title":"Artificial Penile Nodules: a Case Series of Three Patients","authors":"M. Bjekić","doi":"10.2478/sjdv-2013-0013","DOIUrl":"https://doi.org/10.2478/sjdv-2013-0013","url":null,"abstract":"Abstract Artificial penile nodules are inert objects inserted beneath the skin of the penis. Objects placed underneath the skin of the penile shaft may include plastic beads made from toothbrushes, silicon, metal pellets, glass, ivory, precious metals, marbles or pearls. The penile bead implantation is performed largely due to the belief that it will enhance sexual performance and pleasure of female or male sexual partners during intercourse. In this article, three cases with artificial penile nodules made of toothbrushes and dice are presented. All three men have implanted foreign bodies underneath the dorsal aspect of the penile skin during their prison stay and implantations were not followed by any side effects. However, insertion of foreign bodies may be followed by early and late complications and transmission of blood-borne viruses. Penile implants are important for dermatological consideration, because they make condom use more difficult and may represent a risk factor for sexually transmitted infections. Sažetak Uvod: Arteficijelni penisni nodusi su inertni objekti koji se postavljaju ispod kože penisa u cilju povećanja seksualnog zadovoljstva kako osobe koja ih je implantirala, tako i njenih budućih seksualnih partnera. Objekti koji se postavljaju pod kožu su obično od plastike, silikona, metalnih loptica, stakla, drveta, mermera ili dragocenih metala. Prikaz sučaja: U radu su prikazana tri pacijenta koji su tokom boravka u zatvoru pod kožu dorzalne strane penisa sami implantirali strana tela koja su napravili od plastike držača četkica za zube i od kockice za jamb. Proces implantacije je prošao bez neželjenih efekata. Diskusija: Iako ni u jednom od tri prikazana slučaja nije bilo neželjenih efekata, poznato je da se posle intervencija ove vrste mogu razviti rane i kasne komplikacije. Takođe je poznato na osnovu sluačjeva objavljenih u svetskoj literaturi, da postoji povišeni rizik za prenošenje virusa hepatitisa i HIV-a tokom ove prakse. Pacijente prikazujemo sa ciljem da dermatovenerologe upoznamo sa ovom praksom koja je sve više prisutna i u našoj sredini, kao i sa problemima koje ona nosi, kao što je, između ostalog, otežana upotreba kondoma tokom seksualnih odnosa, što vlasnike implantata dovodi u povećani rizik za polno prenosive infekcije. Zaključak: Na osnovu podataka iz nama dostupne literature, tri slučaja opisana u ovom radu predstavljaju prve slučajeve arteficijalnih penisnih implantata u Srbiji","PeriodicalId":302906,"journal":{"name":"Serbian Journal of Dermatology and Venerology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115324853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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