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Aflatoxins - Occurrence, Detoxification, Determination and Health Risks最新文献

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The Role of Socio-Economic Factors and Indigenous Knowledge Practices on the Mycotoxigenic Fungi Contamination of Food 社会经济因素和本土知识实践对食品中产霉菌毒素真菌污染的作用
Pub Date : 2022-02-09 DOI: 10.5772/intechopen.95954
Esiegbuya Daniel Ofeoritse, Ojieabu Amarachi
Indigenous methods of food processing in Nigeria are influenced by a wide range of socioeconomic factors and indigenous knowledge practices which support mycotoxingenic fungal contamination of processed food. Some of the socioeconomic factors include level of education, methods of skill acquisition, methods of food vending in market places, methods of food handling and storage, hygienic practices and poor water supply. The uses of indigenous knowledge in food processing are important because its application serve as a source of livelihood improvements, sustainability of indigenous food and eradication of food shortage. The limitation of the application of indigenous knowledge in food processing encourages mycotoxins contamination of foods. This is as a result of the poor hygienic conditions of the processing utensils, processing environments and methods of packaging the processed food. Due to the absence of policies in monitoring the quality of indigenously processed foods in market places and the risk associated with indigenous methods of food processing, there is the need for government agencies to address these issues through policy assessment in the areas of operations, inspection and enforcement and training so as to effectively harness the benefits of indigenous knowledge in food processing for national development.
尼日利亚的土著食品加工方法受到广泛的社会经济因素和土著知识实践的影响,这些因素和实践支持加工食品受到真菌毒素污染。一些社会经济因素包括教育水平、获得技能的方法、在市场上出售食物的方法、处理和储存食物的方法、卫生习惯和供水不良。在食品加工中利用土著知识是很重要的,因为它的应用可以作为改善生计、土著粮食的可持续性和消除粮食短缺的来源。本土知识在食品加工中的应用受到限制,助长了真菌毒素污染食品。这是由于加工工具、加工环境和加工食品包装方法的卫生条件差。由于缺乏监测市场上土著加工食品质量的政策,以及与土著食品加工方法有关的风险,政府机构需要通过在业务、检查和执法以及培训领域的政策评估来解决这些问题,以便有效利用土著知识在食品加工方面的好处,促进国家发展。
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引用次数: 0
Aflatoxins 黄曲霉毒素
Pub Date : 2022-02-09 DOI: 10.5772/intechopen.97292
Nadeem A. Ramadan, Hadeel A. Al-Ameri
The aflatoxin producing fungi Aspergillus flavus, A. parasiticus, and A. nomius, although they are also produced by other species of Aspergillus as well as by Emericella spp.(Telemorph). There are many types of aflatoxins, but the four main ones are aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin G1 (AFG1), and aflatoxin G2 (AFG2, while aflatoxin M1 (AFM1) and M2 (AFM2) are the hydroxylated metabolites of AFB1 and AFB2. Aflatoxin B1, which is a genotoxic hepatocarcinogen, which presumptively causes cancer by inducing DNA, adducts leading to genetic changes in target liver cells. Cytochrome-P450 enzymes to the reactive intermediate AFB1–8, 9 epoxide (AFBO) which binds to liver cell DNA, resulting in DNA adducts, metabolize AFB1 Ingestion of contaminated food is the main source of exposure to aflatoxins, which adversely affect the health of both humans and animals. The compounds can cause acute or chronic toxic effects of a teratogenic, mutagenic, carcinogenic, immunotoxic or hepatotoxic character. You can reduce your aflatoxin exposure by buying only major commercial brands of food and by discarding that look moldy, discolored, or shriveled.
黄曲霉产生黄曲霉毒素的真菌黄曲霉、寄生曲霉和野曲霉,尽管它们也由其他种类的曲霉和Emericella (Telemorph)产生黄曲霉毒素的种类很多,但主要有黄曲霉毒素B1 (AFB1)、黄曲霉毒素B2 (AFB2)、黄曲霉毒素G1 (AFG1)和黄曲霉毒素G2 (AFG2)四种,而黄曲霉毒素M1 (AFM1)和M2 (AFM2)是AFB1和AFB2的羟基化代谢产物。黄曲霉毒素B1是一种遗传毒性的肝癌原,据推测是通过诱导DNA致癌的,它加合物会导致靶肝细胞的遗传变化。细胞色素- p450酶与活性中间体AFB1 - 8,9环氧化物(AFBO)结合,与肝细胞DNA结合,产生DNA加合物,代谢AFB1。摄入受污染的食物是黄曲霉毒素暴露的主要来源,对人类和动物的健康都有不利影响。这些化合物可引起致畸、致突变、致癌、免疫毒性或肝毒性的急性或慢性毒性作用。你可以通过只购买主要商业品牌的食品和丢弃那些看起来发霉、变色或枯萎的食品来减少黄曲霉毒素的接触。
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引用次数: 0
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Aflatoxins - Occurrence, Detoxification, Determination and Health Risks
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