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Liver Trauma: Review of Management, and Patient Outcomes at Our Major Trauma Centre 肝损伤:回顾在我们的主要创伤中心的管理,和病人的结果
Pub Date : 2022-12-31 DOI: 10.36959/879/385
RW Laing, M. Edwards, T. Faulkner, K. Roberts
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引用次数: 0
Hepatocellular Carcinoma Recurrence with Metachronous Peritoneal Metastasis - A Controversial Surgical Indication 肝细胞癌复发伴异时性腹膜转移-一个有争议的手术指征
Pub Date : 2021-12-31 DOI: 10.36959/879/381
Simões João, Amaral Maria João, Serôdio Marco, Tralhão José Guilherme
Intraperitoneal metastases of a non-ruptured HCC are rare. Metastatic disease is an expression of an advanced disease, is associated with poor prognosis and can occur at the time of hepatic recurrence. We present the case of a female patient who underwent surgery for a big hepatic adenoma that suffered malignant transformation. Fifteen months later, she had HCC liver recurrence with peritoneal metastases, being submitted to a new surgery with complete resection of the hepatic mass and peritoneal implants. In the absence of HCC rupture, peritoneal dissemination is not common. Aggressive surgical treatment and adjuvant treatment with sorafenib could prolong patients’ overall survival but there is still no standard management for these patients.
未破裂HCC的腹腔内转移是罕见的。转移性疾病是一种晚期疾病的表现,与预后不良相关,可在肝脏复发时发生。我们提出的情况下,一位女性患者接受手术大肝腺瘤,遭受恶性转化。15个月后,她肝癌复发并腹膜转移,接受新的手术,完全切除肝脏肿块和腹膜植入物。在没有肝细胞癌破裂的情况下,腹膜播散并不常见。积极的手术治疗和索拉非尼辅助治疗可以延长患者的总生存期,但对于这些患者仍然没有标准的管理。
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引用次数: 0
Intrahepatic Pancreatic Pseudocysts: A Review of Recent Literature and Case Report 肝内胰腺假性囊肿:近期文献综述及病例报告
Pub Date : 2021-12-31 DOI: 10.36959/879/382
Reed-Embleton Hamish, Paraicz Tamas, Mukherjee Arijit
Background: Intrahepatic pancreatic pseudocysts (IHPP) are a rare clinical entity which results from migration of amylase rich proteolytic pancreatic fluid along hepatogastric or hepatoduodenal ligaments into the hepatic parenchyma. There are no current management guidelines, and definitive management depends on varying features within each individual case. We report a rare case presenting with features of acute gastric outlet obstruction on a background of chronic pancreatitis. The rapid formation of this IHPP does not appear to have been previously reported in the literature. Methods: We conducted a comprehensive literature search of both PubMed and the Cochrane library to identify cases of IHPPs in recent literature. This review article aims at comparing the clinical features and management of the reported case with those reported in world literature. Results: Diagnosis and clinical management of IHPP is challenging. A combination of CT scanning and aspirate sampling are the most useful in establishing a diagnosis. Clinical management includes a conservative approach, percutaneous/ endoscopic drainage, ERCP and pancreatic duct stenting. Open surgical management is reserved for cases where serious complications have occurred. Conclusion: This is the first documented rapid formation of an IHPP in current literature. The most common approach for the management of IHPPs is through radiologically guided percutaneous drainage. Early diagnosis and successful definitive management are probably best determined by the size of the lesion and severity of the clinical presentation.
背景:肝内胰腺假性囊肿(IHPP)是一种罕见的临床疾病,是由富含淀粉酶的蛋白水解胰液沿肝胃或肝十二指肠韧带迁移到肝实质所引起的。目前没有管理指南,最终的管理取决于每个病例的不同特征。我们报告一个罕见的病例,在慢性胰腺炎的背景下表现为急性胃出口梗阻。这种IHPP的快速形成在以前的文献中似乎没有报道过。方法:我们对PubMed和Cochrane图书馆进行了全面的文献检索,以确定近期文献中的IHPPs病例。这篇综述文章旨在比较报告病例的临床特点和处理与世界文献报道。结果:IHPP的诊断和临床管理具有挑战性。结合CT扫描和抽吸取样是建立诊断最有用的。临床治疗包括保守入路、经皮/内镜引流、ERCP和胰管支架置入术。开放手术是保留的情况下,严重的并发症已经发生。结论:这是目前文献中首次记录的快速形成IHPP。治疗IHPPs最常见的方法是放射学引导下的经皮引流。早期诊断和成功的最终治疗可能最好取决于病变的大小和临床表现的严重程度。
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引用次数: 0
What Shall We Do Now? Report of Unexpected CT Finding and Its Management 我们现在该怎么办?意外CT发现及其处理报告
Pub Date : 2019-06-24 DOI: 10.36959/879/375
G. Capolupo, G. Mascianá, M. Caricato
A 41 years old patient underwent total colectomy and ileal pouch-anal anastomosis with derivative ileostomy for a familiar adenomatous polyposis coli in June 2008. Pathologic examination of the specimen showed a pT1 N1 adenocarcinoma of the rectum. The patient underwent chemo-radiation and subsequent adjuvant chemotherapy. A stenosis of the pouch-anal anastomosis developed. The patient underwent several endoscopic dilations. The ileostomy was taken down in March 2016. A recurrence of the stenosis and a peri-anastomotic collection were observed. An endoscopic drainage of the collection was performed on October 3rd, 2016.
一例41岁的患者于2008年6月因常见的腺瘤性大肠息肉病行全结肠切除术和回肠袋-肛门吻合术并衍生回肠造口术。病理检查显示为直肠pT1 N1腺癌。患者接受了放化疗和随后的辅助化疗。袋-肛门吻合处出现狭窄。病人接受了几次内镜扩张。回肠造口术于2016年3月完成。观察到狭窄复发和吻合口周围收集。于2016年10月3日对收集物进行内镜引流。
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引用次数: 0
What is the Short-Term Effect of a Dose of Antibiotics on Gut Microbiota in Thyroid Cancer Patients After Surgery? An Observational Clinical Study 一定剂量抗生素对甲状腺癌术后患者肠道菌群的短期影响是什么?观察性临床研究
Pub Date : 2019-06-24 DOI: 10.36959/879/376
Zengwu Yao, Yanbing Zhou, Jiang Lixin, Zhang Yifei, Jinchen Hu, Zhiliang Wei, S. Teng, Li Yi, Xiaojie Wang, Z. Dawei, Huiyuan Zhai, Wang Dong, Zhenbin Zhang, Miaomiao Li, Menglai Zhang
International guidelines do not recommend routine systemic antibiotic prophylaxis in thyroidectomy patients as post-operative wound infections are rare, though many surgeons prefer to give preoperative antibiotics. However, the molecular-based short-term consequences of one dose of antibiotics on the human intestinal microbiota are rarely explored.
国际指南不推荐甲状腺切除术患者常规全身抗生素预防,因为术后伤口感染很少见,尽管许多外科医生倾向于术前使用抗生素。然而,一剂抗生素对人类肠道微生物群的分子基础短期后果很少被探索。
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引用次数: 0
Common Bile Duct Elongation and Obstruction Secondary to Duodenal Intussusception and Ampullary Adenoma in a Patient with Pancreas Divisum 胰分裂患者继发于十二指肠肠套叠及壶腹腺瘤的胆总管延长及梗阻
Pub Date : 2019-04-04 DOI: 10.36959/879/374
Dardon Arturo Torices, F SaldingerPierre, D. Anthony
Small bowel intussusception is an uncommon condition with cases of duodenoduodenal intussusception. (DDI) being exceptionally rare. DDI is very unusual due to the fixed position of the duodenum within the retroperitoneum. In this case, the presence of an ampullary mass caused DDI with sub mucosal elongation of the common bile duct and obstructive jaundice in a patient with pancreas divisum. Methods
小肠肠套叠是一种罕见的疾病,以十二指肠肠套叠为主。(DDI)异常罕见。由于十二指肠位于腹膜后的固定位置,DDI非常罕见。在这个病例中,壶腹肿块的存在导致DDI伴有胆总管粘膜下延伸和梗阻性黄疸的胰腺分裂患者。方法
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引用次数: 0
Pancreatic Cancer and its Treatment 胰腺癌及其治疗
Pub Date : 2018-11-22 DOI: 10.36959/879/373
Manu Mitra
Cancer begins when cells in the body start to grow out of control. As a matter of fact, cells in nearly any part of the body can become cancer and can spread to other parts of the body. It is very vital to know that if the cancer is an exocrine or endocrine because they have distinct risk, causes and they also have different signs and symptoms; they are diagnosed, treated different ways and have different viewpoint. The two major types of cancer in pancreas are exocrine pancreatic cancer and endocrine pancreatic tumors which are also called as neuroendocrine tumors (Figure 1) [1,2].
当体内的细胞开始生长失控时,癌症就开始了。事实上,身体几乎任何部位的细胞都可能癌变并扩散到身体的其他部位。了解癌症是外分泌的还是内分泌的非常重要因为它们有不同的风险,原因它们也有不同的症状和体征;他们的诊断、治疗方法不同,观点也不同。胰腺的两种主要癌症类型是外分泌型胰腺癌和内分泌型胰腺肿瘤,也称为神经内分泌肿瘤(图1)[1,2]。
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引用次数: 1
Is the Use of Sealing and Hemostatic Agents Justified in Hepatic Resections? Review and Meta-analysis 在肝切除术中使用密封和止血药物是否合理?回顾与荟萃分析
Pub Date : 1900-01-01 DOI: 10.36959/879/380
Robledo Andrea Boscà, Seller Ana Navío, NavasquilloTamarit Mireia, Ibáñez Javier Maupoey, Rosellón Raquel Jiménez, Orón Eva María Montalvá, Domínguez Rafael García, Mizrahi David Calatayud, Andújar Rafael López
The use of biological hemostatic and sealing agents over the edge of the liver resection has been increasing exponentially for over 30 years but without solid literature review. The aim of this study was to produce a meta-analysis including only prospective and randomized studies to know real effect using hemostatic sealants on the resection edge after elective hepatic resection, especially regarding biliary fistula and hematoma. A literature search of the Medline and EMBASE was carried out to find prospective and randomized trials related to the use of hemostatic sealant in the surface of the liver resection compared with not using products after the usual revision of hemostasis. Six studies were included involving a total of 1,002 patients in this meta-analysis. After analyzing the results, the risk of developing hematoma/abscess or biliary leak was not related to the use of sealants. Odds Ratio (OR): 1.19; 95% Confidence Interval (CI): 0.79 to 1.81; p=0.40 and OR: 1.02; 95% CI: 0.65 to 1.61; p=0.92 respectively. The use of sealants over the edge of the liver resection does not currently provide any benefit and its cost is not really justified. Andrea Boscà Robledo*, Ana Navío Seller, Mireia Navasquillo Tamarit, Javier Maupoey Ibáñez, Raquel Jiménez Rosellón, Eva María Montalvá Orón, Rafael García Domínguez, David Calatayud Mizrahi and Rafael López Andújar Hepatobiliary Pancreatic Surgery and Transplantation Unit, La Fe University and Polytechnic Hospital, Valencia, Spain
30多年来,在肝切除边缘使用生物止血和封闭剂呈指数增长,但没有可靠的文献综述。本研究的目的是进行一项荟萃分析,仅包括前瞻性和随机研究,以了解选择性肝切除术后使用止血密封剂对切除边缘的实际效果,特别是对胆道瘘和血肿的影响。我们对Medline和EMBASE进行了文献检索,以寻找在肝切除表面使用止血密封剂与在常规止血改良后不使用止血密封剂相关的前瞻性和随机试验。这项荟萃分析纳入了6项研究,共涉及1002名患者。在分析结果后,发生血肿/脓肿或胆道泄漏的风险与使用密封剂无关。优势比(OR): 1.19;95%置信区间(CI): 0.79 ~ 1.81;p=0.40, OR: 1.02;95% CI: 0.65 ~ 1.61;分别p = 0.92。在肝切除边缘使用密封剂目前没有任何好处,其成本也不合理。Andrea bosc Robledo*, Ana Navío Seller, Mireia Navasquillo Tamarit, Javier Maupoey Ibáñez, Raquel jimsamnez Rosellón, Eva María montalv Orón, Rafael García Domínguez, David Calatayud Mizrahi和Rafael López Andújar西班牙巴伦西亚拉菲大学和理工医院肝胆胰外科和移植科
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引用次数: 0
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Journal of Gastrointestinal and Hepatic Surgery
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