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ECHOVIST-200 enhanced hysterosonography: A new technique in the assessment of infertility echoist -200增强子宫超声:一种评估不孕症的新技术
Pub Date : 1900-01-01 DOI: 10.1097/01.ruq.0000198690.68996.2a
Bm Central
Tubal occlusion is one of the most common causes of infertility. Therefore, examination of tubal patency is a very important diagnostic tool. Our aim was to determine whether hystero-salpingo-contrast sonography is able to show tubal patency, whether it has any side effects and what role this technique may have in the future. Echovist- 200 hysterosalpingo-contrast sonographic examinations have been used in our service in 195 cases since 1998. We found tubal patency in 157 cases (84.4% ), and unilateral or bilateral occlusions in 34 instances (12.5% ). In four cases we could not visualize the tubes because they were too long. In the last mentioned cases we performed a laparascopy-dye test for the control of our results. The most common side effect during the check-up procedure was abdominal pain. This the patients tolerated well. We did not experience any other serious side effect. Comparing our results with those reported from abroad, we found them similar to the latter. According to our experience, the HyCoSy method for the evaluation of infertility is quick and well tolerated.
输卵管阻塞是不孕最常见的原因之一。因此,检查输卵管通畅是非常重要的诊断工具。我们的目的是确定子宫输卵管造影是否能够显示输卵管通畅,是否有任何副作用,以及这项技术在未来可能发挥的作用。自1998年以来,我们使用了Echovist- 200子宫输卵管对比超声检查195例。我们发现157例(84.4%)输卵管通畅,34例(12.5%)单侧或双侧闭塞。在四个病例中,我们无法看到输卵管,因为它们太长了。在最后提到的情况下,我们进行了腹腔镜染色试验,以控制我们的结果。检查过程中最常见的副作用是腹痛。患者对此耐受良好。我们没有遇到任何其他严重的副作用。将我们的结果与国外报道的结果进行比较,我们发现后者相似。根据我们的经验,HyCoSy方法用于不孕症的评估是快速且耐受性良好的。
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引用次数: 3
Therapy with both magnesium sulfate and nifedipine does not increase the risk of serious magnesium-related maternal side effects in women with preeclampsia 同时使用硫酸镁和硝苯地平治疗不会增加子痫前期妇女发生严重镁相关母体副作用的风险
Pub Date : 1900-01-01 DOI: 10.1097/00132582-200512000-00008
Bc Women
Objective: Does the use of nifedipine and magnesium sulfate together increase serious magnesium-related effects? Study design: This was a retrospective chart review of women who were admitted to BC Women' s Hospital and Health Centre (1997-2001) and were given intravenous magnesium sulfate for preeclampsia. Serious magnesium-related effects were compared among 162 cases who received magnesium sulfate and contemporaneous nifedipine and 215 control subjects who received magnesium sulfate and either another antihypertensive (n = 32 women) or no antihypertensive (n = 183 women) medication. Chi-squared test, Fisher' s exact test, or the Student t test was used for data comparison between cases and each control group. A probability value of .05 was considered statistically significant. Results: The cases had more severe preeclampsia and a longer magnesium sulfate infusion. However, cases had no excess of neuromuscular weakness (53.1% ) versus control subjects who received antihypertensive medication (53.1% ; P = .99) or control subjects who received no antihypertensive medication (44.8% ; P = .13) or other serious magnesium-related effects. Cases versus control subjects who received antihypertensive medication had less neuromuscular blockade (odds ratio, 0.04; 95% CI, 0.002-0.80). Cases versus control subjects who received no antihypertensive medication had less maternal hypotension (41.4% vs 53.0% ; P = .04). Conclusion: The use of nifedipine and magnesium sulfate together does not increase the risk of serious magnesium-related effects.
目的:硝苯地平与硫酸镁联合使用是否会增加严重的镁相关效应?研究设计:这是对1997-2001年BC省妇女医院和保健中心接受静脉注射硫酸镁治疗先兆子痫的妇女的回顾性图表回顾。比较了162例同时服用硫酸镁和硝苯地平的患者和215例同时服用硫酸镁和其他降压药(n = 32)或不服用降压药(n = 183)的对照组的严重镁相关效应。病例与各对照组之间的数据比较采用卡方检验、Fisher精确检验或Student t检验。概率值为0.05被认为具有统计学意义。结果:本组患者子痫前期加重,硫酸镁输注时间延长。然而,与接受抗高血压药物治疗的对照组(53.1%)相比,病例没有过度的神经肌肉无力(53.1%);P = 0.99)或未接受抗高血压药物治疗的对照组(44.8%;P = 0.13)或其他与镁有关的严重影响。与对照组相比,接受抗高血压药物治疗的患者神经肌肉阻滞较少(优势比,0.04;95% ci, 0.002-0.80)。与对照组相比,未接受抗高血压药物治疗的孕妇低血压发生率较低(41.4% vs 53.0%;P = .04)。结论:硝苯地平与硫酸镁联用不会增加严重镁相关反应的发生风险。
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引用次数: 0
Clinical features and prognostic factors in adults with bacterial meningitis 成人细菌性脑膜炎的临床特点及预后因素分析
Pub Date : 1900-01-01 DOI: 10.1056/nejm200503033520929
D. Amsterdam
BACKGROUND: We conducted a nationwide study in the Netherlands to determine cl inical features and prognostic factors in adults with community acquired acute bacterial meningitis. METHODS: From October 1998 to April 2002, all Dutch patien ts with community acquired acute bacterial meningitis, confirmed by cerebrospin al fluid cultures, were prospectively evaluated. All patients underwent a neurol ogic examination on admission and at discharge, and outcomes were classified as unfavorable (defined by a Glasgow Outcome Scale score of 1 to 4 points at discha rge) or favorable (a score of 5). Predictors of an unfavorable outcome were iden tified through logis tic regression analysis. RESULTS: We evaluated 696 episod es of community acquired acute bacterial meningitis. The most common pathogens were Streptococcus pneumoniae (51 percent of pisodes) and Neisseria meningitidis (37 percent). The classic triad of fever, neck stiffness, and a change in menta l status was present in only 44 percent of episodes; however, 95 percent had at least two of the four symptoms of headache, fever, neck stiffness, and altered m ental status. On admission, 14 percent of patients were comatose and 33 percent had focal neurologic abnormalities. The overall mortality rate was 21 percent. T he mortality rate was higher among patients with pneumococcal meningitis than am ong those with meningococcal meningitis (30 percent vs. 7 percent, P 0.001). Th e outcome was unfavorable in 34 percent of episodes. Risk factors for an unfavor able outcome were advanced age, presence of otitis or sinusitis, absence of rash, a low score on the Glasgow Coma Scale on admission , tachycardia, a positive blood culture, an elevated erythrocyte sedimentation r ate, thrombocytopenia, and a low cerebrospinal fluid white cell count. In adult s presenting with community acquired acute bacterial meningitis, the sensitivit y of the classic triad of fever, neck stiffness, and altered mental status is lo w, but almost all present with at least two of the four symptoms of headache, fe ver, neck stiffness, and altered mental status. The mortality associated with ba cterial meningitis remains high, and the strongest risk factors for an unfavorab le outcome are those that are indicative of systemic compromise, a low level of consciousness, and infection with S. pneumoniae.
背景:我们在荷兰进行了一项全国性的研究,以确定社区获得性急性细菌性脑膜炎成人的临床特征和预后因素。方法:对1998年10月至2002年4月荷兰所有经脑脊液培养证实的社区获得性急性细菌性脑膜炎患者进行前瞻性评价。所有患者在入院和出院时都进行了神经系统检查,结果分为不良(出院时格拉斯哥预后量表评分为1到4分)和良好(评分为5分)。通过逻辑回归分析确定不良结果的预测因素。结果:我们评估了696例社区获得性急性细菌性脑膜炎。最常见的病原体是肺炎链球菌(51%)和脑膜炎奈瑟菌(37%)。发烧、颈部僵硬和精神状态改变的典型三联征仅在44%的发作中出现;然而,95%的人至少有四种症状中的两种:头痛、发烧、颈部僵硬和精神状态改变。入院时,14%的患者处于昏迷状态,33%的患者有局灶性神经异常。总体死亡率为21%。肺炎球菌性脑膜炎患者的死亡率高于脑膜炎球菌性脑膜炎患者(30%对7%,P < 0.001)。在34%的事件中,结果是不利的。不利结果的危险因素为高龄、存在中耳炎或鼻窦炎、无皮疹、入院时格拉斯哥昏迷评分低、心动过速、血培养阳性、红细胞沉降率升高、血小板减少和脑脊液白细胞计数低。在以社区获得性急性细菌性脑膜炎为表现的成人中,发热、颈部僵硬和精神状态改变的典型三联征的敏感性较低,但几乎所有人都表现为头痛、发烧、颈部僵硬和精神状态改变四种症状中的至少两种。与脑膜炎相关的死亡率仍然很高,导致不利结果的最强危险因素是那些表明全身损害、意识水平低和肺炎链球菌感染的因素。
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引用次数: 40
Ultrasonography shows extensive nerve enlargements in multifocal motor neuropathy 超声检查显示多灶性运动神经病的神经广泛扩大
Pub Date : 1900-01-01 DOI: 10.1097/01.ruq.0000198684.00384.f3
Cx Heerlen
Using ultrasonography we found multiple sites with nerve enlargement along the course of the brachial plexus, median, ulnar, and radial nerves in the majority of 21 patients with multifocal motor neuropathy. Sonography and electrophysiologic studies showed more abnormalities than expected on purely clinical grounds. Moreover, sonography revealed nerve enlargement without clinical or electrophysiologic abnormalities.
我们在21例多灶性运动神经病患者中发现沿臂丛神经、正中神经、尺神经和桡神经的多处神经肿大。超声检查和电生理检查显示的异常比纯粹临床原因预期的要多。此外,超声检查显示神经肿大,无临床或电生理异常。
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引用次数: 20
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