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Frequency Of Hyperkalaemia In Non-Dialysis Dependent Chronic Kidney Disease (CKD) Patients 非透析依赖性慢性肾病(CKD)患者高钾血症的频率
Q4 Medicine Pub Date : 2023-07-14 DOI: 10.60110/230601
Abdul Qadir, Zareen Ullah, Muhammad Daud Khalil, Muhammad Najumu Saqib, Aimal Khan, Adam K Khan, Saqib Khalil MD, Khan Mn
Objective: To examine the prevalence of hyperkalaemia and its relationship with various demographic and clinical variables among non-dialysis dependent chronic kidney disease (CKD) patients. Study Design: A cross-sectional study. Place and Duration of Study: This study was conducted at the Nephrology Unit of Khyber Teaching Hospital, Peshawar, from September 6, 2020, to March 5, 2021. Materials and Methods: The study evaluated 150 diagnosed non-dialysis dependent CKD patients aged between 20 to 60 years. Demographic information, duration of CKD, and other relevant clinical data were recorded. Serum potassium levels were obtained, and renal function was quantified using the MDRD-4 equation. Serum K level >5 mmol/L was considered hyperkalaemia. Statistical analyses, Mean ± SD, univariate and multivariate logistic regression were produced using latest version 21 SPSS. Results: Patients mean age was 39 ± 11.2 years, with 53.3% being male 46.7% female. The mean duration of CKD was 10.2 ± 7.2 months, and 60% of patients had been diagnosed with CKD for less than 1 year. Hyperkalaemia was observed in 45.3% of the patients. Significant associations were found between hyperkalaemia and factors such as CKD duration (p < 0.05), CKD staging (p < 0.05), and BMI >25 kg/m² (p < 0.05).Log odds of hyperkalemia increased by 1.9598 as patients were moving from Stage 1-2 to Stage 3-4. Conclusion: This study features the high prevalence of hyperkalaemia in non-dialysis dependent CKD patients and its associations with CKD Stages, duration, and demographic characteristics. These findings emphasize the seriousness of surveying and managing serum potassium levels in these patient population to prevent potential life-threatening complications. Key Words: Hyperkalaemia, Chronic kidney disease, Nephrology, Prevalence Citation of article: Qadir A, Zareen Ullah, Khalil MD, Saqib MN, Khan A, Khan A. Frequency of Hyperkalaemia in Non-Dialysis Dependent Chronic Kidney Disease (CKD) Patients. Med Forum 2023;34(6):2-5.
目的:探讨非透析依赖型慢性肾脏疾病(CKD)患者高钾血症的患病率及其与各种人口统计学和临床变量的关系。研究设计:横断面研究。研究地点和时间:本研究于2020年9月6日至2021年3月5日在白沙瓦开伯尔教学医院肾脏病科进行。材料和方法:该研究评估了150名年龄在20至60岁之间的诊断为非透析依赖的CKD患者。记录人口学信息、CKD病程及其他相关临床数据。测定血清钾水平,用MDRD-4方程定量测定肾功能。血清钾水平>5 mmol/L为高钾血症。统计分析、Mean±SD、单因素和多因素logistic回归采用最新版本21 SPSS。结果:患者平均年龄39±11.2岁,男性占53.3%,女性占46.7%。CKD的平均持续时间为10.2±7.2个月,60%的患者被诊断为CKD少于1年。45.3%的患者出现高钾血症。高钾血症与CKD病程(p < 0.05)、CKD分期(p < 0.05)和BMI >25 kg/m²(p < 0.05)等因素之间存在显著相关性。随着患者从1-2期转移到3-4期,高钾血症的对数赔率增加了1.9598。结论:本研究的特点是非透析依赖性CKD患者高钾血症的高患病率及其与CKD分期、持续时间和人口统计学特征的关联。这些发现强调了在这些患者人群中测量和管理血清钾水平以预防潜在危及生命的并发症的严重性。关键词:高钾血症,慢性肾脏疾病,肾脏病学,患病率文章引用:Qadir A, Zareen Ullah, Khalil MD, Saqib MN, Khan A, Khan A。非透析依赖性慢性肾脏疾病(CKD)患者高钾血症的频率中国医学杂志(英文版);34(6):2-5。
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