Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4475
R. Murphy, Y. Lai, Y. Chow, D. An, W. Altemeier, S. Gharib, T. Hallstrand
{"title":"IL-18 Receptor-deficient Mice Have Enhanced Airway Hyperresponsiveness and Eosinophilia in a Model of Allergic Asthma","authors":"R. Murphy, Y. Lai, Y. Chow, D. An, W. Altemeier, S. Gharib, T. Hallstrand","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4475","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4475","url":null,"abstract":"","PeriodicalId":365221,"journal":{"name":"C13. CYTOKINES: CYTOKINES IN THE AIRWAYS","volume":"231 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134087383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4471
D. Cook, C. Thomas, A. Wu, M. Rusznak, J. Zhang, W. Zhou, J. Cephus, K. Corley-Gibson, V. Polosukhin, A. Norlander, D. Newcomb, D. Stoltz, R. Peebles
{"title":"Loss of CFTR Reprograms Airway Epithelial IL-33 Release and Regulates IL-33 Dependent Inflammation","authors":"D. Cook, C. Thomas, A. Wu, M. Rusznak, J. Zhang, W. Zhou, J. Cephus, K. Corley-Gibson, V. Polosukhin, A. Norlander, D. Newcomb, D. Stoltz, R. Peebles","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4471","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4471","url":null,"abstract":"","PeriodicalId":365221,"journal":{"name":"C13. CYTOKINES: CYTOKINES IN THE AIRWAYS","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114621876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4477
G. Necker, R. Gannon, H. Gong, A. Thurman, L. Tran, R. Tudas, G. Romano-Ibarra, B. Bettis, A. Pezzulo
{"title":"IL-13 Induces Epigenetic Inflammatory Memory in a Subset of Airway Stem Cell Clones","authors":"G. Necker, R. Gannon, H. Gong, A. Thurman, L. Tran, R. Tudas, G. Romano-Ibarra, B. Bettis, A. Pezzulo","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4477","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4477","url":null,"abstract":"","PeriodicalId":365221,"journal":{"name":"C13. CYTOKINES: CYTOKINES IN THE AIRWAYS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125820087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4472
S.-J. Kim, S. Bear, D. Dai, P. Lee
{"title":"Inhibition of Macrophage Migration Inhibitory Factor Signaling Prevents SARS-CoV-2 Infection","authors":"S.-J. Kim, S. Bear, D. Dai, P. Lee","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4472","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4472","url":null,"abstract":"","PeriodicalId":365221,"journal":{"name":"C13. CYTOKINES: CYTOKINES IN THE AIRWAYS","volume":"6 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126007292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4474
M. Tabary, H. Peñaloza, X. An, M. Kochin, W. Bain, Z. Xiong, J. Lee
{"title":"N-terminal Truncated Forms of the Cytokine IL-36γ Derived From Host Proteases Induce Airspace Neutrophil Recruitment and CXCL-5 Production in the Lung","authors":"M. Tabary, H. Peñaloza, X. An, M. Kochin, W. Bain, Z. Xiong, J. Lee","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4474","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4474","url":null,"abstract":"","PeriodicalId":365221,"journal":{"name":"C13. CYTOKINES: CYTOKINES IN THE AIRWAYS","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133166892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4478
S. Asrat, Y. Mao, Y. Zhou, V. Kamat, A. Rafique, W.-C. Chen, G. Scott, D. Birchard, L. Ben, A. Murphy, M. C. Franklin, M. Sleeman, J. Orengo
{"title":"Itepekimab Binds to IL-33 With High Affinity, Prevents the Formation of IL-33/ST2/IL-1RAcP Signaling Complex and Blocks Mediators of Airway Inflammation","authors":"S. Asrat, Y. Mao, Y. Zhou, V. Kamat, A. Rafique, W.-C. Chen, G. Scott, D. Birchard, L. Ben, A. Murphy, M. C. Franklin, M. Sleeman, J. Orengo","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4478","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4478","url":null,"abstract":"","PeriodicalId":365221,"journal":{"name":"C13. CYTOKINES: CYTOKINES IN THE AIRWAYS","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131647093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4479
J. Alladina, N. Smith, Kamil Slowikowski, T. Kooistra, R. A. Rahimi, A. Haring, N. D. Nguyen, S.L. Sheng, L. Hariri, A. Luster, A. Villani, J.L. Cho, F. Giacona, B. Medoff
{"title":"Hillock Cells Are Immunoresponsive Airway Epithelial Cells That Promote Type 2 Inflammation and Barrier Dysfunction in Asthmatics","authors":"J. Alladina, N. Smith, Kamil Slowikowski, T. Kooistra, R. A. Rahimi, A. Haring, N. D. Nguyen, S.L. Sheng, L. Hariri, A. Luster, A. Villani, J.L. Cho, F. Giacona, B. Medoff","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4479","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4479","url":null,"abstract":"","PeriodicalId":365221,"journal":{"name":"C13. CYTOKINES: CYTOKINES IN THE AIRWAYS","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116633044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4476
W. Teague, M. Lawrence, K. Boyd, K. Wavell, L. Borish
{"title":"Lung Lavage Cytokine Signatures in Preschool Children With Problematic Wheeze Infected With Rhinovirus Supports M1 and M2 Alveolar Macrophage Activation","authors":"W. Teague, M. Lawrence, K. Boyd, K. Wavell, L. Borish","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4476","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4476","url":null,"abstract":"","PeriodicalId":365221,"journal":{"name":"C13. CYTOKINES: CYTOKINES IN THE AIRWAYS","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122083916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4473
S. Srivatsan, S. Asrat, K. Nagashima, G. Scott, W. Lim, D. Birchard, L. Ben, A. Le Floch, J. Allinne, A. Murphy, M. Sleeman, J. Orengo
{"title":"Interleukin-33 (IL-33) Drives Type 1 and Type 2 Inflammation and Instructs Airway Remodeling","authors":"S. Srivatsan, S. Asrat, K. Nagashima, G. Scott, W. Lim, D. Birchard, L. Ben, A. Le Floch, J. Allinne, A. Murphy, M. Sleeman, J. Orengo","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4473","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a4473","url":null,"abstract":"","PeriodicalId":365221,"journal":{"name":"C13. CYTOKINES: CYTOKINES IN THE AIRWAYS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128272098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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