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Development of the Principles of Fuzzy Rule-Based System for Hepatocelular Carcinoma Staging 基于模糊规则的肝癌分期系统原理研究
Pub Date : 2021-05-27 DOI: 10.21303/2461-4262.2021.001829
M. Mammadova, N. Bayramov, Zarifa Jabrayilova
The article proposes the principles for the development of a fuzzy rule-based physician decision support system n to determine the stages of the most common hepatocellular carcinoma (HCC) among malignant tumors of liver. The stages of HCC, i.e., critical situations, are expressed by different combinations of clinical signs of input data and emerging clinical conditions. These combinations shape the multiplicity of possible situations (critical situations) by forming linguistic rules that are in fuzzy relations with one another. The article presents the task of developing a fuzzy rules-based system for HCC staging by classifying the set of possible situations into given classes. In order to solve the problem, fuzzy rules of clinical situations and critical situations deviated from them are developed according to the possible clinical signs of input data. The rules in accordance with the decision-making process are developed in two phases. In the first phase, three input data are developed: nine rules are developed to determine possible clinical conditions based on the number, size, and vascular invasion of tumor. In the second phase, seven rules are developed based on possible combinations of input data on the presence of lymph nodes and metastases in these nine clinical conditions. At this stage, the rules representing the fuzzification of results obtained are also described. The latter provide an interpretation of results and a decision on related stage of HCC. It also proposes a functional scheme of fuzzy rules-based system for HCC staging, and presents the working principle of structural blocks. The fuzzy rule-based system for HCC staging can be used to support physicians to make diagnostic and treatment decisions
本文提出了基于模糊规则的医师决策支持系统的开发原则,以确定肝脏恶性肿瘤中最常见的肝细胞癌(HCC)的分期。HCC的分期,即危重情况,通过输入数据的临床体征和新出现的临床情况的不同组合来表达。这些组合通过形成彼此之间存在模糊关系的语言规则,形成了可能情况(危急情况)的多样性。本文提出了一个基于模糊规则的肝癌分期系统的任务,通过将可能的情况集分类到给定的类别中。为了解决这一问题,根据输入数据可能出现的临床症状,制定了临床情况和偏离临床情况的模糊规则。与决策过程相适应的规则分为两个阶段。在第一阶段,开发3个输入数据:开发9条规则,根据肿瘤的数量、大小和血管侵犯来确定可能的临床状况。在第二阶段,根据这九种临床情况下淋巴结和转移存在的输入数据的可能组合,制定七条规则。在此阶段,还描述了表示所得到结果模糊化的规则。后者提供了对结果的解释和HCC相关分期的决定。提出了基于模糊规则的肝癌分期系统的功能方案,并给出了结构块的工作原理。基于模糊规则的HCC分期系统可用于支持医生做出诊断和治疗决策
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引用次数: 4
VOX Pop: Why Banning Energy Drinks Doesn't Make Sense VOX Pop:为什么禁止能量饮料没有意义
Pub Date : 2019-12-31 DOI: 10.2139/ssrn.3852054
C. Snowdon
The government has proposed a ban on the sale of energy drinks to minors on the basis that these products have high levels of sugar and caffeine, and can be damaging to health. Many energy drinks are low in sugar or contain no sugar at all. Even full sugar energy drinks do not contain more sugar than Pepsi. All the leading energy drink brands have 32 mg of caffeine per 100 ml. This is more than tea and cola but less than any form of caffeinated coffee. Most single-serve coffees from leading high street retailers contain more caffeine than a can of energy drink. Young people consume far more caffeine from tea, coffee and cola than they do from energy drinks. Among 10 to 17 year olds, energy drinks contribute just 10.5% of total caffeine intake. Even the heaviest adolescent consumers of energy drinks get more than 80% of their caffeine from other sources. There is no evidence that sugar and caffeine in energy drinks is more problematic than sugar and caffeine in other beverages. A ban on one category of the soft drink market would be discriminatory and disproportionate.
政府已经提议禁止向未成年人出售能量饮料,因为这些产品含有高含量的糖和咖啡因,可能会损害健康。许多能量饮料的含糖量很低,或者根本不含糖。即使是全糖能量饮料的含糖量也不会超过百事可乐。所有主要的能量饮料品牌每100毫升含有32毫克咖啡因,这比茶和可乐都要多,但比任何含咖啡因的咖啡都要少。大多数来自主要商业街零售商的单杯咖啡所含的咖啡因比一罐能量饮料还多。年轻人从茶、咖啡和可乐中摄入的咖啡因远远超过能量饮料。在10到17岁的人群中,能量饮料只占咖啡因摄入总量的10.5%。即使是饮用能量饮料最多的青少年,也有超过80%的咖啡因来自其他来源。没有证据表明能量饮料中的糖和咖啡因比其他饮料中的糖和咖啡因更有问题。对一类软饮料市场的禁令将是歧视性的和不成比例的。
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引用次数: 0
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DecisionSciRN: Decision-Making in Healthcare (Topic)
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