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American Academy of Orthopaedic Surgeon最新文献

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Hip Instability 髋关节不稳定
Pub Date : 2011-06-01 DOI: 10.5435/00124635-201204000-00003
R. Boykin, Adam W Anz, Brandon D. Bushnell, M. Kocher, Allston J Stubbs, M. Philippon
Abstract Understanding of the etiology and pathology of hip instability has increased in recent years as new information has emerged regarding the disease processes of the hip. Hip instability, heretofore considered uncommon in clinical practice, is increasingly recognized as a pathologic entity. Instability may be classified as traumatic or atraumatic, and diagnosis is made based on patient history, physical examination, and imaging studies. Plain radiography, MRI, MRI arthrography, and hip instability tests (eg, posterior impingement, dial) can be used to confirm the presence of instability. Nonsurgical management options include physical therapy and protected weight bearing. Surgical intervention, whether arthroscopic or open, is required for large acetabular fractures and refractory instability. Knowledge of the etiology and evolving research of hip instability is essential to understand the spectrum of hip disease.
近年来,随着有关髋关节疾病过程的新信息的出现,对髋关节不稳定的病因学和病理学的了解有所增加。髋关节不稳定,迄今为止在临床实践中被认为是罕见的,越来越被认为是一种病理实体。不稳定性可分为外伤性和非外伤性,诊断依据患者病史、体格检查和影像学检查。x线平片、MRI、MRI关节造影和髋关节不稳定性检查(如后侧撞击、侧盘)可用于确认不稳定性的存在。非手术治疗方案包括物理治疗和保护性负重。对于大髋臼骨折和难治性不稳定需要手术干预,无论是关节镜下还是开放手术。了解髋关节不稳定的病因学和不断发展的研究对于了解髋关节疾病的谱是必不可少的。
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引用次数: 9
On the Horizon From the ORS 从ORS看地平线
Pub Date : 2010-07-01 DOI: 10.5435/00124635-201007000-00007
S. Arnoczky, Oscar Caballero, Y. Yeni
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引用次数: 10
Antifibrinolytics in Major Orthopaedic Surgery 抗纤溶药物在骨科手术中的应用
Pub Date : 2010-03-01 DOI: 10.5435/00124635-201003000-00002
J. Eubanks
Total joint arthroplasty and deformity surgery of the spine can require complex reconstructive procedures accompanied by the potential for major blood loss. In an attempt to minimize the perioperative blood loss associated with these procedures, recent focus has concentrated on the efficacy of pharmacologic agents. Antifibrinolytics such as &egr;‐aminocaproic acid, tranexamic acid, and aprotinin have been shown to reduce perioperative blood loss, autologous blood donation, transfusions, and associated costs in cardiac as well as major orthopaedic surgery. These agents reduce perioperative blood loss by inhibition of clot breakdown. Prospective, randomized studies have shown that the use of these agents can be effective in reducing the perioperative blood loss and transfusion requirements in total joint arthroplasty, pediatric scoliosis surgery, and adult reconstructive surgery of the spine. Aprotinin, however, is currently under suspension from use pending further evaluation of a trial. Although concerns exist about increased thrombotic events with the use of these agents, large meta‐analyses suggest that antifibrinolytics can be safely and efficaciously employed to decrease perioperative blood loss and transfusion requirements.
全关节置换术和脊柱畸形手术可能需要复杂的重建过程,并伴有潜在的大量失血。为了尽量减少与这些手术相关的围手术期失血,最近的焦点集中在药物的疗效上。抗纤溶药物如egr -氨基己酸、氨甲环酸和抑酶蛋白已被证明可以减少心脏和主要骨科手术的围手术期出血量、自体献血、输血和相关费用。这些药物通过抑制凝块破裂来减少围手术期失血。前瞻性、随机研究表明,在全关节置换术、儿童脊柱侧凸手术和成人脊柱重建手术中,使用这些药物可以有效减少围手术期的失血和输血需求。然而,抑肽酶目前处于暂停使用状态,等待进一步的试验评估。尽管人们担心使用这些药物会增加血栓形成事件,但大型荟萃分析表明,抗纤溶药物可以安全有效地用于减少围手术期失血和输血需求。
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引用次数: 179
Challenges With Health‐related Quality of Life Assessment in Arthroplasty Patients: Problems and Solutions 关节置换术患者健康相关生活质量评估的挑战:问题与解决方案
Pub Date : 2010-02-01 DOI: 10.5435/00124635-201002000-00002
J. Singh, J. Sloan, N. Johanson
Assessment of health‐related quality of life (HRQOL) using patient‐reported outcomes in arthroplasty has become popular because it provides a unique perspective on successful elective procedures. However, challenges exist in the assessment of HRQOL in clinical practice and in clinical research. Patient compliance with multiple and sometimes lengthy HRQOL assessments administered at multiple follow‐up visits is problematic. Many well‐validated HRQOL instruments are available, and progress has been made in defining the minimal clinically important difference in hip and knee arthroplasty that denotes the minimal change perceived to be important by patients. Challenges in understanding the literature are attributable to the use of various HRQOL scales, with different scoring ranges and scoring algorithms, different interpretations of highest score, and differences in the presentation of raw versus transformed scores.
利用患者报告的关节置换术结果评估健康相关生活质量(HRQOL)已经变得流行,因为它为成功的选择性手术提供了独特的视角。然而,在临床实践和临床研究中,对HRQOL的评估都存在着挑战。在多次随访中对患者进行多次、有时是冗长的HRQOL评估的依从性是有问题的。许多经过验证的HRQOL仪器都是可用的,并且在定义髋关节和膝关节置换术的最小临床重要差异方面取得了进展,这表明患者认为重要的最小变化。理解文献的挑战是由于使用各种HRQOL量表,具有不同的评分范围和评分算法,对最高分的不同解释,以及原始分数与转换分数的不同表示。
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引用次数: 112
Advances in the Management of Spinal Cord Injury 脊髓损伤的治疗进展
Pub Date : 1998-09-01 DOI: 10.1097/00013414-199809000-00008
Ranjan Gupta, Mary Bathen, Jeremy S. Smith, A. Levi, N. Bhatia, O. Steward
&NA; Historically, clinical outcomes following spinal cord injury have been dismal. Over the past 20 years, the survival rate and long‐term outcome of patients with spinal cord injury have improved with advances in both medical and surgical treatment. However, the efficacy and timing of these adjuvant treatments remain controversial. There has been a tremendous increase in the number of basic science and clinical studies on spinal cord injury. Current areas of investigation include early acute management, including early surgical intervention, as well as new pharmacotherapy and cellular transplantation strategies. It is unlikely that a single approach can uniformly address all of the issues associated with spinal cord injury. Thus, a multidisciplinary approach will be needed.
患者;从历史上看,脊髓损伤后的临床结果令人沮丧。在过去的20年里,随着医学和外科治疗的进步,脊髓损伤患者的存活率和长期预后得到了改善。然而,这些辅助治疗的疗效和时机仍然存在争议。近年来,关于脊髓损伤的基础科学和临床研究的数量急剧增加。目前的研究领域包括早期急性管理,包括早期手术干预,以及新的药物治疗和细胞移植策略。单一方法不太可能统一地解决与脊髓损伤相关的所有问题。因此,需要一种多学科的方法。
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引用次数: 65
期刊
American Academy of Orthopaedic Surgeon
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