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CNS Aspergillosis 中枢神经系统曲霉病
Pub Date : 2023-03-07 DOI: 10.3329/akmmcj.v12i2.64702
Dewan Shamsul Asif, Sumiya Akther, Safwat Binte Salam, Md Mahmudur Rahman Siddiqui, Tasnim Haque Chowdhury
Cerebral aspergillosis has the tendency to occur in immune-compromised patients. Less commonly, immune-competent individuals can be affected, with neuroimaging findings being difficult to interpret. A surgical excision with aggressive antifungal therapy is required for a proper management. This case report describes an immune-competent patient with cerebral aspergillosis that presented radiologically as a suspicious mass to be diagnosed pathologically and excised surgically. AKMMC J 2021; 12(2): 107-112
脑曲霉病往往发生在免疫功能低下的患者。不太常见的是,免疫能力强的个体也会受到影响,神经影像学结果难以解释。手术切除和积极的抗真菌治疗是必要的妥善处理。本病例报告描述了一位具有免疫功能的脑曲霉病患者,其影像学表现为可疑肿块,经病理诊断并手术切除。Akmmc j 2021;12 (2): 107 - 112
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引用次数: 0
Kampung Sungai to Kerala: A deadly zoonotic trail encroaching diverse geography 甘pung Sungai到喀拉拉邦:一条致命的人畜共患病路线,侵占了不同的地理位置
Pub Date : 2023-03-05 DOI: 10.3329/akmmcj.v12i1.64630
SM Rashed Ul Islam, Munira Jahan, Md Mahmudur Rahman Siddiqui
Background: Nipah virus is an emerging zoonotic virus which causes fatal encephalitis in South-East Asia region since 1999. Thereafter, it is prevalent almost every year in the different parts of Bangladesh and India. The aims of this analysis to describe the epidemiological patterns of the Nipah infection and also to highlight the factors for the recurrent outbreak in this region. Materials & methods: Intensive web searching was done for documents and journals on Nipah Virus infection and Nipah outbreak from 1999 to 2018. A total of 279 research documents were found and about 40 papers, especially the PubMed indexed sources and newsletters distributed by different public health agencies were selected for the meta-analysis. Information gathered from the selected journals and documents were described in text and figures. Results: The analysis revealed that fruit bats of the Pteropus genus are the natural hosts of the virus. After documentation of only outbreak in Malaysia in 1999, Nipah virus struck in Meherpur in 2001 for the first time and thereby, creating a public health issue every year. Very recently, this deadly zoonotic virus caused fatality in Kerala, India which is far away from its usual prevalent region. It starts with the ingestion of Nipah infected raw date palm sap and direct contact with the infected person. Early diagnosis and strict isolation is the mainstay to prevent an outbreak. Strong public health measures can able to reduce both the frequency and mortality of the disease. Conclusions: Nipah virus infection is now one of the ten priority diseases listed by the World Health Organization considering its high fatality rate. However, effective health education and infection control practice is still considered as the mainstay of prevention of future Nipah outbreak. AKMMC J 2021; 12(1) : 52-57
背景:尼帕病毒是自1999年以来在东南亚地区引起致命性脑炎的一种新出现的人畜共患病毒。此后,它几乎每年都在孟加拉国和印度的不同地区流行。这项分析的目的是描述尼帕病毒感染的流行病学模式,并强调该地区反复暴发的因素。材料,方法:对1999 - 2018年有关尼帕病毒感染和尼帕疫情的文献和期刊进行网络检索。共检索到279篇研究文献,选取了约40篇论文进行meta分析,特别是PubMed索引来源和不同公共卫生机构分发的通讯。从选定的期刊和文献中收集的信息在文本和图中进行了描述。 结果:分析结果表明,狐蝠属果蝠是该病毒的天然宿主。尼帕病毒在1999年仅在马来西亚有过疫情记录后,2001年在梅尔布尔首次袭击了尼帕病毒,从而每年都造成公共卫生问题。最近,这种致命的人畜共患病毒在印度喀拉拉邦造成死亡,该地区远离其通常流行的地区。它始于摄入尼帕病毒感染的生枣椰树汁和与感染者直接接触。早期诊断和严格隔离是预防疫情爆发的主要手段。强有力的公共卫生措施能够降低该病的发病率和死亡率。结论:考虑到尼帕病毒感染的高致死率,它现在是世界卫生组织列出的十种重点疾病之一。然而,有效的健康教育和感染控制实践仍然被认为是预防未来尼帕疫情的主要手段。Akmmc j 2021;12(1): 52-57
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 Materials & methods: Intensive web searching was done for documents and journals on Nipah Virus infection and Nipah outbreak from 1999 to 2018. A total of 279 research documents were found and about 40 papers, especially the PubMed indexed sources and newsletters distributed by different public health agencies were selected for the meta-analysis. Information gathered from the selected journals and documents were described in text and figures.
 Results: The analysis revealed that fruit bats of the Pteropus genus are the natural hosts of the virus. After documentation of only outbreak in Malaysia in 1999, Nipah virus struck in Meherpur in 2001 for the first time and thereby, creating a public health issue every year. Very recently, this deadly zoonotic virus caused fatality in Kerala, India which is far away from its usual prevalent region. It starts with the ingestion of Nipah infected raw date palm sap and direct contact with the infected person. Early diagnosis and strict isolation is the mainstay to prevent an outbreak. Strong public health measures can able to reduce both the frequency and mortality of the disease.
 Conclusions: Nipah virus infection is now one of the ten priority diseases listed by the World Health Organization considering its high fatality rate. However, effective health education and infection control practice is still considered as the mainstay of prevention of future Nipah outbreak.
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引用次数: 0
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Anwer Khan Modern Medical College Journal
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