Pub Date : 2024-01-13DOI: 10.21608/mjvm.2023.241424.1019
Ibrahim Rabah, Mohammad A. Nossair, ElSayed Hafez, Mohamed Elkamshishi, Eman Khalifa
Helicobacter pylori is considered as one of the most threatening zoonosis all over the world with over half of the world ’ s population was suffered from this contagious pathogen. The aim of the study was to determine the H. pylori prevalence rate between human and dogs in Matrouh Province through examining 200 stool samples from both hosts using ELISA based detection of H. pylori antigen and 16S rRNA PCR. The results of the overall prevalence H. pylori in the current study by PCR and ELISA was 42% and 47.5%, respectively. Based on the ELISA results, it was revealed that the prevalence in dogs was 51% with statistically significant association between the prevalence and the age groups or dog breeds. On the other hand, no statistically significant associations were found between H. pylori prevalence and sex, locality, and health status of the examined dogs. Furthermore, the ELISA-based prevalence of the disease in human was 44% being higher in smokers and dyspeptic patients than non-smokers and apparently healthy individuals with statistically significant relationship between the prevalence and both smoking habits and health status. Conclusively, our findings suggested that companion animals could transmit the infection to humans.
{"title":"Prevalence of Helicobacter pylori and Associated Risk Factors among Dyspeptic Patients and Dogs in Matrouh Province Regarding the Zoonotic Risks","authors":"Ibrahim Rabah, Mohammad A. Nossair, ElSayed Hafez, Mohamed Elkamshishi, Eman Khalifa","doi":"10.21608/mjvm.2023.241424.1019","DOIUrl":"https://doi.org/10.21608/mjvm.2023.241424.1019","url":null,"abstract":"Helicobacter pylori is considered as one of the most threatening zoonosis all over the world with over half of the world ’ s population was suffered from this contagious pathogen. The aim of the study was to determine the H. pylori prevalence rate between human and dogs in Matrouh Province through examining 200 stool samples from both hosts using ELISA based detection of H. pylori antigen and 16S rRNA PCR. The results of the overall prevalence H. pylori in the current study by PCR and ELISA was 42% and 47.5%, respectively. Based on the ELISA results, it was revealed that the prevalence in dogs was 51% with statistically significant association between the prevalence and the age groups or dog breeds. On the other hand, no statistically significant associations were found between H. pylori prevalence and sex, locality, and health status of the examined dogs. Furthermore, the ELISA-based prevalence of the disease in human was 44% being higher in smokers and dyspeptic patients than non-smokers and apparently healthy individuals with statistically significant relationship between the prevalence and both smoking habits and health status. Conclusively, our findings suggested that companion animals could transmit the infection to humans.","PeriodicalId":486819,"journal":{"name":"Matrouh Journal of Veterinary Medicine","volume":"19 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140509241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-13DOI: 10.21608/mjvm.2024.336225
Shimaa Amer, R. Ghallab, Mohamed Eldakroury, Gamal El Amrawi
In the current study, we aimed to evaluate the efficacy of the treatment of the dairy cows suffering from endometritis using nano-oxytetracycline (OTC-NPs), platelet-rich plasma (PRP), and conventional oxytetracycline (OTC) based protocols. To accomplish this study a group of 30 cycling Holstein lactating dairy cows suffering from post-partum endometritis were divided into three equal groups. Group I was given 10 ml of nano-oxytetracycline intrauterine infusion, two doses with one week interval, group II was treated with three doses of 20 ml of oxytetracycline 5% intrauterine infusion at one week interval and group III was given two doses of 10 ml of their own platelets rich plasma (PRP) one week apart and third one in day four post estrus. Results showed that serum level of TNF-α and IL6 recorded a significant decrease in all treated groups and the higher average decrease was recorded in group-I followed by group-III and finally group-II. In addition, all the treatment protocols significantly and successfully decreased the uterine thickness as compared to uterine thickness before treatment. In conclusion, and based on the changes in serum pro-inflammatory cytokines level, treatment with nano-oxytetracycline was more efficient in treatment of endometritis, followed by PRP and finally the conventional oxytetracycline.
{"title":"Advanced Clinical Trials in Treatment of Postpartum Endometritis in Holstein Dairy Cows","authors":"Shimaa Amer, R. Ghallab, Mohamed Eldakroury, Gamal El Amrawi","doi":"10.21608/mjvm.2024.336225","DOIUrl":"https://doi.org/10.21608/mjvm.2024.336225","url":null,"abstract":"In the current study, we aimed to evaluate the efficacy of the treatment of the dairy cows suffering from endometritis using nano-oxytetracycline (OTC-NPs), platelet-rich plasma (PRP), and conventional oxytetracycline (OTC) based protocols. To accomplish this study a group of 30 cycling Holstein lactating dairy cows suffering from post-partum endometritis were divided into three equal groups. Group I was given 10 ml of nano-oxytetracycline intrauterine infusion, two doses with one week interval, group II was treated with three doses of 20 ml of oxytetracycline 5% intrauterine infusion at one week interval and group III was given two doses of 10 ml of their own platelets rich plasma (PRP) one week apart and third one in day four post estrus. Results showed that serum level of TNF-α and IL6 recorded a significant decrease in all treated groups and the higher average decrease was recorded in group-I followed by group-III and finally group-II. In addition, all the treatment protocols significantly and successfully decreased the uterine thickness as compared to uterine thickness before treatment. In conclusion, and based on the changes in serum pro-inflammatory cytokines level, treatment with nano-oxytetracycline was more efficient in treatment of endometritis, followed by PRP and finally the conventional oxytetracycline.","PeriodicalId":486819,"journal":{"name":"Matrouh Journal of Veterinary Medicine","volume":"16 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140509117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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