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Meta-Analysis: Triggering Factors of Atopic Dermatitis in Children 荟萃分析:儿童特应性皮炎的触发因素
Pub Date : 2023-02-25 DOI: 10.11594/jk-risk.02.2.3
Luthfiana Eka Sari, Arini Haq, Yustian Rakhmawati
Background: Atopic dermatitis is a non-communicable skin disorder characterized by intense itching. It is relapsing, recurring, and can have a negative impact on the quality of life of patients and their family members. Atopic dermatitis occurs most often in early infancy and childhood. Atopic dermatitis can occur if there is dysregulation of IgE resulting in a breakdown of the epidermal barrier. There are several factors that trigger the occurrence of atopic rheumatism in children, which can come from environmental factors or medical history. Aim: For this reason, this study aims to analyze the similarity of output regarding the magnitude of risk factors for atopic dermatitis in children. Methods: This study was analyzed using a meta-analysis using PRISMA, where there were 7 of 8654 articles that met the criteria for analysis. Meanwhile, the data presentation was carried out using a forest plot with a random effect statistical model. Results: The presence of pets, children living in environments that have pets (cats or dogs) are known to increase the risk of atopic dermatitis by 5 times compared to children living in environments that do not have animals. pet. The health history factor seen from exclusive breastfeeding, where babies who are exclusively breastfed are significantly less likely to experience atopic dermatitis by 12.5 times compared to babies who are not exclusively breastfed. Conclusion: Not giving exclusive breastfeeding and pets affect atopic dermatitis in children (p<0,05).
背景:特应性皮炎是一种以强烈瘙痒为特征的非传染性皮肤病。它是反复发作的,并可能对患者及其家庭成员的生活质量产生负面影响。特应性皮炎最常见于婴儿期和儿童期。如果IgE失调导致表皮屏障破裂,就会发生特应性皮炎。触发儿童特应性风湿病发生的因素有很多,可能来自环境因素,也可能来自病史。目的:为此,本研究旨在分析儿童特应性皮炎危险因素大小输出的相似性。 方法:本研究采用PRISMA进行meta分析,8654篇文章中有7篇符合分析标准。同时,采用随机效应统计模型的森林样地进行数据呈现。 结果:宠物的存在,生活在有宠物(猫或狗)环境中的儿童患特应性皮炎的风险是生活在没有动物环境中的儿童的5倍。宠物。从纯母乳喂养看到的健康史因素,纯母乳喂养的婴儿患特应性皮炎的可能性比非纯母乳喂养的婴儿低12.5倍。结论:不给予纯母乳喂养和宠物会影响儿童特应性皮炎(p< 0.05)。
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