Huei Ruey Ong, Wan Mohd Eqhwan Iskandar Wan Saiful Bahri, Amar Hisyam Harun, Md. Maksudur Rahman Khan, Chi Shein Hong, Muhammad Khairul Anuar Mohamed
In this work, carbon nanosphere derived from a waste rice husk (RH) were prepared through chemical treatment and calcination process. Moreover, the carbon nanofluids (CNF) were developed using simple chemical treatment assisted by ultrasound technique. Different composition of carbon nanosphere (CNS) were taken into experiment to determine the optimum and best properties. Ultrasound techniques were introduced in this study to reduce the agglomeration of the particle. Surface morphology of CNS were analysed by Scanning Electron Microscopy (SEM). The sphere shape from the particle/grain were identified from the nanoparticle and proves the terms of “nanosphere”. Viscosity of the nanofluids were studied by rheological testing (Antoon PAR, MAR 3). Flow curve of nanofluids showed that at minimum inclusion of CNS improved the stress of the fluid significantly. More to the addition, dynamic viscosity measure possesses that addition of CNS stabilized the properties of the fluid compared to virgin base fluid. The stability of the CNF was investigated through UV-Vis. Findings shows that, the stability of the nanofluids stabilized starting from 1 week onwards as evidenced by UV-Visible spectrophotometer analysis. Furthermore, little to no precipitate noticed even after 8 weeks. This work offers greener approach for nanofluids which organic derived and environmentally friendly (very low percentage of nanoparticle, 0.02 vol% (equivalent to 0.002 wt %).
{"title":"Study on Rheological and Stability of Natural Derived Carbon Nanosphere Nanofluids","authors":"Huei Ruey Ong, Wan Mohd Eqhwan Iskandar Wan Saiful Bahri, Amar Hisyam Harun, Md. Maksudur Rahman Khan, Chi Shein Hong, Muhammad Khairul Anuar Mohamed","doi":"10.11113/jomalisc.v2.21","DOIUrl":"https://doi.org/10.11113/jomalisc.v2.21","url":null,"abstract":"In this work, carbon nanosphere derived from a waste rice husk (RH) were prepared through chemical treatment and calcination process. Moreover, the carbon nanofluids (CNF) were developed using simple chemical treatment assisted by ultrasound technique. Different composition of carbon nanosphere (CNS) were taken into experiment to determine the optimum and best properties. Ultrasound techniques were introduced in this study to reduce the agglomeration of the particle. Surface morphology of CNS were analysed by Scanning Electron Microscopy (SEM). The sphere shape from the particle/grain were identified from the nanoparticle and proves the terms of “nanosphere”. Viscosity of the nanofluids were studied by rheological testing (Antoon PAR, MAR 3). Flow curve of nanofluids showed that at minimum inclusion of CNS improved the stress of the fluid significantly. More to the addition, dynamic viscosity measure possesses that addition of CNS stabilized the properties of the fluid compared to virgin base fluid. The stability of the CNF was investigated through UV-Vis. Findings shows that, the stability of the nanofluids stabilized starting from 1 week onwards as evidenced by UV-Visible spectrophotometer analysis. Furthermore, little to no precipitate noticed even after 8 weeks. This work offers greener approach for nanofluids which organic derived and environmentally friendly (very low percentage of nanoparticle, 0.02 vol% (equivalent to 0.002 wt %).","PeriodicalId":489381,"journal":{"name":"Journal of Materials in Life Sciences (JOMALISC)","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136350997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anis Athirah Kharuddin, Rosnani Hasham, Fathilah Ali, Nadia Adrus, Jamarosliza Jamaluddin, Roshanida Abdul Rahman, Mariani Abdul Hamid, Harisun Yaakob
Our gastrointestinal tract's (GI) functioning is influenced by a diverse collection of bacteria. Prebiotics are one of the most promising strategies for changing the composition of the gut microbiota and the metabolic process. Prebiotics can be thought of as a 'food' for probiotics in general. Prebiotics in the diet have been shown in numerous studies to be an effective way to manipulate the intestinal microbiota through diet. This topic has attracted widespread attention and is being managed for the benefit of human health. Because of the rising demand for prebiotics, a new source of prebiotics is needed such as plants, one that is reasonably inexpensive when compared to commercially available prebiotics. Turmeric and Garcinia atroviridis are common and cheap cooking ingredients used in Malaysia that are rich in dietary polyphenols and able to modulate gut and intestinal microbiota. Therefore, the purpose of this review is to emphasize the prebiotic potential of naturally occurring non-digestible carbohydrates in various plants.
{"title":"Potential Use of Phytochemical Extract as Prebiotic Compounds – A Brief Review","authors":"Anis Athirah Kharuddin, Rosnani Hasham, Fathilah Ali, Nadia Adrus, Jamarosliza Jamaluddin, Roshanida Abdul Rahman, Mariani Abdul Hamid, Harisun Yaakob","doi":"10.11113/jomalisc.v2.26","DOIUrl":"https://doi.org/10.11113/jomalisc.v2.26","url":null,"abstract":"Our gastrointestinal tract's (GI) functioning is influenced by a diverse collection of bacteria. Prebiotics are one of the most promising strategies for changing the composition of the gut microbiota and the metabolic process. Prebiotics can be thought of as a 'food' for probiotics in general. Prebiotics in the diet have been shown in numerous studies to be an effective way to manipulate the intestinal microbiota through diet. This topic has attracted widespread attention and is being managed for the benefit of human health. Because of the rising demand for prebiotics, a new source of prebiotics is needed such as plants, one that is reasonably inexpensive when compared to commercially available prebiotics. Turmeric and Garcinia atroviridis are common and cheap cooking ingredients used in Malaysia that are rich in dietary polyphenols and able to modulate gut and intestinal microbiota. Therefore, the purpose of this review is to emphasize the prebiotic potential of naturally occurring non-digestible carbohydrates in various plants.","PeriodicalId":489381,"journal":{"name":"Journal of Materials in Life Sciences (JOMALISC)","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136351001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to evaluate the drug-likeness, pharmacokinetic and safety prediction of six types of anthocyanins (ANC) as well as virtual molecular interaction between ANC and 5-hydroxytryptamine-2C (5HT-2C) receptor for antagonist target of antidepressant drug development. The Lipinski rule of five was used to predict the oral drug-likeness of ANC. The pharmacokinetic and safety prediction was analyzed with a free accessible web server. The ligands of ANC were retrieved from PubChem National Centre for Biotechnology Information (NCBI) database. The protein of the 5HT-2C receptor was obtained from Protein Data Bank. Molecular docking was performed by PyRx software and visualized using Discovery Studio Software. The results showed ANC is proposed as an oral drug candidate. The pharmacokinetic prediction of ANC was demonstrated to have high absorption in the intestinal route, solubility in the aqueous phase, capability to evade hepatic first-pass metabolism and high total clearance from the kidney. Virtual toxicity prediction showed a higher threshold of chronic lethal dose than control with no toxicity on the salmonella typhimurium reverses mutation assay (AMES) test, liver, and skin. Molecular prediction found ANC type of delphinidin has the most similar interaction site with the control antagonist ligand on the 5HT-2C receptor which is facilitated with hydrogen bonds and hydrophobic bonds at amino residues of Trp324, Phe328, Ala222 and Val135. We concluded ANC particularly delphinidin is proposed as an oral drug candidate potentially used as a 5HT-2C receptor antagonist and thus, further in vitro and in vivo studies are necessary to confirm the effect on antidepressant activity.
本研究旨在评价6种花青素(ANC)的药物相似性、药代动力学和安全性预测，以及ANC与5-羟色胺- 2c (5HT-2C)受体作为抗抑郁药物拮抗靶点的虚拟分子相互作用。采用利平斯基五法则预测ANC的口服药物相似性。通过免费访问的web服务器分析药代动力学和安全性预测。ANC的配体检索自PubChem国家生物技术信息中心(NCBI)数据库。5HT-2C受体蛋白来源于protein Data Bank。通过PyRx软件进行分子对接，并使用Discovery Studio软件进行可视化。结果表明，ANC可作为一种口服候选药物。ANC的药代动力学预测被证明具有肠路吸收高、水相溶解度高、能够逃避肝脏第一次代谢和肾脏总清除率高的特点。虚拟毒性预测显示鼠伤寒沙门菌反向突变试验(AMES)、肝脏和皮肤的慢性致死剂量阈值高于无毒性的对照组。分子预测发现ANC型飞鸽素与5HT-2C受体上对照拮抗剂配体的相互作用位点最为相似，在Trp324、Phe328、Ala222和Val135的氨基残基上存在氢键和疏水键促进作用。我们的结论是，ANC特别是飞燕草苷被建议作为一种口服候选药物，可能用作5HT-2C受体拮抗剂，因此，需要进一步的体外和体内研究来证实其抗抑郁活性的作用。
{"title":"In Silico Study of the 5-Hydroxytryptamine-2C Receptor Antagonist Activity of Anthocyanins as Antidepressant Therapy","authors":"Nia Kurnianingsih, Novita Titis Harbiyanti, Ardani Galih Prakosa, Retty Ratnawati","doi":"10.11113/jomalisc.v2.29","DOIUrl":"https://doi.org/10.11113/jomalisc.v2.29","url":null,"abstract":"This study aimed to evaluate the drug-likeness, pharmacokinetic and safety prediction of six types of anthocyanins (ANC) as well as virtual molecular interaction between ANC and 5-hydroxytryptamine-2C (5HT-2C) receptor for antagonist target of antidepressant drug development. The Lipinski rule of five was used to predict the oral drug-likeness of ANC. The pharmacokinetic and safety prediction was analyzed with a free accessible web server. The ligands of ANC were retrieved from PubChem National Centre for Biotechnology Information (NCBI) database. The protein of the 5HT-2C receptor was obtained from Protein Data Bank. Molecular docking was performed by PyRx software and visualized using Discovery Studio Software. The results showed ANC is proposed as an oral drug candidate. The pharmacokinetic prediction of ANC was demonstrated to have high absorption in the intestinal route, solubility in the aqueous phase, capability to evade hepatic first-pass metabolism and high total clearance from the kidney. Virtual toxicity prediction showed a higher threshold of chronic lethal dose than control with no toxicity on the salmonella typhimurium reverses mutation assay (AMES) test, liver, and skin. Molecular prediction found ANC type of delphinidin has the most similar interaction site with the control antagonist ligand on the 5HT-2C receptor which is facilitated with hydrogen bonds and hydrophobic bonds at amino residues of Trp324, Phe328, Ala222 and Val135. We concluded ANC particularly delphinidin is proposed as an oral drug candidate potentially used as a 5HT-2C receptor antagonist and thus, further in vitro and in vivo studies are necessary to confirm the effect on antidepressant activity.","PeriodicalId":489381,"journal":{"name":"Journal of Materials in Life Sciences (JOMALISC)","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136351003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohd Hayrie Mohd Hatta, Kalaivani Batumalaie, Juan Matmin, Johnathan Malagobadan
The rapid outbreak of the deadly and contagious SARS-CoV-2 virus in 2019 that caused COVID-19 disease has demanded the development of novel antiviral materials. Since medical treatment and drug evaluation and approval by health authorities takes a longer time, nanomaterials can play a significant role in combating deadly disease. Carbon-based materials, such as carbon nanotubes (CNTs), graphene, fullerene, and carbon quantum dots (CQDs), have been widely reported in the literature as contributing to fighting the viral disease. Among them, CQDs have received significant attention as bionanomaterials recently, particularly in the biomedical field to treat various viral infections. Therefore, this mini-review discusses the recent achievements of CQDs and graphene quantum dots (GQDs) as bionanomaterials in fighting viral disease, specifically COVID-19 and other COVID-19-related works such as sensing and treatment, as well as virus inhibition.
{"title":"Carbon and Graphene Quantum Dots as Bionanomaterials: A Perspective View of COVID–19","authors":"Mohd Hayrie Mohd Hatta, Kalaivani Batumalaie, Juan Matmin, Johnathan Malagobadan","doi":"10.11113/jomalisc.v2.30","DOIUrl":"https://doi.org/10.11113/jomalisc.v2.30","url":null,"abstract":"The rapid outbreak of the deadly and contagious SARS-CoV-2 virus in 2019 that caused COVID-19 disease has demanded the development of novel antiviral materials. Since medical treatment and drug evaluation and approval by health authorities takes a longer time, nanomaterials can play a significant role in combating deadly disease. Carbon-based materials, such as carbon nanotubes (CNTs), graphene, fullerene, and carbon quantum dots (CQDs), have been widely reported in the literature as contributing to fighting the viral disease. Among them, CQDs have received significant attention as bionanomaterials recently, particularly in the biomedical field to treat various viral infections. Therefore, this mini-review discusses the recent achievements of CQDs and graphene quantum dots (GQDs) as bionanomaterials in fighting viral disease, specifically COVID-19 and other COVID-19-related works such as sensing and treatment, as well as virus inhibition.","PeriodicalId":489381,"journal":{"name":"Journal of Materials in Life Sciences (JOMALISC)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136350998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Immobilized enzymes are more robust and resistant to environmental changes than free enzymes in solution. More crucially, the immobilized enzyme systems' heterogeneity enables facile recovery of enzymes and products, multiple reuses, continuous enzymatic processes, quick reaction termination, and a more comprehensive range of bioreactor designs. This paper examines recent findings on enzyme immobilization using diverse approaches for various uses. The information gathered from the reactions catalyzed by the encapsulated tyrosinase provided a good view of hetero-biocatalysts in the phenol biosensor industries. This review proposes an effective method for immobilizing tyrosinase biomolecules into a silica aerogel matrix. Silica matrix has been utilized to encapsulate a wide range of biomolecules, mainly in sol-gel composites. We also discovered that silica aerogel synthesized from sol-gel method retains all the immobilized enzyme activity. The use of a silica matrix for enzyme immobilization, in conjunction with a moderate immobilization method, results in the successful retention of enzyme activity. Future studies should explore practical encapsulating approaches and inventively modified supports to enhance the commercialization of immobilized enzymes and offer fresh perspectives to the industrial sector.
{"title":"Immobilization of Tyrosinase and Its Application","authors":"Nor Suriani Sani, Nik Ahmad Nizam Nik Malek","doi":"10.11113/jomalisc.v2.16","DOIUrl":"https://doi.org/10.11113/jomalisc.v2.16","url":null,"abstract":"Immobilized enzymes are more robust and resistant to environmental changes than free enzymes in solution. More crucially, the immobilized enzyme systems' heterogeneity enables facile recovery of enzymes and products, multiple reuses, continuous enzymatic processes, quick reaction termination, and a more comprehensive range of bioreactor designs. This paper examines recent findings on enzyme immobilization using diverse approaches for various uses. The information gathered from the reactions catalyzed by the encapsulated tyrosinase provided a good view of hetero-biocatalysts in the phenol biosensor industries. This review proposes an effective method for immobilizing tyrosinase biomolecules into a silica aerogel matrix. Silica matrix has been utilized to encapsulate a wide range of biomolecules, mainly in sol-gel composites. We also discovered that silica aerogel synthesized from sol-gel method retains all the immobilized enzyme activity. The use of a silica matrix for enzyme immobilization, in conjunction with a moderate immobilization method, results in the successful retention of enzyme activity. Future studies should explore practical encapsulating approaches and inventively modified supports to enhance the commercialization of immobilized enzymes and offer fresh perspectives to the industrial sector.","PeriodicalId":489381,"journal":{"name":"Journal of Materials in Life Sciences (JOMALISC)","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136350999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siti Pauliena Mohd Bohari, Nursyafika Az Zahra Ajan
In recent years, the development of wound dressings has changed from a passive to an active form by adding antiseptic agents such as polyvinylpyrrolidone (PVPI) and nanoparticles such as silver nanoparticles to facilitate the wound healing process. However, PVPI is toxic to human skin fibroblasts, and silver nanoparticles may result in metal accumulation in the tissues due to their nanosize. Therefore, a new approach to using natural sources from plants such as Hibiscus sabdariffa Linn. (HSL) is promising due to its phytochemical constituents that can serve as a potential therapeutic agent in wound dressings. In this study, freeze-dried alginate/gauze (FDA/gauze) without and with HS extract and calcium alginate/gauze (CA /gauze) with and without HS extract were developed by freeze-drying and gelation, respectively. This study aimed to characterize the properties of alginate/gauze-dressings as wound dressings. The morphology of the designed dressing; FDA/gauze, looks evenly distributed on the surface of the gauze compared to CA/gauze. It was found that FDA/gauze dressings have higher water absorbency than CA /gauze dressings, ranging from 690.43 to 1340.86% from day 1 until day 14. The percentage of water uptake ability increases as the concentration of alginate increases. In addition, the seeded human skin fibroblasts' growth on the alginate/gauze dressings infused with HSL extract growth in clustered, bright, and colourless proves that the cells were viable. Thus, the addition of HSL extract shows to support the process of cell viability.
{"title":"Alginate/Gauze Incorporated with Hibiscus sabdariffa Linn. Extract as a Bioactive Agent for Wound Dressing Application","authors":"Siti Pauliena Mohd Bohari, Nursyafika Az Zahra Ajan","doi":"10.11113/jomalisc.v2.32","DOIUrl":"https://doi.org/10.11113/jomalisc.v2.32","url":null,"abstract":"In recent years, the development of wound dressings has changed from a passive to an active form by adding antiseptic agents such as polyvinylpyrrolidone (PVPI) and nanoparticles such as silver nanoparticles to facilitate the wound healing process. However, PVPI is toxic to human skin fibroblasts, and silver nanoparticles may result in metal accumulation in the tissues due to their nanosize. Therefore, a new approach to using natural sources from plants such as Hibiscus sabdariffa Linn. (HSL) is promising due to its phytochemical constituents that can serve as a potential therapeutic agent in wound dressings. In this study, freeze-dried alginate/gauze (FDA/gauze) without and with HS extract and calcium alginate/gauze (CA /gauze) with and without HS extract were developed by freeze-drying and gelation, respectively. This study aimed to characterize the properties of alginate/gauze-dressings as wound dressings. The morphology of the designed dressing; FDA/gauze, looks evenly distributed on the surface of the gauze compared to CA/gauze. It was found that FDA/gauze dressings have higher water absorbency than CA /gauze dressings, ranging from 690.43 to 1340.86% from day 1 until day 14. The percentage of water uptake ability increases as the concentration of alginate increases. In addition, the seeded human skin fibroblasts' growth on the alginate/gauze dressings infused with HSL extract growth in clustered, bright, and colourless proves that the cells were viable. Thus, the addition of HSL extract shows to support the process of cell viability.","PeriodicalId":489381,"journal":{"name":"Journal of Materials in Life Sciences (JOMALISC)","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136351002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wan Rosmiza Zana Wan Dagang, Nuraihanah Najihah Zaidi
A variety of flocculants have been used to treat wastewater by agglomerating various colloidal substances and cells. Due to the adverse effects and high cost of conventional flocculants, bioflocculant which are originally produced by microorganisms are gaining attention. Therefore, this study aimed to identify the biofilm-bioflocculant-producing bacteria which was isolated from palm oil mill effluent in Johor, Malaysia. The isolated bacteria were identified by their colony morphology, Gram-staining and 16S rRNA gene sequence analysis. All isolates were subjected to bioflocculant assay with kaolin clay suspension as a model of wastewater to assess the flocculation efficiency of the bacterial bioflocculants. Two different isolates were successfully identified as Gram-negative bacteria Stenotrophomonas koreensis TR6-01 and Alishewanella agri BL06. S. koreensis TR6-01 shows the highest flocculating activity at 82.79%, followed by A. agri BL06 with 78.52%, respectively. The strongest biofilm producer was shown by S. koreensis TR6-01 and thus, indicates good candidate for future wastewater treatment technology.
{"title":"Isolation of Biofilm-Bioflocculant Producing Bacteria from Palm Oil Mill Effluent","authors":"Wan Rosmiza Zana Wan Dagang, Nuraihanah Najihah Zaidi","doi":"10.11113/jomalisc.v2.28","DOIUrl":"https://doi.org/10.11113/jomalisc.v2.28","url":null,"abstract":"A variety of flocculants have been used to treat wastewater by agglomerating various colloidal substances and cells. Due to the adverse effects and high cost of conventional flocculants, bioflocculant which are originally produced by microorganisms are gaining attention. Therefore, this study aimed to identify the biofilm-bioflocculant-producing bacteria which was isolated from palm oil mill effluent in Johor, Malaysia. The isolated bacteria were identified by their colony morphology, Gram-staining and 16S rRNA gene sequence analysis. All isolates were subjected to bioflocculant assay with kaolin clay suspension as a model of wastewater to assess the flocculation efficiency of the bacterial bioflocculants. Two different isolates were successfully identified as Gram-negative bacteria Stenotrophomonas koreensis TR6-01 and Alishewanella agri BL06. S. koreensis TR6-01 shows the highest flocculating activity at 82.79%, followed by A. agri BL06 with 78.52%, respectively. The strongest biofilm producer was shown by S. koreensis TR6-01 and thus, indicates good candidate for future wastewater treatment technology.","PeriodicalId":489381,"journal":{"name":"Journal of Materials in Life Sciences (JOMALISC)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136351000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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