首页 > 最新文献

Medic.ro最新文献

英文 中文
Management of prophylaxis in Streptococcus pneumoniae infection 肺炎链球菌感染的预防管理
Pub Date : 2023-01-01 DOI: 10.26416/med.154.4.2023.8710
Ioana-Maria Bloj, Emese Orban, Edith-Simona Ianoşi, Remus Şipoş
Introduction. In view of the continuing development of vaccines for various diseases, there is a need not only to keep health professionals informed, but also to understand how they perceive the risks of certain diseases for certain groups of patients. It is particularly important to identify how the perception of immunizations by both the medical profession and the direct beneficiaries, the patients, can be influenced. Materials and method. The study was based on a survey of 42 family physicians attending a symposium on the ma­nage­ment of patients with Streptococcus pneumoniae in­fec­tion. Data had been collected from participants be­fore they heard the lectures at the event. Results. The in­for­ma­tion gathered from the survey revealed that doc­tors consider it useful for the health system to support im­mu­ni­za­tion programs in order to increase immunization rates. It also revealed that the way one vaccination campaign is car­ried out can influence another, and that the doctor has a significant role in influencing the patient’s immunization. Conclusions. The success of vaccination campaigns in ensuring a good immunization rate depends on a good correlation between the involvement of the health system through the national immunization program, the health insurance system and the work of doctors who can significantly influence the patient’s decision to be vaccinated.
介绍。鉴于针对各种疾病的疫苗不断开发,不仅需要让卫生专业人员了解情况,而且需要了解他们如何看待某些疾病对某些患者群体的风险。特别重要的是确定如何影响医疗专业人员和直接受益者即患者对免疫接种的看法。材料和方法。这项研究是基于对参加肺炎链球菌感染患者管理研讨会的42名家庭医生的调查。在参加活动的人听讲座之前,已经收集了他们的数据。结果。从调查中收集到的信息显示,医生认为卫生系统支持免疫接种计划以提高免疫率是有用的。调查还显示,一项疫苗接种运动的开展方式可能影响另一项运动,医生在影响患者的免疫接种方面发挥着重要作用。结论。疫苗接种运动在确保良好免疫接种率方面的成功取决于卫生系统通过国家免疫规划的参与、健康保险系统和医生的工作之间的良好相关性,医生可以对患者接种疫苗的决定产生重大影响。
{"title":"Management of prophylaxis in Streptococcus pneumoniae infection","authors":"Ioana-Maria Bloj, Emese Orban, Edith-Simona Ianoşi, Remus Şipoş","doi":"10.26416/med.154.4.2023.8710","DOIUrl":"https://doi.org/10.26416/med.154.4.2023.8710","url":null,"abstract":"Introduction. In view of the continuing development of vaccines for various diseases, there is a need not only to keep health professionals informed, but also to understand how they perceive the risks of certain diseases for certain groups of patients. It is particularly important to identify how the perception of immunizations by both the medical profession and the direct beneficiaries, the patients, can be influenced. Materials and method. The study was based on a survey of 42 family physicians attending a symposium on the ma­nage­ment of patients with Streptococcus pneumoniae in­fec­tion. Data had been collected from participants be­fore they heard the lectures at the event. Results. The in­for­ma­tion gathered from the survey revealed that doc­tors consider it useful for the health system to support im­mu­ni­za­tion programs in order to increase immunization rates. It also revealed that the way one vaccination campaign is car­ried out can influence another, and that the doctor has a significant role in influencing the patient’s immunization. Conclusions. The success of vaccination campaigns in ensuring a good immunization rate depends on a good correlation between the involvement of the health system through the national immunization program, the health insurance system and the work of doctors who can significantly influence the patient’s decision to be vaccinated.","PeriodicalId":489459,"journal":{"name":"Medic.ro","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134888979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Family doctor, an important element in the pilot project for the screening of chronic viral hepatitis B/C/D (LIVERO 2) 家庭医生:筛查慢性乙型/丙型/丁型肝炎试点项目的重要组成部分(LIVERO 2)
Pub Date : 2023-01-01 DOI: 10.26416/med.154.4.2023.8714
Mihaela Udrescu
Romania is one of the European countries with a high pre­va­lence of hepatitis viruses B, C and D infections. The World Health Organization objective is to eradicate the chronic in­fec­tions with hepatitis viruses B, C and D until 2030. The era­di­ca­tion of these infections is possible only if all people in­fec­ted with B, C or D hepatitis viruses are identified, all of them are correctly treated and monitored, and their contacts are tested, treated or vaccinated. This is a very strong issue, theo­re­tic­ally possible, but in the current practice, it is need for realistic objectives. LIVERO 2 is an important pilot project for the screening of viral hepatitis B, C and D, addressed to vulnerable people (more than 50% of tested people are man­da­tory from vulnerable categories). Family doctors had an important contribution in this project, the majority of the sub­jects being tested in their medical offices.
罗马尼亚是乙型、丙型和丁型肝炎病毒感染率较高的欧洲国家之一。世界卫生组织的目标是到2030年根除乙型、丙型和丁型肝炎病毒的慢性感染。只有在所有乙型、丙型或丁型肝炎病毒感染者都得到确认,所有人都得到正确治疗和监测,并对其接触者进行检测、治疗或接种疫苗的情况下,才有可能对这些感染进行诊断。这是一个非常强烈的问题,理论上是可能的,但在目前的实践中,需要现实的目标。LIVERO 2是筛查病毒性乙型、丙型和丁型肝炎的一个重要试点项目,面向弱势群体(50%以上的受检测人群是来自弱势群体的男性)。家庭医生在这个项目中作出了重要贡献,大多数受试者在他们的医疗办公室接受测试。
{"title":"Family doctor, an important element in the pilot project for the screening of chronic viral hepatitis B/C/D (LIVERO 2)","authors":"Mihaela Udrescu","doi":"10.26416/med.154.4.2023.8714","DOIUrl":"https://doi.org/10.26416/med.154.4.2023.8714","url":null,"abstract":"Romania is one of the European countries with a high pre­va­lence of hepatitis viruses B, C and D infections. The World Health Organization objective is to eradicate the chronic in­fec­tions with hepatitis viruses B, C and D until 2030. The era­di­ca­tion of these infections is possible only if all people in­fec­ted with B, C or D hepatitis viruses are identified, all of them are correctly treated and monitored, and their contacts are tested, treated or vaccinated. This is a very strong issue, theo­re­tic­ally possible, but in the current practice, it is need for realistic objectives. LIVERO 2 is an important pilot project for the screening of viral hepatitis B, C and D, addressed to vulnerable people (more than 50% of tested people are man­da­tory from vulnerable categories). Family doctors had an important contribution in this project, the majority of the sub­jects being tested in their medical offices.","PeriodicalId":489459,"journal":{"name":"Medic.ro","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134889454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aspects of acute otitis media etiology and pathogenesis 急性中耳炎的病因及发病机制
Pub Date : 2023-01-01 DOI: 10.26416/med.154.4.2023.8711
Vasilica Ungureanu
Otitis media (OM) remains a major cause of morbidity worl­d­wide, representing one of the complications of up­per res­­pi­­ra­­to­­ry tract (URT) infections, especially in small chil­dren. The etiology of acute otitis media (AOM) can be viral, bac­te­rial, viral-bacterial or bacterial-bacterial co­in­fec­tions. The most common bacterial agents causing oti­tis media are Streptococcus pneumoniae, Hae­mo­phi­lus in­flu­en­zae and Moraxella catarrhalis. Vi­ru­ses that can cause URT infections (respiratory syncytial vi­rus, co­ro­na­vi­ru­ses, in­flu­en­za viruses, adenoviruses etc.) are in­crea­sing­ly re­cog­nized as contributors to the poly­mi­cro­bial pathogenesis of otitis media. Other bacterial agents (Strep­to­co­ccus pyogenes, Sta­phy­lo­coc­cus aureus, Pseu­do­mo­nas aeruginosa) have been rarely detected. Re­gar­ding the patho­ge­ne­sis of AOM, multiple me­cha­nisms con­tri­bu­ting to the synergistic relationship bet­ween URT viruses and primary bac­te­rial pathogens of oti­tis media have been iden­ti­fied and, although each of them has a specific effect, they all fall into the general ca­te­go­ry of com­pro­mi­sing the host’s im­mune func­tion and res­pi­ra­to­ry tract defense. An ini­tial vi­ral in­fec­tion of the URT is ne­ces­sary, which in­du­ces in­flam­ma­tion at this level and in the Eu­s­ta­­chian tube, pro­mo­ting bac­te­rial superinfection of the mid­­dle ear. Pre­ven­ting viral and bac­te­rial infections of the up­per res­pi­ra­to­ry tract in­fec­tions as­so­cia­ted with acute otitis me­­dia could reduce the in­ci­dence of middle ear infections in child­­hood.
中耳炎(OM)仍然是世界范围内发病率的主要原因之一,是上呼吸道感染的并发症之一,特别是在幼儿中。急性中耳炎(AOM)的病因可以是病毒、细菌-病毒、病毒-细菌或细菌-细菌共感染。引起中耳炎的最常见细菌是肺炎链球菌、流感弧菌和卡他莫拉菌。可引起上呼吸道感染的病毒(呼吸道合胞病毒、co - na - vi-rus病毒、流感病毒、腺病毒等)越来越多地被认为是中耳炎多微生物发病机制的贡献者。其他细菌制剂(链球菌-化脓球菌,金黄色葡萄球菌,铜绿假球菌)很少被检测到。在AOM的致病机制方面,目前已确定了多种机制来促进URT病毒与中耳炎媒介的原发细菌病原体之间的协同关系,虽然每种机制都有特定的作用,但都属于共同促进宿主免疫功能和免疫通道防御的一般模式。上呼吸道最初的病毒感染是新生的,它会引起上呼吸道和输卵管的炎症,促进中耳和中耳的细菌重复感染。预防与急性中耳炎相关的上呼吸道感染的病毒和细菌感染可以降低儿童中耳感染的发生率。
{"title":"Aspects of acute otitis media etiology and pathogenesis","authors":"Vasilica Ungureanu","doi":"10.26416/med.154.4.2023.8711","DOIUrl":"https://doi.org/10.26416/med.154.4.2023.8711","url":null,"abstract":"Otitis media (OM) remains a major cause of morbidity worl­d­wide, representing one of the complications of up­per res­­pi­­ra­­to­­ry tract (URT) infections, especially in small chil­dren. The etiology of acute otitis media (AOM) can be viral, bac­te­rial, viral-bacterial or bacterial-bacterial co­in­fec­tions. The most common bacterial agents causing oti­tis media are Streptococcus pneumoniae, Hae­mo­phi­lus in­flu­en­zae and Moraxella catarrhalis. Vi­ru­ses that can cause URT infections (respiratory syncytial vi­rus, co­ro­na­vi­ru­ses, in­flu­en­za viruses, adenoviruses etc.) are in­crea­sing­ly re­cog­nized as contributors to the poly­mi­cro­bial pathogenesis of otitis media. Other bacterial agents (Strep­to­co­ccus pyogenes, Sta­phy­lo­coc­cus aureus, Pseu­do­mo­nas aeruginosa) have been rarely detected. Re­gar­ding the patho­ge­ne­sis of AOM, multiple me­cha­nisms con­tri­bu­ting to the synergistic relationship bet­ween URT viruses and primary bac­te­rial pathogens of oti­tis media have been iden­ti­fied and, although each of them has a specific effect, they all fall into the general ca­te­go­ry of com­pro­mi­sing the host’s im­mune func­tion and res­pi­ra­to­ry tract defense. An ini­tial vi­ral in­fec­tion of the URT is ne­ces­sary, which in­du­ces in­flam­ma­tion at this level and in the Eu­s­ta­­chian tube, pro­mo­ting bac­te­rial superinfection of the mid­­dle ear. Pre­ven­ting viral and bac­te­rial infections of the up­per res­pi­ra­to­ry tract in­fec­tions as­so­cia­ted with acute otitis me­­dia could reduce the in­ci­dence of middle ear infections in child­­hood.","PeriodicalId":489459,"journal":{"name":"Medic.ro","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134888965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ROCCAS II South-Muntenia – model of good practice in general practitioner office 南黑山-全科医生办公室良好实践的典范
Pub Date : 2023-01-01 DOI: 10.26416/med.154.4.2023.8715
Mihaela Paraschiv, Mihnea-Lucian Paraschiv
Background. Colorectal cancer is one of the malignancies that are diagnosed late and occupies the first places among the causes of death in Romania and worldwide. In the current study, we pointed out the major role of family me­di­cine in the prevention and early detection of colorectal can­cer through screening programs, such as ROCCAS II South-Muntenia pro­ject. Materials and method. For this retrospective study, a group of 411 people participated in a colorectal screening pro­gram, ROCCAS II Sud-Muntenia, between November 2021 and June 2023. Only people bet­ween 50 and 74 years old, who lived in South-Muntenia area, were included. The ex­clu­sion criteria were patients youn­ger than 49 years old and over 75, and the residence in any other region of the country. Re­sults. In this study, there were included 411 people, and 39 of them (9.48%) were identified with a high risk or with a very high risk of colo­rec­tal cancer. Out of the 24 people who ac­cep­ted to proceed with colonoscopy, one person (4.24%) had co­lo­rec­tal can­cer, 15 people (62.5%) had a pre­can­ce­rous lesion, and eight subjects (33.3%) had no lesion. Con­clu­sions. Overall, in this study, the colorectal screening program ROCCAS II South-Muntenia proved its benefits for those in­di­vi­duals at risk, and managed to prevent lesions that could evolve into cancer in the following years for 5.48% of the sub­jects at risk.
背景。结直肠癌是诊断较晚的恶性肿瘤之一,在罗马尼亚和全世界的死亡原因中居首位。在本研究中,我们通过筛查项目,如ROCCAS II South-Muntenia项目,指出家庭疫苗在预防和早期发现结直肠癌方面的主要作用。材料和方法。在这项回顾性研究中,一组411人参加了2021年11月至2023年6月期间的结肠直肠癌筛查项目ROCCAS II Sud-Muntenia。只有居住在muntenia南部地区的50至74岁的人被包括在内。排除标准为年龄小于49岁,年龄大于75岁,居住在国内任何其他地区的患者。Re-sults。本研究纳入了411人,其中39人(9.48%)被确定为结直肠癌的高风险或极高风险。在接受结肠镜检查的24人中,1人(4.24%)患有合并直肠癌,15人(62.5%)有癌前病变,8人(33.3%)没有病变。Con-clu-sions。总体而言,在本研究中,南muntenia结肠直肠癌筛查项目ROCCAS II证明了其对高危人群的益处,并成功预防了5.48%的高危人群在接下来的几年中可能演变为癌症的病变。
{"title":"ROCCAS II South-Muntenia – model of good practice in general practitioner office","authors":"Mihaela Paraschiv, Mihnea-Lucian Paraschiv","doi":"10.26416/med.154.4.2023.8715","DOIUrl":"https://doi.org/10.26416/med.154.4.2023.8715","url":null,"abstract":"Background. Colorectal cancer is one of the malignancies that are diagnosed late and occupies the first places among the causes of death in Romania and worldwide. In the current study, we pointed out the major role of family me­di­cine in the prevention and early detection of colorectal can­cer through screening programs, such as ROCCAS II South-Muntenia pro­ject. Materials and method. For this retrospective study, a group of 411 people participated in a colorectal screening pro­gram, ROCCAS II Sud-Muntenia, between November 2021 and June 2023. Only people bet­ween 50 and 74 years old, who lived in South-Muntenia area, were included. The ex­clu­sion criteria were patients youn­ger than 49 years old and over 75, and the residence in any other region of the country. Re­sults. In this study, there were included 411 people, and 39 of them (9.48%) were identified with a high risk or with a very high risk of colo­rec­tal cancer. Out of the 24 people who ac­cep­ted to proceed with colonoscopy, one person (4.24%) had co­lo­rec­tal can­cer, 15 people (62.5%) had a pre­can­ce­rous lesion, and eight subjects (33.3%) had no lesion. Con­clu­sions. Overall, in this study, the colorectal screening program ROCCAS II South-Muntenia proved its benefits for those in­di­vi­duals at risk, and managed to prevent lesions that could evolve into cancer in the following years for 5.48% of the sub­jects at risk.","PeriodicalId":489459,"journal":{"name":"Medic.ro","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134888971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coffee – between story and clinical studies. About coffee, cancer and gastrointestinal diseases 咖啡——介于故事和临床研究之间。关于咖啡,癌症和胃肠道疾病
Pub Date : 2023-01-01 DOI: 10.26416/med.154.4.2023.8713
Daniela-Ligia Moşneagă
Coffee has a long way from cultivation to use, and a history of thousands of years. Its qualities were initially attributed to caffeine, but research has identified multiple bioactive compounds with health effects. Clinical studies seek answers to questions related to the effects on longevity, me­­ta­­bo­lism, cardiovascular, gastrointestinal, neuropsy­cho­­­lo­­­gi­cal and cancer diseases. Future research is needed to recommend consumption and optimal quantity for pre­­ven­­tive or curative purposes. This article reviews issues re­la­ted to the history of coffee, its processing, chemical com­po­si­tion, relationship with gastrointestinal diseases and an­ti­car­cinogenic effects.
咖啡从种植到使用经历了漫长的历程,有几千年的历史。它的品质最初被归因于咖啡因,但研究已经发现了多种具有健康作用的生物活性化合物。临床研究寻求与长寿、心血管疾病、胃肠道、神经心理疾病和癌症疾病有关的问题的答案。需要进一步的研究来推荐用于预防或治疗目的的消费和最佳量。本文综述了与咖啡的历史、加工、化学成分、与胃肠道疾病的关系以及抗癌作用有关的问题。
{"title":"Coffee – between story and clinical studies. About coffee, cancer and gastrointestinal diseases","authors":"Daniela-Ligia Moşneagă","doi":"10.26416/med.154.4.2023.8713","DOIUrl":"https://doi.org/10.26416/med.154.4.2023.8713","url":null,"abstract":"Coffee has a long way from cultivation to use, and a history of thousands of years. Its qualities were initially attributed to caffeine, but research has identified multiple bioactive compounds with health effects. Clinical studies seek answers to questions related to the effects on longevity, me­­ta­­bo­lism, cardiovascular, gastrointestinal, neuropsy­cho­­­lo­­­gi­cal and cancer diseases. Future research is needed to recommend consumption and optimal quantity for pre­­ven­­tive or curative purposes. This article reviews issues re­la­ted to the history of coffee, its processing, chemical com­po­si­tion, relationship with gastrointestinal diseases and an­ti­car­cinogenic effects.","PeriodicalId":489459,"journal":{"name":"Medic.ro","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134888973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interdisciplinary monitoring of the patient with bronchial asthma 支气管哮喘患者的跨学科监测
Pub Date : 2023-01-01 DOI: 10.26416/med.154.4.2023.8709
Corina Eugenia Budin, Gabriela-Paula Pop
Bronchial asthma is characterized by chronic inflammation of the airways, associated with variable obstruction that li­mits air flow, and bronchial hyperactivity caused by va­rious sti­muli. The most common symptoms present in asth­ma­tic peo­ple are wheezing, dyspnea, cough and chest con­stric­tion. Bronch­ial asthma has a high variability, which makes its phenotyping very important for guiding treat­ment. Among the most common phenotypes, we mention allergic asth­ma, nonallergic asthma, late-onset bronchial asthma, per­sis­tent asthma with a fixed limitation of airflow, and asth­ma associated with obesity. A thorough anamnesis and performing spirometry with bronchodilator test help us to establish the diagnosis of bronchial asthma. The increase in the maximum expiratory volume per second (VEMS) by 12% and 200 ml from the initial value after taking four short-acting bronchodilator puffs is suggestive of bronchial asth­ma. The ACT questionnaire is used to show whether the di­sease is well controlled therapeutically. Exposure to allergens, over­weight, gastroesophageal reflux disease, rhinosinusitis, na­sal polyposis and smoking are some of the comorbidities and trig­­gers of bronchial asthma crisis. In terms of treatment, asth­matic patients have inhaled de­vices that contain as the first line of treatment inhaled cor­ti­co­ste­roids to which a long-acting beta2-agonist is added. Choosing the right the­ra­py for each patient is made on the basis of five stages of treatment, depending on the symp­to­ma­to­logy of each in­di­vi­dual patient, the phenotype of asth­ma and the co­mor­bi­di­ties present. Patients with severe asth­ma benefit from tar­ge­ted biological therapy.
支气管哮喘的特征是气道的慢性炎症,伴有限制空气流动的变异性阻塞,以及由各种刺激引起的支气管过度活跃。哮喘患者最常见的症状是喘息、呼吸困难、咳嗽和胸闷。支气管哮喘具有很高的变异性,这使得其表型对指导治疗非常重要。在最常见的表型中,我们提到过敏性哮喘、非过敏性哮喘、迟发性支气管哮喘、固定气流受限的持续性哮喘以及与肥胖相关的哮喘。彻底的记忆和支气管扩张试验的肺活量测定有助于我们确定支气管哮喘的诊断。服用四次短效支气管扩张剂后,最大每秒呼气量(VEMS)比初始值增加12%和200ml,提示支气管哮喘。ACT问卷用于显示疾病在治疗上是否得到良好控制。暴露于过敏原、超重、胃食管反流病、鼻窦炎、鼻腔息肉病和吸烟是支气管哮喘危象的一些合并症和诱发因素。在治疗方面,哮喘患者的吸入装置含有作为一线治疗的吸入co - ti - co - ste - roids,其中添加了长效β - 2激动剂。为每位患者选择合适的治疗方案是基于五个治疗阶段,这取决于每位患者的症状-病症-病症、哮喘的表型和存在的共病-病症。严重哮喘患者受益于靶向生物治疗。
{"title":"Interdisciplinary monitoring of the patient with bronchial asthma","authors":"Corina Eugenia Budin, Gabriela-Paula Pop","doi":"10.26416/med.154.4.2023.8709","DOIUrl":"https://doi.org/10.26416/med.154.4.2023.8709","url":null,"abstract":"Bronchial asthma is characterized by chronic inflammation of the airways, associated with variable obstruction that li­mits air flow, and bronchial hyperactivity caused by va­rious sti­muli. The most common symptoms present in asth­ma­tic peo­ple are wheezing, dyspnea, cough and chest con­stric­tion. Bronch­ial asthma has a high variability, which makes its phenotyping very important for guiding treat­ment. Among the most common phenotypes, we mention allergic asth­ma, nonallergic asthma, late-onset bronchial asthma, per­sis­tent asthma with a fixed limitation of airflow, and asth­ma associated with obesity. A thorough anamnesis and performing spirometry with bronchodilator test help us to establish the diagnosis of bronchial asthma. The increase in the maximum expiratory volume per second (VEMS) by 12% and 200 ml from the initial value after taking four short-acting bronchodilator puffs is suggestive of bronchial asth­ma. The ACT questionnaire is used to show whether the di­sease is well controlled therapeutically. Exposure to allergens, over­weight, gastroesophageal reflux disease, rhinosinusitis, na­sal polyposis and smoking are some of the comorbidities and trig­­gers of bronchial asthma crisis. In terms of treatment, asth­matic patients have inhaled de­vices that contain as the first line of treatment inhaled cor­ti­co­ste­roids to which a long-acting beta2-agonist is added. Choosing the right the­ra­py for each patient is made on the basis of five stages of treatment, depending on the symp­to­ma­to­logy of each in­di­vi­dual patient, the phenotype of asth­ma and the co­mor­bi­di­ties present. Patients with severe asth­ma benefit from tar­ge­ted biological therapy.","PeriodicalId":489459,"journal":{"name":"Medic.ro","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134888563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing the diagnosis of prostate malignancy 优化前列腺恶性肿瘤的诊断
Pub Date : 2023-01-01 DOI: 10.26416/med.154.4.2023.8712
Remus Şipoş, Emese Orban
The establishment of the National Cancer Registry and its implementation as a computer and information system will help to understand the real burden of cancer diseases in Romania and could be the foundation on which to design, implement and run prevention programs. Its emergence is due to the rise in cancer incidence and mortality and re­pre­sents the last step taken by the political decision-maker for the management of these pathologies. The need for clear re­cords began to be formulated from a legislative point of view as early as 1980 when, by order of the Ministry of Health, reporting of these pathologies was made com­pul­sory. Subsequently, in 2008, the establishment of Re­gio­nal Cancer Registries began. According to the re­gis­tered data, a re­port of the European Journal of Onco­logy high­lighted the doubling of the number of deaths caused by cancer diseases in Romania in 2018, compared to 2009. The cen­tra­lized data showed that prostate cancer ranked third when the incidence is analyzed in both sexes and second when the incidence ana­ly­sis refers only to the male sex. The true extent of pros­tate cancer can only be determined by early and correct di­ag­no­sis. This involves presenting the pa­tient to the doc­tor when symptoms appear which may be suggestive of po­ten­tially malignant prostate disease. Unfortunately, many in­for­ma­tion channels promote re­me­dies that relieve such symp­toms, remedies available both in pharmacies and through on­line orders, and this can delay the presentation to the doc­tor and, thus, the diagnosis.
国家癌症登记处的建立及其作为计算机和信息系统的实施将有助于了解罗马尼亚癌症疾病的真正负担,并可作为设计、实施和运行预防方案的基础。它的出现是由于癌症发病率和死亡率的上升,代表了政治决策者为管理这些病理所采取的最后一步。早在1980年,根据卫生部的命令,从立法角度开始制定明确记录的必要性,规定必须报告这些病症。随后,在2008年,开始建立区域癌症登记处。根据重新注册的数据,《欧洲肿瘤学杂志》(European Journal of oncology)的一份报告强调,2018年罗马尼亚因癌症导致的死亡人数比2009年翻了一番。集中数据显示,在男女发病率分析中,前列腺癌排在第三位,而在发病率分析中,仅指男性时,前列腺癌排在第二位。前列腺癌的真正程度只能通过早期和正确的诊断来确定。这包括当症状出现时将病人介绍给医生,这些症状可能暗示前列腺疾病可能是恶性的。不幸的是,许多医疗渠道都在宣传可以缓解这些症状的药物,这些药物在药店和在线订购中都有,这可能会延迟向医生提出,从而延误诊断。
{"title":"Optimizing the diagnosis of prostate malignancy","authors":"Remus Şipoş, Emese Orban","doi":"10.26416/med.154.4.2023.8712","DOIUrl":"https://doi.org/10.26416/med.154.4.2023.8712","url":null,"abstract":"The establishment of the National Cancer Registry and its implementation as a computer and information system will help to understand the real burden of cancer diseases in Romania and could be the foundation on which to design, implement and run prevention programs. Its emergence is due to the rise in cancer incidence and mortality and re­pre­sents the last step taken by the political decision-maker for the management of these pathologies. The need for clear re­cords began to be formulated from a legislative point of view as early as 1980 when, by order of the Ministry of Health, reporting of these pathologies was made com­pul­sory. Subsequently, in 2008, the establishment of Re­gio­nal Cancer Registries began. According to the re­gis­tered data, a re­port of the European Journal of Onco­logy high­lighted the doubling of the number of deaths caused by cancer diseases in Romania in 2018, compared to 2009. The cen­tra­lized data showed that prostate cancer ranked third when the incidence is analyzed in both sexes and second when the incidence ana­ly­sis refers only to the male sex. The true extent of pros­tate cancer can only be determined by early and correct di­ag­no­sis. This involves presenting the pa­tient to the doc­tor when symptoms appear which may be suggestive of po­ten­tially malignant prostate disease. Unfortunately, many in­for­ma­tion channels promote re­me­dies that relieve such symp­toms, remedies available both in pharmacies and through on­line orders, and this can delay the presentation to the doc­tor and, thus, the diagnosis.","PeriodicalId":489459,"journal":{"name":"Medic.ro","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134888976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Medic.ro
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1