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Evaluation of Drug-Drug Interactions in Patients Admitting to the Ear Nose and Throat Clinic 评估耳鼻喉科门诊住院病人的药物相互作用
Pub Date : 2024-07-08 DOI: 10.55895/sshs.1427187
Serkan Ceyhan, Sinem Gürcü
Introduction: Drug interactions are effects that change the effect of the drug and therefore on the patient, mostly due to the use of drugs together at the same or recent times. Drug interactions can cause serious consequences such as the development of adverse events, ineffectiveness of the treatment, or mortality. Materials and Methods: The prescriptions of 106 patients who applied to the ear, nose, and throat outpatient clinic between January and December 2021 were examined retrospectively. Results: 106 prescriptions were included in the study. Twelve major, 19 moderate, and 9 minor interactions were detected in 106 prescriptions. Conclusion: Although there are relatively few interactions compared to studies conducted with other patient groups, interactions can affect the clinical status of the patient. More attention should be paid to drug interactions in these patients, especially physicians and pharmacists.
简介药物相互作用是指改变药物疗效,进而改变对患者的影响,这主要是由于在同一时间或近期同时使用药物造成的。药物相互作用可导致严重后果,如出现不良反应、治疗无效或死亡。材料和方法:回顾性研究 2021 年 1 月至 12 月期间耳鼻喉科门诊 106 名患者的处方。结果研究共纳入 106 张处方。在 106 张处方中发现了 12 种严重相互作用、19 种中度相互作用和 9 种轻微相互作用。结论:虽然与针对其他患者群体的研究相比,相互作用相对较少,但相互作用会影响患者的临床状态。医生和药剂师应更加关注这些患者的药物相互作用。
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引用次数: 0
A LATE COMPLICATION OF BLUNT TRAUMA IN A CHILD: HEMORRHAGIC PANCREATIC PSEUDOCYST 儿童钝伤的晚期并发症:出血性胰腺假性囊肿
Pub Date : 2024-07-08 DOI: 10.55895/sshs.1477425
Burcu Akman, Ahmet Turan Kaya
Trauma is the most important cause of morbidity and mortality in the pediatric population. Pancreatic injury is relatively rare but has high morbidity and mortality when the diagnosis is delayed. However, diagnosis of pancreatic trauma is difficult. Ultrasound is limited for diagnosing pancreatic injury. Magnetic resonance imaging (MRI) is very useful for detecting direct and secondary signs of pancreatic injury and its complications such as abscess, fistula, pancreatitis, and pseudocyst. We presented a 10-year-old boy with a hemorrhagic pancreatic pseudocyst due to blunt trauma that happened a week ago. His laboratory findings showed elevated serum amylase and lipase levels. In abdominal ultrasonography, bilobular thick-walled fluid collections in the pancreatic parenchyma and peripancreatic location were observed. MRI showed hemorrhagic pseudocysts in the pancreas and pancreatic duct injury. The pseudocysts were treated by cysto-gastrostomy. Children should be carefully evaluated for pancreatic injury and late complications such as hemorrhagic pancreatic pseudocyst to reduce mortality after blunt trauma.
外伤是导致儿童发病和死亡的最重要原因。胰腺损伤相对罕见,但如果诊断不及时,发病率和死亡率都很高。然而,胰腺外伤的诊断非常困难。超声波对胰腺损伤的诊断有限。磁共振成像(MRI)对于检测胰腺损伤的直接和继发性体征及其并发症(如脓肿、瘘管、胰腺炎和假性囊肿)非常有用。我们接诊了一名 10 岁男孩,他一周前因钝性外伤导致出血性胰腺假性囊肿。他的化验结果显示血清淀粉酶和脂肪酶水平升高。腹部超声波检查发现,胰腺实质和胰腺周围有双叶厚壁积液。磁共振成像显示胰腺内有出血性假性囊肿和胰管损伤。假性囊肿通过膀胱-胃造口术进行了治疗。儿童应仔细评估胰腺损伤和出血性胰腺假性囊肿等晚期并发症,以降低钝性外伤后的死亡率。
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引用次数: 0
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Sabuncuoglu Serefeddin Health Sciences
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