Introduction: The dissolution of pulp tissue is an essential aspect of root canal treatment, as it aids in the removal of necrotic or infected tissue from the root canal, thereby reducing the microbial load. Aim: This in-vitro study aimed to compare the pulp tissue dissolving ability of three different pulp-dissolving agents with a 5.25% sodium hypochlorite (NaOCl) solution. Materials and Methods: 128 intact, non-carious extracted human single-rooted premolar teeth were selected and sectioned to harvest intact pulp tissue. Pulp tissue samples were randomly divided into four experimental groups (n=32) based on the pulp dissolving agent used: Group I (5.25% NaOCl solution), Group (5% Calcium hypochlorite solution), Group III (5.25% NaOCl gel) and Group IV (8% Papain gel). The initial weight of each sample was recorded and samples were exposed to specific pulp-dissolving agents for specified time intervals. The time required for complete dissolution of the pulp tissue was recorded for all samples till 120 mins. Results: The study analyzed the mean weight of pulp tissue in various groups, including Group I, Group II, Group III, and Group IV. After 30 minutes, complete dissolution of pulp tissue was evident in Group I, while Group II showed 0.0058 grams of remaining tissue after 30 minutes, 0.0040 grams after 60 minutes, and 0.0022 grams after 120 minutes. Group III showed 0.0072 grams of remaining tissue after 30 minutes, and Group IV showed 0.0075 grams of remaining tissue after 30 minutes, 60 minutes, 90 minutes, and 120 minutes. Conclusion: 5.25% NaOCl has the highest pulp tissue dissolution efficacy compared to other dissolving agents. Further clinical studies are warranted to validate these findings and assess the feasibility of these agents in clinical practice.
{"title":"A Comparative Evaluation of Pulp Tissue Dissolving Ability of Three Different Pulp Dissolving Agents With 5.25% Sodium Hypochlorite: An In-Vitro Study","authors":"Ganesh Kalandar, Manoj Ramugade, Kishor Sapkale, Abrar Sayed, Sapna Sonkurla","doi":"10.56501/intjorofacres.v7i2.903","DOIUrl":"https://doi.org/10.56501/intjorofacres.v7i2.903","url":null,"abstract":"Introduction: The dissolution of pulp tissue is an essential aspect of root canal treatment, as it aids in the removal of necrotic or infected tissue from the root canal, thereby reducing the microbial load. Aim: This in-vitro study aimed to compare the pulp tissue dissolving ability of three different pulp-dissolving agents with a 5.25% sodium hypochlorite (NaOCl) solution. Materials and Methods: 128 intact, non-carious extracted human single-rooted premolar teeth were selected and sectioned to harvest intact pulp tissue. Pulp tissue samples were randomly divided into four experimental groups (n=32) based on the pulp dissolving agent used: Group I (5.25% NaOCl solution), Group (5% Calcium hypochlorite solution), Group III (5.25% NaOCl gel) and Group IV (8% Papain gel). The initial weight of each sample was recorded and samples were exposed to specific pulp-dissolving agents for specified time intervals. The time required for complete dissolution of the pulp tissue was recorded for all samples till 120 mins. Results: The study analyzed the mean weight of pulp tissue in various groups, including Group I, Group II, Group III, and Group IV. After 30 minutes, complete dissolution of pulp tissue was evident in Group I, while Group II showed 0.0058 grams of remaining tissue after 30 minutes, 0.0040 grams after 60 minutes, and 0.0022 grams after 120 minutes. Group III showed 0.0072 grams of remaining tissue after 30 minutes, and Group IV showed 0.0075 grams of remaining tissue after 30 minutes, 60 minutes, 90 minutes, and 120 minutes. Conclusion: 5.25% NaOCl has the highest pulp tissue dissolution efficacy compared to other dissolving agents. Further clinical studies are warranted to validate these findings and assess the feasibility of these agents in clinical practice.","PeriodicalId":496124,"journal":{"name":"International Journal of Orofacial Research","volume":"30 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135725753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-05DOI: 10.56501/intjorofacres.v7i2.887
Pradnya Dattatraya Kadam, Mala Dixit Baburaj, Bhalchandra Thorat
Gingival overgrowth was a side effect of several different drug classes, including anticonvulsants, immunosuppressants, and calcium channel blockers. Extracellular collagenous matrix components accumulate together with varying degrees of inflammation to describe it. The anti-epileptic phenytoin is one of the main medications linked to gingival overgrowth. It affects gingival tissues by changing the metabolism of extracellular matrix. This paper aims to present a case report on non-surgical management of phenytoin drug induced gingival enlargement.
{"title":"Drug Induced Gingival Enlargement: Non-Surgical Management","authors":"Pradnya Dattatraya Kadam, Mala Dixit Baburaj, Bhalchandra Thorat","doi":"10.56501/intjorofacres.v7i2.887","DOIUrl":"https://doi.org/10.56501/intjorofacres.v7i2.887","url":null,"abstract":"Gingival overgrowth was a side effect of several different drug classes, including anticonvulsants, immunosuppressants, and calcium channel blockers. Extracellular collagenous matrix components accumulate together with varying degrees of inflammation to describe it. The anti-epileptic phenytoin is one of the main medications linked to gingival overgrowth. It affects gingival tissues by changing the metabolism of extracellular matrix. This paper aims to present a case report on non-surgical management of phenytoin drug induced gingival enlargement.","PeriodicalId":496124,"journal":{"name":"International Journal of Orofacial Research","volume":"30 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135725755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The calcifying odontogenic cyst (COC), discovered in 1962, is a rare developmental odontogenic cyst clinically present as slow-growing swelling mainly in the anterior portion of the jaws, generally present in the second and sixth decades of life. It accounts for 0.3%–0.8% of odontogenic cysts. COC showed variations in clinical and radiographic features that are not pathognomic, whereas histomorphology forms exist in 3 patterns: benign cystic, solid (neoplastic), and aggressive (malignant) forms. The radiograph shows well-defined radiolucency with irregular masses, while the histopathologic features include a cystic lining with characteristic “Ghost” cells and immunohistochemical reactions positive for various enamel proteins.
{"title":"Calcifying Odontogenic Cyst: An Enigma","authors":"Amisha Jain, Himanshu Dhanodkar, Anjali Shujalpurkar, Gauri Motiwale","doi":"10.56501/intjorofacres.v7i2.895","DOIUrl":"https://doi.org/10.56501/intjorofacres.v7i2.895","url":null,"abstract":"The calcifying odontogenic cyst (COC), discovered in 1962, is a rare developmental odontogenic cyst clinically present as slow-growing swelling mainly in the anterior portion of the jaws, generally present in the second and sixth decades of life. It accounts for 0.3%–0.8% of odontogenic cysts. COC showed variations in clinical and radiographic features that are not pathognomic, whereas histomorphology forms exist in 3 patterns: benign cystic, solid (neoplastic), and aggressive (malignant) forms. The radiograph shows well-defined radiolucency with irregular masses, while the histopathologic features include a cystic lining with characteristic “Ghost” cells and immunohistochemical reactions positive for various enamel proteins.","PeriodicalId":496124,"journal":{"name":"International Journal of Orofacial Research","volume":"30 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135725754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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