Pub Date : 2023-10-03DOI: 10.14229/onco.2023.10.03.002
Joe Woolery
When global health crises such as the COVID-19 pandemic and HIV/AIDS epidemic occur, drug developers and researchers have an opportunity to highlight the benefits of implementing international clinical development plans to make treatments available as quickly as possible for patients around the world. However, when these public crises are not a factor, organizations typically wait until a product is nearing its approval stage before planning for and developing an international strategy.
{"title":"Think Globally, Act Globally: The Key Role Global Hubs Play in Oncological Drug Development","authors":"Joe Woolery","doi":"10.14229/onco.2023.10.03.002","DOIUrl":"https://doi.org/10.14229/onco.2023.10.03.002","url":null,"abstract":"When global health crises such as the COVID-19 pandemic and HIV/AIDS epidemic occur, drug developers and researchers have an opportunity to highlight the benefits of implementing international clinical development plans to make treatments available as quickly as possible for patients around the world. However, when these public crises are not a factor, organizations typically wait until a product is nearing its approval stage before planning for and developing an international strategy.","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135689511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-10-02DOI: 10.14229/onco.2023.10.02.001
Emily Carlucci
Loneliness and depression significantly impact the psychological and physical well-being of older individuals diagnosed with cancer or hematological diseases. This paper reviews the intricate relationship between loneliness, depression, and their effects on older adults’ health outcomes. Through an analysis of published peer-reviewed journal articles, this paper explores the complex interactions between these psychological states and their implications for treatment adherence, quality of life, and overall health.
{"title":"The Interconnectedness of Loneliness and Depression on Older Individuals Diagnosed with Cancer","authors":"Emily Carlucci","doi":"10.14229/onco.2023.10.02.001","DOIUrl":"https://doi.org/10.14229/onco.2023.10.02.001","url":null,"abstract":"Loneliness and depression significantly impact the psychological and physical well-being of older individuals diagnosed with cancer or hematological diseases. This paper reviews the intricate relationship between loneliness, depression, and their effects on older adults’ health outcomes. Through an analysis of published peer-reviewed journal articles, this paper explores the complex interactions between these psychological states and their implications for treatment adherence, quality of life, and overall health.","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135792801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-20DOI: 10.14229/onco.2023.09.20.010
Danielle Garcia
As October draws near, the annual Breast Cancer Awareness Month comes to the forefront, shedding light on the significant impact of breast cancer on people’s lives, it may be appropriate to consider the unequal access to care. Especially since, alarmingly, breast cancer continues to affect a significant number of individuals in the US, making it a prevalent health concern.
{"title":"October Breast Cancer Awareness Month: Emphasizing Equity in Access to Early Detection","authors":"Danielle Garcia","doi":"10.14229/onco.2023.09.20.010","DOIUrl":"https://doi.org/10.14229/onco.2023.09.20.010","url":null,"abstract":"As October draws near, the annual Breast Cancer Awareness Month comes to the forefront, shedding light on the significant impact of breast cancer on people’s lives, it may be appropriate to consider the unequal access to care. Especially since, alarmingly, breast cancer continues to affect a significant number of individuals in the US, making it a prevalent health concern.","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136313546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-18DOI: 10.14229/onco.2023.09.18.011
Jennifer Goldenberg Klarer
Gene therapy is emerging as a potential cure for those battling sickle cell disease, offering optimism for those affected by this debilitating condition. For this promise to be realized, however, significant barriers to access must be mitigated. In this article, we delve into challenges faced by vulnerable populations in accessing cell and gene therapies and explore potential solutions.
{"title":"Breaking Barriers to Access: Empowering Vulnerable Populations with Cell and Gene Therapy","authors":"Jennifer Goldenberg Klarer","doi":"10.14229/onco.2023.09.18.011","DOIUrl":"https://doi.org/10.14229/onco.2023.09.18.011","url":null,"abstract":"Gene therapy is emerging as a potential cure for those battling sickle cell disease, offering optimism for those affected by this debilitating condition. For this promise to be realized, however, significant barriers to access must be mitigated. In this article, we delve into challenges faced by vulnerable populations in accessing cell and gene therapies and explore potential solutions.","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135207000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-18DOI: 10.14229/onco.2023.09.18.010
Peter Hofland
The role of microbes that live on human surfaces — generally referred to as microbiota – in cancer formation, diagnosis, prognosis, and treatment have long been disputed.[1]. However, researchers agree that microbial communities, formed by bacteria, archaea, fungi, protozoa and viruses interact with our own physiology and are known to play important roles in human health and disease.
{"title":"Understanding the True Impact of Microbiota on Cancer Development and Treatment","authors":"Peter Hofland","doi":"10.14229/onco.2023.09.18.010","DOIUrl":"https://doi.org/10.14229/onco.2023.09.18.010","url":null,"abstract":"The role of microbes that live on human surfaces — generally referred to as microbiota – in cancer formation, diagnosis, prognosis, and treatment have long been disputed.[1]. However, researchers agree that microbial communities, formed by bacteria, archaea, fungi, protozoa and viruses interact with our own physiology and are known to play important roles in human health and disease.","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135151680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-16DOI: 10.14229/onco.2023.09.16.010
Peter Hofland
Patients who face language barriers are more likely to consume more healthcare services but are also experiencing more adverse events. These studies show that most of these increased costs were attributable to patients requiring and receiving interpreter services, while medical errors resulting in and adverse events occurred more frequently among patients with limited proficiency in English than among those who were proficient in English
{"title":"Language Barriers and the Impact on Cancer Care","authors":"Peter Hofland","doi":"10.14229/onco.2023.09.16.010","DOIUrl":"https://doi.org/10.14229/onco.2023.09.16.010","url":null,"abstract":"Patients who face language barriers are more likely to consume more healthcare services but are also experiencing more adverse events. These studies show that most of these increased costs were attributable to patients requiring and receiving interpreter services, while medical errors resulting in and adverse events occurred more frequently among patients with limited proficiency in English than among those who were proficient in English","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135306522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-12DOI: 10.14229/onco.2023.09.12.010
Peter Hofland
Intensity-modulated radiation therapy, also known as IMRT, should be utilized for treatment of locally advanced Non-Small Cell Lung Cancer (NSCLC) to reduce the risk of severe pulmonary toxicity and radiation exposure to the heart.
{"title":"Long-term Outcomes of Radiation Techniques for the Treatment of Locally Advanced NSCLC","authors":"Peter Hofland","doi":"10.14229/onco.2023.09.12.010","DOIUrl":"https://doi.org/10.14229/onco.2023.09.12.010","url":null,"abstract":"Intensity-modulated radiation therapy, also known as IMRT, should be utilized for treatment of locally advanced Non-Small Cell Lung Cancer (NSCLC) to reduce the risk of severe pulmonary toxicity and radiation exposure to the heart.","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135886686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-11DOI: 10.14229/onco.2023.09.02.011
Bryan Oronsky, Babak Alizadeh
At one point only a few short years ago several more were in the race to be approved for severe oral mucositis (SOM), which refers to sores or ulcers that develop in the mouth and throat. SOM is the most serious and common complication from the management of head and neck cancer, a highly curable cancer if detected early and treated fully.
{"title":"Severe Oral Mucositis: Companies Put Their Money where the Mouth is and Vie for a Marketshare","authors":"Bryan Oronsky, Babak Alizadeh","doi":"10.14229/onco.2023.09.02.011","DOIUrl":"https://doi.org/10.14229/onco.2023.09.02.011","url":null,"abstract":"At one point only a few short years ago several more were in the race to be approved for severe oral mucositis (SOM), which refers to sores or ulcers that develop in the mouth and throat. SOM is the most serious and common complication from the management of head and neck cancer, a highly curable cancer if detected early and treated fully.","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135982344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-11DOI: 10.14229/onco.2023.09.01.010
Hilton M. Hudson
Nineteen percent of the nation’s nursing workforce was 65 years of age or older as of 2020, making this the largest age group within the nursing profession. One-fifth of nurses are likely to retire by 2027, setting the stage for a dramatic transition in which the most experienced nurses leave the healthcare profession and recently graduated nurses begin taking their place.
{"title":"Recruiting and Retaining Nurses: A Critical Challenge Facing the Healthcare Industry","authors":"Hilton M. Hudson","doi":"10.14229/onco.2023.09.01.010","DOIUrl":"https://doi.org/10.14229/onco.2023.09.01.010","url":null,"abstract":"Nineteen percent of the nation’s nursing workforce was 65 years of age or older as of 2020, making this the largest age group within the nursing profession. One-fifth of nurses are likely to retire by 2027, setting the stage for a dramatic transition in which the most experienced nurses leave the healthcare profession and recently graduated nurses begin taking their place.","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135938330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-15DOI: 10.14229/onco.2023.02.15.001
Craig Eagle
What if a simple blood draw taken during a routine visit to the doctor for a check-up or a flu shot could allow us to identify specific cancers at an early stage, when they are the most treatable? What if blood tests could help the cancer care team improve patient care at every step of the patient’s journey—from detection to treatment selection to response and recurrence monitoring?
{"title":"Liquid Biopsy: Unlocking New Insights to Help Improve Outcomes for Cancer Patients","authors":"Craig Eagle","doi":"10.14229/onco.2023.02.15.001","DOIUrl":"https://doi.org/10.14229/onco.2023.02.15.001","url":null,"abstract":"What if a simple blood draw taken during a routine visit to the doctor for a check-up or a flu shot could allow us to identify specific cancers at an early stage, when they are the most treatable? What if blood tests could help the cancer care team improve patient care at every step of the patient’s journey—from detection to treatment selection to response and recurrence monitoring?","PeriodicalId":496622,"journal":{"name":"Onco'zine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135683621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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