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Validity and Reliability of the Turkish Version of the Patient-Reported Impact of Spasticity Measure in Multiple Sclerosis 多发性硬化症患者自述痉挛影响测量土耳其版的有效性和可靠性
Pub Date : 2024-07-22 DOI: 10.7224/1537-2073.2023-056
Gizem Yağmur Yalçın, Cansu Polat Dünya, Kubra Yeni, M. Kürtüncü, Z. Tulek, Tuncay Gündüz, M. Eraksoy
We aimed to evaluate the validity and reliability of the Turkish version of the Patient-Reported Impact of Spasticity Measure (PRISM-TR). Expert opinions and the forward-back translation method were used for linguistic validation. Cronbach α and test-retest analysis were performed for reliability analysis. Correlations between the PRISM-TR and the Modified Ashworth Scale (MAS), the Numerical Rating Scale (NRS), and the Expanded Disability Status Scale (EDSS) were assessed. A total of 206 individuals with multiple sclerosis (MS; 139 women; mean age, 47.7 ± 11.3 years; mean EDSS score, 5.2 ± 1.5) who had not had a relapse in the previous 3 months were included in the study. Test-retest correlation coefficients were high for all subdimensions of the scale (0.95-0.99). All Cronbach α values for the PRISM-TR subdimensions, except for Positive Impact, were likewise quite high (0.85-0.94). PRISM-TR subscale scores were correlated with MAS, NRS, and EDSS scores (P < .001). PRISM-TR is a valid and reliable scale for use with Turkish individuals with MS. It is simple to use in the clinic and can be helpful in detecting patients’ spasticity early in the disease course.
我们旨在评估土耳其语版患者报告的痉挛影响测量(PRISM-TR)的有效性和可靠性。 语言验证采用了专家意见和向前向后翻译法。信度分析采用了 Cronbach α 和重复测试分析。评估了 PRISM-TR 与改良阿什沃斯量表(MAS)、数字评定量表(NRS)和残疾状况扩展量表(EDSS)之间的相关性。 共有 206 名多发性硬化症患者(MS;139 名女性;平均年龄(47.7 ± 11.3)岁;平均 EDSS 评分(5.2 ± 1.5)在过去 3 个月内未复发。量表所有子维度的测试-重测相关系数都很高(0.95-0.99)。除积极影响外,PRISM-TR 所有子量表的 Cronbach α 值同样很高(0.85-0.94)。PRISM-TR 子量表得分与 MAS、NRS 和 EDSS 分数相关(P < .001)。 PRISM-TR 是一种有效、可靠的量表,适用于土耳其多发性硬化症患者。该量表在临床上使用简单,有助于在病程早期发现患者的痉挛症状。
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引用次数: 0
Investigating the Impact of Polypharmacy and Anticholinergic Medication Burden on Objective Cognitive Performance in Adults With Multiple Sclerosis 调查多药治疗和抗胆碱能药物负担对成人多发性硬化症患者客观认知能力的影响
Pub Date : 2024-03-01 DOI: 10.7224/1537-2073.2023-014
J. Huebner, J. Robichaud, Julia S. Cozart, Crystal Burkhardt, S. Lynch, J. M. Bruce
ACTIVITY AVAILABLE ONLINE: To access the article and evaluation online, go to https://www.highmarksce.com/mscare. TARGET AUDIENCE: The target audience for this activity is physicians, advanced practice clinicians, nursing professionals, pharmacists, researchers, and other health care providers involved in the study and management of patients with multiple sclerosis (MS). LEARNING OBJECTIVE: Review current research, including limitations, of the potential cognitive impacts of polypharmacy and anticholinergic burden in individuals with MS. Evaluate potential cognitive risks associated with polypharmacy and anticholinergic burden using tools such as the Drug Burden Index to guide decision-making in the development of comprehensive treatment plans. ACCREDITATION: In support of improving patient care, this activity has been planned and implemented by the Consortium of Multiple Sclerosis Centers (CMSC) and Intellisphere, LLC. The CMSC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the health care team. This activity was planned by and for the health care team, and learners will receive 1.0 Interprofessional Continuing Education (IPCE) credit for learning and change. PHYSICIANS: The CMSC designates this journal-based activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. NURSES: The CMSC designates this enduring material for 1.0 contact hour of nursing continuing professional development (NCPD) (1.0 in the area of pharmacology). PHARMACISTS: This knowledge-based activity (UAN JA4008165-9999-24-004-H01-P) qualifies for 1.0 contact hour (.01 CEUs) of continuing pharmacy education credit. PAS: The CMSC has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. The activity is designated for 1.0 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation. PSYCHOLOGISTS: This activity is awarded 1.0 CE credit. DISCLOSURES: It is the policy of the Consortium of Multiple Sclerosis Centers to mitigate all relevant financial disclosures from planners, faculty, and other persons that can affect the content of this CE activity. For this activity, all relevant disclosures have been mitigated. Francois Bethoux, MD, editor in chief of the International Journal of MS Care (IJMSC), has served as physician planner for this activity. He has disclosed no relevant financial relationships. Alissa Mary Willis, MD, associate editor of IJMSC, has disclosed not relevant financial relationships. Sharon G. Lynch, MD, has disclosed financial relationships with Atara Biotherapeutics, Biogen, Bristol Myers Squibb, Immunic, N
临床医生或其他医疗保健专业人员在使用本出版物中讨论的任何药物、诊断程序或治疗方法之前,应首先对患者的病情进行评估,考虑可能存在的禁忌症或风险,查看任何适用的制造商产品信息,并将任何治疗方法与其他权威机构的建议进行比较。
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引用次数: 0
The Impact of COVID-19 on the Employment of People With Multiple Sclerosis: A Multi-Methods Study COVID-19 对多发性硬化症患者就业的影响:多方法研究
Pub Date : 2024-01-22 DOI: 10.7224/1537-2073.2023-049
Blanca De Dios Pérez, Charlotte Pritchard, Katie Powers, Roshan das Nair, Nikos Evangelou, Helen Ford, Emma Tallantyre, Ruth Dobson, Kathryn Radford
The COVID-19 pandemic led to approximately half of the working population in the United Kingdom being unable to work temporarily. This study aims to understand the employment needs and experiences of people with multiple sclerosis (MS) in the UK during this period. Multiple methods were used, including an online survey and follow-up interviews with people with MS who were employed prior to the start of the pandemic restrictions in March 2020. The online survey was completed by 101 eligible participants and we interviewed 15 of them for qualitative data in the follow-up. Survey data indicated that the work experience of people with MS improved during the pandemic because they were allowed to work from home. However, participants experienced increased feelings of anxiety and loneliness. From the interviews, we extracted 5 themes: (1) the benefits of working from home; (2) the challenges of working during the COVID-19 pandemic; (3) the relevance of managers; (4) returning to “normal”; and (5) the need for vocational support. The pandemic showed that MS symptom management was improved by work flexibility (eg, working from home, breaks, flexible working hours); for people with MS, these accommodations improved both their ability to work and their self-perceived productivity. Future research should explore the support needs of people with MS who work remotely and determine whether pandemic-influenced work accommodations are sustainable over time.
COVID-19 大流行导致英国大约一半的工作人口暂时无法工作。本研究旨在了解英国多发性硬化症(MS)患者在此期间的就业需求和经历。 研究采用了多种方法,包括在线调查和对 2020 年 3 月大流行限制开始前已就业的多发性硬化症患者进行跟踪采访。 101 名符合条件的参与者完成了在线调查,我们对其中 15 人进行了后续访谈,以获得定性数据。调查数据显示,在大流行期间,多发性硬化症患者的工作体验有所改善,因为他们可以在家工作。然而,参与者的焦虑感和孤独感却有所增加。我们从访谈中提取了 5 个主题:(1)在家工作的好处;(2)在 COVID-19 大流行期间工作所面临的挑战;(3)管理者的相关性;(4)回归 "正常";以及(5)对职业支持的需求。 大流行表明,灵活的工作方式(如在家工作、休息、灵活的工作时间)可改善多发性硬化症的症状管理;对于多发性硬化症患者来说,这些便利措施既提高了他们的工作能力,也提高了他们自我感觉的工作效率。未来的研究应探讨远程工作的多发性硬化症患者的支持需求,并确定受大流行病影响的工作便利是否可长期持续。
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引用次数: 0
Common Social and Health Disparities Contribute to Racial Differences in Ambulatory Impairment in Multiple Sclerosis 共同的社会和健康差异导致多发性硬化症患者行动障碍的种族差异
Pub Date : 2024-01-01 DOI: 10.7224/1537-2073.2023-004
F. Briggs, Erika S. Trapl, F. Mateen, Alessandro De Nadai, Devon S. Conway, Douglas D. Gunzler
ACTIVITY AVAILABLE ONLINE: To access the article and evaluation online, go to https://www.highmarksce.com/mscare. TARGET AUDIENCE: The target audience for this activity is physicians, advanced practice clinicians, nursing professionals, social workers, and other health care providers involved in the management of patients with multiple sclerosis (MS). LEARNING OBJECTIVE: Describe the extent to which common social and health disparities contribute to racial differences in ambulatory impairment in MS. Recognize the importance of distinguishing mediators from confounders in multivariable regression models. ACCREDITATION: In support of improving patient care, this activity has been planned and implemented by the Consortium of Multiple Sclerosis Centers (CMSC) and Intellisphere, LLC. The CMSC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the health care team. This activity was planned by and for the health care team, and learners will receive .5 Interprofessional Continuing Education (IPCE) credit for learning and change. PHYSICIANS: The CMSC designates this journal-based activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. NURSES: The CMSC designates this enduring material for .5 contact hour of nursing continuing professional development (NCPD) (none in the area of pharmacology). PSYCHOLOGISTS: This activity is awarded .5 CE credit. SOCIAL WORKERS: As a Jointly Accredited Organization, the CMSC is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit. Social workers completing this course receive .5 general continuing education credits. DISCLOSURES: It is the policy of the Consortium of Multiple Sclerosis Centers to mitigate all relevant financial disclosures from planners, faculty, and other persons that can affect the content of this CE activity. For this activity, all relevant disclosures have been mitigated. Francois Bethoux, MD, editor in chief of the International Journal of MS Care (IJMSC), has served as physician planner for this activity. He has disclosed no relevant financial relationships. Alissa Mary Willis, MD, associate editor of IJMSC, has disclosed not relevant financial relationships. Authors Farren B.S. Briggs, PhD, ScM; Farrah J. Mateen, MD, PhD; Devon Conway, MD, MS; Alessandro de Nadai, PhD; Erika S. Trapl, PhD; and Douglas D. Gunzler, PhD, have disclosed no relevant financial relationships. The staff at IJMSC, CMSC, and Intellisphere, LLC who are in a positio
在线活动:要在线访问文章和评估,请访问 https://www.highmarksce.com/mscare。目标受众:本活动的目标受众是参与多发性硬化症(MS)患者管理的医生、高级临床医师、护理专业人员、社会工作者和其他医疗服务提供者。学习目标:描述常见的社会和健康差异在何种程度上导致了多发性硬化症行动障碍的种族差异。认识在多变量回归模型中区分中介因素和混杂因素的重要性。认证:为支持改善患者护理,多发性硬化症中心联盟(CMSC)和 Intellisphere, LLC 计划并实施了这项活动。多发性硬化症中心联盟由继续医学教育认证委员会 (ACCME)、药学教育认证委员会 (ACPE) 和美国护士资格认证中心 (ANCC) 联合认证,为医疗团队提供继续教育。该活动由医疗团队策划并为医疗团队服务,学习者将获得 0.5 个跨专业继续教育 (IPCE) 学分,用于学习和改变。医生:CMSC 指定本期刊活动最多可获得 0.5 个 AMA PRA 1 类学分™。医生只能申请与其参与活动程度相称的学分。护士:CMSC 指定本持久材料可获得 0.5 个护理继续职业发展 (NCPD) 接触小时(无药理学领域)。心理学家:本活动可获得 0.5 CE 学分。社会工作者:作为联合认证组织,CMSC 经社会工作委员会协会(Association of Social Work Boards, ASWB)批准,可提供社会工作继续教育(Approved Continuing Education, ACE)项目。该计划批准的是组织,而非个别课程。监管委员会是接受继续教育学分课程的最终权威机构。完成此课程的社会工作者可获得 0.5 个普通继续教育学分。披露:多发性硬化症中心联盟的政策是减少策划者、教师和其他可能影响本继续教育活动内容的人员披露的所有相关财务信息。对于本次活动,所有相关披露均已减少。国际多发性硬化症护理杂志》(International Journal of MS Care, IJMSC)主编、医学博士 Francois Bethoux 担任本次活动的医生策划人。他未披露任何相关财务关系。艾丽莎-玛丽-威利斯(Alissa Mary Willis)医学博士是《国际多发性硬化症护理杂志》(IJMSC)的副主编,她未披露任何相关财务关系。作者 Farren B.S. Briggs(医学博士)、Farrah J. Mateen(医学博士)、Devon Conway(医学博士)、Alessandro de Nadai(医学博士)、Erika S. Trapl(医学博士)和 Douglas D. Gunzler(医学博士)未披露任何相关财务关系。IJMSC、CMSC 和 Intellisphere, LLC 公司中能够影响内容的员工均未披露任何相关财务关系。CMSC 继续教育主任、DNP、NP 劳里-斯卡德(Laurie Scudder)是本次活动的策划者和审核者。她未披露任何相关财务关系。参与方式:发布日期:发布日期:2024 年 1 月 1 日;学分有效期:2025 年 1 月 1 日:为获得 CE 学分,参与者必须(1)查看继续教育信息,包括学习目标和作者披露。(2)学习教育内容。(3)完成评估,评估结果可从 https://www.highmarksce.com/mscare 网站获取。成功完成评估后可获得学分证明。参加本活动不收取任何费用。披露无标签使用:本教育活动可能包含对未经 FDA 批准的药剂的已公布和/或研究用途的讨论。CMSC 和 Intellisphere, LLC 不建议在标示适应症之外使用任何药物。教育活动中表达的观点仅代表教员的意见,并不一定代表 CMSC 或 Intellisphere, LLC 的观点。免责声明:参与者有责任使用新获得的信息来提高患者的治疗效果和自身的专业发展。本活动中提供的信息无意作为患者管理的指南。临床医生或其他医疗保健专业人员在使用本出版物中讨论的任何药物、诊断程序或治疗方法时,应首先评估患者的病情,考虑可能的禁忌症或风险,查看任何适用的制造商产品信息,并将任何治疗方法与其他权威机构的建议进行比较。
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引用次数: 0
Abstracts from the 34th Annual Meeting of the Consortium of Multiple Sclerosis Centers 多发性硬化症中心联盟第 34 届年会摘要
Pub Date : 2020-05-01 DOI: 10.7224/1537-2073-22.s2.1
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引用次数: 0
期刊
International Journal of MS Care
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