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Indonesian Journal of Rheumatology最新文献

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Interventional Intensive Care in Postoperative Period of Gastric Surgical Repair Due to Perforated Peptic Ulcer Disease : A Case Report 穿孔性消化性溃疡胃手术修补术后的介入性重症监护:病例报告
Pub Date : 2024-05-07 DOI: 10.37275/ijr.v14i3.295
Liliriawati Ananta Kahar
Introduction: Perforated peptic ulcer is the most common indication for emergency gastric surgery. good management of postoperative peptic ulcer perforation patients in the ICU will reduce patient mortality rates. Case presentation A 76-year-old male patient presented with a major complaint of pain throughout the abdomen that had worsened since 1 day, the abdominal pain had been felt for 4 days before admission. The patient had a history of painkiller drug consumption routinely for 3 years. The patient’s vital signs were normal, with a qSOFA score 1 and a VAS score 5. Abdominal physical examination showed the abdominal distended, no visible contour and no visible peristaltic, decreased bowel sound, and there is tenderness and rebound tenderness at the whole abdomen Patient was taken up for emergency laparostomy, then the patient underwent diagnostic laparoscopic in an elective setting with intraoperative findings of gastric perforation, then patient continued with the gastric repair. In the postoperative period, the patient was treated in the ICU of Dr. M. Djamil General Hospital. Conclusion: Intensive care management for post-gastric repair surgery patients is generally the same as for other abdominal surgery patients. The intensive care management needs comprehensive treatment, starting from oxygen therapy, monitoring, analgesia, fluid therapy, antibiotic therapy, glycemic control, and nasogastric tube nutrition.
导言:消化性溃疡穿孔是急诊胃部手术最常见的指征。在重症监护病房对消化性溃疡穿孔患者进行良好的术后管理将降低患者的死亡率。病例介绍 一位 76 岁的男性患者以全腹疼痛为主诉,入院 1 天后疼痛加剧,入院前腹痛已持续 4 天。患者有 3 年常规服用止痛药的病史。患者生命体征正常,qSOFA评分1分,VAS评分5分。腹部体格检查显示腹部胀满,无明显轮廓,无明显蠕动,肠鸣音减弱,全腹有压痛和反跳痛 患者被送入急诊腹腔镜手术室,随后患者在择期环境下接受了诊断性腹腔镜手术,术中发现胃穿孔,随后患者继续进行胃修补术。术后,患者在 M. Djamil 医生综合医院重症监护室接受治疗。结论胃修补术后患者的重症监护管理一般与其他腹部手术患者相同。重症监护管理需要从氧疗、监测、镇痛、液体治疗、抗生素治疗、血糖控制和鼻胃管营养等方面入手,进行综合治疗。
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引用次数: 0
Comparative Analysis of the Inhibitory Efficacy of 50% and 80% Concentrations of Rambutan Seed Extract (Nephelium lappaceum L.) on the Growth of Candida albicans 红毛丹籽提取物(Nephelium lappaceum L.)50%和80%浓度对白色念珠菌生长的抑制作用比较分析
Pub Date : 2024-01-27 DOI: 10.37275/ijr.v14i3.284
Cindy Denhara Wijaya, Daryono, Rasyika Adani
Introduction. Denture stomatitis is a prevalent issue among those who wear dentures, and it is caused by Candida albicans. Ketoconazole, an azole antifungal medication, is commonly employed to treat denture stomatitis. However, it is important to note that the usage of this agent might lead to hepatotoxicity and the development of resistance. The objective of the study was to assess the inhibitory efficacy of rambutan seed extract (Nephelium lappaecum L.) at concentrations of 50% and 80% on the proliferation of Candida albicans. Methods. This research employs a laboratory experiment using a design that includes a post-test only control group. The specimen is an uncontaminated culture isolation of Candida albicans. This study had four distinct groups: rambutan seed extract concentrations of 50% and 80%, a positive control group, and a negative control group. Each group was reproduced six times. Using digital calipers to measure the diameter of resistance. Upon completion of data collection, the acquired data was subsequently subjected to analysis utilizing one-way ANOVA and post hoc LSD statistical testing. Results. The research findings indicate that the average ± standard deviation inhibitory diameter of rambutan seed extract was 50%, 80%, and the positive control for the growth of Candida albicans was 8.68 ± 0.585; 12.38±0.505; 22.43 ± 0.809 mm, respectively. In contrast, the negative control (DMSO) did not exhibit any inhibitory effects. The one-way ANOVA test revealed a statistically significant difference in the mean inhibitory diameter of rambutan seed extract at concentrations of 50% and 80% on the growth of Candida albicans (p=0.000; p?0.05). The findings of the LSD post hoc test indicated a significant difference in inhibitory power between the 50% and 80% concentrations of rambutan seed extract, as well as between these concentrations and both the positive and negative controls. Additionally, there was a significant difference in the growth of Candida albicans between the 50% and 80% concentrations of rambutan seed extract (p?0.05). Conclusion. The research findings indicate that the extract derived from rambutan seeds effectively inhibits the development of Candida albicans. An 80% concentration is the optimal concentration for maximum effectiveness.
导言假牙口腔炎是佩戴假牙的人中普遍存在的问题,它是由白色念珠菌引起的。酮康唑是一种唑类抗真菌药物,通常用于治疗义齿口腔炎。但需要注意的是,使用这种药物可能会导致肝毒性和耐药性的产生。本研究的目的是评估红毛丹种子提取物(Nephelium lappaecum L.)浓度为50%和80%时对白色念珠菌增殖的抑制功效。研究方法本研究采用实验室实验设计,其中包括一个测试后对照组。标本是未受污染的白色念珠菌培养分离物。这项研究有四个不同的组:红毛丹籽提取物浓度为 50%和 80%的组、阳性对照组和阴性对照组。每组重复六次。使用数字卡尺测量阻力直径。数据收集完成后,利用单因素方差分析和事后 LSD 统计检验对所获数据进行分析。结果研究结果表明,红毛丹籽提取物对白色念珠菌生长的平均抑制直径(±标准偏差)分别为 8.68 ± 0.585 毫米、12.38±0.505 毫米和 22.43 ± 0.809 毫米,分别为 50%、80% 和阳性对照。相比之下,阴性对照(二甲基亚砜)没有显示出任何抑制作用。单因素方差分析检验表明,红豆种子提取物浓度为 50%和 80%时,对白色念珠菌生长的平均抑制直径差异有统计学意义(P=0.000;P?)LSD post hoc 检验结果表明,红毛丹籽提取物浓度为 50%和 80%时,其抑制能力有显著差异;浓度为 50%和 80%时,其抑制能力与阳性对照组和阴性对照组也有显著差异。此外,50%和 80% 浓度的红毛丹籽提取物对白色念珠菌的生长也有显著差异(p?0.05)。结论研究结果表明,红毛丹籽提取物能有效抑制白色念珠菌的生长。80%的浓度是发挥最大功效的最佳浓度。
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引用次数: 0
The Relationship between the Level of Knowledge of Consuming Donuts and Sweet Gum as Cariogenic Foods and the Occurrence of Dental Caries in Class 12 Students at Cahaya Medan High School 卡哈亚棉兰中学 12 年级学生对甜甜圈和甜口香糖是致龋食品的认知水平与龋齿发生率之间的关系
Pub Date : 2024-01-16 DOI: 10.37275/ijr.v14i3.280
Susiani Tarigan, Firdha Muharraran, Putri Angelia Pardede
Introduction: Food and drinks taste sweet and sticky, which can trigger dental caries. The increasing number of dental caries for children shows the need for optimal treatment in increasing their knowledge. The aim of the research is to find a relationship between the level of knowledge of consuming donuts and sweet chewing gum as cariogenic foods on experiencing dental caries for grade 12 students at Cahaya Medan High School. Methods: Data collection using questionnaires and checking teeth. Data were analyzed using statistical tests Kruskal-Wallis. This type of research is an analytical survey through design cross sectional. Results: The research results showed that the majority of the level of knowledge of consuming donuts and sweet chewing gum as cariogenic foods in the sample was sufficient with the average DMFT score being .63 ± 2.723. Conclusion: it can be concluded that the better the level of knowledge about consuming donuts and sweet chewing gum as cariogenic foods, the lower the dental caries.
简介食物和饮料味道甜糯,容易引发龋齿。儿童龋齿数量的不断增加表明,有必要通过增加他们的知识来优化治疗。本研究旨在了解 Cahaya Medan 高中 12 年级学生对甜甜圈和甜口香糖是致龋食物的认知水平与龋齿经历之间的关系。调查方法通过问卷调查和检查牙齿收集数据。数据分析采用 Kruskal-Wallis 统计检验。这类研究是通过设计横断面进行分析调查。研究结果研究结果表明,样本中大多数人对食用甜甜圈和甜口香糖是致龋食物的认知水平足够高,DMFT 平均分为 0.63 ± 2.723。结论:可以得出结论,对甜甜圈和甜口香糖是致龋食物的认知水平越高,龋齿率越低。
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引用次数: 0
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Indonesian Journal of Rheumatology
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