Pub Date : 2024-02-01DOI: 10.1016/j.bioorg.2024.107192
Joy Debnath, Dhananjaya Keshamasetthy, Jacob Combs, Katherine Leon, D. Vullo, Abhijit Chatterjee, Robert McKenna, C. Supuran
{"title":"A comparative study of diaryl urea molecules with and without sulfonamide group on Carbonic anhydrase IX and XII inhibition and its consequence on breast cancer cells","authors":"Joy Debnath, Dhananjaya Keshamasetthy, Jacob Combs, Katherine Leon, D. Vullo, Abhijit Chatterjee, Robert McKenna, C. Supuran","doi":"10.1016/j.bioorg.2024.107192","DOIUrl":"https://doi.org/10.1016/j.bioorg.2024.107192","url":null,"abstract":"","PeriodicalId":503894,"journal":{"name":"Bioorganic Chemistry","volume":"26 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139883103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.bioorg.2024.107207
Elnaz Farzaneh, Mohammad Mohammadi, Pooya Raymand, Milad Noori, Sahand Golestani, Sara Ranjbar, Younes Ghasemi, M. Mohammadi‐Khanaposhtani, M. Asadi, Ensieh Nasli Esfahani, Hossein Rastegar, B. Larijani, Mohammad Mahdavi, Parham Taslimi
{"title":"Pyrano[2,3-b]chromone derivatives as novel dual inhibitors of α-glucosidase and α-amylase: Design, synthesis, biological evaluation, and in silico studies","authors":"Elnaz Farzaneh, Mohammad Mohammadi, Pooya Raymand, Milad Noori, Sahand Golestani, Sara Ranjbar, Younes Ghasemi, M. Mohammadi‐Khanaposhtani, M. Asadi, Ensieh Nasli Esfahani, Hossein Rastegar, B. Larijani, Mohammad Mahdavi, Parham Taslimi","doi":"10.1016/j.bioorg.2024.107207","DOIUrl":"https://doi.org/10.1016/j.bioorg.2024.107207","url":null,"abstract":"","PeriodicalId":503894,"journal":{"name":"Bioorganic Chemistry","volume":"95 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139832232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.bioorg.2024.107191
Grant D. Walby, Qi Gu, Hongfen Yang, Stephen F. Martin
{"title":"Structure-Affinity relationships of novel σ2R/TMEM97 ligands","authors":"Grant D. Walby, Qi Gu, Hongfen Yang, Stephen F. Martin","doi":"10.1016/j.bioorg.2024.107191","DOIUrl":"https://doi.org/10.1016/j.bioorg.2024.107191","url":null,"abstract":"","PeriodicalId":503894,"journal":{"name":"Bioorganic Chemistry","volume":"11 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139890550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Phenolics and terpenoids with good anti-inflammatory activity from the fruits of Amomum villosum and the anti-inflammatory mechanism of active diterpene","authors":"Yang Xu, De-juan Sun, Liangliang Xiong, Zhiqi Zhang, Yuxia Li, Kexin Liu, Hua Li, Lixia Chen","doi":"10.1016/j.bioorg.2024.107190","DOIUrl":"https://doi.org/10.1016/j.bioorg.2024.107190","url":null,"abstract":"","PeriodicalId":503894,"journal":{"name":"Bioorganic Chemistry","volume":"23 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139883610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genetic loss of Nrf1 and Nrf2 leads to distinct metabolism reprogramming of HepG2 cells by opposing regulation of the PI3K-AKT-mTOR signalling pathway","authors":"Rongzhen Deng, Yu-ping Zhu, Keli Liu, Qun Zhang, Shaofan Hu, Meng Wang, Yiguo Zhang","doi":"10.1016/j.bioorg.2024.107212","DOIUrl":"https://doi.org/10.1016/j.bioorg.2024.107212","url":null,"abstract":"","PeriodicalId":503894,"journal":{"name":"Bioorganic Chemistry","volume":"55 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139881953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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