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Correlation Between the Rh/ABO System and Infection Due to SARS Cov2 in Morocco* 摩洛哥 Rh/ABO 系统与 SARS Cov2 感染之间的相关性*
Pub Date : 2024-04-03 DOI: 10.36347/sajb.2024.v12i03.001
Sanaa Sabour Alaoui, Amine Bennouri, Hamide Farhane
The association between COVID-19, ABO blood group system and Rhesus needs to be explored in order to suggest a model of the mechanism linked to SARS CoV2 infection. A retrospective case-control association study was performed on the different regions of Morocco and carried out on a population of size n = 5039 including a total of 4268 COVID-19 patients and 771 control groups. The differences in the Rh/ABO blood group distribution between COVID-19 patients and the control group were analyzed. The relationship between ABO blood type, sexes, Rhesus and COVID-19 characteristics was analyzed. The analyzes of association between the blood group and the infection related to SARS CoV2 showed a statistically significant difference in the individuals of groups B, O, AB) respectively, but not blood group A. In addition, patients with the Rh+ phenotype are less vulnerable to infection therefore the latter are considered to have a protective effect, however the Rh- categories are more vulnerable to infection so they are risk factors. Blood type was related to some clinical characteristics of patients with COVID-19. The presence of the A and B antigens increase the risk of infection with SARS COV2. While the presence of anti A and anti B antibodies makes group O protector against infection. Patients with the Rh+ phenotype are less vulnerable to infection than Rh-therefore these are considered to have a protective effect which is the presence of the D antigen in red blood cells.
需要探讨 COVID-19、ABO 血型系统和恒河猴之间的关联,以便提出与 SARS CoV2 感染相关的机制模型。在摩洛哥不同地区进行了一项回顾性病例对照关联研究,研究对象为 n = 5039 人,其中包括 4268 名 COVID-19 患者和 771 名对照组。研究分析了 COVID-19 患者与对照组之间的 Rh/ABO 血型分布差异。分析了 ABO 血型、性别、恒河猴和 COVID-19 特征之间的关系。血型与 SARS CoV2 感染的相关性分析表明,B、O、AB 血型的个体之间的差异具有统计学意义,而 A 血型的个体之间的差异不具有统计学意义。此外,Rh+ 表型的患者不易受感染,因此后者被认为具有保护作用,但 Rh- 血型的患者更易受感染,因此他们是危险因素。血型与 COVID-19 患者的一些临床特征有关。A 型和 B 型抗原的存在会增加感染 COV2 严重急性呼吸系统综合症的风险。而抗 A 抗体和抗 B 抗体的存在则使 O 型血的人免受感染。Rh+ 表型的病人比 Rh 表型的病人更不容易受到感染,因此这些病人被认为具有保护作用,即红细胞中存在 D 抗原。
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引用次数: 0
An Examination of Tinnitus from Both Clinical and Epidemiological Perspectives: A Comprehensive Review Study 从临床和流行病学角度审视耳鸣:全面回顾研究
Pub Date : 2024-03-15 DOI: 10.36347/sajb.2024.v12i02.001
Deaa Mohammad Alsuleman, Alaa Mahmoud Salameh
Tinnitus refers to the subjective perception of sounds in the brain or ears, such as buzzing, clicking, or hissing, in the absence of any external auditory stimuli. It is a commonly encountered phenomenon among individuals worldwide. The primary aim of this study was to examine recent advancements in the literature concerning the frequency, origins, control, and therapy of the subject in question. The researchers utilized prominent research engines such as Google, Google Scholar, Science Direct, and others to gather publications about tinnitus. The findings indicated that tinnitus is widely prevalent on a global scale and can be ascribed to neurological, hereditary, and environmental reasons. The therapy and therapeutic options for this condition are diverse and depend on the underlying causes.
耳鸣是指在没有任何外部听觉刺激的情况下,大脑或耳朵主观感受到的声音,如嗡嗡声、咔嗒声或嘶嘶声。耳鸣是世界上常见的一种现象。本研究的主要目的是研究有关该主题的频率、起源、控制和治疗的最新文献进展。研究人员利用 Google、Google Scholar、Science Direct 等著名研究引擎收集有关耳鸣的出版物。研究结果表明,耳鸣在全球范围内广泛流行,可归因于神经、遗传和环境原因。耳鸣的治疗方法和治疗方案多种多样,取决于耳鸣的根本原因。
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引用次数: 0
Pediatric Pain Management: Exploring the Roles of Medical Staff and Families 儿科疼痛管理:探索医务人员和家属的角色
Pub Date : 2024-01-27 DOI: 10.36347/sajb.2024.v12i01.005
Omar Salah Refai, Omar Shahir Alrashdan
Pediatric pain is a significant medical problem that can affect children, their families, and healthcare professionals. It may arise from medical disorders such as surgical procedures, accidents, and other causes. The objective of this study was to examine the current literature on advancements in pediatric pain treatment and investigate the responsibilities of healthcare professionals and families in the management of pediatric pain. The researchers conducted a comprehensive search using prominent research engines such as Google Scholar, Science Direct, and PubMed. The researchers in this study conducted a comprehensive review of the relevant published literature and subsequently provided a concise summary of their findings. The findings of this study have substantiated that pediatric pain is a significant health issue that necessitates genuine and appropriate care. Nevertheless, the research has shown the emergence of many instruments that can be utilized to assess the degree of pain and effectively address it. Collectively, families play crucial roles in the administration of pediatric pain, which complements the responsibilities of medical personnel.
小儿疼痛是一个严重的医疗问题,会影响到儿童、他们的家人和医护人员。儿科疼痛可能由外科手术、意外事故等医疗失调或其他原因引起。本研究的目的是检查当前有关儿科疼痛治疗进展的文献,并调查医护人员和家庭在儿科疼痛管理中的责任。研究人员使用 Google Scholar、Science Direct 和 PubMed 等著名研究引擎进行了全面搜索。本研究的研究人员对已发表的相关文献进行了全面回顾,随后对研究结果进行了简明扼要的总结。本研究的结果证实,儿科疼痛是一个重要的健康问题,需要真正和适当的护理。然而,研究表明,许多工具可以用来评估疼痛程度并有效地解决疼痛问题。总之,家庭在处理儿科疼痛方面发挥着至关重要的作用,与医务人员的职责相辅相成。
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引用次数: 0
Exploring the Roles of Genetic Counseling in Pediatric Medicine 探索遗传咨询在儿科医学中的作用
Pub Date : 2024-01-27 DOI: 10.36347/sajb.2024.v12i01.004
Megbal Oudeh Alshurfat, Omar Salah Refai
In the field of pediatric treatment, genetic counseling is an essential instrument for lowering the prevalence of oncological disorders and uncommon diseases. The primary objective of this inquiry was to conduct a thorough literature analysis with the purpose of acquiring the most recent information on genetic counseling in the field of pediatrics. According to the findings of the investigation, the increased significance of genetic counseling can be attributed to the fact that technology improvements that can be implemented at each stage of the counseling process have contributed to the process. The identification of rare illnesses and oncology situations, such as retinoblastoma, can be accomplished with the astounding assistance of genetic counseling. Genetic counseling can be done to provide premarital information on genetic problems in order to reduce the likelihood of developing future illnesses such as thalassemia. This can be accomplished by utilizing genetic counseling. Genetic counseling is a vital practice that gives families and healthcare practitioners the ability to make well-informed decisions regarding an individual's health.
在儿科治疗领域,遗传咨询是降低肿瘤疾病和罕见疾病发病率的重要手段。本次调查的主要目的是进行全面的文献分析,以获取儿科领域遗传咨询的最新信息。根据调查结果,遗传咨询重要性的增加可归因于在咨询过程的每个阶段都可实施的技术改进促进了这一过程。在遗传咨询的大力协助下,罕见疾病和肿瘤(如视网膜母细胞瘤)的鉴定工作得以完成。遗传咨询可以提供有关遗传问题的婚前信息,以减少将来患上地中海贫血症等疾病的可能性。这可以通过利用遗传咨询来实现。遗传咨询是一项重要的实践活动,它使家庭和医疗保健从业人员能够就个人的健康做出明智的决定。
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引用次数: 0
Leveraging Artificial Intelligence and Machine Learning in Predicting and Managing Pandemics: Lessons Learnt and Future Implications in the Healthcare Sector 利用人工智能和机器学习预测和管理流行病:医疗保健领域的经验教训和未来影响
Pub Date : 2024-01-12 DOI: 10.36347/sajb.2024.v12i01.003
Steward Mudenda, Shafiq Mohamed
Artificial intelligence (AI) is a game changer in the healthcare, educational, and other sectors. The use of AI in the healthcare sector has shown that AI and machine learning should be promoted in the improvement of service provision, including in predicting and managing pandemics. This study assessed the roles of AI in predicting and managing pandemics with lessons learnt from the COVID-19 pandemic. A narrative review was conducted from December 2023 to January 2024 on the role of AI and machine learning in predicting and managing pandemics. A literature search was done using PubMed and Google Scholar. This study found that AI is useful in the healthcare sector and can be used to predict and manage pandemics. Additionally, AI can be used in disease modelling and improve public health service provision. There is a need to promote and strengthen the use of AI and machine learning in the healthcare sector.
人工智能(AI)将改变医疗保健、教育和其他领域的游戏规则。人工智能在医疗保健领域的应用表明,应促进人工智能和机器学习来改善服务的提供,包括预测和管理流行病。本研究评估了人工智能在预测和管理大流行病方面的作用,并从 COVID-19 大流行病中汲取了经验教训。2023 年 12 月至 2024 年 1 月期间,对人工智能和机器学习在预测和管理大流行病方面的作用进行了叙述性综述。我们使用 PubMed 和谷歌学术进行了文献检索。研究发现,人工智能在医疗保健领域非常有用,可用于预测和管理流行病。此外,人工智能还可用于疾病建模和改善公共卫生服务的提供。有必要促进和加强人工智能和机器学习在医疗保健领域的应用。
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引用次数: 0
Persistence of Urachus in A 7-Month-Old Male Patient with Surgical Resolution: Case Report 一名 7 个月大男性患者的尿道顽疾通过手术得以治愈:病例报告
Pub Date : 2024-01-09 DOI: 10.36347/sajb.2024.v12i01.001
Freddy Alexander Aldaz Vallejo, Wendy Vanessa Vaca Vega, Gabriela Michelle Tubay Vera, Tatiana del Rosario Pérez Landázuri, Andrea Elizabeth Sánchez Vega
Introduction: Patent urachus refers to a rare condition called urachus anomaly. These conditions are caused by the failure of the normal fetal tissue used to empty the fetal bladder to degenerate. Some of these urachal abnormalities are obvious at birth, while others are more subtle and are not diagnosed until adulthood or are discovered only incidentally after imaging for other reasons. Urachal anomalies in children with wet umbilical cord, persistent drainage, recurrent urinary tract infections, and recurrent umbilical cord infections require accurate and timely diagnosis to help relieve symptoms, prevent recurrent serious infections, and ensure timely treatment. Clinical case: The case of a 7-month-old male patient is presented. The mother reports umbilical granuloma of several months of evolution. He goes to a doctor where he suggests an ultrasound examination that rules out persistence of urachus. Mass in umbilical region persists, which is why she comes again. Evolution: By laparoscopic vision, umbilical hernia plus persistence of urachus is evident, findings such as the presence of indirect bilateral inguinal hernia are found. After surgery, the patient recovered satisfactorily. Conclusions: Diagnosis of urachal anomalies can be elusive, but continued drainage of the umbilical cord is a concern in the case of urachal anomalies. Although this condition is usually an isolated finding, the possibility of posterior urethral valves in infants with a patent urachus should not be ruled out.
导言尿道闭锁是一种罕见的疾病,称为尿道异常。这些疾病是由于用于排空胎儿膀胱的正常胎儿组织未能退化造成的。有些泌尿道异常在出生时就很明显,而有些则比较隐蔽,直到成年后才被诊断出来,或者由于其他原因在进行造影检查后才偶然发现。脐带潮湿、持续引流、反复尿路感染和反复脐带感染患儿的泌尿道异常需要准确及时的诊断,以帮助缓解症状、预防反复严重感染并确保及时治疗。临床病例:本病例为一名 7 个月大的男性患者。他的母亲报告说,脐肉芽肿已经发展了几个月。他去看医生,医生建议进行超声波检查,排除了尿道持续存在的可能。但脐部肿块仍然存在,这就是她再次就诊的原因。演变:通过腹腔镜检查,脐疝和尿道持续存在是显而易见的,还发现了间接性双侧腹股沟疝等结果。手术后,患者恢复良好。结论尿道畸形的诊断可能难以捉摸,但脐带持续引流是尿道畸形病例需要关注的问题。虽然这种情况通常只是个别现象,但不应排除尿道通畅的婴儿出现后尿道瓣膜的可能性。
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引用次数: 0
In Vitro Study of the Antiparasitic Activity of Vitellaria paradoxa Gaertn (Sapotaceae) on the Parasite Onchocerca ochengi Vitellaria paradoxa Gaertn(山榄科植物)对寄生虫 Onchocerca ochengi 的体外抗寄生活性研究
Pub Date : 2024-01-09 DOI: 10.36347/sajb.2024.v12i01.002
Martinien Atakewang Djetoloum, Nadlaou Bessimbaye, Mbaïnguinam Mbailao
Onchocerciasis is a parasitic disease that affects millions of animals and people around the world. A recipe based on Vitellaria paradoxa is used in traditional medicine against this disease in Chad. The objective of this study was to evaluate the antiparasitic activities of extracts from the roots, fruits, leaves and bark of Vitellaria paradoxa on the parasitic nematode Onchocerca ochengi, a model similar to Onchocerca volvulus used in the research of control drugs. against onchocerciasis. The identification of parasites and the hydroethanolic extracts of the different planar organs were carried out at the Laboratory of Research, Diagnostics and Scientific Expertise (LaboReDES) of the Faculty of Human Sciences, University of N'Djamena using the methods of Ndjonka et al., 2012. The extracts of this plant were tested at different concentrations (0.1; 0.2; 0.3; 0.4 mg/mL) in the RPMI-1640 culture medium. The antiparasitic activity was noted according to the mortality rate after 72 hours of incubation of Onchocerca ochengi at 37°C. The LC50 values were then graphically determined at the end of this incubation. They were 0.05 mg/mL for the roots; 0.06 mg/mL for fruits; 0.05 mg/mL for the leaves and 0.06 mg/mL for the bark. These results confirm the effectiveness of Vitellaria paradoxa used in traditional medicine to treat parasitosis. This plant also has the same effects as ivermectin. The V. paradoxa root test on microfilariae shows an LC50 value of 0.05 mg/mL in 24 hours of incubation. This study showed that the hydroethanolic extracts of the bark of Vitellaria paradoxa had antiparasitic activities, allowing the development of a new molecule active against these parasitic infections and also the extracts of this plant could be used as alternatives to treat infections in case of parasite resistance to ivermectin.
盘尾丝虫病是一种寄生虫病,影响着全世界数百万动物和人类。在乍得,一种基于藤黄的配方被用于防治这种疾病的传统医药中。这项研究的目的是评估从藤黄属植物的根、果实、叶子和树皮中提取的提取物对寄生线虫Onchocerca ochengi的抗寄生活性,Onchocerca ochengi是一种类似于盘尾丝虫的模型,用于研究防治盘尾丝虫病的药物。恩贾梅纳大学人文科学学院研究、诊断和科学专家实验室(LaboReDES)采用 Ndjonka 等人 2012 年的方法对寄生虫和不同平面器官的水乙醇提取物进行了鉴定。在 RPMI-1640 培养基中以不同浓度(0.1;0.2;0.3;0.4 mg/mL)对这种植物的提取物进行了测试。抗寄生虫活性是根据在 37°C 下孵育 72 小时后尾孢子虫的死亡率来确定的。然后在培养结束时以图形方式确定 LC50 值。根部的半致死浓度为 0.05 毫克/毫升;果实的半致死浓度为 0.06 毫克/毫升;叶片的半致死浓度为 0.05 毫克/毫升;树皮的半致死浓度为 0.06 毫克/毫升。这些结果证实了传统医学中使用的藤黄对治疗寄生虫病的有效性。这种植物还具有与伊维菌素相同的功效。对微丝蚴的根部测试显示,在 24 小时的培养过程中,半数致死浓度为 0.05 毫克/毫升。这项研究表明,藤黄属植物树皮的水乙醇提取物具有抗寄生虫活性,因此可以开发出对这些寄生虫感染具有活性的新分子,而且在寄生虫对伊维菌素产生抗药性的情况下,这种植物的提取物还可用作治疗感染的替代品。
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Scholars Academic Journal of Biosciences
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