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International Endometrial Tumor Analysis (IETA) descriptors in the diagnosis of chronic endometritis 国际子宫内膜肿瘤分析(IETA)描述符在慢性子宫内膜炎诊断中的应用
Pub Date : 2024-02-13 DOI: 10.24835/1607-0771-2023-3-50-66
I. A. Ozerskaya, G. Kazaryan, E. V. Minashkona, A. I. Gus
Objective: to compare the terms, definitions and measurement methods developed by the IETA group with the ultrasound criteria of chronic endometritis (CE) used in Russia.Material and methods. A retrospective cohort study of 158 reproductive age women with clinical and laboratory diagnosis of CE was carried out. Sonographic examination was performed in the early or middle proliferative phase (cycle day 4–10 days) with the use of Affiniti70 ultrasound system (Philips, the Netherlands) with a multifrequency 3D endocavitary probe. Uterine corpus volume, endometrial thickness and volume were measured, followed by percentage endometrial/uterine volume ratio calculation, the so-called adjusted endometrial volume. Qualitative analysis of grayscale imaging included assessment of endometrial structure and echogenicity; closure or separation of the endometrial layers; contour of endometrial midline; the presence of acoustic artifacts, such as reverberation in the presence of gas or liquid in the uterine cavity, described by a number of authors. Relevant IETA descriptions were searched when assessing all qualitative CE features. In parallel, a qualitative score analysis proposed by the IETA group was carried out.Timely preoperative diagnosis of endometrioic cyst (endometrioma), as well as deep endometriosis remains relevant. The aim of the study was to assess the diagnostic value of ultrasound in patients with endometriomas and assess the combination of them with other foci of external genital endometriosis. The study based on retrospective analysis of a date of 95 patients with ultrasound signs of ovarian endometriomas, who underwent examination in MedicoProfi LLC – Borisov Medical and Diagnostic Clinic (Krasnoyarsk) during the period from January 2019 to October 2023. All of patients underwent surgery , followed by morphological evaluation. In the vast majority of cases, it was possible to detect a combination of endometriomas with one or more foci of deep endometriosis. Superficial peritoneal endometriosis and adhesions were found on surgery in all cases when endometriomas appeared isolated on ultrasound. The results of the study showed: endometriomas combined with deep endometriosis in 96.8% of cases. Thus, ultrasound detection of endometrioma is a very reliable sign of deep endometriosis presence. The “kissing ovaries” symptom in bilateral endometriomas can be considered as an absolutely reliable sign of the uterosacral ligaments endometriosis with specificity of 100% and positive predictive value of 100%. The presence of the “kissing ovaries” sign should be depicted in the conclusion of the ultrasound protocol, since it highly suggestive to obliteration of the pouch of Douglas and involvement of adjacent organs (fallopian tubes, intestines, ureters, etc.) in the endometrioid infiltrates, which is extremely important for the surgery planning, as well as in patients with infertility. There is an obvious need to introduce the extended pelvic ultrasound pr
目的:将 IETA 小组制定的术语、定义和测量方法与俄罗斯使用的慢性子宫内膜炎(CE)超声标准进行比较。对 158 名临床和实验室诊断为 CE 的育龄妇女进行了回顾性队列研究。超声检查在增殖期早期或中期(周期第 4-10 天)进行,使用 Affiniti70 超声系统(荷兰飞利浦公司)和多频三维腔内探头。测量子宫体体积、子宫内膜厚度和体积,然后计算子宫内膜/子宫体积百分比,即所谓的调整后子宫内膜体积。灰阶成像的定性分析包括评估子宫内膜的结构和回声;子宫内膜层的闭合或分离;子宫内膜中线的轮廓;是否存在声学伪影,如一些作者描述的宫腔内存在气体或液体时的混响。在评估 CE 的所有定性特征时,搜索了相关的 IETA 描述。与此同时,还对 IETA 小组提出的定性评分进行了分析。术前及时诊断子宫内膜异位囊肿(子宫内膜瘤)和深部子宫内膜异位症仍具有重要意义。该研究旨在评估超声对子宫内膜异位症患者的诊断价值,并评估子宫内膜异位症与其他外生殖器子宫内膜异位症病灶的结合情况。该研究基于对2019年1月至2023年10月期间在MedicoProfi LLC - Borisov医疗诊断诊所(克拉斯诺亚尔斯克)接受检查的95名卵巢子宫内膜异位症超声波征象患者的回顾性分析。所有患者都接受了手术,随后进行了形态学评估。在绝大多数病例中,都能发现子宫内膜异位症与一个或多个深部子宫内膜异位症病灶的结合。在所有超声显示为孤立子宫内膜异位症的病例中,手术均发现了腹膜浅层子宫内膜异位症和粘连。研究结果显示:96.8%的病例中子宫内膜异位症合并有深部子宫内膜异位症。因此,子宫内膜瘤的超声检测是深部子宫内膜异位症存在的一个非常可靠的标志。双侧子宫内膜异位症中的 "亲吻卵巢 "症状可视为子宫骶骨韧带子宫内膜异位症的绝对可靠征兆,特异性为 100%,阳性预测值为 100%。在超声检查方案的结论中应描述 "亲吻卵巢 "征象的存在,因为它高度提示子宫内膜异位症浸润会导致道格拉斯袋阻塞和邻近器官(输卵管、肠道、输尿管等)受累,这对手术计划和不孕症患者都极为重要。对于疑似子宫内膜异位症患者的诊断算法,显然有必要引入扩展盆腔超声方案,这将更准确地描述疾病的扩展情况。对 CE 中子宫内膜描述的对比分析表明,子宫内膜和子宫内病变厚度的测量技术相似,均由 IETA 小组提出,并在我国使用。IETA 对超声定性结果的描述大多可用于 CE 诊断。然而,在 IETA 的描述中,并没有一些重要的超声特征可用于鉴别炎症,如明显、部分或完全增厚的中线,以及子宫内膜或宫腔内的气体灶。如果研究人员使用相似的描述符,术语标准化有助于对结果进行比较,并进行多中心研究和荟萃分析,以诊断慢性子宫内膜炎。
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引用次数: 0
Ultrasound image of ovarian endometrioma as an indicator of external genital endometriosis 作为外生殖器子宫内膜异位症指标的卵巢子宫内膜瘤超声图像
Pub Date : 2024-02-13 DOI: 10.24835/1607-0771-2023-3-37-49
E. A. Borisova, M. N. Bulanov, T. A. Makarenko
Timely preoperative diagnosis of endometrioic cyst (endometrioma), as well as deep endometriosis remains relevant. The aim of the study was to assess the diagnostic value of ultrasound in patients with endometriomas and assess the combination of them with other foci of external genital endometriosis. The study based on retrospective analysis of a date of 95 patients with ultrasound signs of ovarian endometriomas, who underwent examination in MedicoProfi LLC – Borisov Medical and Diagnostic Clinic (Krasnoyarsk) during the period from January 2019 to October 2023. All of patients underwent surgery , followed by morphological evaluation. In the vast majority of cases, it was possible to detect a combination of endometriomas with one or more foci of deep endometriosis. Superficial peritoneal endometriosis and adhesions were found on surgery in all cases when endometriomas appeared isolated on ultrasound. The results of the study showed: endometriomas combined with deep endometriosis in 96.8% of cases. Thus, ultrasound detection of endometrioma is a very reliable sign of deep endometriosis presence. The “kissing ovaries” symptom in bilateral endometriomas can be considered as an absolutely reliable sign of the uterosacral ligaments endometriosis with specificity of 100% and positive predictive value of 100%. The presence of the “kissing ovaries” sign should be depicted in the conclusion of the ultrasound protocol, since it highly suggestive to obliteration of the pouch of Douglas and involvement of adjacent organs (fallopian tubes, intestines, ureters, etc.) in the endometrioid infiltrates, which is extremely important for the surgery planning, as well as in patients with infertility. There is an obvious need to introduce the extended pelvic ultrasound protocol to the diagnostic algorithm for patients with suspected endometriosis, which will more accurately describe the disease extension.
及时进行子宫内膜异位囊肿(子宫内膜瘤)和深部子宫内膜异位症的术前诊断仍具有重要意义。该研究旨在评估子宫内膜异位症患者的超声诊断价值,并评估其与外生殖器子宫内膜异位症其他病灶的结合情况。该研究基于对2019年1月至2023年10月期间在MedicoProfi LLC - Borisov医疗诊断诊所(克拉斯诺亚尔斯克)接受检查的95名卵巢子宫内膜异位症超声波征象患者的回顾性分析。所有患者都接受了手术,随后进行了形态学评估。在绝大多数病例中,都能发现子宫内膜异位症与一个或多个深部子宫内膜异位症病灶的结合。在所有超声显示为孤立子宫内膜异位症的病例中,手术均发现了浅表腹膜子宫内膜异位症和粘连。研究结果显示:96.8%的病例中子宫内膜异位症合并有深部子宫内膜异位症。因此,子宫内膜瘤的超声检测是深部子宫内膜异位症存在的一个非常可靠的标志。双侧子宫内膜异位症中的 "亲吻卵巢 "症状可视为子宫骶骨韧带子宫内膜异位症的绝对可靠征兆,特异性为 100%,阳性预测值为 100%。在超声检查方案的结论中应描述 "亲吻卵巢 "征象的存在,因为它高度提示子宫内膜异位症浸润会导致道格拉斯袋阻塞和邻近器官(输卵管、肠道、输尿管等)受累,这对手术计划和不孕症患者都极为重要。显然,有必要在疑似子宫内膜异位症患者的诊断算法中引入扩展盆腔超声方案,这将更准确地描述疾病的扩展情况。
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引用次数: 0
Ultrasound signs of fetal chromosomal abnormalities at 11–14 weeks of pregnancy and its value in the era of modern genetic testing 妊娠 11-14 周胎儿染色体异常的超声波征象及其在现代基因检测时代的价值
Pub Date : 2024-02-13 DOI: 10.24835/1607-0771-2023-3-67-95
M. M. Bulanova, D. S. Smirnova, O. Panina
A steady increase in average maternity age at the time of first childbirth lead to a higher risk of fetal chromosomal abnormalities. The Order No. 1130n of the Ministry of Health of the Russian Federation establish the screening protocol at 11–14 weeks of gestation with assessing the followed criteria of fetal chromosomal pathology: the nuchal translucency thickness, nasal bone measurement, ductus venosus pulsatility index, tricuspid regurgitation, and heart rate. The value of non-invasive prenatal testing (NIPT) in the early prenatal diagnosis of the most common chromosomal abnormalities, as the trisomies 21, 18, 13, and monosomy X is also increasing. Additionally, numerous other fetal karyotype abnormalities can also be suspected at 11–14 weeks of gestation by revealing a number of other ultrasound signs. The article presents the literature review on additional ultrasound signs of various, both more and less common, chromosomal abnormalities. Pathological signs, abnormalities of fetal anatomy and extrafetal structures in the first trimester, which could be used as additional ultrasound signs of chromosomal pathology of various organs and systems (central nervous system and head, heart and blood vessels, urinary system, abdominal organs, fetal skeleton, as well as the placenta, umbilical cord, amniotic membranes) are described in the article. Despite the use of NIPT, including its extended panels, there remains a need to use ultrasound to detect the signs of rarer, but no less significant chromosomal pathologies, such as triploidies, mosaic trisomies, rare autosomal trisomies, duplications, and deletions.
初产妇的平均生育年龄不断增加,导致胎儿染色体异常的风险增加。俄罗斯联邦卫生部第 1130n 号令规定了妊娠 11-14 周的筛查方案,评估胎儿染色体病变的标准如下:颈项透明层厚度、鼻骨测量、静脉导管搏动指数、三尖瓣反流和心率。无创产前检测(NIPT)在早期产前诊断最常见染色体异常(如 21、18、13 三体和 X 单体)方面的价值也在增加。此外,在妊娠 11-14 周时,许多其他胎儿染色体核型异常也可通过显示其他一些超声征象而被怀疑。本文介绍了各种较常见或不常见染色体异常的其他超声征象的文献综述。文章介绍了妊娠头三个月胎儿解剖结构和胎儿外结构的病理征象、异常,这些可作为各器官和系统(中枢神经系统和头部、心脏和血管、泌尿系统、腹部器官、胎儿骨骼以及胎盘、脐带、羊膜)染色体病变的附加超声征象。尽管已经使用了 NIPT(包括其扩展面板),但仍有必要使用超声检测较罕见但同样重要的染色体病变,如三倍体、镶嵌三体、罕见常染色体三体、重复和缺失。
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引用次数: 0
Differential ultrasound diagnosis of benign and malignant ovarian tumors: diagnostic models, algorithms, stratification systems, consensuses (1990–2023). 良性和恶性卵巢肿瘤的超声鉴别诊断:诊断模型、算法、分层系统、共识(1990-2023 年)。
Pub Date : 2023-12-22 DOI: 10.24835/1607-0771-2023-2-34-61
M. N. Bulanov, M. A. Chekalova, M. V. Mazurkevich, N. N. Vetsheva
The review presents the most common diagnostic models, algorithms and stratification systems developed for the purpose of optimal differential diagnosis of benign and malignant ovarian tumors from 1990 to the present. Four variants of the RMI 1–4 malignancy risk index with their comparative characteristics are described. A proprietary comprehensive ultrasound scoring scale for ovarian tumors is described. Algorithms for the integrated use of echography and tumor markers (CA-125, HE4, ROMA), including the Risk Ovarian Cancer computer system, are presented. All existing IOTA diagnostic models are described: Simple IOTA rules, Simple IOTA rules with quantitative calculation of the risk of malignancy, Logistic regression analysis IOTA LR1 & LR2, Easy IOTA descriptors, IOTA ADNEX. The main algorithms for the integrated use of IOTA models are presented. The principles of using the diagnostic stratification systems GI-RADS and O-RADS are outlined. Clinical examples of the use of diagnostic models are given. The review concludes by presenting the ESGO/ISUOG/IOTA/ESGE consensus on the preoperative diagnosis of ovarian tumors.
本综述介绍了 1990 年至今为优化卵巢良恶性肿瘤鉴别诊断而开发的最常见诊断模型、算法和分层系统。介绍了 RMI 1-4 恶性风险指数的四种变体及其比较特征。介绍了专有的卵巢肿瘤超声综合评分表。介绍了综合使用超声波和肿瘤标志物(CA-125、HE4、ROMA)的算法,包括卵巢癌风险计算机系统。介绍了所有现有的 IOTA 诊断模型:简单 IOTA 规则、定量计算恶性肿瘤风险的简单 IOTA 规则、逻辑回归分析 IOTA LR1 和 LR2、简易 IOTA 描述符、IOTA ADNEX。介绍了综合使用 IOTA 模型的主要算法。概述了 GI-RADS 和 O-RADS 诊断分层系统的使用原则。给出了使用诊断模型的临床实例。综述最后介绍了 ESGO/ISUOG/IOTA/ESGE 关于卵巢肿瘤术前诊断的共识。
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引用次数: 0
High-resolution ultrasound in diagnosing complications after facial contouring injections. A clinical case. 高分辨率超声波诊断面部轮廓注射后的并发症。临床案例。
Pub Date : 2023-12-22 DOI: 10.24835/1607-0771-2023-2-80-87
E. G. Privalova, E. I. Karpova, M. V. Kozyreva, V. V. Kapustin, Y. Chebotareva, O. I. Danishchouk
The development of new techniques of procedure and line extensions of products for facial contouring injections leads to an increase in the incidence of facial soft tissue complications and adverse reactions. The article presents a clinical case of complications after previous facial contouring injections with hyaluronic acid-based fillers. In high-resolution ultrasound the signs of inflammatory changes in the facial soft tissues were found, which affected the further treatment strategy.
随着面部轮廓注射新技术的发展和产品线的延伸,面部软组织并发症和不良反应的发生率也随之增加。本文介绍了一例使用透明质酸类填充剂进行面部轮廓注射后出现并发症的临床病例。在高分辨率超声波检查中发现面部软组织有炎症变化的迹象,这影响了进一步的治疗策略。
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引用次数: 0
Predictive value of left ventricular global function index in patients with aortic stenosis 主动脉瓣狭窄患者左心室整体功能指数的预测价值
Pub Date : 2023-12-22 DOI: 10.24835/1607-0771-2023-2-9-22
A. Kapustina, L. Minushkina, M. Alekhin, T. A. Tipteva, V. I. Safaryan, O. S. Chumakova, D. Zateyshchikov
A number of factors has an impact on the survival prognosis in aortic stenosis patients. One of these factors is a left ventricular (LV) systolic function. Left ventricular global function index (LVGFI) takes into account the components of LV remodeling: LV volume, LV stroke volume, and LV myocardial volume.Objective: to evaluate the prognostic value of LVGFI in patients with various aortic stenosis severity using echocardiography.Material and methods. The study based on the data of previous prospective observational study from 2010–2016, followed by retrospective calculation and analysis of the LVGFI obtained by echocardiography. A total of 377 patients were included to the study, the average age was 79 (75–84) years; 128 (34%) of them were male; 70 patients (19%) had mild aortic stenosis, 116 patients (31%) moderate aortic stenosis, and 191 patients (50%) severe aortic stenosis. LVGFI was calculated as the percentage ratio of LV stroke volume to LV global volume, where LV global volume was defined as the sum of the LV mean cavity volume [(LV end-diastolic volume + LV end-systolic volume)/2] and the myocardium volume. LV myocardial volume was calculated as the ratio of LV myocardial mass to LV density (defined as 1.05 g/mL). The average follow-up period at the moment of analysis was 602.7 ± 48.72 days. All cases of death during the period of follow up were captured.Results. The significant differences of LVGFI obtained between surviving and deceased patients (15.39% (11.35–20.95%) and 20.12% (15.16–25.98%), respectively, p < 0.001). Values of LVGFI < 18% significantly associated with the risk of death from all causes during two years of follow-up in both mild aortic stenosis and moderate and severe aortic stenosis.Conclusion. Thus, in patients with aortic stenosis in the group of fatal outcomes the values of the LVGFI were significantly lower than in the group of surviving patients. LVGFI values of less than 18% associated with the risk of death from all causes in any grade of aortic stenosis. LVGFI can be used for mortality risk stratification in patients with aortic stenosis.
有许多因素会影响主动脉瓣狭窄患者的生存预后。其中一个因素是左心室收缩功能。左心室整体功能指数(LVGFI)考虑了左心室重塑的各个组成部分:目的:使用超声心动图评估 LVGFI 在不同主动脉瓣狭窄严重程度患者中的预后价值。该研究基于 2010-2016 年的前瞻性观察研究数据,然后对超声心动图获得的 LVGFI 进行回顾性计算和分析。研究共纳入377例患者,平均年龄为79(75-84)岁;其中128例(34%)为男性;70例(19%)为轻度主动脉瓣狭窄,116例(31%)为中度主动脉瓣狭窄,191例(50%)为重度主动脉瓣狭窄。LVGFI 以 LV 搏出量与 LV 总容积的百分比率计算,其中 LV 总容积定义为 LV 平均腔容积 [(LV 舒张末期容积 + LV 收缩末期容积)/2] 与心肌容积之和。左心室心肌容积按左心室心肌质量与左心室密度(定义为 1.05 克/毫升)之比计算。分析时的平均随访时间为 602.7 ± 48.72 天。随访期间的所有死亡病例均被记录在案。存活患者和死亡患者的 LVGFI 存在明显差异(分别为 15.39% (11.35-20.95%) 和 20.12% (15.16-25.98%),P < 0.001)。LVGFI值小于18%与轻度主动脉瓣狭窄、中度和重度主动脉瓣狭窄患者在两年随访期间死于各种原因的风险显著相关。因此,在主动脉瓣狭窄致死组患者中,LVGFI 值明显低于存活组患者。LVGFI值低于18%与任何等级的主动脉瓣狭窄患者因各种原因死亡的风险有关。LVGFI 可用于主动脉瓣狭窄患者的死亡风险分层。
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引用次数: 0
The significance of two-dimensional speckle-tracking echocardiography of the left atrium in patients with atrial fibrillation. 心房颤动患者左心房二维斑点追踪超声心动图的意义。
Pub Date : 2023-12-22 DOI: 10.24835/1607-0771-2023-2-23-33
M. G. Matveeva, M. Alekhin
This article is a review of the literature devoted to the analysis of promising directions for the use of left atrial strain evaluated using speckle-tracking echocardiography to predict atrial fibrillation (AF). Left atrial strain parameters in various phases of the cardiac cycle are independent predictors of AF both in patients with heart failure and in the general population. The addition of left atrial strain parameters to the traditional echocardiographic parameters will make it possible to effectively select patients with AF both for catheter ablation and to identify patients with a high risk of AF recurrence after catheter ablation.
本文是一篇文献综述,专门分析了利用斑点追踪超声心动图评估的左心房应变预测心房颤动(房颤)的前景方向。心动周期不同阶段的左心房应变参数是心衰患者和普通人群房颤的独立预测指标。在传统超声心动图参数的基础上增加左心房应变参数,可以有效地选择房颤患者进行导管消融,并识别导管消融后房颤复发风险高的患者。
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引用次数: 0
Musculoskeletal ultrasound in gout. 痛风的肌肉骨骼超声检查
Pub Date : 2023-12-22 DOI: 10.24835/1607-0771-2023-2-62-79
E. V. Polukhina
The article presents a pictorial literature review on musculoskeletal ultrasound in gout, which is the most common cause of inflammatory arthropathy in adults. Nowadays, among imaging modalities, ultrasound provides the best capabilities for gout diagnosing and monitoring by revealing of monosodium urate deposits in various joint structures, assessing the presence and severity of synovial inflammation, including for dynamical evaluation on urate-lowering therapy. The main ultrasound features of gout (double contour sign, tophi, aggregates and erosions) are described according to the current clinical guidelines. Knowing of these features provides the correct interpretation of ultrasound findings for timely diagnosis and differential diagnosis of gouty arthropathy, and dynamical assessment on therapy.
痛风是成人炎症性关节病最常见的病因,本文以图文并茂的方式对痛风的肌肉骨骼超声进行了综述。目前,在各种影像学检查方法中,超声检查是诊断和监测痛风的最佳方法,它能显示各种关节结构中的单钠尿酸盐沉积,评估滑膜炎症的存在和严重程度,包括对降尿治疗进行动态评估。根据目前的临床指南,对痛风的主要超声特征(双轮廓征、丘疹、聚集和侵蚀)进行了描述。了解了这些特征,就能正确解读超声检查结果,及时诊断和鉴别诊断痛风性关节病,并对治疗进行动态评估。
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引用次数: 0
期刊
Ultrasound &amp; Functional Diagnostics
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