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Lifetime attributable risk of cancer incidence in whole-body 18F-Fluorodeoxyglucose PET/CT scans via 3rd order polynomial approach 通过三阶多项式方法计算全身 18F 氟脱氧葡萄糖 PET/CT 扫描中癌症发病率的终生归因风险
Pub Date : 2024-08-09 DOI: 10.1051/radiopro/2024034
H. Murat, M. Kechik, M. T. Chew, I. Kamal, M. A. Said, M. J. Ibahim, M. K. A. Karim
The advent of PET/CT examinations has revolutionized cancer treatment, offering greater precision in diagnosis. Nonetheless, the ionizing radiation exposure during the examination could cause a cancer risk. Hence, this study aimed to evaluate the radiation dose and radiation-induced risk associated of whole-body PET/CT scan that includes the 18F-FDG tracers. For this retrospective study, 40 participants were studied, with an even number of males and females. The average age and weight of the participants were 53.77 ± 15.78 years and 66.59 ± 16.94 kg respectively, and they were administered 424.64 ± 121.19 MBq of 18F-FDG before the PET/CT commenced. The IDAC-Dose 2.1 program was employed to calculate the absorbed dose and effective dose in organs such as the bladder, brain, lung, kidneys, colon, red bone marrow (RBM), stomach, liver, and thyroid. The potential risks of cancer were evaluated using the lifetime attributable risk (LAR) via a 3rd order polynomial approach based on the information provided in the Biological Effects of Ionizing Radiation (BEIR) VII report. The effective dose was 20.1 ± 7.9 mSv, and the ratio of E to administered activity is 1.612 × 10-2 mSv/MBq, which is in line with the ICRP standard. The study found that the average incidence of cancer among men and women was 7 and 8 cases per 100,000 examinations, respectively, with effective dose between 3.2 mSv to 27.3 mSv. In summary, the risk of cancer associated with current whole-body 18F-FDG PET/CT examinations is low, but it is essential to mitigate radiation exposure during these examinations and utilize suitable techniques to prevent stochastic effects from low-dose radiation exposure.
PET/CT 检查的出现彻底改变了癌症治疗,使诊断更加精确。然而,检查过程中的电离辐射照射可能会导致癌症风险。因此,本研究旨在评估全身 PET/CT 扫描(包括 18F-FDG 示踪剂)的辐射剂量和辐射诱发风险。在这项回顾性研究中,有 40 名参与者接受了研究,其中男性和女性人数相等。参与者的平均年龄和体重分别为(53.77 ± 15.78)岁和(66.59 ± 16.94)公斤,他们在 PET/CT 扫描开始前接受了 424.64 ± 121.19 MBq 的 18F-FDG 治疗。采用 IDAC-Dose 2.1 程序计算了膀胱、脑、肺、肾、结肠、红骨髓(RBM)、胃、肝和甲状腺等器官的吸收剂量和有效剂量。根据电离辐射的生物效应(BEIR)VII 报告中提供的信息,通过三阶多项式方法,使用终生可归因风险(LAR)对潜在的癌症风险进行了评估。有效剂量为 20.1 ± 7.9 mSv,E 与施用活度的比率为 1.612 × 10-2 mSv/MBq,符合国际放射防护委员会的标准。研究发现,在有效剂量介于 3.2 mSv 至 27.3 mSv 之间的情况下,男性和女性的癌症平均发病率分别为每 10 万例检查中有 7 例和 8 例。总之,目前与全身 18F-FDG PET/CT 检查相关的癌症风险很低,但必须在这些检查过程中减少辐照,并利用适当的技术防止低剂量辐照的随机效应。
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引用次数: 0
Advancing Patient Safety in Interventional Radiology: Effective Dose Evaluation and LDRL 促进介入放射学中的患者安全:有效剂量评估和 LDRL
Pub Date : 2024-08-08 DOI: 10.1051/radiopro/2024031
Alvarez M, Guassu Rac, Rosa Aa, Sousa Rr, DP Pina
This study highlights the significance of radioprotection in interventional radiology, focusing on the assessment of Effective Dose values to which patients are exposed. To facilitate this, we developed a semi-automatic software employing Optical Character Recognition technology. This software analysed 1125 interventional procedures conducted between January 2021 and September 2023 at a large Brazilian hospital. The database includes the type of procedure, Air Kerma value, Kerma-Area Product, number of cineangiography images, and exposure duration, all realized on an Artis Zee® (Siemens Healthineers, Germany) C-arm. We established Local Diagnostic Reference Levels (LDRLs) and calculated Effective Dose values using the PCXMC 2.0 Monte Carlo simulation software. These calculations were based on data from the hospital and LDRLs determined in subsequent studies. The findings reveal that both the LDRLs and the calculated Effective Dose generally fall below the values reported in existing literature. This underscores the efficacy of our methodology in enhancing radioprotection and dose monitoring within the studied hemodynamics sector.
这项研究强调了放射防护在介入放射学中的重要性,重点是评估患者所暴露的有效剂量值。为此,我们开发了一款采用光学字符识别技术的半自动软件。该软件分析了巴西一家大型医院在 2021 年 1 月至 2023 年 9 月期间进行的 1125 例介入手术。数据库包括手术类型、Air Kerma值、Kerma-Area乘积、电影血管造影图像数量和曝光持续时间,所有这些都是在Artis Zee®(德国西门子医疗集团)C型臂上实现的。我们使用 PCXMC 2.0 蒙特卡洛模拟软件确定了局部诊断参考水平 (LDRL) 并计算了有效剂量值。这些计算基于医院的数据和后续研究确定的 LDRL。研究结果表明,LDRL 和计算出的有效剂量一般都低于现有文献报道的数值。这凸显了我们的方法在所研究的血液动力学领域内加强辐射防护和剂量监测的有效性。
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引用次数: 0
Thermoluminescence dosimetry in small animal digital radiography, the dose to animals, and their adopters 小动物数字放射摄影中的热释光剂量测定、动物及其领养者所受的剂量
Pub Date : 2024-08-08 DOI: 10.1051/radiopro/2024035
E. Saeedian, M. Shakerian, A. ZarifSanayei, Z. Rakeb, F. N. Alizadeh, S. Sina
In veterinary radiology, The dose to radiation workers, animals, and the public should be reduced as low as reasonably achievable. Immobilization of the pets is necessary for obtaining images with acceptable image quality. The adopters are usually asked to immobilize their pets during the imaging. Therefore the dose equivalent values received by the animal adopters are also important. This study aims to assess the dose to the hands and whole body of the adopter and the entrance skin dose (ESD) to the animals undergoing radiographic imaging using LiF: Mg, Ti (TLD 100) for one month of work in a veterinary hospital in Shiraz. The results showed that the dose received by the animals varied from 0.20 mSv to 0.53 mSv. The average dose equivalent values to hands, Hp(0.07), and body, Hp(10) of adopters are 0.35, and 0.14 mSv Respectively.
在兽医放射学中,辐射工作人员、动物和公众所受的剂量应尽可能减少。要获得图像质量可接受的图像,必须固定宠物。通常会要求领养者在成像过程中固定宠物。因此,动物领养者收到的剂量当量值也很重要。本研究旨在评估在设拉子一家兽医院工作一个月期间,使用 LiF:Mg,Ti(TLD 100)进行放射成像时,领养者双手和全身所受的剂量以及动物皮肤入口剂量(ESD)。结果显示,动物接受的剂量从 0.20 mSv 到 0.53 mSv 不等。领养者手部(Hp(0.07))和身体(Hp(10))的平均剂量当量值分别为 0.35 和 0.14 mSv。
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引用次数: 0
Protection During Radiotherapy: Selenium 放疗期间的保护:硒
Pub Date : 2024-08-08 DOI: 10.1051/radiopro/2024032
JY. Yan, D. Li
The multifaceted applications of nuclear technology, especially in cancer treatment through radiotherapy, bring considerable benefits to our daily lives but also necessitate the imperative for effective strategies to effectively mitigate radiation-induced issues. While strict compliance with usage specifications is essential, ensuring proper protection against radiation-induced damages is crucial. Selenium, in its various forms including selenomethionine, Ebselen, and sodium selenite, emerges as a promising radioprotective agent with demonstrated efficacy across diverse radiation-injured organs, highlighting its significance as an effective and potent antioxidant that affordable for most patients. Abundant experiments have exhibited the capacity of selenium-containing compounds and metabolites to function as valuable radioprotective adjuvants, emphasizing their potential in safeguarding against the adverse effects of radiation exposure. To harness the full radioprotective potential of selenium, further research to optimize selenium supplementation strategies is in need, taking into account factors such as timing and dosage, particularly in the context of radiotherapy.
核技术的多方面应用,特别是通过放射疗法进行癌症治疗,给我们的日常生活带来了巨大的好处,但同时也要求我们必须采取有效的策略,以有效缓解辐射引起的问题。严格遵守使用规范固然重要,但确保对辐射引起的损害进行适当防护也至关重要。硒以各种形式(包括硒代蛋氨酸、依布硒和亚硒酸钠)出现,是一种很有前途的辐射防护剂,对各种辐射损伤器官都有明显疗效,突出了其作为一种有效和强效抗氧化剂的重要意义,大多数患者都能负担得起。大量实验表明,含硒化合物和代谢物有能力发挥宝贵的辐射防护辅助剂的作用,强调了它们在防止辐射照射不良影响方面的潜力。为了充分发挥硒的放射保护潜力,需要进一步研究如何优化补硒策略,同时考虑到时间和剂量等因素,尤其是在放疗的情况下。
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引用次数: 0
Relationship between radiation dose indices and patient size in adult brain computed tomography 成人脑计算机断层扫描中辐射剂量指数与患者体型的关系
Pub Date : 2024-08-08 DOI: 10.1051/radiopro/2024033
K. Mitsui, Y. Inoue, H. Itoh, H. Hata, H. Miyatake, T. Yamane
The relationship between radiation dose indices and patient size was investigated in adult brain CT scans to assess the significance of considering the patient size for radiation dose management. Two hundred patients who underwent brain CT using automatic exposure control were enrolled. The radiation dose indices (volume CT dose index, CTDIvol; size-specific dose estimate, SSDE; dose length product, DLP) were compared with the head size indices (effective diameter, ED; water-equivalent diameter, WED) and body weight. The CTDIvol and SSDE correlated positively with the ED and WED. The correlations were higher for the WED than the ED and for the CTDIvol than the SSDE. Although the DLP also correlated positively with the ED and the WED, the correlations were lower than those for the CTDIvol and the SSDE. The CTDIvol and SSDE showed significant positive correlations with body weight, but the correlations were lower than those for the ED. In conclusion, the radiation dose indices in adult brain CT correlate with the head size indices. Consideration of the head size indices is recommended for radiation dose management in brain CT. The relationship between the radiation dose indices and body weight may be of some significance when the head size indices are not readily available.
研究了成人脑部 CT 扫描中辐射剂量指数与患者体型之间的关系,以评估考虑患者体型对辐射剂量管理的意义。200 名患者接受了使用自动曝光控制的脑 CT 扫描。辐射剂量指数(体积 CT 剂量指数,CTDIvol;特定体型剂量估计值,SSDE;剂量长度乘积,DLP)与头部尺寸指数(有效直径,ED;水当量直径,WED)和体重进行了比较。CTDIvol 和 SSDE 与 ED 和 WED 呈正相关。WED 的相关性高于 ED,CTDIvol 的相关性高于 SSDE。虽然 DLP 也与 ED 和 WED 呈正相关,但相关性低于 CTDIvol 和 SSDE。CTDIvol 和 SSDE 与体重呈显著正相关,但相关性低于 ED。总之,成人脑 CT 的辐射剂量指数与头部尺寸指数相关。建议在脑部 CT 辐射剂量管理中考虑头部尺寸指数。在无法获得头部尺寸指数的情况下,辐射剂量指数与体重之间的关系可能具有一定意义。
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引用次数: 0
Assessing Biological Risks: Knowledge, approach, and Perceptions of Dental Students Towards Ionizing Radiation in Dentistry. 评估生物风险:牙科学生对牙科电离辐射的认识、方法和看法。
Pub Date : 2024-06-09 DOI: 10.1051/radiopro/2024021
W. Ageeli, T. R. A. Alfaify, E. Abdali, A. Sharafy, A. Gissy, M. Ageeli, A. Alyami, A. Abdelrazig, N. Abohadi, B. Ageeli, B. Alwadani, A. Ageeli, N. Majrashi
Background: Dental radiography, a pivotal diagnostic technique in dentistry, plays a significant role in patient care. Despite its indispensability, the use of ionizing radiation in dental radiography entails inherent risks. Dental students, as future practitioners, bear the responsibility of acquiring thorough knowledge in radiation protection to ensure the safety of both patients and operators. Aim: This study seeks to evaluate the levels of awareness, knowledge, and approach regarding ionizing radiation among dental students enrolled in the dentistry program at Jazan university (JU). Material and Methods: A descriptive, cross-sectional survey was carried out involving 82 dental students, with a participant distribution of 63 males (77%) and 19 females (23%) across different academic years. The survey utilized a structured questionnaire designed to assess awareness regarding deterministic and stochastic effects of ionizing radiation, as well as various aspects of radiation protection practices. Demographic factors, including gender and academic year, were scrutinized for their potential impact on radiation protection awareness. The collected data underwent statistical analysis using chi-square tests implemented in SPSS to explore any significant associations. Results: The study included 82 dental students with varying age distributions. Age-wise, 39% fell within the 21-23 years range, 31% were between 18-20 years, 24% ranged from 24 to 26 years, and 6% were older than 26 years. Participants were distributed across different academic years, with the largest group being fourth-year students (25%), followed by fifth-year students (15%). Female students exhibited higher awareness of the National Council on Radiation Protection (NCRP) and International Commission on Radiological Protection (ICRP) recommendations, and the practice of standing behind lead barriers during exposure. Conclusion: This study underscores the overall elevated awareness and knowledge regarding radiation protection among dental students. Nevertheless, distinct gender-related variations in specific facets of awareness were identified, underscoring the necessity for targeted educational interventions. The findings support the integration of comprehensive radiation safety education into dental curricula, aimed at fostering responsible utilization of radiographic procedures and ensuring the well-being of both patients and operators.
背景:牙科射线照相术是牙科的一项重要诊断技术,在病人护理中发挥着重要作用。尽管它不可或缺,但在牙科放射摄影中使用电离辐射会带来固有的风险。牙科学生作为未来的从业人员,有责任掌握全面的辐射防护知识,以确保患者和操作人员的安全。目的:本研究旨在评估贾赞大学(JU)牙科专业学生对电离辐射的认识水平、知识和方法。材料与方法:对 82 名牙科学生进行了描述性横断面调查,不同学年的参与者分布为 63 名男生(77%)和 19 名女生(23%)。调查采用了结构化问卷,旨在评估学生对电离辐射的确定性和随机性影响以及辐射防护实践各个方面的认识。对包括性别和学年在内的人口统计学因素进行了仔细研究,以了解其对辐射防护意识的潜在影响。收集到的数据使用 SPSS 中的卡方检验进行了统计分析,以探讨任何重要的关联。研究结果研究包括 82 名年龄分布各异的牙科学生。从年龄上看,39%的学生年龄在 21-23 岁之间,31%的学生年龄在 18-20 岁之间,24%的学生年龄在 24-26 岁之间,6%的学生年龄在 26 岁以上。参与者分布在不同的学年,其中最多的是四年级学生(25%),其次是五年级学生(15%)。女生对美国国家辐射防护委员会(NCRP)和国际辐射防护委员会(ICRP)的建议以及在照射时站在铅屏障后面的做法有更高的认识。 结论这项研究强调了牙科学生对辐射防护的整体认识和知识水平的提高。然而,在意识的特定方面,发现了与性别相关的明显差异,这突出了采取有针对性的教育干预措施的必要性。研究结果支持将全面的辐射安全教育纳入牙科课程,旨在培养学生负责任地使用放射摄影程序,确保患者和操作者的健康。
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引用次数: 0
La rationalisation de la radioprotection à l’époque des pionniers du nucléaire 核先锋时代的辐射防护合理化
Pub Date : 2024-04-22 DOI: 10.1051/radiopro/2024015
A. Portelli
Le centre nucléaire de Marcoule, mis en service en 1955 par le CEA, accueille les premiers réacteurs français de dimension industrielle. Leur exploitation pose un immense défi en matière de sécurité radiologique, auquel répond la création du Service de Protection contre les Radiations (SPR). Ce dernier rationalise la radioprotection et élabore sa doctrine en même temps qu’il développe ses moyens de contrôle et de surveillance. Conscient de l’ampleur de sa mission, le SPR cherche à réduire sa tâche en promouvant la contribution active du personnel à sa propre protection. Pour ce faire, il développe un programme d'éducation en matière de risque radioactif. Celui-ci est destiné aux agents de Marcoule, mais aussi au grand public, parmi lequel sont recrutés les travailleurs du nucléaire. Ce programme éducatif, illustré par le dessinateur Jacques Castan, participe ainsi de l’effort de rationalisation de la radioprotection entrepris par le SPR.
马尔库尔核反应堆中心于 1955 年由法国原子能委员会(CEA)建成,是法国第一批工业规模的反应堆所在地。反应堆的运行给辐射安全带来了巨大挑战,为此成立了辐射防护部(SPR)。辐射防护部在发展其控制和监测资源的同时,还对辐射防护进行了合理化改革并制定了相关理论。辐射防护部意识到其使命的广泛性,力求通过促进工作人员对自身防护的积极贡献来减少其工作量。为此,它正在制定一项放射性风险教育计划。该计划不仅面向马尔库尔的工作人员,也面向公众,因为核工作人员就是从公众中招聘的。这项教育计划由漫画家雅克-卡斯坦(Jacques Castan)绘制插图,是 SPR 开展的辐射防护合理化工作的一部分。
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引用次数: 0
Radiographers’ attitudes toward the principles of patient radiation protection in the Souss Massa region of Morocco 摩洛哥 Souss Massa 地区放射技师对患者辐射防护原则的态度
Pub Date : 2024-04-22 DOI: 10.1051/radiopro/2024014
M. El Fahssi, S. Semghouli, B. Amaoui, J. EL KHALLADI, M. ÇAOUI, L. Jroundi
Introduction: Radiographers play a vital role in patient radiation protection. Their training, supervision, and involvement in radiation protection programmes require greater attention from all stakeholders. Methods: This cross-sectional study was conducted between March and August 2023 to assess Radiographers’ attitudes toward the principles of patient radiation protection in the Souss Massa region of Morocco. An anonymous questionnaire containing 22 questions was sent to 80 radiographers practicing in the Sous Massa region. Results: 67.5% of the radiographers confirmed that they did not use a guide to radiological procedures. 85% of them confirmed that they had checked for the possibility of pregnancy each time a woman of childbearing age was involved in a conventional X-ray, compared with 97.5% who checked for the possibility of pregnancy in a CT scan. 97.5 % of our participants said that they automatically (without medical advice) repeated the X-ray examination if the image was not interpretable. 90% of radiographers said that they did not report parameters for dose estimation for each conventional X-ray examination, and 72.5% did not report data for dose estimation for CT-scan examinations. The results showed no association between gender and professional experience on the one hand and radiographers' practices on the other. Nevertheless, there is an association between the workplace and certain radiographers' practices, indicating the lack of a regional strategy aimed at standardizing procedures and radiation protection practices at the level of all radiology departments. Conclusion: It is vital to launch a patient dose management program in the Souss Massa region and campaigns to raise radiographers’ awareness of recommended patient radiation protection practices.
导言:放射技师在患者辐射防护方面发挥着至关重要的作用。他们的培训、监督和参与辐射防护计划需要所有利益相关者给予更多关注。研究方法这项横断面研究于 2023 年 3 月至 8 月间进行,旨在评估摩洛哥 Souss Massa 地区的放射技师对患者辐射防护原则的态度。研究人员向在 Sous Massa 地区执业的 80 名放射技师发送了一份包含 22 个问题的匿名调查问卷。结果显示67.5%的放射技师确认他们没有使用放射程序指南。其中 85% 的放射技师确认,每次为育龄妇女进行常规 X 光检查时,他们都会检查是否有怀孕的可能,而 97.5% 的放射技师在进行 CT 扫描时会检查是否有怀孕的可能。97.5%的参与者表示,如果图像无法解读,他们会自动(在没有医嘱的情况下)重复 X 光检查。90% 的放射技师表示,他们没有报告每次常规 X 光检查的剂量估算参数,72.5% 的放射技师没有报告 CT 扫描检查的剂量估算数据。结果显示,性别和专业经验与放射技师的工作方法之间没有关联。不过,工作场所与某些放射技师的做法之间存在关联,这表明缺乏一项旨在统一所有放射科的程序和辐射防护做法的地区性战略。结论:在 Souss Massa 地区启动患者剂量管理计划和开展宣传活动,提高放射技师对建议的患者辐射防护措施的认识至关重要。
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引用次数: 0
Measurement of Some Natural Radioactive Isotopes Concentrations in Soil Samples in the Northern Part of West Bank - Palestine 测量巴勒斯坦约旦河西岸北部土壤样本中的某些天然放射性同位素浓度
Pub Date : 2024-04-22 DOI: 10.1051/radiopro/2024012
Khalil M. Thabayneh, Rounz J. Shawamreh
In this specific study, the concentration of radon, radium content, and annual effective dose were meticulously measured and calculated utilizing solid-state nuclear track detectors (CR-39). The research was centered on soil samples extracted from diverse locations in the northern regions of the West Bank, Palestine. A comprehensive set of 40 soil samples was systematically collected from Tulkarm, Jenin, and Tubas Governorates. The average concentrations of 222Rn and 226Ra in Tulkarm, Jenin, and Tubas governorates were found to be 505.2 Bq/m³ and 22.0 Bq/kg; 528.4 Bq/m³ and 23.1 Bq/kg; and 515.3 Bq/m³ and 22.5 Bq/kg, respectively. Calculating the overall total average effective dose for these governorates yielded values of 17.5, 18.3, and 17.8 mSv/year, respectively. These values slightly exceed the action levels (3-10 mSv/year) recommended by ICRP-1993. It's noteworthy that the measurements established in this study provide a foundational database of activity levels, serving as a reference for future studies assessing the potential impacts of events to come.
在这项具体研究中,利用固态核轨道探测器(CR-39)对氡浓度、镭含量和年有效剂量进行了细致的测量和计算。研究以从巴勒斯坦约旦河西岸北部地区不同地点提取的土壤样本为中心。从图勒凯尔姆、杰宁和图巴斯省系统收集了 40 份土壤样本。发现图勒凯尔姆、杰宁和图巴斯省的 222Rn 和 226Ra 平均浓度分别为 505.2 Bq/m³ 和 22.0 Bq/kg;528.4 Bq/m³ 和 23.1 Bq/kg;以及 515.3 Bq/m³ 和 22.5 Bq/kg。计算这些省份的总平均有效剂量得出的数值分别为 17.5、18.3 和 17.8 mSv/年。这些数值略微超过了 ICRP-1993 建议的行动水平(3-10 mSv/年)。值得注意的是,这项研究中确定的测量值提供了一个活动水平的基础数据库,可作为未来研究评估未来事件潜在影响的参考。
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引用次数: 0
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Radioprotection
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