Pub Date : 2023-12-28DOI: 10.56501/intjclinicopatholcorrel.v7i2.956
Narendran A
Squamous cell carcinoma (SCC) affecting the tongue commonly emerges along its lateral border, yet occurrences specifically on the dorsum, especially at the midline, are notably rare. This study delves into the incidence rates of SCC localized on the tongue, alongside an investigation into simultaneous lesions of the breast. 50-year-old female presented with an ulcerative growth on the left side of the tongue, accompanied by speech difficulty and chewing discomfort persisting for a month. Previous history included breast surgery five years prior, along with ongoing diabetes medication. No history of habits, trauma, or prior ulcer formation was reported. Clinical examination revealed a whitish-yellow, firm, ulcerative lesion extending on the left lateral tongue surface, measuring 7.2x3.1x2.5cm with an exophytic growth of 4.7x2.1cm. The lesion, extending to the dorsal tongue surface, displayed erythematous flooring interspersed with slough and pale mucosa. Limited tongue movement and palpable submandibular nodes were noted. Initial diagnostic findings indicated stage IV metastatic carcinoma of the tongue (T4aN2M1). pathology revealed severe epithelial dysplasia with an invasive pattern in the form of islands, demonstrating altered cellular features, pleomorphism, inflammatory infiltrate, vascularity, and areas of hemorrhage. Lymph nodal analysis showed metastatic deposits in one of three left level II B lymph nodes.
影响舌头的鳞状细胞癌(SCC)通常出现在舌头的外侧边界,但发生在舌背,尤其是中线的情况却非常罕见。本研究深入探讨了舌局部 SCC 的发病率,同时还对乳房的同期病变进行了调查。50 岁女性患者的舌头左侧出现溃疡性增生,并伴有持续一个月的语言障碍和咀嚼不适。既往史包括五年前的乳房手术,以及正在服用的糖尿病药物。无习惯史、外伤史或溃疡形成史。临床检查发现,患者舌头左外侧表面有一个白黄色、坚硬的溃疡性病变,大小为 7.2x3.1x2.5 厘米,外生殖物为 4.7x2.1 厘米。病变延伸到舌背表面,显示出红斑,其间夹杂着溃疡和苍白的粘膜。舌头活动受限,可触及颌下结节。初步诊断结果显示为舌转移性癌 IV 期(T4aN2M1)。病理检查显示上皮严重发育不良,呈岛屿状浸润,细胞特征改变,多形性,炎症浸润,血管丰富,并有出血区域。淋巴结分析显示,左侧三个二级 B 淋巴结中有一个出现转移沉积。
{"title":"A case report on the simultaneous occurrence of cancer in The Tongue and Breast","authors":"Narendran A","doi":"10.56501/intjclinicopatholcorrel.v7i2.956","DOIUrl":"https://doi.org/10.56501/intjclinicopatholcorrel.v7i2.956","url":null,"abstract":"Squamous cell carcinoma (SCC) affecting the tongue commonly emerges along its lateral border, yet occurrences specifically on the dorsum, especially at the midline, are notably rare. This study delves into the incidence rates of SCC localized on the tongue, alongside an investigation into simultaneous lesions of the breast. 50-year-old female presented with an ulcerative growth on the left side of the tongue, accompanied by speech difficulty and chewing discomfort persisting for a month. Previous history included breast surgery five years prior, along with ongoing diabetes medication. No history of habits, trauma, or prior ulcer formation was reported. Clinical examination revealed a whitish-yellow, firm, ulcerative lesion extending on the left lateral tongue surface, measuring 7.2x3.1x2.5cm with an exophytic growth of 4.7x2.1cm. The lesion, extending to the dorsal tongue surface, displayed erythematous flooring interspersed with slough and pale mucosa. Limited tongue movement and palpable submandibular nodes were noted. Initial diagnostic findings indicated stage IV metastatic carcinoma of the tongue (T4aN2M1). pathology revealed severe epithelial dysplasia with an invasive pattern in the form of islands, demonstrating altered cellular features, pleomorphism, inflammatory infiltrate, vascularity, and areas of hemorrhage. Lymph nodal analysis showed metastatic deposits in one of three left level II B lymph nodes.","PeriodicalId":507732,"journal":{"name":"International Journal of Clinicopathological Correlation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139151416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}