Pub Date : 2024-07-15DOI: 10.1097/js9.0000000000001932
Xiwen Ye, Xiaoya Niu, Dan Bai, Yu Cao, Xiaoling Mao, Huizhen Liu, Yuting Luo, Fuyu-Li, Nansheng Cheng, Zhen You
Postoperative pain after laparoscopic cholecystectomy (LC) is the most frequent postoperative complaint. To date, gallbladder extraction via the subxiphoid port (SXP) versus the supraumbilical port (SUP) is still controversial. Thus, we performed this randomized controlled trial to compare postoperative pain between the SXP and SUP for LC. From June 2021 to June 2023, patients who met the inclusion criteria were randomly assigned to two groups. The perioperative data of both groups were recorded and compared. A total of 253 patients were enrolled in the analysis. There were 126 in the SXP group and 127 in the SUP group. There was no significant difference between the two groups in terms of the duration of gallbladder extraction, whether the incision was extended, the least rate of pain, the average rate of pain, the right-now rate of pain, postoperative pain on the 5th, 7th, and 14th days, postoperative complications and Vancouver Scar scale (VSS). However, the SUP group had a lower the worst rate of pain (4.24±2.45 vs. 4.91±2.45, P=0.031) and 3 days of pain (3.35±1.57 vs. 3.75±1.52, P=0.045) than did the SXP group. The influence of pain on general activity (4.51±2.90 vs. 3.76±2.92, P=0.041), mood (3.62±2.66 vs. 2.92±2.36, P=0.028), walking ability (4.40±3.01 vs. 3.66±2.76, P=0.044), and enjoyment of life (3.19±2.68 vs. 2.32±2.34, P=0.007) in the SXP was more severe than that in the SUP. The extraction of the gallbladder via the SUP is superior to that via the SXP because the early postoperative 24-hour pain and pain on the third day are mild and do not increase the duration of gallbladder extraction or the risk of infection or hernia.
腹腔镜胆囊切除术（LC）术后疼痛是最常见的术后主诉。迄今为止，通过剑突下切口（SXP）和脐上切口（SUP）进行胆囊摘除术仍存在争议。因此，我们进行了这项随机对照试验，以比较剑突下孔和脐上孔胆囊摘除术的术后疼痛。 从 2021 年 6 月到 2023 年 6 月，符合纳入标准的患者被随机分配到两组。我们记录并比较了两组患者的围手术期数据。 共有 253 名患者参与了分析。SXP组有126人，SUP组有127人。两组患者在胆囊摘除术持续时间、是否延长切口、最少疼痛率、平均疼痛率、即刻疼痛率、术后第 5 天、第 7 天和第 14 天疼痛、术后并发症和温哥华疤痕量表（VSS）方面无明显差异。然而，SUP 组的最严重疼痛率（4.24±2.45 vs. 4.91±2.45，P=0.031）和术后 3 天疼痛率（3.35±1.57 vs. 3.75±1.52，P=0.045）均低于 SXP 组。疼痛对一般活动（4.51±2.90 vs. 3.76±2.92，P=0.041）、情绪（3.62±2.66 vs. 2.92±2.36，P=0.028）、行走能力（4.40±3.01 vs. 3.66±2.76，P=0.044）和生活乐趣（3.19±2.68 vs. 2.32±2.34，P=0.007）的影响，SXP 组比 SUP 组更严重。 经 SUP 切除胆囊优于经 SXP 切除胆囊，因为术后早期 24 小时疼痛和术后第三天疼痛轻微，不会增加胆囊切除时间或感染或疝的风险。
{"title":"Comparison of gallbladder extraction via the subxiphoid port and the supraumbilical port during laparoscopic cholecystectomy: a prospective randomized clinical trial","authors":"Xiwen Ye, Xiaoya Niu, Dan Bai, Yu Cao, Xiaoling Mao, Huizhen Liu, Yuting Luo, Fuyu-Li, Nansheng Cheng, Zhen You","doi":"10.1097/js9.0000000000001932","DOIUrl":"https://doi.org/10.1097/js9.0000000000001932","url":null,"abstract":"\u0000 \u0000 Postoperative pain after laparoscopic cholecystectomy (LC) is the most frequent postoperative complaint. To date, gallbladder extraction via the subxiphoid port (SXP) versus the supraumbilical port (SUP) is still controversial. Thus, we performed this randomized controlled trial to compare postoperative pain between the SXP and SUP for LC.\u0000 \u0000 \u0000 \u0000 From June 2021 to June 2023, patients who met the inclusion criteria were randomly assigned to two groups. The perioperative data of both groups were recorded and compared.\u0000 \u0000 \u0000 \u0000 A total of 253 patients were enrolled in the analysis. There were 126 in the SXP group and 127 in the SUP group. There was no significant difference between the two groups in terms of the duration of gallbladder extraction, whether the incision was extended, the least rate of pain, the average rate of pain, the right-now rate of pain, postoperative pain on the 5th, 7th, and 14th days, postoperative complications and Vancouver Scar scale (VSS). However, the SUP group had a lower the worst rate of pain (4.24±2.45 vs. 4.91±2.45, P=0.031) and 3 days of pain (3.35±1.57 vs. 3.75±1.52, P=0.045) than did the SXP group. The influence of pain on general activity (4.51±2.90 vs. 3.76±2.92, P=0.041), mood (3.62±2.66 vs. 2.92±2.36, P=0.028), walking ability (4.40±3.01 vs. 3.66±2.76, P=0.044), and enjoyment of life (3.19±2.68 vs. 2.32±2.34, P=0.007) in the SXP was more severe than that in the SUP.\u0000 \u0000 \u0000 \u0000 The extraction of the gallbladder via the SUP is superior to that via the SXP because the early postoperative 24-hour pain and pain on the third day are mild and do not increase the duration of gallbladder extraction or the risk of infection or hernia.\u0000","PeriodicalId":507793,"journal":{"name":"International Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141649105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-08DOI: 10.1097/js9.0000000000001948
Mai Abdel Haleem Abusalah, Priyanka, Engku Nur Syafirah Engku Abd Rahman, O. Choudhary
Stem cell therapy is growing in popularity as a form of regenerative medicine with the capacity to treat a wide range of ailments. Stem cells exhibit the ability to differentiate into a diverse array of cell types within the organism due to their undifferentiated state. These cell sources include bone marrow, induced pluripotent stem cells, and umbilical cord tissue 1. Significant advancements in clinical applications and fundamental research of stem cells in regenerative medicine and other domains have occurred in recent years, motivating individuals to delve deeper into the study of stem cells. Stem cells, owing to their virtually limitless capacity for self-renewal, offer vast potential for advancements in the treatment of various diseases and human organ damage. Stem cell-related technologies for induction and isolation are relatively developed in the field of stem cell research, and numerous stable stem cell lines have been constructed with outstanding results 2. This editorial will delve into the latest advancements in stem cell therapy, shedding light on key developments, their clinical applications, and the promising future prospects.
{"title":"Evolving trends in stem cell therapy: an emerging and promising approach against various diseases","authors":"Mai Abdel Haleem Abusalah, Priyanka, Engku Nur Syafirah Engku Abd Rahman, O. Choudhary","doi":"10.1097/js9.0000000000001948","DOIUrl":"https://doi.org/10.1097/js9.0000000000001948","url":null,"abstract":"Stem cell therapy is growing in popularity as a form of regenerative medicine with the capacity to treat a wide range of ailments. Stem cells exhibit the ability to differentiate into a diverse array of cell types within the organism due to their undifferentiated state. These cell sources include bone marrow, induced pluripotent stem cells, and umbilical cord tissue 1. Significant advancements in clinical applications and fundamental research of stem cells in regenerative medicine and other domains have occurred in recent years, motivating individuals to delve deeper into the study of stem cells. Stem cells, owing to their virtually limitless capacity for self-renewal, offer vast potential for advancements in the treatment of various diseases and human organ damage. Stem cell-related technologies for induction and isolation are relatively developed in the field of stem cell research, and numerous stable stem cell lines have been constructed with outstanding results 2. This editorial will delve into the latest advancements in stem cell therapy, shedding light on key developments, their clinical applications, and the promising future prospects.","PeriodicalId":507793,"journal":{"name":"International Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141668546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-25DOI: 10.1097/js9.0000000000001416
Yingying Ding, Ming Qi, Jirong Dong, Da Wu
{"title":"A commentary on “A dynamic nomogram for predicting intraoperative brain bulge during decompressive craniectomy in patients with traumatic brain injury: a retrospective study”","authors":"Yingying Ding, Ming Qi, Jirong Dong, Da Wu","doi":"10.1097/js9.0000000000001416","DOIUrl":"https://doi.org/10.1097/js9.0000000000001416","url":null,"abstract":"","PeriodicalId":507793,"journal":{"name":"International Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-18DOI: 10.1097/js9.0000000000001259
Aimin Jiang, Le Qu, Peng Luo, Linhui Wang
{"title":"A commentary on “Risk factors for incident venous thromboembolism in patients with renal tumor and inferior vena cava tumor thrombus: a retrospective case–control study”","authors":"Aimin Jiang, Le Qu, Peng Luo, Linhui Wang","doi":"10.1097/js9.0000000000001259","DOIUrl":"https://doi.org/10.1097/js9.0000000000001259","url":null,"abstract":"","PeriodicalId":507793,"journal":{"name":"International Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140233052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objectives: This study aimed to assess the influence of abdominal computerized tomography (CT) scans on the management of children presenting with acute abdominal conditions, considering concerns regarding radiation exposure. Methods: A retrospective review was conducted of all acute pediatric patients who underwent abdominal CT in a tertiary hospital, during 2018-2019. Results: Over the 2-year period, 976 pediatric patients were admitted due to acute abdominal conditions. Of 197 (20.2%) patients who underwent abdominal CT scans, management plan was modified based on CT results in 67.5%. In non-trauma cases, the impact on the management plan was even more pronounced, affecting 91.2% of patients, and led to invasive procedures (one third), non-invasive actions (one third), or discharge (one third). Multivariate analysis demonstrated a significantly higher odds ratios (OR) for impact on management in non-trauma patients (OR=24) as compared to trauma patients, especially younger (OR=1.58 annually) and male (OR=10.42) patients, and when performed early (OR=2.44, for each day earlier). Trauma patients with a lower body mass index (BMI) (OR=1.02 per percentile decrease) demonstrated a significantly larger impact. Conclusion: These results support a more liberal use of early CT scans in non-traumatic acute pediatric abdominal conditions, especially in younger male patients, with more careful consideration in trauma patients, particularly those with high BMIs.
{"title":"The Role of Abdominal CT in the Management of Acute Abdominal Conditions in Children","authors":"Osnat Zmora, Atara Indursky, Gal Becker, Netanel Agajany, Rachel Aber, Vasilina Kaminsky","doi":"10.60122/j.ijs.2023.40.04","DOIUrl":"https://doi.org/10.60122/j.ijs.2023.40.04","url":null,"abstract":"Objectives: This study aimed to assess the influence of abdominal computerized tomography (CT) scans on the management of children presenting with acute abdominal conditions, considering concerns regarding radiation exposure. Methods: A retrospective review was conducted of all acute pediatric patients who underwent abdominal CT in a tertiary hospital, during 2018-2019. Results: Over the 2-year period, 976 pediatric patients were admitted due to acute abdominal conditions. Of 197 (20.2%) patients who underwent abdominal CT scans, management plan was modified based on CT results in 67.5%. In non-trauma cases, the impact on the management plan was even more pronounced, affecting 91.2% of patients, and led to invasive procedures (one third), non-invasive actions (one third), or discharge (one third). Multivariate analysis demonstrated a significantly higher odds ratios (OR) for impact on management in non-trauma patients (OR=24) as compared to trauma patients, especially younger (OR=1.58 annually) and male (OR=10.42) patients, and when performed early (OR=2.44, for each day earlier). Trauma patients with a lower body mass index (BMI) (OR=1.02 per percentile decrease) demonstrated a significantly larger impact. Conclusion: These results support a more liberal use of early CT scans in non-traumatic acute pediatric abdominal conditions, especially in younger male patients, with more careful consideration in trauma patients, particularly those with high BMIs.","PeriodicalId":507793,"journal":{"name":"International Journal of Surgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139197139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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