Sakshi K. Nerkar, Rashmi Hedge, Nida Shaikh, Neha Langade
The purpose of this study was to assess the efficacy of (Light-Activated) Photodynamic therapy in extraction socket disinfection. The goal is to assess the quantitative and qualitative changes in microbial load following the use of photodynamic therapy in extraction socket disinfection. This study included 20 patients ranging in age from 18 to 55 years who required extraction of non-restorable teeth or those with periapical lesions. Extraction was done under local anesthesia, following the principles of atraumatic extraction for socket preservation. Pre-operative samples were collected with paper points for real-time polymerase chain reaction (PCR) analysis. A photosensitizer, Methylene blue dye, was applied for 60 seconds. The PDT laser (660nm) was used for a total of 3 minutes, with 20 second intervals. Following PDT application, repeat samples were collected for PCR analysis to determine the bactericidal effect in socket disinfection. The results showed a predominance of P. gingivalis, a potential periodontal pathogen, and a significant reduction in the same following the application of light activated PDT. Photodynamic therapy has demonstrated promising bactericidal effects, which can improve postoperative outcomes and be considered as one treatment option for immediate implants in infected sockets.
{"title":"A PCR based study to evaluate the effectiveness of photodynamic therapy in extraction socket disinfection","authors":"Sakshi K. Nerkar, Rashmi Hedge, Nida Shaikh, Neha Langade","doi":"10.4081/ltj.2024.394","DOIUrl":"https://doi.org/10.4081/ltj.2024.394","url":null,"abstract":"The purpose of this study was to assess the efficacy of (Light-Activated) Photodynamic therapy in extraction socket disinfection. The goal is to assess the quantitative and qualitative changes in microbial load following the use of photodynamic therapy in extraction socket disinfection. This study included 20 patients ranging in age from 18 to 55 years who required extraction of non-restorable teeth or those with periapical lesions. Extraction was done under local anesthesia, following the principles of atraumatic extraction for socket preservation. Pre-operative samples were collected with paper points for real-time polymerase chain reaction (PCR) analysis. A photosensitizer, Methylene blue dye, was applied for 60 seconds. The PDT laser (660nm) was used for a total of 3 minutes, with 20 second intervals. Following PDT application, repeat samples were collected for PCR analysis to determine the bactericidal effect in socket disinfection. The results showed a predominance of P. gingivalis, a potential periodontal pathogen, and a significant reduction in the same following the application of light activated PDT. Photodynamic therapy has demonstrated promising bactericidal effects, which can improve postoperative outcomes and be considered as one treatment option for immediate implants in infected sockets.","PeriodicalId":507900,"journal":{"name":"Laser Therapy","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141682739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antonio Leccisotti, Stefania V. Fields, G. De Bartolo, Christian Crudale, Matteo Posarelli
Correcting refractive errors by remodeling the corneal curvature with an excimer laser (which emits ultraviolet radiation) may reactivate a latent Herpes Simplex Virus (HSV), resulting in keratitis. New techniques using infrared sources, such as femtosecond-assisted Keratorefractive Lenticule Extraction (KLEx), may thus provide a safer approach to eyes with previous HSV keratitis; however, no cases of KLEx in such cases have been reported. As a result, we present three cases in which KLEx successfully corrected myopia. Three myopic eyes from three patients with a known history of healed HSV keratitis that occurred more than 12 months before surgery underwent KLEx. All patients received oral antiviral prophylaxis before and after surgery. In case 1, the post-HSV scar was semiperipheral, involving only a portion of the treated area; surgery went smoothly, with the intrastromal lenticule well delineated and dissected even through the scar. In cases 2 and 3, the healed scar was peripheral and did not interfere with surgery. After 6 months, all three cases had good visual acuity without complications. Finally, KLEx combined with antiviral prophylaxis can effectively correct myopia in eyes with healed HSV. The femtosecond laser can penetrate non-dense, peripheral corneal scars.
{"title":"Keratorefractive lenticule extraction in eyes with post-herpetic scars","authors":"Antonio Leccisotti, Stefania V. Fields, G. De Bartolo, Christian Crudale, Matteo Posarelli","doi":"10.4081/ltj.2024.397","DOIUrl":"https://doi.org/10.4081/ltj.2024.397","url":null,"abstract":"Correcting refractive errors by remodeling the corneal curvature with an excimer laser (which emits ultraviolet radiation) may reactivate a latent Herpes Simplex Virus (HSV), resulting in keratitis. New techniques using infrared sources, such as femtosecond-assisted Keratorefractive Lenticule Extraction (KLEx), may thus provide a safer approach to eyes with previous HSV keratitis; however, no cases of KLEx in such cases have been reported. As a result, we present three cases in which KLEx successfully corrected myopia. Three myopic eyes from three patients with a known history of healed HSV keratitis that occurred more than 12 months before surgery underwent KLEx. All patients received oral antiviral prophylaxis before and after surgery. In case 1, the post-HSV scar was semiperipheral, involving only a portion of the treated area; surgery went smoothly, with the intrastromal lenticule well delineated and dissected even through the scar. In cases 2 and 3, the healed scar was peripheral and did not interfere with surgery. After 6 months, all three cases had good visual acuity without complications. Finally, KLEx combined with antiviral prophylaxis can effectively correct myopia in eyes with healed HSV. The femtosecond laser can penetrate non-dense, peripheral corneal scars.","PeriodicalId":507900,"journal":{"name":"Laser Therapy","volume":"345 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141691624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Shahabi, Alireza Tabatabaeian, Luca Solimei, Stefano Benedicenti, S. Saberi
Considering the increasing use of esthetic treatments, one of which is bleaching treatment, choosing the different wavelengths and parameters for this treatment can help in choosing the best treatment. Based on this, this study aimed to investigate bleaching with three wavelengths of 445nm, 915nm, and 970 nm on the amount of teeth discoloration. In this study, 77 human permanent teeth without caries were selected and randomly divided into 7 groups as control, 445 nm (1 and 1.5 W and time 20 seconds), 915 nm (2 and 2.5 W and time 30 seconds) and 970 nm (1.5 and 2 W and time 30 seconds). The bleaching gel used was 40% hydrogen peroxide bleaching gel(Ultradent-Opalescence, USA). All groups were subjected to laser irradiation with a 0.5 cm2 area with continuous wave mode radiation at a distance of 1 mm from the bleaching gel. Before starting the study, all the samples were subjected to calorimetry using a spectrophotometer. After bleaching with the said wavelengths, Color change data on the CIE L * a * b* system was analyzed statistically by the one-way ANOVA and Tukey’s HSD test. Based on the findings, ΔE was positive in all groups. The highest amount was in the 445nm 1.5w group and the lowest was seen in the control group and then in the 970nm 2w group (P<0.05). The highest dispersion of color change is related to the 445nm 1.5w group (P<0.05). In general, the results showed that the use of 445nm diode laser 1.5w (ΔE=12) and 970nm diode laser 2w (ΔE=37.5) was the most and least effective in teeth bleaching, respectively. According to the results of the present Invitro study, the 445 nm laser with a power of 1.5 watts had the most effect in changing tooth color, and the 970 nm group with a power of 2 watts showed the least effect.
{"title":"Effect of laser-activated bleaching with 445, 915, and 970nm diode lasers on enamel color change: an in vitro study","authors":"S. Shahabi, Alireza Tabatabaeian, Luca Solimei, Stefano Benedicenti, S. Saberi","doi":"10.4081/ltj.2024.391","DOIUrl":"https://doi.org/10.4081/ltj.2024.391","url":null,"abstract":" \u0000 Considering the increasing use of esthetic treatments, one of which is bleaching treatment, choosing the different wavelengths and parameters for this treatment can help in choosing the best treatment. Based on this, this study aimed to investigate bleaching with three wavelengths of 445nm, 915nm, and 970 nm on the amount of teeth discoloration. In this study, 77 human permanent teeth without caries were selected and randomly divided into 7 groups as control, 445 nm (1 and 1.5 W and time 20 seconds), 915 nm (2 and 2.5 W and time 30 seconds) and 970 nm (1.5 and 2 W and time 30 seconds). The bleaching gel used was 40% hydrogen peroxide bleaching gel(Ultradent-Opalescence, USA). All groups were subjected to laser irradiation with a 0.5 cm2 area with continuous wave mode radiation at a distance of 1 mm from the bleaching gel. Before starting the study, all the samples were subjected to calorimetry using a spectrophotometer. After bleaching with the said wavelengths, Color change data on the CIE L * a * b* system was analyzed statistically by the one-way ANOVA and Tukey’s HSD test. Based on the findings, ΔE was positive in all groups. The highest amount was in the 445nm 1.5w group and the lowest was seen in the control group and then in the 970nm 2w group (P<0.05). The highest dispersion of color change is related to the 445nm 1.5w group (P<0.05). In general, the results showed that the use of 445nm diode laser 1.5w (ΔE=12) and 970nm diode laser 2w (ΔE=37.5) was the most and least effective in teeth bleaching, respectively. According to the results of the present Invitro study, the 445 nm laser with a power of 1.5 watts had the most effect in changing tooth color, and the 970 nm group with a power of 2 watts showed the least effect. ","PeriodicalId":507900,"journal":{"name":"Laser Therapy","volume":"18 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141347591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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