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Journal of Affective Disorders最新文献

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Sex differences in effectiveness and adverse effects of mood stabilizers and antipsychotics: A systematic review 情绪稳定剂和抗精神病药物在疗效和不良反应方面的性别差异:系统综述
Pub Date : 2024-02-01 DOI: 10.1016/j.jad.2024.02.038
M. Ercis, Jorge A. Sánchez-Ruiz, L. Webb, Melissa Solares-Bravo, Hannah K. Betcher, Katherine M. Moore, Mark A. Frye, M. Veldic, Aysegul Ozerdem
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引用次数: 0
A longitudinal study of factors associated with cognitive frailty in middle-aged and elderly population based on the health ecology model 基于健康生态模型的中老年人群认知虚弱相关因素纵向研究
Pub Date : 2024-02-01 DOI: 10.1016/j.jad.2024.02.014
Ding-chun Hou, Yu-mei Sun, Zhi-ke Liu, Hong-yu Sun, Yi Li, Rui Wang
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引用次数: 0
Association between thiamine intake and depression: A national cross-sectional study 硫胺素摄入量与抑郁症之间的关系:一项全国横断面研究
Pub Date : 2024-02-01 DOI: 10.1016/j.jad.2024.02.053
Xiying Xu, Chao Qi, Shuang Xu, Xinhao Fu, Zhiyuan Li, Hong Ren, Qian Qian, Shanshan Guo
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引用次数: 0
Associations between sleep-behavioral traits and healthspan: A one-sample Mendelian randomization study based on 388,909 participants of the UK-Biobank 睡眠行为特征与健康寿命之间的关系:基于英国生物库 388 909 名参与者的单样本孟德尔随机研究
Pub Date : 2024-01-01 DOI: 10.1016/j.jad.2024.01.122
Muhammed Lamin Sambou, Xiaoyu Zhao, Tongtong Hong, Nanxi Wang, Juncheng Dai
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引用次数: 0
The Koukopoulos mixed depression rating scale (KMDRS) and the assessment of mixed symptoms during the perinatal period. Koukopoulos混合抑郁评定量表(KMDRS)与围产期混合症状评估。
IF 6.6 Pub Date : 2021-02-15 Epub Date: 2020-09-01 DOI: 10.1016/j.jad.2020.08.080
Alexia E Koukopoulos, Lavinia De Chiara, Alessio Simonetti, Georgios D Kotzalidis, Delfina Janiri, Giovanni Manfredi, Gloria Angeletti, Gabriele Sani

Background: Mixed symptoms in depression may underlie bipolar diathesis rather than unipolarity. Uncovering mixed depression (MxD) is crucial for appropriate management, especially in the perinatal period, as it may affect treatment planning and impact future child development. We used a scale specific for identifying MxD and tested its validity in pregnant and postpartum women with depression.

Methods: Women developing a major depressive episode (MDE) during their perinatal period extending from pregnancy to one year postpartum from November-2012 through June-2019 were assessed with BPRS-18, EPDS, CGI-S, GAF, HAM-A, HAM-D, Koukopoulos' Mixed Depression Rating Scale (KMDRS), TEMPS, and YMRS. They were classified, based on KMDRS criteria, as with mixed (MxD) or without (nonMxD) mixed symptoms. We conducted ROC analysis and performed factor analysis of the KMDRS.

Results: Of 45 included, MxD (N = 19) were biased towards diagnosis of bipolar disorder and nonMxD (N = 26) towards major depressive disorder. Other sociodemographic variables did not differ significantly between MxD and nonMxD. MxD scored higher on total YMRS, BPRS, and KMDRS, and on KMDRS-6 Subjective Feelings of Irritability and KMDRS-12 Suicidal Impulsiveness items. The KMDRS correlated in the entire sample, in MxD and nonMxD, with the YMRS and the BPRS, while correlating with the HAM-D in nonMxD only. The KMDRS showed acceptable AUC distribution, with a 68% sensitivity and 58% specificity. Best-fit was three-factor-structure, explaining 54.66% of cumulative variance.

Limitations: Small sample and cross-sectional design.

Conclusions: The KMDRS is fit for investigating MxD along with the YMRS and the BPRS in perinatal women with a MDE.

背景:抑郁症的混合症状可能是双相素质的基础,而不是单极性。发现混合性抑郁症(MxD)对于适当的管理至关重要,特别是在围产期,因为它可能影响治疗计划并影响未来的儿童发育。我们使用了一种专门用于识别MxD的量表,并测试了其在孕妇和产后抑郁症患者中的有效性。方法:采用BPRS-18、EPDS、CGI-S、GAF、HAM-A、HAM-D、Koukopoulos混合抑郁评定量表(KMDRS)、TEMPS和YMRS对2012年11月至2019年6月妊娠至产后1年围产期发生重度抑郁发作(MDE)的女性进行评估。根据KMDRS标准,将患者分为混合性(MxD)或无混合性(非MxD)症状。我们对KMDRS进行ROC分析和因子分析。结果:在纳入的45例患者中,MxD (N = 19)倾向于双相情感障碍的诊断,非MxD (N = 26)倾向于重度抑郁症的诊断。其他社会人口学变量在MxD和非MxD之间没有显著差异。MxD在YMRS、BPRS和KMDRS的总得分较高,在KMDRS-6主观易怒感和KMDRS-12自杀冲动项目得分较高。在整个样本中,在MxD和非MxD中,KMDRS与ymr和BPRS相关,而仅在非MxD中与HAM-D相关。KMDRS显示了可接受的AUC分布,具有68%的敏感性和58%的特异性。最适合的是三因素结构,解释54.66%的累积方差。局限性:小样本和横断面设计。结论:KMDRS适用于MDE围产儿MxD、YMRS和BPRS的调查。
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引用次数: 4
期刊
Journal of Affective Disorders
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