Pub Date : 2024-07-12DOI: 10.36348/sijog.2024.v07i07.002
Jafrin Yasmin Choudhury, Dr. Nahid Elora, Dr. Habiba Akther, Dr. Jakia Jahan Chowdhury, Dr. Umme Sayeeda Bilkish, Dr. Mustofa Khalid Ahmed Jaigyrder
Background: PCOS is the most common endocrine disorder in women that can lead to a variety of ailments associated with chronic anovulation and hyperandrogenism, it is also still a common cause of infertility in women. It is the most frequent endocrine and metabolic disorder among reproductive-aged women. PCOS (polycystic ovarian syndrome) is the most frequent cause of anovulatory infertility, accounting for more than 75% of all cases. This widespread problem affects around one in every six marriages and has a variety of causes across countries and social groups. Aims and Objective: The objective of this study was to evaluate the treatment strategies for infertile patients with diagnosed Polycystic Ovary Syndrome (PCOS). Material and Methods: This study looked at 80 cases of infertility caused by polycystic ovarian syndrome. From August 2021 to July 2022, this study evaluated 80 cases of infertility with PCOS at a tertiary medical college. The diagnosis was made using a hormone assay, ultrasound, and laparoscopy. Treatment options included clomiphene citrate, letrozole, and laparoscopic ovarian drilling. Results: In our study, the majority (50%) were between the ages of 26 and 30 years old, and 100% of patients complained of infertility, with 66.25% being of the primary type. Menstrual abnormalities affected 73.75% of women. The LH: FSH ratio was greater than 1.6 in approximately 85% of responders, and 77.5% of women had enlarged polycystic ovaries. Clomiphene citrate had a conception rate of 24%, Letrozole 31% had a rate of 20%, and laparoscopic ovarian drilling followed by Letrozole had a rate of 60%. Conclusion: Polycystic ovarian syndrome is a complex illness that necessitates a variety of treatment techniques based on the reason a patient seeks treatment. Aside from diet and fitness improvements, most patients with good conception rates require lifestyle modification treatment such as C/C and laparoscopic ovarian drilling.
{"title":"Evaluation and Treatment Strategies for Infertile Patients with Diagnosed Polycystic Ovary Syndrome (PCOS)","authors":"Jafrin Yasmin Choudhury, Dr. Nahid Elora, Dr. Habiba Akther, Dr. Jakia Jahan Chowdhury, Dr. Umme Sayeeda Bilkish, Dr. Mustofa Khalid Ahmed Jaigyrder","doi":"10.36348/sijog.2024.v07i07.002","DOIUrl":"https://doi.org/10.36348/sijog.2024.v07i07.002","url":null,"abstract":"Background: PCOS is the most common endocrine disorder in women that can lead to a variety of ailments associated with chronic anovulation and hyperandrogenism, it is also still a common cause of infertility in women. It is the most frequent endocrine and metabolic disorder among reproductive-aged women. PCOS (polycystic ovarian syndrome) is the most frequent cause of anovulatory infertility, accounting for more than 75% of all cases. This widespread problem affects around one in every six marriages and has a variety of causes across countries and social groups. Aims and Objective: The objective of this study was to evaluate the treatment strategies for infertile patients with diagnosed Polycystic Ovary Syndrome (PCOS). Material and Methods: This study looked at 80 cases of infertility caused by polycystic ovarian syndrome. From August 2021 to July 2022, this study evaluated 80 cases of infertility with PCOS at a tertiary medical college. The diagnosis was made using a hormone assay, ultrasound, and laparoscopy. Treatment options included clomiphene citrate, letrozole, and laparoscopic ovarian drilling. Results: In our study, the majority (50%) were between the ages of 26 and 30 years old, and 100% of patients complained of infertility, with 66.25% being of the primary type. Menstrual abnormalities affected 73.75% of women. The LH: FSH ratio was greater than 1.6 in approximately 85% of responders, and 77.5% of women had enlarged polycystic ovaries. Clomiphene citrate had a conception rate of 24%, Letrozole 31% had a rate of 20%, and laparoscopic ovarian drilling followed by Letrozole had a rate of 60%. Conclusion: Polycystic ovarian syndrome is a complex illness that necessitates a variety of treatment techniques based on the reason a patient seeks treatment. Aside from diet and fitness improvements, most patients with good conception rates require lifestyle modification treatment such as C/C and laparoscopic ovarian drilling.","PeriodicalId":509673,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141652869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-08DOI: 10.36348/sijog.2024.v07i07.001
Dr Pragya Isser, Dr Sai Borawake
Background: HELLP syndrome, a severe pregnancy complication characterized by hemolysis, elevated liver enzymes, and low platelet count, occurs in 0.5 to 0.9% of all pregnancies and in 10–20% of severe preeclampsia cases. It poses significant risks to both mother and fetus, presenting diagnostic and therapeutic challenges. Patients often experience epigastric or right upper quadrant pain, hypertension, proteinuria, fatigue, nausea, vomiting, sudden weight gain, and headaches. HELLP syndrome typically occurs in the second and third trimesters (27-37 weeks) and 15–30% of cases present postpartum. The exact causes remain unclear but may involve placental origins, autoimmune factors, gene mutations, or fatty acid oxidation disorders. Aims and Objectives: To analyze the clinical profile of HELLP syndrome cases and to assess maternal and perinatal outcomes, including morbidity and mortality. Material and Methods: This prospective cross-sectional study was conducted in the Obstetrics and Gynecology department at Pravara Rural Hospital, Loni, involving 45 patients with severe preeclampsia and eclampsia above 28 weeks of gestation diagnosed with HELLP syndrome. Patients were admitted to the ICU, and detailed histories and examinations were recorded. Patients were divided into two groups: those with HELLP syndrome (Group A) and those without (Group B). Results: Group A had a higher representation in the 20-22 age bracket, while Group B had more members aged 22-24. Cesarean sections were more common in Group A, whereas vaginal deliveries were more frequent in Group B. Blood pressure readings were higher in Group A. Maternal complications, such as abruption placentae, DIC, hepatic infarction, acute renal failure, and ascites, were more frequent in Group A, as were neonatal complications like IUGR, preterm delivery, neonatal thrombocytopenia, and RDS. Conclusion: The study reveals significant differences between patients with and without HELLP syndrome. Group A included younger patients, more first-time mothers, and a higher incidence of complications and mortality. These findings highlight the need for tailored management strategies for severe preeclampsia/eclampsia, especially in those with HELLP syndrome, to improve maternal and neonatal outcomes.
{"title":"Clinical Study of HELLP Syndrome and It's Outcome at Pravara Rural Hospital, Loni","authors":"Dr Pragya Isser, Dr Sai Borawake","doi":"10.36348/sijog.2024.v07i07.001","DOIUrl":"https://doi.org/10.36348/sijog.2024.v07i07.001","url":null,"abstract":"Background: HELLP syndrome, a severe pregnancy complication characterized by hemolysis, elevated liver enzymes, and low platelet count, occurs in 0.5 to 0.9% of all pregnancies and in 10–20% of severe preeclampsia cases. It poses significant risks to both mother and fetus, presenting diagnostic and therapeutic challenges. Patients often experience epigastric or right upper quadrant pain, hypertension, proteinuria, fatigue, nausea, vomiting, sudden weight gain, and headaches. HELLP syndrome typically occurs in the second and third trimesters (27-37 weeks) and 15–30% of cases present postpartum. The exact causes remain unclear but may involve placental origins, autoimmune factors, gene mutations, or fatty acid oxidation disorders. Aims and Objectives: To analyze the clinical profile of HELLP syndrome cases and to assess maternal and perinatal outcomes, including morbidity and mortality. Material and Methods: This prospective cross-sectional study was conducted in the Obstetrics and Gynecology department at Pravara Rural Hospital, Loni, involving 45 patients with severe preeclampsia and eclampsia above 28 weeks of gestation diagnosed with HELLP syndrome. Patients were admitted to the ICU, and detailed histories and examinations were recorded. Patients were divided into two groups: those with HELLP syndrome (Group A) and those without (Group B). Results: Group A had a higher representation in the 20-22 age bracket, while Group B had more members aged 22-24. Cesarean sections were more common in Group A, whereas vaginal deliveries were more frequent in Group B. Blood pressure readings were higher in Group A. Maternal complications, such as abruption placentae, DIC, hepatic infarction, acute renal failure, and ascites, were more frequent in Group A, as were neonatal complications like IUGR, preterm delivery, neonatal thrombocytopenia, and RDS. Conclusion: The study reveals significant differences between patients with and without HELLP syndrome. Group A included younger patients, more first-time mothers, and a higher incidence of complications and mortality. These findings highlight the need for tailored management strategies for severe preeclampsia/eclampsia, especially in those with HELLP syndrome, to improve maternal and neonatal outcomes.","PeriodicalId":509673,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141670091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Triple-negative breast cancer (estrogen receptor negative, progesterone receptor negative and HER2 negative) is a particularly high-risk breast cancer which does not receive specific therapy targeting these proteins. We report the case of a 23-year-old patient diagnosed with triple-negative breast cancer of the left breast with a family history of breast cancer and carrying a BRCA1 mutation. The classification of breast cancer based on genomic data is required to allow us to optimize therapies and improve the management of breast cancer patients.
{"title":"Triple-Negative Breast Cancer in a Young 23-Year-Old Woman with BRCA Mutation A about A Case and Literature Review","authors":"Ismail Belhaouz, Moad Belouad, Liban Mahdi, Samir Bargach","doi":"10.36348/sijog.2024.v07i05.001","DOIUrl":"https://doi.org/10.36348/sijog.2024.v07i05.001","url":null,"abstract":"Triple-negative breast cancer (estrogen receptor negative, progesterone receptor negative and HER2 negative) is a particularly high-risk breast cancer which does not receive specific therapy targeting these proteins. We report the case of a 23-year-old patient diagnosed with triple-negative breast cancer of the left breast with a family history of breast cancer and carrying a BRCA1 mutation. The classification of breast cancer based on genomic data is required to allow us to optimize therapies and improve the management of breast cancer patients.","PeriodicalId":509673,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141015165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-14DOI: 10.36348/sijog.2024.v07i02.002
Sidibe, S, D. S, D. I, M. K, K. S, D. A, Diallo, M, Diarra, K. K, icko, O. A. A
Unassisted home birth exposes mother and child to the most harmful complications. These complications are identified as one of the main causes of maternal and neonatal morbidity and mortality. Goal: To study the factors favoring home births in the Monisso health area. Method: Descriptive cross-sectional study in the period from January 1 to December 31, 2020 in the Monisso health area. Results: The proportion of home births was 80% (N= 210). The reasons given were respectively: the brevity of the labor of delivery (31.55%), the lack of financial means (25.60%), socio-cultural reasons (23.21%), the long distance between the village and the CSCOM (12 .5%), the high cost of delivery costs in the health center (6.55%). Conclusion: Home births are still very common in rural areas, particularly in developing countries.
{"title":"Home Delivery in the Monisso Health Area: Tominian Health District","authors":"Sidibe, S, D. S, D. I, M. K, K. S, D. A, Diallo, M, Diarra, K. K, icko, O. A. A","doi":"10.36348/sijog.2024.v07i02.002","DOIUrl":"https://doi.org/10.36348/sijog.2024.v07i02.002","url":null,"abstract":"Unassisted home birth exposes mother and child to the most harmful complications. These complications are identified as one of the main causes of maternal and neonatal morbidity and mortality. Goal: To study the factors favoring home births in the Monisso health area. Method: Descriptive cross-sectional study in the period from January 1 to December 31, 2020 in the Monisso health area. Results: The proportion of home births was 80% (N= 210). The reasons given were respectively: the brevity of the labor of delivery (31.55%), the lack of financial means (25.60%), socio-cultural reasons (23.21%), the long distance between the village and the CSCOM (12 .5%), the high cost of delivery costs in the health center (6.55%). Conclusion: Home births are still very common in rural areas, particularly in developing countries.","PeriodicalId":509673,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139838103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-14DOI: 10.36348/sijog.2024.v07i02.002
Sidibe, S, D. S, D. I, M. K, K. S, D. A, Diallo, M, Diarra, K. K, icko, O. A. A
Unassisted home birth exposes mother and child to the most harmful complications. These complications are identified as one of the main causes of maternal and neonatal morbidity and mortality. Goal: To study the factors favoring home births in the Monisso health area. Method: Descriptive cross-sectional study in the period from January 1 to December 31, 2020 in the Monisso health area. Results: The proportion of home births was 80% (N= 210). The reasons given were respectively: the brevity of the labor of delivery (31.55%), the lack of financial means (25.60%), socio-cultural reasons (23.21%), the long distance between the village and the CSCOM (12 .5%), the high cost of delivery costs in the health center (6.55%). Conclusion: Home births are still very common in rural areas, particularly in developing countries.
{"title":"Home Delivery in the Monisso Health Area: Tominian Health District","authors":"Sidibe, S, D. S, D. I, M. K, K. S, D. A, Diallo, M, Diarra, K. K, icko, O. A. A","doi":"10.36348/sijog.2024.v07i02.002","DOIUrl":"https://doi.org/10.36348/sijog.2024.v07i02.002","url":null,"abstract":"Unassisted home birth exposes mother and child to the most harmful complications. These complications are identified as one of the main causes of maternal and neonatal morbidity and mortality. Goal: To study the factors favoring home births in the Monisso health area. Method: Descriptive cross-sectional study in the period from January 1 to December 31, 2020 in the Monisso health area. Results: The proportion of home births was 80% (N= 210). The reasons given were respectively: the brevity of the labor of delivery (31.55%), the lack of financial means (25.60%), socio-cultural reasons (23.21%), the long distance between the village and the CSCOM (12 .5%), the high cost of delivery costs in the health center (6.55%). Conclusion: Home births are still very common in rural areas, particularly in developing countries.","PeriodicalId":509673,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139778518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-12DOI: 10.36348/sijog.2024.v07i02.001
S. Rajia, Sufia Khatun, Mohammad Maksudur Rahman, Samina Sultana
Introduction: Cervical cancer, a significant public health issue, necessitates reliable diagnostic strategies for early detection and management. In the pursuit of effective cervical cancer screening strategies, the integration of colposcopy and HPV-DNA testing is critical, especially in high-risk populations. The study evaluates the diagnostic efficacy of these methods in patients presenting with symptoms indicative of potential cervical malignancy. Methods: This prospective observational study was conducted at the Department of Obstetrics and Gynecology, President Abdul Hamid Medical College and Hospital, Kishoreganj, Bangladesh. The study included a total of 82 participants collected over a 1-year period from July 2022 to June 2023 following the inclusion and exclusion criteria. Patients with VIA Positive diagnosis, abnormal pap-smear results, contact or abnormal per-vaginal bleeding, foul-smelling per-vaginal discharge, and an unhealthy cervix were included in the study, while currently pregnant women, nulliparous, and postmenopausal women, patients with cervical or vaginal growths, and non-cooperative patients were excluded from the study. Result: The mean age of participants was 36.51 years, with most marriages occurring at an average age of 17.07 years. The study identified a high prevalence of multipara status (50.0% had 2-3 children, 36.6% had more than 3). The majority of first deliveries occurred between ages 16 and 22. A significant correlation was found between age and parity (r = .502, p < .01), and a strong association between age of marriage and age at first delivery (r = .815, p < .01). HPV-DNA positivity was 7.3%, while abnormal colposcopy findings (CIN I-III) were observed in 40.7% of cases. Negative correlations were observed between age of marriage and colposcopy findings (r = -.308, p < .01). Conclusion: This study underscores the importance of age, marital history, and parity in the context of cervical cancer screening. The low HPV-DNA positivity rate compared to the higher incidence of abnormal colposcopy findings suggests the need for a combined diagnostic approach. The findings advocate for tailored cervical cancer screening strategies that integrate both colposcopy and HPV-DNA testing, especially in resource-limited settings.
{"title":"Evaluation of Cervical Cancer by Colposcopy and HPV-DNA in President Abdul Hamid Medical College, Kishoreganj","authors":"S. Rajia, Sufia Khatun, Mohammad Maksudur Rahman, Samina Sultana","doi":"10.36348/sijog.2024.v07i02.001","DOIUrl":"https://doi.org/10.36348/sijog.2024.v07i02.001","url":null,"abstract":"Introduction: Cervical cancer, a significant public health issue, necessitates reliable diagnostic strategies for early detection and management. In the pursuit of effective cervical cancer screening strategies, the integration of colposcopy and HPV-DNA testing is critical, especially in high-risk populations. The study evaluates the diagnostic efficacy of these methods in patients presenting with symptoms indicative of potential cervical malignancy. Methods: This prospective observational study was conducted at the Department of Obstetrics and Gynecology, President Abdul Hamid Medical College and Hospital, Kishoreganj, Bangladesh. The study included a total of 82 participants collected over a 1-year period from July 2022 to June 2023 following the inclusion and exclusion criteria. Patients with VIA Positive diagnosis, abnormal pap-smear results, contact or abnormal per-vaginal bleeding, foul-smelling per-vaginal discharge, and an unhealthy cervix were included in the study, while currently pregnant women, nulliparous, and postmenopausal women, patients with cervical or vaginal growths, and non-cooperative patients were excluded from the study. Result: The mean age of participants was 36.51 years, with most marriages occurring at an average age of 17.07 years. The study identified a high prevalence of multipara status (50.0% had 2-3 children, 36.6% had more than 3). The majority of first deliveries occurred between ages 16 and 22. A significant correlation was found between age and parity (r = .502, p < .01), and a strong association between age of marriage and age at first delivery (r = .815, p < .01). HPV-DNA positivity was 7.3%, while abnormal colposcopy findings (CIN I-III) were observed in 40.7% of cases. Negative correlations were observed between age of marriage and colposcopy findings (r = -.308, p < .01). Conclusion: This study underscores the importance of age, marital history, and parity in the context of cervical cancer screening. The low HPV-DNA positivity rate compared to the higher incidence of abnormal colposcopy findings suggests the need for a combined diagnostic approach. The findings advocate for tailored cervical cancer screening strategies that integrate both colposcopy and HPV-DNA testing, especially in resource-limited settings.","PeriodicalId":509673,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139784949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-12DOI: 10.36348/sijog.2024.v07i02.001
S. Rajia, Sufia Khatun, Mohammad Maksudur Rahman, Samina Sultana
Introduction: Cervical cancer, a significant public health issue, necessitates reliable diagnostic strategies for early detection and management. In the pursuit of effective cervical cancer screening strategies, the integration of colposcopy and HPV-DNA testing is critical, especially in high-risk populations. The study evaluates the diagnostic efficacy of these methods in patients presenting with symptoms indicative of potential cervical malignancy. Methods: This prospective observational study was conducted at the Department of Obstetrics and Gynecology, President Abdul Hamid Medical College and Hospital, Kishoreganj, Bangladesh. The study included a total of 82 participants collected over a 1-year period from July 2022 to June 2023 following the inclusion and exclusion criteria. Patients with VIA Positive diagnosis, abnormal pap-smear results, contact or abnormal per-vaginal bleeding, foul-smelling per-vaginal discharge, and an unhealthy cervix were included in the study, while currently pregnant women, nulliparous, and postmenopausal women, patients with cervical or vaginal growths, and non-cooperative patients were excluded from the study. Result: The mean age of participants was 36.51 years, with most marriages occurring at an average age of 17.07 years. The study identified a high prevalence of multipara status (50.0% had 2-3 children, 36.6% had more than 3). The majority of first deliveries occurred between ages 16 and 22. A significant correlation was found between age and parity (r = .502, p < .01), and a strong association between age of marriage and age at first delivery (r = .815, p < .01). HPV-DNA positivity was 7.3%, while abnormal colposcopy findings (CIN I-III) were observed in 40.7% of cases. Negative correlations were observed between age of marriage and colposcopy findings (r = -.308, p < .01). Conclusion: This study underscores the importance of age, marital history, and parity in the context of cervical cancer screening. The low HPV-DNA positivity rate compared to the higher incidence of abnormal colposcopy findings suggests the need for a combined diagnostic approach. The findings advocate for tailored cervical cancer screening strategies that integrate both colposcopy and HPV-DNA testing, especially in resource-limited settings.
{"title":"Evaluation of Cervical Cancer by Colposcopy and HPV-DNA in President Abdul Hamid Medical College, Kishoreganj","authors":"S. Rajia, Sufia Khatun, Mohammad Maksudur Rahman, Samina Sultana","doi":"10.36348/sijog.2024.v07i02.001","DOIUrl":"https://doi.org/10.36348/sijog.2024.v07i02.001","url":null,"abstract":"Introduction: Cervical cancer, a significant public health issue, necessitates reliable diagnostic strategies for early detection and management. In the pursuit of effective cervical cancer screening strategies, the integration of colposcopy and HPV-DNA testing is critical, especially in high-risk populations. The study evaluates the diagnostic efficacy of these methods in patients presenting with symptoms indicative of potential cervical malignancy. Methods: This prospective observational study was conducted at the Department of Obstetrics and Gynecology, President Abdul Hamid Medical College and Hospital, Kishoreganj, Bangladesh. The study included a total of 82 participants collected over a 1-year period from July 2022 to June 2023 following the inclusion and exclusion criteria. Patients with VIA Positive diagnosis, abnormal pap-smear results, contact or abnormal per-vaginal bleeding, foul-smelling per-vaginal discharge, and an unhealthy cervix were included in the study, while currently pregnant women, nulliparous, and postmenopausal women, patients with cervical or vaginal growths, and non-cooperative patients were excluded from the study. Result: The mean age of participants was 36.51 years, with most marriages occurring at an average age of 17.07 years. The study identified a high prevalence of multipara status (50.0% had 2-3 children, 36.6% had more than 3). The majority of first deliveries occurred between ages 16 and 22. A significant correlation was found between age and parity (r = .502, p < .01), and a strong association between age of marriage and age at first delivery (r = .815, p < .01). HPV-DNA positivity was 7.3%, while abnormal colposcopy findings (CIN I-III) were observed in 40.7% of cases. Negative correlations were observed between age of marriage and colposcopy findings (r = -.308, p < .01). Conclusion: This study underscores the importance of age, marital history, and parity in the context of cervical cancer screening. The low HPV-DNA positivity rate compared to the higher incidence of abnormal colposcopy findings suggests the need for a combined diagnostic approach. The findings advocate for tailored cervical cancer screening strategies that integrate both colposcopy and HPV-DNA testing, especially in resource-limited settings.","PeriodicalId":509673,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139844600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-06DOI: 10.36348/sijog.2024.v07i01.001
Ara I, Sultana F, Najnin R, Afreen S, Tuhin Tb
Objective: This is a cross-sectional study done to identify epidemiological perspectives, etiological factors, and clinical presentations of uterine fibroids. Methods: The study subjects were 50 patients diagnosed as a case of fibroid uterus, and admitted Department of Gynaecology and Obstetrics, Rangpur Medical College and Hospital from March 2011 to March 2012. A pre-selected data sheet was formed to collect relevant information about the women. All the information regarding age, parity, socioeconomic status, detailed menstrual history, obstetrics history, clinical exam, per speculum exam, and pelvic exam & investigations were done according to pre-selected data. Result: Total study population was 50 among them greater frequency was found in the fourth (60%) decades of life and the majority of them (56%) were of middle-class families 92% where 50% were Illiterate. Most (48%) of the patients were in para 3-5 and 72% of patients used contraception. We found that the majority (80%) of patients presented with menstrual abnormalities and out of 50 patients 41 patients had palpable uterus. Maximum (36%) patients suffered from obesity and 96% of patients had a haemoglobin percentage less than 60%. 98% of patients had conclusive USG findings in their clinical diagnosis. Conclusion: The majority of these patients were between 31 to 40 years of age. The common mode of presentation was menstrual disturbances 80% such as menorrhagia and dysmenorrhea. Diagnosis was based on clinical exam and some patients required USG.
{"title":"Evaluating the Epidemiological Insights, Etiology, and Clinical Manifestations, of Uterine Fibroids","authors":"Ara I, Sultana F, Najnin R, Afreen S, Tuhin Tb","doi":"10.36348/sijog.2024.v07i01.001","DOIUrl":"https://doi.org/10.36348/sijog.2024.v07i01.001","url":null,"abstract":"Objective: This is a cross-sectional study done to identify epidemiological perspectives, etiological factors, and clinical presentations of uterine fibroids. Methods: The study subjects were 50 patients diagnosed as a case of fibroid uterus, and admitted Department of Gynaecology and Obstetrics, Rangpur Medical College and Hospital from March 2011 to March 2012. A pre-selected data sheet was formed to collect relevant information about the women. All the information regarding age, parity, socioeconomic status, detailed menstrual history, obstetrics history, clinical exam, per speculum exam, and pelvic exam & investigations were done according to pre-selected data. Result: Total study population was 50 among them greater frequency was found in the fourth (60%) decades of life and the majority of them (56%) were of middle-class families 92% where 50% were Illiterate. Most (48%) of the patients were in para 3-5 and 72% of patients used contraception. We found that the majority (80%) of patients presented with menstrual abnormalities and out of 50 patients 41 patients had palpable uterus. Maximum (36%) patients suffered from obesity and 96% of patients had a haemoglobin percentage less than 60%. 98% of patients had conclusive USG findings in their clinical diagnosis. Conclusion: The majority of these patients were between 31 to 40 years of age. The common mode of presentation was menstrual disturbances 80% such as menorrhagia and dysmenorrhea. Diagnosis was based on clinical exam and some patients required USG.","PeriodicalId":509673,"journal":{"name":"Scholars International Journal of Obstetrics and Gynecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139535806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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