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Natural flavonoids-derived enzyme mimics DHKNase balance the two-edged ROS function for wound healing and inflammatory bowel disease therapy 天然类黄酮衍生酶模拟 DHKNase 可平衡 ROS 的双刃功能，促进伤口愈合和炎症性肠病治疗
IF 8.5 Q1 MULTIDISCIPLINARY SCIENCES
Research
Pub Date : 2024-08-08 DOI: 10.34133/research.0464
Guangfu Feng, Huaizu Zhang, Huipeng Liu, Xiaoyan Zhang, Hongmei Jiang, Sijie Liao, Xingyu Luo, Hao Yao, Bo Xiang, Shiyu Liu, Jiali Zhang, Jiaheng Zhang, Jun-Feng Fang
{"title":"Natural flavonoids-derived enzyme mimics DHKNase balance the two-edged ROS function for wound healing and inflammatory bowel disease therapy","authors":"Guangfu Feng, Huaizu Zhang, Huipeng Liu, Xiaoyan Zhang, Hongmei Jiang, Sijie Liao, Xingyu Luo, Hao Yao, Bo Xiang, Shiyu Liu, Jiali Zhang, Jiaheng Zhang, Jun-Feng Fang","doi":"10.34133/research.0464","DOIUrl":"https://doi.org/10.34133/research.0464","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":8.5,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141928879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Melatonergic signaling sustains food allergy through FcεRI recycling 褪黑激素能信号通过 FcεRI 再循环维持食物过敏反应
Research
Pub Date : 2024-06-11 DOI: 10.34133/research.0418
Youxia Wang, Xinmei Zhang, Ifen Huang, Chunxue Liu, wenkai Ren, Liangpeng Ge, Hao Wang
{"title":"Melatonergic signaling sustains food allergy through FcεRI recycling","authors":"Youxia Wang, Xinmei Zhang, Ifen Huang, Chunxue Liu, wenkai Ren, Liangpeng Ge, Hao Wang","doi":"10.34133/research.0418","DOIUrl":"https://doi.org/10.34133/research.0418","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141360061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategies for small extracellular vesicle-based cancer immunotherapy 基于细胞外小泡的癌症免疫疗法策略
Research
Pub Date : 2024-06-11 DOI: 10.34133/research.0421
Yundi Chen, Shasha Tang, Fengfeng Cai, Yuan Wan
{"title":"Strategies for small extracellular vesicle-based cancer immunotherapy","authors":"Yundi Chen, Shasha Tang, Fengfeng Cai, Yuan Wan","doi":"10.34133/research.0421","DOIUrl":"https://doi.org/10.34133/research.0421","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141355389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eclipsing Toxicity, Enhancing Efficacy: Clofazimine's Vanguard in the Realm of anti-PD-1 and CTLA-4 Immunotherapy 消除毒性，提高疗效：氯法齐明在抗PD-1和CTLA-4免疫疗法领域的先锋作用
Research
Pub Date : 2024-06-11 DOI: 10.34133/research.0419
Ruirong Tan, Junning Zhao, Q. Shubhra
{"title":"Eclipsing Toxicity, Enhancing Efficacy: Clofazimine's Vanguard in the Realm of anti-PD-1 and CTLA-4 Immunotherapy","authors":"Ruirong Tan, Junning Zhao, Q. Shubhra","doi":"10.34133/research.0419","DOIUrl":"https://doi.org/10.34133/research.0419","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141355893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traditional Chinese medicine integrated multifunctional responsive core-shell microneedles for dermatosis treatment 用于治疗皮肤病的中药集成多功能响应核壳微针
Research
Pub Date : 2024-06-11 DOI: 10.34133/research.0420
Xi Luan, Xiaoxuan Zhang, Qichen Luan, Jingjing Gan, Yu Wang, Yuanjin Zhao
{"title":"Traditional Chinese medicine integrated multifunctional responsive core-shell microneedles for dermatosis treatment","authors":"Xi Luan, Xiaoxuan Zhang, Qichen Luan, Jingjing Gan, Yu Wang, Yuanjin Zhao","doi":"10.34133/research.0420","DOIUrl":"https://doi.org/10.34133/research.0420","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141356121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unconscious Gaze-Triggered Attentional Orienting: Distinguishing Innate and Acquired Components of Social Attention in Children and Adults with Autistic Traits and Autism Spectrum Disorders 无意识凝视触发的注意定向：区分自闭症特质和自闭症谱系障碍儿童和成人社交注意力的先天和后天因素
Research
Pub Date : 2024-06-06 DOI: 10.34133/research.0417
Fang Yang, Junbin Tian, Peijun Yuan, Chunyan Liu, Xinyuan Zhang, Li Yang, Yi Jiang
{"title":"Unconscious Gaze-Triggered Attentional Orienting: Distinguishing Innate and Acquired Components of Social Attention in Children and Adults with Autistic Traits and Autism Spectrum Disorders","authors":"Fang Yang, Junbin Tian, Peijun Yuan, Chunyan Liu, Xinyuan Zhang, Li Yang, Yi Jiang","doi":"10.34133/research.0417","DOIUrl":"https://doi.org/10.34133/research.0417","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141377780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gut Microbiota Improves Prognostic Prediction in Critically Ill COVID-19 Patients alongside Immunological and Hematological indicators 肠道微生物群与免疫学和血液学指标一起提高了 COVID-19 重症患者的预后预测能力
Research
Pub Date : 2024-04-25 DOI: 10.34133/research.0389
Jiaxin Zhong, Li Guo, Yeming Wang, Xuan Jiang, Chun Wang, Yan Xiao, Ying Wang, Fei Zhou, Chao Wu, Lan Chen, Xinming Wang, Jianwei Wang, Bin Cao, Mingkun Li, Lili Ren
{"title":"Gut Microbiota Improves Prognostic Prediction in Critically Ill COVID-19 Patients alongside Immunological and Hematological indicators","authors":"Jiaxin Zhong, Li Guo, Yeming Wang, Xuan Jiang, Chun Wang, Yan Xiao, Ying Wang, Fei Zhou, Chao Wu, Lan Chen, Xinming Wang, Jianwei Wang, Bin Cao, Mingkun Li, Lili Ren","doi":"10.34133/research.0389","DOIUrl":"https://doi.org/10.34133/research.0389","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140658022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dissecting Spatiotemporal Structures in Spatial Transcriptomics via Diffusion-based Adversarial Learning 通过基于扩散的对抗学习剖析空间转录组学中的时空结构
Research
Pub Date : 2024-04-25 DOI: 10.34133/research.0390
Haiyun Wang, Jianping Zhao, Qing Nie, Chunhou Zheng, Xiaoqiang Sun
{"title":"Dissecting Spatiotemporal Structures in Spatial Transcriptomics via Diffusion-based Adversarial Learning","authors":"Haiyun Wang, Jianping Zhao, Qing Nie, Chunhou Zheng, Xiaoqiang Sun","doi":"10.34133/research.0390","DOIUrl":"https://doi.org/10.34133/research.0390","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140655307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-type stochastic resonances for noise-enhanced mechanical, optical, and acoustic sensing 用于噪声增强型机械、光学和声学传感的多类型随机共振
Research
Pub Date : 2024-04-23 DOI: 10.34133/research.0386
Zhu Liu, Kai Qu, Ke Chen, Zhipeng Li
{"title":"Multi-type stochastic resonances for noise-enhanced mechanical, optical, and acoustic sensing","authors":"Zhu Liu, Kai Qu, Ke Chen, Zhipeng Li","doi":"10.34133/research.0386","DOIUrl":"https://doi.org/10.34133/research.0386","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140671222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrating Single-cell and Spatial Transcriptomics to uncover and elucidate a GP73-mediated Pro-angiogenic Regulatory Networks in Hepatocellular Carcinoma 整合单细胞和空间转录组学发现并阐明肝细胞癌中 GP73 介导的促血管生成调控网络
Research
Pub Date : 2024-04-23 DOI: 10.34133/research.0387
Jiazhou Ye, Xing Gao, Xi Huang, Shilin Huang, Dandan Zeng, Wenfeng Luo, Can zeng, Cheng Lu, Lu Lu, Hongyang huang, Kaixiang mo, Julu Huang, Shizhou Li, Minchao Tang, Tianzhun wu, Rong-yun Mai, Min luo, Mingzhi xie, Shan Wang, Yongqiang Li, Yan Lin, R. Liang
{"title":"Integrating Single-cell and Spatial Transcriptomics to uncover and elucidate a GP73-mediated Pro-angiogenic Regulatory Networks in Hepatocellular Carcinoma","authors":"Jiazhou Ye, Xing Gao, Xi Huang, Shilin Huang, Dandan Zeng, Wenfeng Luo, Can zeng, Cheng Lu, Lu Lu, Hongyang huang, Kaixiang mo, Julu Huang, Shizhou Li, Minchao Tang, Tianzhun wu, Rong-yun Mai, Min luo, Mingzhi xie, Shan Wang, Yongqiang Li, Yan Lin, R. Liang","doi":"10.34133/research.0387","DOIUrl":"https://doi.org/10.34133/research.0387","url":null,"abstract":"","PeriodicalId":516495,"journal":{"name":"Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140670536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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