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Adrenal gland haemangioma, a rare entity difficult to differentiate from malignancy 肾上腺血管瘤,一种难以与恶性肿瘤区分的罕见实体
Pub Date : 2024-08-08 DOI: 10.1093/bjrcr/uaae027
Paola Lopez Gomez, Miguel Paniagua Gonzalez, Angela Garcia Perez, Luis Alberto Mullor Delgado
Adrenal haemangioma is a rare benign vascular lesion, which is usually asymptomatic and it is typically discovered incidentally on radiographic imaging. Differential diagnosis from other benign or malignant adrenal neoplasms may be challenging, and in many cases, the diagnosis is only possible after surgical resection. We present a case of a 39 year-old female with abdominal pain in the upper right quadrant, who was referred to our hospital after incidentally discovering a mass above the right kidney on abdominal ultrasonography. MRI revealed an adrenal mass, with features not indicative of adenoma and suggestive of adrenal haemangioma, without ruling out other possible diagnoses such us phaeochromocytoma and adrenal cortical carcinoma. Biochemical tests did not reveal any endocrine dysfunction. The patient underwent adrenalectomy, and histopathological analysis confirmed a venous haemangioma. Adrenal gland haemangioma is an unusual vascular lesion, typically diagnosed incidentally during abdominal imaging. Certain radiologic features may raise suspicion for malignancy, making it difficult to distinguish them from a primary adrenal cortical carcinoma. They may also grow large, compressing surrounding structures and causing abdominal pain, or may rupture, leading to retroperitoneal hemorrhage. For these reasons, some authors recommend excision of all suspected adrenal haemangiomas, and in many cases, the final diagnosis is made only after surgical removal.
肾上腺血管瘤是一种罕见的良性血管病变,通常没有症状,通常是在放射影像学检查中偶然发现的。与其他良性或恶性肾上腺肿瘤的鉴别诊断可能具有挑战性,在许多情况下,只有在手术切除后才能确诊。我们报告了一例 39 岁女性患者的病例,她右上腹疼痛,在腹部超声波检查中偶然发现右肾上方有肿块,于是转诊至我院。核磁共振检查发现肾上腺肿块,其特征并非腺瘤,而是肾上腺血管瘤,但未排除其他可能的诊断,如肾上腺绒毛膜细胞瘤和肾上腺皮质癌。生化检查未发现任何内分泌功能障碍。患者接受了肾上腺切除术,组织病理分析证实为静脉血管瘤。肾上腺血管瘤是一种不常见的血管病变,通常是在腹部造影时偶然诊断出来的。某些放射学特征可能会引起对恶性肿瘤的怀疑,因此很难将其与原发性肾上腺皮质癌区分开来。血管瘤还可能长得很大,压迫周围结构并引起腹痛,或者可能破裂,导致腹膜后出血。由于这些原因,一些作者建议切除所有疑似肾上腺血管瘤,在许多病例中,只有在手术切除后才能做出最终诊断。
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引用次数: 0
Lemierre’s syndrome presenting with arterial and Central nervous system involvement 表现为动脉和中枢神经系统受累的勒米埃尔综合征
Pub Date : 2024-08-08 DOI: 10.1093/bjrcr/uaae026
Brandon Simons, M. Williams, Laura Hayes, Kanika Gupta, Tushar Chandra
A 17-year-old male presented with acute onset right-sided facial swelling, trismus, pharyngitis, and sepsis. An initial CT abdomen and pelvis revealed multifocal bilateral nodular cavitary lung lesions. CT soft tissue neck with contrast demonstrated a parapharyngeal abscess and thrombophlebitis of the right internal jugular vein. The patient was subsequently diagnosed with Lemierre’s syndrome. On the following day, the patient’s neurological status markedly declined. Brain MRI/MRA/MRV showed right internal carotid artery narrowing, multiple areas of acute and subacute infarctions secondary to vasculitis, meningitis, venous sinus thrombosis, and intracerebral abscesses. Workup for primary causes of intracranial vasculitis were negative. Although commonly presented as venous disease, this case highlights a rare presentation of Lemierre’s syndrome with arterial involvement and significant intracranial complications. Clinicians should consider vasculitis and central nervous system involvement as potential complications of Lemierre’s syndrome rather than searching for separate etiologies.
一名 17 岁的男性因急性起病出现右侧面部肿胀、三叉神经痛、咽炎和败血症而就诊。腹部和骨盆 CT 显示双侧肺部多灶性结节性空洞病变。使用造影剂的颈部软组织 CT 显示咽旁脓肿和右颈内静脉血栓性静脉炎。患者随后被诊断为莱米埃尔综合征。第二天,患者的神经状况明显恶化。脑部核磁共振成像/MRA/MRV显示患者右侧颈内动脉狭窄,继发于血管炎、脑膜炎、静脉窦血栓形成和脑内脓肿的多个急性和亚急性梗死区域。颅内血管炎原发病因的检查结果均为阴性。虽然该病例通常表现为静脉疾病,但它突出显示了莱米埃尔综合征动脉受累和颅内并发症的罕见表现。临床医生应将血管炎和中枢神经系统受累视为莱米埃尔氏综合征的潜在并发症,而不是寻找不同的病因。
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引用次数: 0
Jejunal amyloidosis: Rare case with weight loss & altered bowel habits 空肠淀粉样变性:伴有体重减轻和排便习惯改变的罕见病例
Pub Date : 2024-07-26 DOI: 10.1093/bjrcr/uaae025
Hamid Majeed, Jie Fei Lau, Anna Davenport, Karim Muhammad, Farhat Bano
Amyloidosis is a multisystem disease characterized by the extracellular deposition of abnormal protein fibrils in various tissues and organs. It is a systemic disease mainly affecting the kidneys, liver, and spleen. In the GI tract, the duodenum is most commonly involved, followed by the stomach. We came across a relatively unusual case of jejunal amyloidosis where the presentation was with weight loss, abdominal pain, and changes in bowel habits. Radiological findings were non-specific, such as thickening of small bowel loops and small nodular bowel wall lesions, etc Endoscopic features were also not characteristic of any particular disease entity. Therefore, it was hard to narrow down the differential diagnosis based on endoscopy and clinic-radiological grounds. The diagnosis remained a mystery until the outcome of the final histopathology report. This case study will facilitate readers in considering this entity in the differential list if they encounter mimicking clinical and/or radiological features.
淀粉样变性是一种多系统疾病,其特征是异常蛋白质纤维在细胞外沉积在各种组织和器官中。它是一种全身性疾病,主要影响肾脏、肝脏和脾脏。在消化道,十二指肠最常受累,其次是胃。我们发现了一例相对罕见的空肠淀粉样变性病例,患者表现为体重减轻、腹痛和排便习惯改变。放射学检查结果无特异性,如小肠襻增粗、肠壁小结节性病变等,内镜特征也没有任何特定疾病实体的特征。因此,很难根据内镜和临床放射学依据缩小鉴别诊断范围。在最终的组织病理学报告结果出来之前,诊断仍然是个谜。本病例研究将有助于读者在遇到类似的临床和/或放射学特征时将其列入鉴别诊断清单。
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引用次数: 0
Malignant paraganglioma of the prostate invading the bladder and bilateral seminal vesicles: a case report 侵犯膀胱和双侧精囊的前列腺恶性副神经节瘤:病例报告
Pub Date : 2024-07-15 DOI: 10.1093/bjrcr/uaae024
Jian Tao, Haiyan Ma, Xianchun Zeng
Malignant paraganglioma (PGL) of the prostate is extremely rare, with only three cases reported in the English literature to date. In this article, we present a case of malignant prostatic PGL invading the bladder and bilateral seminal vesicles, in which the patient had a history of long-term hematuria and normal serum PSA level, and was misdiagnosed as a bladder tumor invading the prostate preoperatively. As this case belongs to functional tumor, there is a risk of developing hypertensive crisis during diagnostic biopsy or radical resection. The CT manifestations of prostatic PGL are characteristic, but its imaging features are rarely described due to the rarity of the tumor site. Meanwhile, improving the comprehensive understanding of CT, MRI, functional imaging and clinical features of prostate PGL is conducive to make the correct diagnosis before surgery and ensure the safety of surgical treatment.
前列腺恶性副神经节瘤(PGL)极为罕见,迄今为止英文文献中仅有三例报道。本文介绍了一例侵犯膀胱和双侧精囊的恶性前列腺副神经节瘤,患者有长期血尿史,血清 PSA 水平正常,术前被误诊为侵犯前列腺的膀胱肿瘤。由于该病例属于功能性肿瘤,在诊断性活检或根治性切除术中存在发生高血压危象的风险。前列腺 PGL 的 CT 表现具有特征性,但由于肿瘤部位罕见,其影像学特征很少被描述。同时,提高对前列腺PGL的CT、MRI、功能成像和临床特征的全面认识,有利于术前做出正确诊断,确保手术治疗的安全性。
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引用次数: 0
A case of atypical meningioma presenting spontaneous infarction: the findings of magnetic resonance imaging, including amide proton transfer-chemical exchange saturation transfer imaging 一例出现自发性脑梗死的非典型脑膜瘤:磁共振成像(包括酰胺质子转移-化学交换饱和转移成像)的发现
Pub Date : 2024-07-09 DOI: 10.1093/bjrcr/uaae023
E. Iida, Atsuo Inoue, M. Tanabe, Naohiko Kamamura, Katsuyoshi Ito
We report the MRI findings of a patient with an atypical meningioma who presented with spontaneous infarction. A 67-year-old man with histories of recurrent meningioma complained of left ocular protrusion and a subsequent biopsy revealed atypical meningioma. Contrast-enhanced CT showed a uniformly enhancing tumor in the left ethmoid sinus, but MRI 2 days later showed no enhancement on Gd-T1WI and severe diffusion restriction on DWI, indicating spontaneous infarction. APT-CEST imaging showed slight hypointensity in comparison to the normal brain with a mean MTR asymmetry value of 0.48%. Tumor regrowth was confirmed on MRI after 2 months. The recurrent tumor showed moderate diffusion restriction on DWI and hyperintensity with a mean MTR asymmetry value of 2.59% on APT-CEST imaging. The decreased signal on APT-CEST at the time of spontaneous infarction may have been attributed to intratumoral acidosis and loss of viable tumor. APT-CEST imaging is useful for evaluating the intratumoral condition and tumor viability of the infarcted or ischemic tumor.
我们报告了一名非典型脑膜瘤患者的磁共振成像结果,该患者出现了自发性脑梗塞。一名有复发性脑膜瘤病史的 67 岁男子主诉左眼球突出,随后的活组织检查发现了非典型脑膜瘤。对比增强 CT 显示左侧乙状窦有均匀增强的肿瘤,但 2 天后的 MRI 显示 Gd-T1WI 没有增强,而 DWI 有严重的弥散受限,表明是自发性梗死。APT-CEST 成像显示,与正常大脑相比,肿瘤密度略低,平均 MTR 不对称值为 0.48%。2 个月后,核磁共振成像证实肿瘤再生。复发肿瘤在 DWI 上显示中度弥散受限,在 APT-CEST 成像上显示高密度,平均 MTR 不对称值为 2.59%。自发性梗死时的 APT-CEST 信号减弱可能是由于瘤内酸中毒和有活力的肿瘤消失所致。APT-CEST 成像有助于评估梗死或缺血肿瘤的瘤内情况和肿瘤存活率。
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引用次数: 0
T-cell lymphoblastic lymphoma/leukemia involving bilateral breast: a case report 累及双侧乳房的 T 细胞淋巴细胞淋巴瘤/白血病:病例报告
Pub Date : 2024-04-25 DOI: 10.1093/bjrcr/uaae013
Jing Zhou, Mingxing Li, Ling Liao
T-cell lymphoblastic lymphoma of the breast represents a highly uncommon subtype of non-Hodgkin's lymphoma. This study presents a case of T-cell lymphoblastic lymphoma/acute lymphoblastic leukemia (T-LBL/ALL) in a 73-year-old female patient exhibiting bilateral breast masses, bilateral axillary lymphadenopathy, swollen lymph nodes in the left neck, and petechiae on the chest. The breast ultrasound revealed heterogeneous hypoechoic findings in the skin layer and subcutaneous tissue of the upper outer quadrant of both breasts. Contrast-enhanced ultrasound demonstrated rapid homogeneous hyperenhancement of bilateral breast masses, and with a small unenhanced area noted in the center of the left breast mass. The fine-needle aspiration cytology of bilateral axillary lymph nodes revealed metastatic adenocarcinoma, whereas the fine-needle aspiration cytology of the left cervical lymph nodes indicated non-Hodgkin's lymphoma. Biopsy of the breast mass demonstrated multifocal growth of lymphocyte-like cells, with immunohistochemical analysis confirming T-LBL/ALL. This case study outlines the clinical and contrast-enhanced ultrasound features of breast T-LBL/ALL.
乳腺T细胞淋巴母细胞淋巴瘤是非霍奇金淋巴瘤中非常少见的一种亚型。本研究介绍了一例 T 细胞淋巴母细胞淋巴瘤/急性淋巴母细胞白血病(T-LBL/ALL)病例,患者 73 岁,女性,双侧乳房肿块,双侧腋窝淋巴结肿大,左颈部淋巴结肿大,胸部有瘀斑。乳腺超声检查显示,双侧乳房外上象限的皮肤层和皮下组织出现异质低回声。对比增强超声显示,双侧乳房肿块呈快速均匀高回声,左侧乳房肿块中央有一小块未增强区。双侧腋窝淋巴结细针穿刺细胞学检查显示为转移性腺癌,而左侧宫颈淋巴结细针穿刺细胞学检查显示为非霍奇金淋巴瘤。乳房肿块活检显示淋巴细胞样细胞多灶性生长,免疫组化分析证实为T-LBL/ALL。本病例研究概述了乳腺T-LBL/ALL的临床和对比增强超声特征。
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引用次数: 0
MRI Findings in 1 Case of Primary Gallbladder Lymphoma 1 例原发性胆囊淋巴瘤的磁共振成像结果
Pub Date : 2024-04-18 DOI: 10.1093/bjrcr/uaae011
Xiaoxuan Wang, Min Sun, Liqing Kang
We describe a case of gallbladder extra-nodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT-ML). MALT-ML is rare, and its clinical manifestations are lack of specificity. A few cases have been reported, and no characteristic imaging features have been described. We discussed the challenges of MRI in diagnosing MALT-ML of gallbladder, especially in differentiating it from gallbladder cancer. We found a “comb-like” sign in the inner wall of gallbladder on T2WI, which maybe helpful in diagnosing gallbladder MALT-ML.
我们描述了一例胆囊结外粘膜相关淋巴组织边缘区B细胞淋巴瘤(MALT-ML)。MALT-ML非常罕见,其临床表现缺乏特异性。目前仅有少数病例报道,尚未描述其特征性影像学特征。我们讨论了磁共振成像在诊断胆囊MALT-ML,尤其是与胆囊癌鉴别时所面临的挑战。我们在 T2WI 上发现胆囊内壁有 "梳状 "征象,这可能有助于诊断胆囊 MALT-ML。
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引用次数: 0
Adenoma Mimicking Intraductal Papillary Neoplasm of the Bile Duct Arising in an Intrahepatic Biliary Duplication Cyst 肝内胆管重复囊肿中出现的胆管腺瘤模拟导管内乳头状肿瘤
Pub Date : 2024-04-10 DOI: 10.1093/bjrcr/uaae012
Yuichi Tsuji, Shimada Kotaro, Hiroyoshi Isoda, Takamichi Ishii, Yasuhide Takeuchi, Yuji Nakamoto
We report a case of a cystic liver tumour in a 47-year-old man with Peutz-Jeghers syndrome (PJS) who had undergone sclerotherapy at another hospital for a cyst in hepatic segment IV (S4) 7 years earlier. Based on the preoperative imaging findings, the patient was diagnosed with an intraductal papillary neoplasm of the bile duct. Percutaneous transhepatic portal vein embolization was performed to increase the residual liver volume, followed by resection of the three right hepatic lobes and the caudate lobe, biliary reconstruction, and portal vein reconstruction. Pathological examination revealed an adenoma arising in an intrahepatic biliary duplication cyst. Retrospectively, the preoperative diagnosis was difficult, but it aligned with previous reports of biliary duplication cysts due to its continuity with the bile duct. Additionally, intrahepatic biliary duplication cysts with tumour lesions or cases in which 18F-fluorodeoxyglucose positron emission tomography was performed have not been previously reported. Therefore, preoperatively listing this disease as a differential diagnosis was difficult. PJS and chronic inflammation associated with cyst sclerotherapy may have contributed to tumour development in the intrahepatic biliary duplication cyst.
我们报告了一例47岁的佩兹-杰格尔斯综合征(Peutz-Jeghers Syndrome,PJS)男性患者的肝脏囊性肿瘤病例,该患者7年前曾在另一家医院接受过肝脏第IV段(S4)囊肿的硬化治疗。根据术前影像学检查结果,患者被诊断为胆管导管内乳头状肿瘤。患者接受了经皮经肝门静脉栓塞术以增加残肝体积,随后切除了右肝三叶和尾状叶,进行了胆道重建和门静脉重建。病理检查结果显示,肝内胆管重复囊肿中长出了一个腺瘤。回想起来,虽然术前诊断很困难,但由于其与胆管的连续性,与之前关于胆道重复囊肿的报道一致。此外,肝内胆管重复囊肿伴有肿瘤病变或进行了18F-氟脱氧葡萄糖正电子发射断层扫描的病例此前也未见报道。因此,术前很难将这种疾病列为鉴别诊断。与囊肿硬化治疗相关的PJS和慢性炎症可能是肝内胆管重复囊肿肿瘤发生的诱因。
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引用次数: 0
Perforated amyand's hernia with an adenocarcinoma tumour presenting as a groin abscess 腹股沟脓肿伴有腺癌肿瘤的阿米安氏疝穿孔
Pub Date : 2024-03-06 DOI: 10.1093/bjrcr/uaae008
Emmanuel Gbegli, Ahmad Miremadi, Eva Mendes Serrao, Timothy J. Sadler
An Amyand’s hernia is an incarcerated inguinal hernia containing the appendix with or without appendicitis. This is a rare form of inguinal hernia, making up approximately 0.4—1% of all cases 1. As with any hernia, this may become strangulated at any time, leading to the loss of blood supply and further development of gangrene and complications. Clinically, this can present in a manner indistinguishable from other types of inguinal hernias. In addition, the appendix can be affected by its own set of pathological processes, such as infection, inflammation and malignancy. Not uncommonly both hernial and appendiceal complications coexist. The clinical diagnosis of an Amyand’s hernia remains challenging due to its low incidence and indistinct clinical presentation. At present, surgery is usually diagnostic and therapeutic. However, there is a growing number of recent reports showing the invaluable role of imaging on the diagnosis of Amyand’s hernias and associated complications 2 3. The correct and timely recognition of their imaging features including complications can optimise and expedite patient care by guiding diagnosis, treatment and prognosis. Here, we report for the first time the radiological and pathological findings of a patient with a unique complicated Amyand’s hernia, which posed a diagnostic challenge for the clinical and radiological teams.
阿米氏疝是一种嵌顿性腹股沟疝,内含阑尾,伴有或不伴有阑尾炎。这是一种罕见的腹股沟疝,约占所有病例的 0.4-1% 1。与任何疝气一样,这种疝气随时可能发生绞窄,导致失血,进一步发展为坏疽和并发症。临床表现与其他类型的腹股沟疝无异。此外,阑尾也会受到自身一系列病理过程的影响,如感染、炎症和恶性肿瘤。疝和阑尾并发症同时存在的情况并不少见。由于阿米氏疝发病率低且临床表现不明显,临床诊断仍具有挑战性。目前,手术通常用于诊断和治疗。然而,最近越来越多的报告显示,影像学检查在诊断阿米恩疝及相关并发症方面发挥着不可估量的作用 2 3。正确、及时地识别其影像学特征(包括并发症)可以指导诊断、治疗和预后,从而优化和加快患者护理。在此,我们首次报告了一名独特的复杂阿米恩疝患者的放射学和病理学结果,这给临床和放射团队带来了诊断上的挑战。
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引用次数: 0
Endovascular intervention to treat spontaneous carotid-cavernous fistula in a patient with Ehlers-Danlos syndrome with an access site anatomical variant 用血管内介入疗法治疗一名艾勒斯-丹洛斯综合征患者的自发性颈动脉-海绵状静脉瘘,该患者的入路部位存在解剖学变异
Pub Date : 2024-02-09 DOI: 10.1093/bjrcr/uaae006
Austin Jin Xian See, Abhishekh Hulegar Ashok, Yogish Joshi, Mathew Guilfoyle, T. C. See
Vascular Ehlers-Danlos Syndrome (vEDS) is a rare and potentially life-threatening inherited connective tissue disorder. Patients with vEDS can present with spontaneous arterial dissections and ruptured aneurysms. There are previous reports of large artery dissections and vessel rupture following conventional catheter diagnostic angiography. We present the case of a patient with vEDS who had spontaneous carotid-cavernous fistula (CCF) and visceral aneurysms, associated with a normal variant of corona mortis. A CCF was successfully treated with a transvenous approach with detachable coils.
血管性埃勒斯-丹洛斯综合征(vEDS)是一种罕见的、可能危及生命的遗传性结缔组织疾病。vEDS 患者会出现自发性动脉断裂和动脉瘤破裂。以前曾有报道称,传统的导管诊断血管造影术会导致大动脉断裂和血管破裂。我们介绍了一例患有自发性颈动脉-海绵状静脉瘘(CCF)和内脏动脉瘤并伴有正常变异性冠状动脉畸形的 vEDS 患者。我们采用带可拆卸线圈的经静脉方法成功治疗了一个 CCF。
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引用次数: 0
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BJR|Case Reports
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