Mohd Altaf Dar, Z. Qadrie, Mudasir Maqbool, I. Ara, Afshana Qadir
Type 3 diabetes, though not an officially recognized term in the medical field, pertains to the potential correlation between insulin resistance and Alzheimer’s disease (AD). Insulin, known for its role in regulating glucose levels, also plays a vital part in brain function, supporting cognition and memory consolidation. Emerging studies propose that insulin resistance, a characteristic of type 2 diabetes, may extend to the brain, affecting glucose metabolism and neural activity. Research indicates that individuals with AD demonstrate reduced insulin sensitivity in the brain, contributing to the accumulation of amyloid plaques and tau tangles, which are characteristic features of the disease. This has led some experts to propose the notion of “type 3 diabetes” to describe the association between insulin resistance and Alzheimer’s. Understanding type 3 diabetes carries substantial implications for both research and treatment. Exploring insulin-sensitizing medications and lifestyle interventions to enhance brain insulin sensitivity could offer potential avenues to address the metabolic and cognitive aspects of the condition. However, type 3 diabetes remains a complex and evolving field of study, and the precise mechanisms linking insulin resistance to Alzheimer’s necessitate further investigation. While the concept is captivating, it is crucial to acknowledge that AD is influenced by numerous factors, and type 3 diabetes represents only one aspect of the intricate relationship between these two conditions.
{"title":"Metabolic mysteries of the mind: Investigating type 3 diabetes","authors":"Mohd Altaf Dar, Z. Qadrie, Mudasir Maqbool, I. Ara, Afshana Qadir","doi":"10.1515/ohe-2023-0025","DOIUrl":"https://doi.org/10.1515/ohe-2023-0025","url":null,"abstract":"\u0000 Type 3 diabetes, though not an officially recognized term in the medical field, pertains to the potential correlation between insulin resistance and Alzheimer’s disease (AD). Insulin, known for its role in regulating glucose levels, also plays a vital part in brain function, supporting cognition and memory consolidation. Emerging studies propose that insulin resistance, a characteristic of type 2 diabetes, may extend to the brain, affecting glucose metabolism and neural activity. Research indicates that individuals with AD demonstrate reduced insulin sensitivity in the brain, contributing to the accumulation of amyloid plaques and tau tangles, which are characteristic features of the disease. This has led some experts to propose the notion of “type 3 diabetes” to describe the association between insulin resistance and Alzheimer’s. Understanding type 3 diabetes carries substantial implications for both research and treatment. Exploring insulin-sensitizing medications and lifestyle interventions to enhance brain insulin sensitivity could offer potential avenues to address the metabolic and cognitive aspects of the condition. However, type 3 diabetes remains a complex and evolving field of study, and the precise mechanisms linking insulin resistance to Alzheimer’s necessitate further investigation. While the concept is captivating, it is crucial to acknowledge that AD is influenced by numerous factors, and type 3 diabetes represents only one aspect of the intricate relationship between these two conditions.","PeriodicalId":518557,"journal":{"name":"Open Health","volume":"34 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140532612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The rise of food delivery apps has ushered in a new era in the way we consume meals, bringing both unprecedented convenience and concerns about their impact on obesity. These digital platforms, exemplified by industry giants like Uber Eats and DoorDash, have transformed the dining experience from a trip to the kitchen to a simple click on our smartphones. While the seamless accessibility to a diverse range of culinary options is undoubtedly a game-changer, it comes with a flip side. The ease of ordering restaurant-quality meals, fast food, or groceries through these apps may contribute to less health-conscious dietary choices. The convenience factor might inadvertently lead to an overreliance on high-calorie and less nutritious options, potentially exacerbating the obesity epidemic. As we navigate this digital culinary landscape, it becomes imperative to understand and address the implications of this technological shift on public health. Research and awareness campaigns are vital to comprehending the nuanced relationship between food delivery apps and obesity, ensuring that the ease of a click does not translate into a surge in calories. Balancing the advantages of convenience with the potential risks to our health is paramount as we strive for a harmonious coexistence with these technological innovations.
{"title":"From click to calories: Navigating the impact of food delivery apps on obesity","authors":"Michael M. Willie, Mudasir Maqbool, Afshana Qadir","doi":"10.1515/ohe-2023-0022","DOIUrl":"https://doi.org/10.1515/ohe-2023-0022","url":null,"abstract":"\u0000 The rise of food delivery apps has ushered in a new era in the way we consume meals, bringing both unprecedented convenience and concerns about their impact on obesity. These digital platforms, exemplified by industry giants like Uber Eats and DoorDash, have transformed the dining experience from a trip to the kitchen to a simple click on our smartphones. While the seamless accessibility to a diverse range of culinary options is undoubtedly a game-changer, it comes with a flip side. The ease of ordering restaurant-quality meals, fast food, or groceries through these apps may contribute to less health-conscious dietary choices. The convenience factor might inadvertently lead to an overreliance on high-calorie and less nutritious options, potentially exacerbating the obesity epidemic. As we navigate this digital culinary landscape, it becomes imperative to understand and address the implications of this technological shift on public health. Research and awareness campaigns are vital to comprehending the nuanced relationship between food delivery apps and obesity, ensuring that the ease of a click does not translate into a surge in calories. Balancing the advantages of convenience with the potential risks to our health is paramount as we strive for a harmonious coexistence with these technological innovations.","PeriodicalId":518557,"journal":{"name":"Open Health","volume":"2 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140532787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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