Biotechnology for the environment最新文献

英文中文

Detection of environmental pollutants using transcription factor-based whole-cell biosensors. 利用基于转录因子的全细胞生物传感器检测环境污染物。

Biotechnology for the environment

Pub Date : 2025-01-01 Epub Date: 2025-12-01 DOI: 10.1186/s44314-025-00032-7

Yuan Dou, Jianli Zhang, Xinyu Gong, Qi Gan, Shuo Yu, Yajun Yan

The widespread presence of heavy metals and aromatic compounds in environmental systems has emerged as a critical global concern. While conventional analytical methods such as spectroscopy and chromatography provide high precision, their substantial costs and labor-intensive procedures significantly limit their practical application in routine environmental monitoring. Transcription factor-based whole-cell biosensors represent a promising alternative technology, providing real-time, highly sensitive, and cost-effective detection capabilities for environmental pollutants. This review is a comprehensive examination of the recent advances in transcription factor-based biosensors for detecting heavy metals and aromatic compounds. We also emphasize the molecular mechanisms of diverse TF families and their real-world applications in environmental monitoring. Finally, we summarize the current engineering strategies that are employed to enhance biosensor performance and discuss future directions for improving transcription factor-based biosensors for environmental detection.

重金属和芳香族化合物在环境系统中的广泛存在已成为全球关注的一个重要问题。虽然传统的分析方法，如光谱学和色谱法提供了很高的精度，但它们的巨大成本和劳动密集型的程序极大地限制了它们在日常环境监测中的实际应用。基于转录因子的全细胞生物传感器代表了一种很有前途的替代技术，为环境污染物提供实时、高灵敏度和低成本的检测能力。本文综述了近年来基于转录因子的重金属和芳香族化合物生物传感器的研究进展。我们还强调了不同TF家族的分子机制及其在环境监测中的实际应用。最后，我们总结了目前用于提高生物传感器性能的工程策略，并讨论了改进基于转录因子的环境检测生物传感器的未来方向。

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引用次数: 0

Investigation of medicinal plant processing waste for electricity generation through biomethanation 药用植物加工废料生物甲烷化发电研究

Biotechnology for the environment

Pub Date : 2024-07-15 DOI: 10.1186/s44314-024-00004-3

Kartikeya Nayak, V. Kumargouda, Kavan Kumar

引用次数: 0

Engineered plastic-associated bacteria for biodegradation and bioremediation. 用于生物降解和生物修复的工程塑料相关细菌。

Biotechnology for the environment

Pub Date : 2024-01-01 Epub Date: 2024-07-15 DOI: 10.1186/s44314-024-00007-0

Arianna Schneier, Gavin Melaugh, Joanna C Sadler

The global plastic waste crisis has triggered the development of novel methods for removal of recalcitrant polymers from the environment. Biotechnological approaches have received particular attention due to their potential for enabling sustainable, low-intensity bioprocesses which could also be interfaced with microbial upcycling pathways to support the emerging circular bioeconomy. However, low biodegradation efficiency of solid plastic materials remains a bottleneck, especially at mesophilic conditions required for one-pot degradation and upcycling. A promising strategy used in nature to address this is localisation of plastic-degrading microbes to the plastic surface via biofilm-mediated surface association. This review highlights progress and opportunities in leveraging these naturally occurring mechanisms of biofilm formation and other cell-surface adhesion biotechnologies to co-localise engineered cells to plastic surfaces. We further discuss examples of combining these approaches with extracellular expression of plastic-degrading enzymes to accelerate plastic degradation. Additionally, we review this topic in the context of nano- and microplastics bioremediation and their removal from wastewater and finally propose future research directions for this nascent field.

全球塑料废物危机引发了从环境中去除难降解聚合物的新方法的开发。生物技术方法因其在实现可持续、低强度生物工艺方面的潜力而受到特别关注，这些工艺还可与微生物升级再循环途径相结合，以支持新兴的循环生物经济。然而，固体塑料材料的生物降解效率低仍然是一个瓶颈，尤其是在单锅降解和升级再循环所需的中亲水性条件下。在自然界中，解决这一问题的一个可行策略是通过生物膜介导的表面联合，将降解塑料的微生物定位到塑料表面。本综述重点介绍了利用这些自然形成的生物膜机制和其他细胞表面粘附生物技术将工程细胞共定位到塑料表面的进展和机遇。我们进一步讨论了将这些方法与细胞外表达塑料降解酶相结合以加速塑料降解的实例。此外，我们还从纳米和微塑料生物修复以及从废水中去除塑料的角度回顾了这一主题，最后为这一新兴领域提出了未来的研究方向。

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