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Cognitive screening and education: assessing the Montreal Cognitive Assessment's validity in older Ugandan populations. 认知筛选和教育:评估蒙特利尔认知评估在乌干达老年人群中的有效性。
Pub Date : 2025-01-01 Epub Date: 2025-07-18 DOI: 10.20935/mhealthwellb7804
Kamada Lwere, Haruna Muwonge, Hakim Sendagire, Joy Louise Gumikiriza-Onoria, Rheem Nakimbugwe, Denis Buwembo, Noeline Nakasujja, Mark Kaddumukasa

Background: Cognitive screening tools such as the Montreal Cognitive Assessment (MoCA) are widely used to detect cognitive impairments. However, their accuracy in low- and middle-income countries (LMICs) may be affected by variations in educational levels. This study examined the impact of educational attainment on MoCA performance in older Ugandan adults, considering sex- and age-related differences.

Methods: A cross-sectional study was conducted in Wakiso District, Uganda, involving adults aged ≥ 65 years. Their MoCA scores were analyzed in relation to their educational attainment, sex, and age. Multiple linear regression models were used to determine the independent effect of education on cognitive performance after adjusting for age and sex. Sensitivity analyses were conducted using multiple imputations for missing data.

Results: Higher educational attainment was significantly associated with a better MoCA performance (β = 1.73, 95% CI: 1.22-2.24, p < 0.001). Age was negatively associated with MoCA scores (β = -0.13, 95% CI: -0.19 to -0.07, p < 0.001), whereas male sex was positively associated (β = 1.89, 95% CI: 0.56-3.22, p = 0.005). The interaction terms (education × sex and education × age) were not significant, indicating that the effect of education was consistent across demographic subgroups. The final regression model explained 42.7% of the variance in the MoCA scores (adjusted R2 = 0.43, p < 0.001). The sensitivity analysis confirmed the robustness of the findings.

Conclusions: Educational attainment impacts MoCA performance in older Ugandans, highlighting the need for region-specific norms and culturally adapted cognitive screening in LMICs.

背景:认知筛查工具如蒙特利尔认知评估(MoCA)被广泛用于检测认知障碍。然而,它们在低收入和中等收入国家(LMICs)的准确性可能受到教育水平差异的影响。本研究考察了教育程度对乌干达老年人MoCA表现的影响,考虑了性别和年龄相关的差异。方法:在乌干达Wakiso地区进行了一项横断面研究,涉及年龄≥65岁的成年人。他们的MoCA分数与他们的受教育程度、性别和年龄有关。在调整年龄和性别后,采用多元线性回归模型确定教育对认知表现的独立影响。敏感性分析采用对缺失数据的多重输入进行。结果:较高的教育程度与较好的MoCA表现显著相关(β = 1.73, 95% CI: 1.22-2.24, p < 0.001)。年龄与MoCA评分呈负相关(β = -0.13, 95% CI: -0.19 ~ -0.07, p < 0.001),而男性与MoCA评分呈正相关(β = 1.89, 95% CI: 0.56 ~ 3.22, p = 0.005)。相互作用项(教育×性别和教育×年龄)不显著,表明教育的影响在人口统计亚组中是一致的。最终回归模型解释了42.7%的MoCA评分方差(调整后R2 = 0.43, p < 0.001)。敏感性分析证实了研究结果的稳健性。结论:受教育程度会影响乌干达老年人的MoCA表现,这突出了中低收入国家需要制定地区特定规范和文化适应的认知筛查。
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引用次数: 0
Mental and behavioral health care access and satisfaction among older sexual minority women. 老年性少数群体妇女的心理和行为卫生保健获取和满意度。
Pub Date : 2025-01-01 Epub Date: 2025-08-26 DOI: 10.20935/mhealthwellb7867
Jillian R Scheer, Gabriella Epshteyn, Rachel Girard, Michelle A Stage, Elizabeth M Chadbourne, Billy A Caceres, Melanie M Wall, Tonda L Hughes

This study expands upon syndemics, structural vulnerability, and health care utilization frameworks by examining individual and social factors influencing help-seeking, care barriers, and treatment satisfaction among sexual minority women (SMW; e.g., bisexual, lesbian) aged 50+ from Wave 3 of a community-based longitudinal study, the Chicago Health and Life Experiences of Women Study. Wave 3 data were collected in 2010-2012 (May 2010 to August 2012). Bivariate analyses were conducted to examine associations among help-seeking behaviors, self-rated physical and mental health, relationship status, and social support. We used multivariate logistic regression models to examine (1) associations between sociodemographic characteristics and help-seeking, (2) associations between help-seeking and treatment satisfaction variables and sociodemographic characteristics, (3) self-rated physical health and self-rated mental health as predictors of help-seeking and treatment satisfaction, and (4) interpersonal factors as predictors of help-seeking and treatment satisfaction. Participants (N = 196) were, on average, 58.15 years of age (SD = 6.61). Physical health and issues related to depression, anxiety, memory, and eating are synergistic among older SMW. Those with insufficient household incomes and identifying as bisexual, Black, or younger were more likely to seek help. Black and Latinx SMW reported fewer help-seeking barriers than White SMW. Self-rated poorer mental health was associated with greater difficulty accessing services; sociodemographic variables weakened this association. Poorer mental health and lower social support were associated with treatment dissatisfaction. Results highlight the relevance of structural vulnerabilities and social determinants of health among older SMW, emphasizing the need for integrated, culturally competent care models that enhance access and improve treatment satisfaction.

本研究通过考察影响50岁以上的性少数群体妇女(SMW,如双性恋、女同性恋)寻求帮助、护理障碍和治疗满意度的个人和社会因素,扩展了综合症、结构脆弱性和医疗保健利用框架。这些因素来自一项基于社区的纵向研究,芝加哥妇女健康和生活经历研究。第三波数据收集于2010-2012年(2010年5月至2012年8月)。采用双变量分析来检验求助行为、自评身心健康、人际关系状况和社会支持之间的关系。我们使用多元逻辑回归模型来检验(1)社会人口学特征与寻求帮助之间的关系,(2)寻求帮助和治疗满意度变量与社会人口学特征之间的关系,(3)自评身体健康和自评心理健康作为寻求帮助和治疗满意度的预测因子,(4)人际因素作为寻求帮助和治疗满意度的预测因子。参与者(N = 196)的平均年龄为58.15岁(SD = 6.61)。身体健康和与抑郁、焦虑、记忆和饮食相关的问题在老年SMW中是协同的。那些家庭收入不足、双性恋、黑人或更年轻的人更有可能寻求帮助。黑人和拉丁裔家庭主妇在寻求帮助方面的障碍比白人家庭主妇少。自我评价较差的心理健康状况与获得服务的难度较大有关;社会人口变量削弱了这种联系。较差的心理健康状况和较低的社会支持与治疗不满有关。研究结果强调了结构脆弱性与老年SMW健康的社会决定因素之间的相关性,强调需要综合的、文化上合格的护理模式,以增加获得和提高治疗满意度。
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引用次数: 0
Social-emotional learning program: a community-based case-controlled study. 社会情绪学习计划:基于社区的病例对照研究。
Pub Date : 2024-01-01 Epub Date: 2024-08-13 DOI: 10.20935/mhealthwellb7308
Kit Knier, Taylor Harrison, Michelle Grady, Andrew Brock, Gauri Sood, Debbie Fuehrer, Amit Sood, Chris Pierret

HappiGenius is a mindfulness-based social-emotional learning (SEL) program developed and initially deployed in the context of COVID-19. Novel features of the HappiGenius program include the use of behavioral practice and activities to enhance traditional classroom-based learning, the capability to teach in a remote setting, and a focus on internalizing behaviors in addition to traditionally targeted externalizing behaviors. A pilot study of four third-grade classrooms completed in the previous academic year showed promising results for improvements in students' experience of positive affect, self-compassion, total difficulties, and prosocial behaviors. This quasi-experimental case-control study was conducted in 14 third-grade classrooms across four schools in a midsize Midwestern US city. We hypothesized that HappiGenius would lead to improvements in positive affect, self-compassion, and mindfulness, in addition to other social behaviors measured by quantitative standardized scales. We used qualitative methodology to determine whether HappiGenius was feasible and acceptable to teachers for use in the classroom. While there was no statistically significant change in positive affect, self-compassion, or mindfulness, there was meaningful improvement in student internalizing problems and peer problems. Analysis of qualitative data showed the importance of timing during the year to maximize classroom benefits like establishing behavioral expectations early and reducing problem behaviors. The study represents a step in the direction of evaluating the implementation and outcomes of a new social-emotional learning program developed with deliberate attention to internalizing problems alongside traditionally studied externalizing problems.

HappiGenius是一款基于正念的社交情绪学习(SEL)程序,最初是在COVID-19的背景下开发和部署的。HappiGenius项目的新特点包括使用行为实践和活动来增强传统的基于课堂的学习,远程教学的能力,以及在传统的针对性外化行为之外关注内化行为。在上一学年完成的一项针对四间三年级教室的试点研究显示,在改善学生的积极情感体验、自我同情、总困难和亲社会行为方面取得了可喜的成果。这项准实验病例对照研究在美国中西部一个中型城市的四所学校的14个三年级教室中进行。我们假设HappiGenius会导致积极影响、自我同情和正念方面的改善,以及其他通过定量标准化量表衡量的社会行为。我们使用定性方法来确定HappiGenius在课堂上使用是否可行和可接受。虽然在积极影响、自我同情或正念方面没有统计学上的显著变化,但在学生的内化问题和同伴问题方面有显著改善。对定性数据的分析表明,在一年中选择适当的时间,可以最大限度地提高课堂效益,比如及早建立行为预期,减少问题行为。这项研究是在评估一项新的社会情感学习计划的实施和结果的方向上迈出的一步,该计划是在传统研究外化问题的同时,也有意关注内化问题。
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引用次数: 0
Measuring the quality of self-care of elderly patients with dementia in a developing country. 衡量发展中国家老年痴呆症患者的自我护理质量。
Pub Date : 2024-01-01 Epub Date: 2024-07-31 DOI: 10.20935/mhealthwellb7300
Dennis Rogers Buwembo, Joy Louise Gumikiriza-Onoria, Lwere Kamada, Mark Kaddu-Mukasa, Joseph Kagaayi, Juliet Kiguli, Martha Sajatovic, Noeline Nakasujja, Fredrick Makumbi

In developing countries like Uganda, people with dementia are cared for by non-medically trained family members with minimal support from the formal healthcare system. The quality of care in this setting is largely unknown but significantly affects the well-being of those with dementia. A tool designed to measure the quality of informal care for old frail adults with or without dementia was translated into Luganda. A committee of experts reviewed and finalized the translation, which was pilot-tested and then used to measure the quality of dementia self-care. We consecutively enrolled 105 caregivers of elderly people with dementia; the median age was 35 years (Interquartile Range 26-47 years), and 67% were females, taking care of a grandparent (44%) or a parent (34%). We used confirmatory factor analysis to assess for structural validity and computed correlation coefficients and Cronbach's alpha to assess for discriminant validity and internal reliability, respectively. The three-factor model applied to the 20 items, adequately fit the data (Comparative Fit Index = 0.88, Tucker-Lewis Index = 0.87, Root Mean Square Error of Approximation = 0.08; 90% Confidence Interval (0.06-0.09), Standardized Root Mean Square Residual = 0.089). There was good discriminant validity, and correlation coefficients between dimensions/scales and the Dementia Knowledge Assessment Scale scores were low. There was good internal reliability with all items Cronbach's alpha ranging from 0.69 to 0.89. Our findings demonstrated that this culturally adapted, shorter measurement tool is valid and reliable. The tool can be used by researchers, health workers, and agencies to assess the quality of self-care for elderly people with dementia in Uganda.

在乌干达等发展中国家,痴呆症患者由未受过医疗培训的家庭成员照顾,正规医疗系统提供的支持微乎其微。在这种情况下,护理质量在很大程度上是未知的,但却对痴呆症患者的福祉产生着重大影响。我们将一种旨在衡量为患有或未患有痴呆症的年老体弱成年人提供的非正式护理质量的工具翻译成了卢干达语。专家委员会对译文进行了审阅和定稿,并对其进行了试点测试,然后用于测量痴呆症患者的自我护理质量。我们连续招募了 105 名痴呆症老人的照护者,其中年龄中位数为 35 岁(四分位数区间为 26-47 岁),67% 为女性,照护者为祖父母(44%)或父母(34%)。我们采用确认性因子分析评估结构有效性,并计算相关系数和克朗巴赫α,分别评估判别有效性和内部可靠性。适用于 20 个项目的三因素模型充分拟合了数据(比较拟合指数 = 0.88,塔克-刘易斯指数 = 0.87,近似均方根误差 = 0.08;90% 置信区间(0.06-0.09),标准化均方根残差 = 0.089)。各维度/量表与痴呆知识评估量表得分之间的相关系数较低。内部信度良好,所有项目的 Cronbach's alpha 均在 0.69 至 0.89 之间。我们的研究结果表明,这一经过文化调整的简短测量工具是有效和可靠的。研究人员、卫生工作者和机构可以使用该工具来评估乌干达老年痴呆症患者的自我护理质量。
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引用次数: 0
Feasibility and acceptability of the World Health Organization's iSUPPORT program for dementia caregivers in Uganda. 世界卫生组织乌干达老年痴呆症护理人员iSUPPORT方案的可行性和可接受性。
Pub Date : 2024-01-01 Epub Date: 2024-08-12 DOI: 10.20935/mhealthwellb7292
Joy Louise Gumikiriza-Onoria, Roy William Mayega, Janet Nakigudde, Bruno Giordani, Martha Sajatovic, Mark Kaddu Mukasa, Dennis Buwembo, Kamada Lwere, Noeline Nakasujja

This study aims to address Alzheimer's disease and related dementias (ADRD) in low- and middle-income countries (LMICs). It involves adaptation of the World Health Organization's iSUPPORT (WHO-iSUPPORT) psychosocial intervention for Uganda, assessing its feasibility and acceptability, and its effects on caregivers' psychological distress, quality of life (QoL), and depression levels. The adapted iSUPPORT (UGA-iSUPPORT) program was translated into Luganda, a local language, validated by experts, divided into four modules, and later piloted for four weeks in Wakiso, Uganda. The caregivers were randomly assigned to receive weekly UGA-iSUPPORT sessions or modified standard care via weekly phone consultations. Baseline and endpoint changes were assessed using the Kessler Psychological Distress Scale (K-10), the Centre for Epidemiological Studies Depression Scale (CES-D), and the Measure of Quality of Life for Dementia Caregivers (C-DEMQOL). The intervention group (n = 33, 87.9% females, mean age 32.5 years) showed significant improvements in psychological distress (decreased from 29.2 to 23.7, p = 0.001), depression (from 33.4 to 25.6, p = 0.001), and QoL (from 81.1 to 89.4, p = 0.001). The control group (n = 32, 50% female, mean age 36.7 years) did not experience similar enhancements. The high retention rate (97%) and positive feedback from the participants underscored the program's feasibility and acceptability. UGA-iSUPPORT effectively boosted the mental health and well-being of dementia caregivers in LMICs. This study highlights the necessity of enduring and expandable interventions within healthcare systems. Further studies are warranted to examine these interventions' prolonged impacts.

本研究旨在解决中低收入国家(LMICs)的阿尔茨海默病和相关痴呆(ADRD)问题。它涉及调整世界卫生组织的iSUPPORT(世卫组织-iSUPPORT)乌干达社会心理干预措施,评估其可行性和可接受性,及其对照顾者心理困扰、生活质量和抑郁水平的影响。经过改编的iSUPPORT (UGA-iSUPPORT)项目被翻译成当地语言卢甘达语,经过专家验证,分为四个模块,随后在乌干达瓦基索进行了为期四周的试点。护理人员被随机分配接受每周UGA-iSUPPORT会议或通过每周电话咨询修改的标准护理。基线和终点变化采用Kessler心理困扰量表(K-10)、流行病学研究中心抑郁量表(CES-D)和痴呆症护理者生活质量测量量表(C-DEMQOL)进行评估。干预组(n = 33,女性87.9%,平均年龄32.5岁)在心理困扰(从29.2降至23.7,p = 0.001)、抑郁(从33.4降至25.6,p = 0.001)和生活质量(从81.1降至89.4,p = 0.001)方面均有显著改善。对照组(n = 32, 50%为女性,平均年龄36.7岁)没有出现类似的改善。高保留率(97%)和参与者的积极反馈强调了该计划的可行性和可接受性。UGA-iSUPPORT有效地促进了中低收入国家痴呆症护理人员的心理健康和福祉。这项研究强调了在卫生保健系统内采取持久和可扩展的干预措施的必要性。有必要进一步研究这些干预措施的长期影响。
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