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Studies on COVID-19 lethality: Causes and dynamics at German University Hospitals 新冠肺炎致死率研究:德国大学医院的原因和动态
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2021-01-01 DOI: 10.19224/ai2021.244
J. Schüttler, J. Mang, L. Kapsner, S. Seuchter, H. Binder, D. Zoller, O. Kohlbacher, M. Boeker, K. Zacharowski, G. Rohde, J. Balig, M. Kampf, R. Rohrig, H. Prokosch
Background: In the initial phase of the COVID-19 pandemic, a lower incidence and death rate was observed in Germany compared to its neighbouring countries, but some studies showed comparatively high death rates in ventilated COVID-19 patients. Methods: In this retrospective analysis, hospital stays of COVID-19 patients at 14 German university hospitals were analysed. For this purpose, local data integration centres of the German Medical Informatics Initiative (MII) combined their data to present death rates in different subgroups depending on gender, age, length of stay in the intensive care unit, ventilation and in combination with different comorbidities. Results: The total lethality rate in 1,318 COVID-19 patients was 18.8 %. In ventilated cases, the lethality rate was 38.8%. Common comorbidities were renal insufficiency (35.2 %), aplastic and other anaemia (26.0 %) diabetes mellitus (21.1 %). The average length of stay was 18 days, or 28 days in case of ventilated patients. Lethality decreased from 20.7 % to 12.7 % over the observation period. Conclusion: The observed decline in lethality rates may be explained with the continuous optimisation of COVID-19 treatment, increasing experience and improved therapy recommendations. The progress made so far by the MII allows cross-consortium analyses to be carried out just in time to better address the challenges of the COVID-19 pandemic.
背景:在新冠肺炎大流行初期,德国的发病率和死亡率低于邻国,但一些研究显示,新冠肺炎通气患者的死亡率相对较高。方法:回顾性分析德国14所大学附属医院的COVID-19患者住院情况。为此目的,德国医学信息学倡议(MII)的地方数据整合中心将其数据结合起来,根据性别、年龄、在重症监护病房的住院时间、通气情况以及不同的合并症,列出了不同亚组的死亡率。结果:1318例新冠肺炎患者总病死率为18.8%。通风病例病死率为38.8%。常见合并症为肾功能不全(35.2%)、再生障碍性贫血及其他贫血(26.0%)、糖尿病(21.1%)。平均住院时间18天,通气患者平均住院时间28天。在观察期间,致死率从20.7%下降到12.7%。结论:观察到的死亡率下降可能与COVID-19治疗的不断优化,经验的增加和治疗建议的改进有关。MII迄今取得的进展使跨联盟分析能够及时进行,以更好地应对COVID-19大流行的挑战。
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引用次数: 0
New treatment approaches and the dilemma of medical ethics and economics using haemoadsorption with Cytosorb 用Cytosorb进行血液吸附的新治疗方法及医学伦理和经济学困境
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2021-01-01 DOI: 10.19224/AI2021.193
T. Datzmann, S. Sausmann, H. Reinelt, K. Träger
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引用次数: 0
Objektive Verlegungskriterien und proaktives Verlegungs­management zur Steuerung von intensivmedizinischen Kapazitäten 合理部署标准和主动部署管理来控制高精卫医疗能力
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2020-12-01 DOI: 10.19224/AI2020.569
M. Hiller, K. Spohn, J. Schütte, H. Bracht, Laura Hering, J. Bakker, S. Schröder
Despite the high number of intensive care beds in German hospitals compared to other European countries, intensive care medical shortages are common in daily clinical practice. This is due to a hardly established cross-departmental discharge and transfer management with missing objective discharge criteria, lack of personnel and bed closures. Aboveaverage lengths of stays and increased readmission rates to the intensive care unit also indicate an inefficient use of resources in German hospitals. Against this background, a systematic literature search was carried out on the current state of research on discharge criteria from the intensive care unit and transfer processes to follow-up wards. Between 1983 and 2020, 1,917 sources were found, 286 were selected as full text, 104 of which were considered relevant and used as the basis for this work. Approaches, such as a root cause analy- sis of bottleneck situations including the entire hospital system with its interdependent admission, transfer and discharge processes, and the use of electronic decision support in conjunction with standardised discharge criteria can improve the use of existing intensive care capacities and lead to safer and better patient flow. For better use of resources, the therapeutic outcome must be viewed along the entire clinical pathway in order to care for the right patient at the right place and at the right time. A standardised care transition management using objective discharge criteria could help to include the various stakeholders in the discharge decision and patient-transfer process to reflect patient-, caregiver-, process, and institution-specific factors, and ultimately to manage, proactively and efficiently, the available intensive care resources. Decision support in the discharge process using self-learning systems based on available data from patient data management systems is forward-looking, but must be validated more widely in clinical practice.
尽管与其他欧洲国家相比,德国医院的重症监护病床数量较多,但重症监护医疗短缺在日常临床实践中很常见。这是由于几乎没有建立跨部门的出院和转院管理,缺乏客观的出院标准,缺乏人员和床位关闭。住院时间超过平均水平,重症监护室再入院率增加,也表明德国医院资源利用效率低下。在此背景下,我们对重症监护病房的出院标准和转院流程的研究现状进行了系统的文献检索。1983年至2020年共发现文献1917份,选取全文286份,其中认为相关文献104份作为本工作的基础。诸如瓶颈情况的根本原因分析,包括整个医院系统及其相互依赖的入院、转院和出院流程,以及结合标准化出院标准使用电子决策支持等方法,可以改善现有重症监护能力的使用,并导致更安全和更好的患者流动。为了更好地利用资源,必须沿着整个临床路径来观察治疗结果,以便在正确的地点和正确的时间照顾正确的病人。使用客观出院标准的标准化护理过渡管理可以帮助包括出院决策和患者转移过程中的各种利益相关者,以反映患者,护理人员,过程和机构特定因素,并最终积极有效地管理可用的重症监护资源。在出院过程中使用基于患者数据管理系统中可用数据的自我学习系统的决策支持具有前瞻性,但必须在临床实践中得到更广泛的验证。
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引用次数: 0
Entwicklung eines zentral gesteuerten Ausbildungs- und Ausstattungs­konzepts für innerklinische Notfälle 开发一个中央控制的培训和部门应急概念
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2020-01-01 DOI: 10.19224/AI2020.040
H. Gässler, B. Hossfeld, J. Gräsner, M. Helm
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引用次数: 0
Anaesthesia recommendations for Kleefstra Syndrome Kleefstra综合征的麻醉建议
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2020-01-01 DOI: 10.19224/AI2020.S358
C. Abdallah
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引用次数: 0
Influence of a structured training on the application of mechanical chest compression devices 结构化训练对机械胸外按压装置应用的影响
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2019-01-01 DOI: 10.19224/ai2019.104
Holger Gaessler, S. Decken, L. Lampl, M. Helm
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引用次数: 0
Prehospital capnometry as quality indicator for trauma patients - initial analysis from the TraumaRegister DGU (R) 院前血糖测定作为创伤患者的质量指标——来自创伤登记DGU (R)的初步分析
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2019-01-01 DOI: 10.19224/ai2019.419
A. Wilharm, M. Kulla, M. Baacke, F. Wagner, M. Behnke, R. Lefering, H. Trentzsch, TraumaRegister Dgu
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引用次数: 0
Inhospital Management of major incidents and disasters - the importance of anaesthesiology 医院重大事故和灾害的管理——麻醉学的重要性
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2019-01-01 DOI: 10.19224/ai2019.389
T. Wurmb, T. Kerner, G. Geldner, G. Schaelte, A. Heller, B. Hossfeld, Jan-Thorsten Graesner
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引用次数: 1
Functionality and operational fitness of mechanical chest compression devices 机械胸外按压装置的功能和操作适应性
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2019-01-01 DOI: 10.19224/ai2019.113
Dominik Treffer, A. Weissleder, Holger Gaessler, S. Decken, Maximilian Hauptkorn, M. Helm
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引用次数: 2
Die aneurysmatisch bedingte Subarachnoidalblutung: Update 动脉瘤下出血更新
IF 0.7 4区 医学 Q3 Medicine Pub Date : 2017-01-01 DOI: 10.19224/AI2017.481
A. D. Rieg, G. Schubert, H. Schulze‐Steinen, R. Rossaint, G. Schaelte, G. Marx, M. Coburn
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引用次数: 0
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