首页 > 最新文献

口腔学期刊(英文)最新文献

英文 中文
Comparison of Success Rate and Radiological Bone Loss in Patients with Mini-Implant versus Conventional-Sized Implant Removable Prostheses: A Meta-Analysis 微型种植体与常规种植体可移除假体患者的成功率和放射性骨丢失的比较:Meta分析
Pub Date : 2021-02-03 DOI: 10.4236/OJST.2021.112006
Khaled Abubaker, Yuzhou Li, Sheng Yang
Background: The objective of this meta-analysis was to assess whether mini-implants have added benefit in terms of implants success rate and average bone loss over conventional-sized implants after one year of follow-up. Methods: An electronic search of randomized clinical trials was conducted in MEDLINE (via PubMed), Cochrane Central Register of Clinical Trials (CENTRAL) and Web of Science for studies including complete or partial edentulous patients requiring two or four mini-implants or conventional/ standard-sized implants in the maxilla or mandible for implant-supported removable prostheses who completed 12 months of follow-up. Results: The search provided 194 unique articles which were screened for title and abstract. Screening generated 12 articles which went through full-text analysis using eligibility criteria, and 4 articles were included for meta-analysis. Meta-analysis of these studies indicated a non-significant difference in the success rate between the two interventions (OR = 1.69 [0.74, 3.85; p = 0.21]). Bone loss estimates resulted in a significant bone reduction (Mean Difference = -0.74 [-0.95, -0.53; p - with two conventional-sized implants, the estimates were non-significant (Mean Difference = -0.24 [-0.69, 0.20; p = 0.29]). Conclusion: The current evidence does not provide solid evidence of the benefits of one intervention over the other. More studies with follow-up times of 10 and more years are needed as current studies have described the short-term outcomes.
背景:本荟萃分析的目的是评估一年随访后,与传统尺寸的植入物相比,小型植入物在植入成功率和平均骨丢失方面是否增加了益处。方法:在MEDLINE(通过PubMed)上进行随机临床试验的电子检索,Cochrane Central Register of Clinical Trials(Central)和Web of Science的研究,包括需要在上颌骨或下颌骨植入两个或四个迷你植入物或传统/标准尺寸植入物以用于植入物支持的可移除假体的完全或部分无牙患者,这些患者完成了12个月的随访。结果:搜索提供了194篇独特的文章,对其标题和摘要进行了筛选。筛选产生了12篇文章,这些文章使用资格标准进行了全文分析,4篇文章被纳入荟萃分析。这些研究的荟萃分析表明,两种干预措施的成功率无显著差异(OR=1.69[0.74,3.85;p=0.21])。骨丢失估计值导致了显著的骨减少(平均差异=0.74[-0.95,-0.53;p-对于两种常规尺寸的植入物,估计值无显著性(平均差异=-0.24[-0.69,0.20;p=0.29])。结论:目前的证据并不能提供一种干预措施相对于另一种干预的好处的确凿证据。由于目前的研究已经描述了短期结果,因此需要更多随访时间为10年或更长时间的研究。
{"title":"Comparison of Success Rate and Radiological Bone Loss in Patients with Mini-Implant versus Conventional-Sized Implant Removable Prostheses: A Meta-Analysis","authors":"Khaled Abubaker, Yuzhou Li, Sheng Yang","doi":"10.4236/OJST.2021.112006","DOIUrl":"https://doi.org/10.4236/OJST.2021.112006","url":null,"abstract":"Background: The objective of this meta-analysis was to assess whether mini-implants have added benefit in terms of implants success rate and average bone loss over conventional-sized implants after one year of follow-up. Methods: An electronic search of randomized clinical trials was conducted in MEDLINE (via PubMed), Cochrane Central Register of Clinical Trials (CENTRAL) and Web of Science for studies including complete or partial edentulous patients requiring two or four mini-implants or conventional/ standard-sized implants in the maxilla or mandible for implant-supported removable prostheses who completed 12 months of follow-up. Results: The search provided 194 unique articles which were screened for title and abstract. Screening generated 12 articles which went through full-text analysis using eligibility criteria, and 4 articles were included for meta-analysis. Meta-analysis of these studies indicated a non-significant difference in the success rate between the two interventions (OR = 1.69 [0.74, 3.85; p = 0.21]). Bone loss estimates resulted in a significant bone reduction (Mean Difference = -0.74 [-0.95, -0.53; p - with two conventional-sized implants, the estimates were non-significant (Mean Difference = -0.24 [-0.69, 0.20; p = 0.29]). Conclusion: The current evidence does not provide solid evidence of the benefits of one intervention over the other. More studies with follow-up times of 10 and more years are needed as current studies have described the short-term outcomes.","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48241581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
One-Step Multiplex PCR for Simultaneous Detection and Identification of Eight Medically Important Candida Species 一步多重PCR同时检测和鉴定8种重要的医学念珠菌
Pub Date : 2021-01-05 DOI: 10.4236/OJST.2021.111002
A. Fukatsu, O. Tsuzukibashi, Hidenori Suzuk, Katsuhiro Asaka, Yoshinori Ono, M. Fuchigami, Taira Kobayashi, Satoshi Uchibori, Yuji Takahashi, C. Komine, Y. Konishi, Y. Ogura, H. Omori, M. Wakami, H. Murakami, M. Fukumoto
Recently, the incidence of Candida infections has substantially increased. Conventional identification methods for Candida species are technically difficult to conduct and cannot accurately distinguish each species. The purpose of the present study was to design primers to identify and detect simultaneously eight medically important Candida species using one-step multiplex PCR. PCR primers were designed based on partial sequences of intergenic spacer (IGS) and internal transcribed spacer (ITS) genes of eight medically important Candida species. These primers were able to distinguish each Candida species and did not display cross-reactivity with representative Candida species other than the eight Candida species. Moreover, our developed one-step multiplex PCR method is accurate, specific, cost-effective, time-saving, and worked without requiring DNA extraction.
最近,念珠菌感染的发病率大幅上升。念珠菌物种的常规鉴定方法在技术上很难进行,并且不能准确区分每个物种。本研究的目的是设计引物,使用一步多重PCR同时鉴定和检测8种医学上重要的念珠菌。根据8种医学重要念珠菌的基因间间隔区(IGS)和内部转录间隔区(ITS)基因的部分序列设计了PCR引物。这些引物能够区分每种念珠菌,并且与除8种念珠菌以外的代表性念珠菌没有表现出交叉反应性。此外,我们开发的一步多重PCR方法准确、特异、经济高效、省时,而且不需要提取DNA。
{"title":"One-Step Multiplex PCR for Simultaneous Detection and Identification of Eight Medically Important Candida Species","authors":"A. Fukatsu, O. Tsuzukibashi, Hidenori Suzuk, Katsuhiro Asaka, Yoshinori Ono, M. Fuchigami, Taira Kobayashi, Satoshi Uchibori, Yuji Takahashi, C. Komine, Y. Konishi, Y. Ogura, H. Omori, M. Wakami, H. Murakami, M. Fukumoto","doi":"10.4236/OJST.2021.111002","DOIUrl":"https://doi.org/10.4236/OJST.2021.111002","url":null,"abstract":"Recently, the incidence of Candida infections has substantially increased. Conventional identification methods for Candida species are technically difficult to conduct and cannot accurately distinguish each species. The purpose of the present study was to design primers to identify and detect simultaneously eight medically important Candida species using one-step multiplex PCR. PCR primers were designed based on partial sequences of intergenic spacer (IGS) and internal transcribed spacer (ITS) genes of eight medically important Candida species. These primers were able to distinguish each Candida species and did not display cross-reactivity with representative Candida species other than the eight Candida species. Moreover, our developed one-step multiplex PCR method is accurate, specific, cost-effective, time-saving, and worked without requiring DNA extraction.","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42472262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Frequency and Factors Associated with Periodontitis in Congolese Patients: A Cross-Sectional Study 刚果患者牙周炎的发病频率和相关因素:一项横断面研究
Pub Date : 2021-01-05 DOI: 10.4236/OJST.2021.111005
Em Kalala-Kazadi, Fidèle Nyimi-Bushabu, Hubert Ntumba-Mulumba, M. Brecx
Background: Periodontitis is a multifactorial disease which is highly prevalent worldwide. The control of periodontal risk factor network is of paramount importance for the management of the disease. Aim: The aim of this study was to assess the frequency and identify the factors associated with periodontitis in Congolese patients. Material and Methods: This cross-sectional study was carried out in four medical centers in the city of Kinshasa between April 2017 and April 2018. The study included patients aged at least 12 years old who consulted the dental services of these centers and who met the inclusion criteria. The participants underwent a structured interview and a clinical periodontal examination. The latter involved the entire dentition, and periodontal pocket and attachment level measurements were taken at six sites per tooth. The plaque and bleeding index were recorded. Logistic regression was used to identify associated factors. The significance level was set at p 0.05. Results: The study included 827 patients and 42% of them had periodontitis. The most represented age group was between 20 and 29 years old. In multivariate analysis, age greater than or equal to 35 years, OR = 2.45 CI 95% (1.77 - 3.45), and the amount of plaque expressed as plaque index ≥ 1, OR = 2 CI 95% (1.31 - 3.07) were factors associated with periodontitis. Conclusion: Factors associated with periodontitis found in this study are age ≥35 years and the amount of plaque expressed as plaque index ≥ 1. The latter reveals the importance of good oral hygiene.
背景:牙周炎是一种多因素疾病,在世界范围内普遍存在。牙周危险因素网络的控制对疾病的管理至关重要。目的:本研究的目的是评估刚果患者牙周炎的发病率并确定与牙周炎相关的因素。材料和方法:这项横断面研究于2017年4月至2018年4月在金沙萨市的四个医疗中心进行。这项研究包括了至少12岁的患者,他们咨询了这些中心的牙科服务,并符合纳入标准。参与者接受了结构化访谈和临床牙周检查。后者涉及整个牙列,在每颗牙齿的六个部位进行牙周袋和附着水平测量。记录斑块和出血指数。Logistic回归用于确定相关因素。显著性水平设定为p 0.05。结果:该研究包括827名患者,其中42%患有牙周炎。最具代表性的年龄组在20至29岁之间。在多变量分析中,年龄大于或等于35岁,or=2.45 CI 95%(1.77-3.45),斑块数量表示为斑块指数≥1,or=2 CI 95%(1.31-3.07)是与牙周炎相关的因素。结论:本研究发现与牙周炎相关的因素是年龄≥35岁,斑块数量以斑块指数≥1表示。后者揭示了良好口腔卫生的重要性。
{"title":"Frequency and Factors Associated with Periodontitis in Congolese Patients: A Cross-Sectional Study","authors":"Em Kalala-Kazadi, Fidèle Nyimi-Bushabu, Hubert Ntumba-Mulumba, M. Brecx","doi":"10.4236/OJST.2021.111005","DOIUrl":"https://doi.org/10.4236/OJST.2021.111005","url":null,"abstract":"Background: Periodontitis is a multifactorial disease which is highly prevalent worldwide. The control of periodontal risk factor network is of paramount importance for the management of the disease. Aim: The aim of this study was to assess the frequency and identify the factors associated with periodontitis in Congolese patients. Material and Methods: This cross-sectional study was carried out in four medical centers in the city of Kinshasa between April 2017 and April 2018. The study included patients aged at least 12 years old who consulted the dental services of these centers and who met the inclusion criteria. The participants underwent a structured interview and a clinical periodontal examination. The latter involved the entire dentition, and periodontal pocket and attachment level measurements were taken at six sites per tooth. The plaque and bleeding index were recorded. Logistic regression was used to identify associated factors. The significance level was set at p 0.05. Results: The study included 827 patients and 42% of them had periodontitis. The most represented age group was between 20 and 29 years old. In multivariate analysis, age greater than or equal to 35 years, OR = 2.45 CI 95% (1.77 - 3.45), and the amount of plaque expressed as plaque index ≥ 1, OR = 2 CI 95% (1.31 - 3.07) were factors associated with periodontitis. Conclusion: Factors associated with periodontitis found in this study are age ≥35 years and the amount of plaque expressed as plaque index ≥ 1. The latter reveals the importance of good oral hygiene.","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43899084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Results of the Furlow’s Modified Technique in the Management of Cleft Palate in the Teaching Hospital of Conakry Furlow改良技术在科纳克里教学医院腭裂治疗中的效果评价
Pub Date : 2021-01-05 DOI: 10.4236/OJST.2021.111003
O. Diallo, A. Diallo, A. Conde, Thierno Abdourahmane Balde, Karamoko Alpha Diallo, G. Parker
Introduction: Cleft palate (CP) is a congenital dysmorphosis that results from a failure of the palatal processes of the maxillary buds and nasal septum to merge. The objectives of this study were to determine the frequency of complications of the modified Furlow technique and to evaluate its anatomical and functional outcomes. Materials and Method: This was a retrospective study that took place over a period of 4 years (from January 1st, 2015 to December 31th, 2018) in the Department of Odontostomatology and Maxillofacial Surgery at the National Hospital of Donka (Conakry, Guinea). Data retrieval consisted of records from patients operated on for cleft palate according to Furlow’s modified technique only. The operative technique consisted of marginal incisions of the cleft according to the technique of the double Z-plasty of Furlow. Subsequently, the defect created between the 2 flaps and the anterior edge of the cleft was filled by two fat masses of Bichat sutured to each other with Vicryl 3-0. Four years after surgery, the patients were recalled for an evaluation of the anatomical and functional results. Results: 13 patients underwent surgical loading according to the modified Furlow technique. The average age of the patients was 6.9 years with an age range of 7 months and 17 years. Females were the most affected, with 61.54% of cases and a sex ratio of 0.62. The primary repair rate was 84.61% of cases. Immediate operative follow-up was simple with epithelialization of the flaps in all patients. Four (4) years after the surgeries, 12 patients were reevaluated (92.30%), among them one case (8.33%) of fistula complication was noted. The mobility of the veil and the phonation were good in 85.71% and 60% respectively. Articular disorders with nasonation were found in 2 patients (16.67%). Swallowing was normal in 85.72% of cases. Conclusion: The modified Furlow technique is an important contribution to cleft palate surgery significantly reducing the occurrence of postoperative complications. However, the delay of the surgical operation remains a real obstacle for obtaining a normal phonation.
引言:腭裂(CP)是一种先天性畸形,由上颌芽和鼻中隔的腭突未能融合引起。本研究的目的是确定改良Furlow技术的并发症频率,并评估其解剖和功能结果。材料和方法:这是一项为期4年(从2015年1月1日至2018年12月31日)的回顾性研究,在顿卡国立医院(几内亚科纳克里)的口腔和颌面外科进行。数据检索仅包括根据Furlow改良技术进行腭裂手术的患者的记录。根据Furlow双Z形成形术的技术,手术技术包括腭裂的边缘切口。随后,用Vicryl 3-0缝合的两个Bichat脂肪块填充2个皮瓣和唇裂前缘之间形成的缺损。手术四年后,患者被召回,对解剖和功能结果进行评估。结果:13例患者按照改良的Furlow技术进行了手术负荷。患者的平均年龄为6.9岁,年龄范围为7个月和17岁。女性受影响最大,占61.54%,性别比为0.62。初次修复率为84.61%。所有患者的即时手术随访都很简单,皮瓣上皮化。术后四(4)年,对12名患者(92.30%)进行了重新评估,其中1例(8.33%)出现瘘管并发症。面纱的活动性和发声能力分别为85.71%和60%。2例(16.67%)患者出现关节紊乱伴鼻塞,85.72%的患者吞咽正常。结论:改良Furlow技术对腭裂手术显著减少术后并发症的发生有重要作用。然而,手术的延迟仍然是获得正常发音的真正障碍。
{"title":"Evaluation of Results of the Furlow’s Modified Technique in the Management of Cleft Palate in the Teaching Hospital of Conakry","authors":"O. Diallo, A. Diallo, A. Conde, Thierno Abdourahmane Balde, Karamoko Alpha Diallo, G. Parker","doi":"10.4236/OJST.2021.111003","DOIUrl":"https://doi.org/10.4236/OJST.2021.111003","url":null,"abstract":"Introduction: Cleft palate (CP) is a congenital dysmorphosis that results from a failure of the palatal processes of the maxillary buds and nasal septum to merge. The objectives of this study were to determine the frequency of complications of the modified Furlow technique and to evaluate its anatomical and functional outcomes. Materials and Method: This was a retrospective study that took place over a period of 4 years (from January 1st, 2015 to December 31th, 2018) in the Department of Odontostomatology and Maxillofacial Surgery at the National Hospital of Donka (Conakry, Guinea). Data retrieval consisted of records from patients operated on for cleft palate according to Furlow’s modified technique only. The operative technique consisted of marginal incisions of the cleft according to the technique of the double Z-plasty of Furlow. Subsequently, the defect created between the 2 flaps and the anterior edge of the cleft was filled by two fat masses of Bichat sutured to each other with Vicryl 3-0. Four years after surgery, the patients were recalled for an evaluation of the anatomical and functional results. Results: 13 patients underwent surgical loading according to the modified Furlow technique. The average age of the patients was 6.9 years with an age range of 7 months and 17 years. Females were the most affected, with 61.54% of cases and a sex ratio of 0.62. The primary repair rate was 84.61% of cases. Immediate operative follow-up was simple with epithelialization of the flaps in all patients. Four (4) years after the surgeries, 12 patients were reevaluated (92.30%), among them one case (8.33%) of fistula complication was noted. The mobility of the veil and the phonation were good in 85.71% and 60% respectively. Articular disorders with nasonation were found in 2 patients (16.67%). Swallowing was normal in 85.72% of cases. Conclusion: The modified Furlow technique is an important contribution to cleft palate surgery significantly reducing the occurrence of postoperative complications. However, the delay of the surgical operation remains a real obstacle for obtaining a normal phonation.","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49138035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Loss of Masticatory Function Affects Morphology of the Tooth Root in Rats 咀嚼功能丧失对大鼠牙根形态的影响
Pub Date : 2021-01-05 DOI: 10.4236/OJST.2021.111004
Takamichi Yamada, Kei Ogawa, Takehiko Shimizu
Masticatory hypofunction and soft food affect the tooth rows, occlusion, and jawbone. This study aimed to clarify the influence of tooth loss and a soft diet on morphology of the tooth root during the growth period. We divided 3-week-old Wistar rats into the following three groups: Hard diet group (rats raised on solid standard diet), Powder diet group (rats raised on powdered standard feed diet), and Extraction group (rats raised on powdered standard diet with maxillary molars extraction). Length, width, cross-sectional area, and volume of the root of the mandibular M1 and M2 were measured using micro-CT analysis. Non-decalcified thin-slice specimens of sagittal sections of the M1 were obtained at the age of 20 weeks, and the roots were observed. The root length of all roots in the Extraction group was significantly longer than that in the other groups. The root width and cross-sectional area at the apical side 1/4 of all roots in the Extraction group were significantly smaller than those in the other groups. The root volume of the M1 mesial root in the Extraction group was significantly smaller than that in the other groups. This study clarified that when masticatory stimulus in the immature teeth is reduced by the extraction of opposing teeth and a powder diet, the root length increases due to the promotion of cellular cementum addition at the apex, and the root width and cross-sectional area decrease due to the suppression of cellular cementum addition at the apical side 1/4 of the roots.
咀嚼功能减退和软性食物会影响牙齿排列、咬合和颚骨。本研究旨在阐明生长期牙齿脱落和软性饮食对牙根形态的影响。我们将3周大的Wistar大鼠分为以下三组:硬食组(在固体标准饮食中饲养的大鼠)、粉末饮食组(在粉末标准饲料中饲养的小鼠)和提取组(在带有上颌磨牙提取的粉末标准饮食中养大鼠)。使用显微CT分析测量下颌M1和M2根部的长度、宽度、截面积和体积。在20周龄时获得M1矢状切面的非脱钙薄片标本,并观察根部。提取组所有根的根长均显著长于其他组。提取组的根宽度和根尖侧横截面积为所有根的1/4,显著小于其他组。提取组M1近中根的根体积明显小于其他组。本研究阐明,当通过拔除对牙和粉末饮食减少未成熟牙齿的咀嚼刺激时,由于促进根尖细胞牙骨质的添加,牙根长度增加,而由于抑制根尖侧1/4细胞牙骨质添加,牙根宽度和横截面积减少。
{"title":"Loss of Masticatory Function Affects Morphology of the Tooth Root in Rats","authors":"Takamichi Yamada, Kei Ogawa, Takehiko Shimizu","doi":"10.4236/OJST.2021.111004","DOIUrl":"https://doi.org/10.4236/OJST.2021.111004","url":null,"abstract":"Masticatory hypofunction and soft food affect the tooth rows, occlusion, and jawbone. This study aimed to clarify the influence of tooth loss and a soft diet on morphology of the tooth root during the growth period. We divided 3-week-old Wistar rats into the following three groups: Hard diet group (rats raised on solid standard diet), Powder diet group (rats raised on powdered standard feed diet), and Extraction group (rats raised on powdered standard diet with maxillary molars extraction). Length, width, cross-sectional area, and volume of the root of the mandibular M1 and M2 were measured using micro-CT analysis. Non-decalcified thin-slice specimens of sagittal sections of the M1 were obtained at the age of 20 weeks, and the roots were observed. The root length of all roots in the Extraction group was significantly longer than that in the other groups. The root width and cross-sectional area at the apical side 1/4 of all roots in the Extraction group were significantly smaller than those in the other groups. The root volume of the M1 mesial root in the Extraction group was significantly smaller than that in the other groups. This study clarified that when masticatory stimulus in the immature teeth is reduced by the extraction of opposing teeth and a powder diet, the root length increases due to the promotion of cellular cementum addition at the apex, and the root width and cross-sectional area decrease due to the suppression of cellular cementum addition at the apical side 1/4 of the roots.","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43535300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health Indicator Bacteria That Is Useful for Risk Assessment of Peri-Implantitis 对种植体周围炎风险评估有用的健康指示菌
Pub Date : 2021-01-01 DOI: 10.4236/ojst.2021.119032
Hidenori Suzuki, O. Tsuzukibashi, A. Fukatsu
We established a novel identification method for oral Rothia species using one-step multiplex PCR analysis to investigate whether the monitoring of oral Rothia species levels is useful for peri-implantitis risk assessment, and to examine the oxygen concentration that these organisms need for growth in vitro. The mean number and proportion of Rothia aeria in peri-implant sulcus fluid (PISF) samples was significantly higher in the healthy implant group than in the peri-implantitis group (P < 0.05). Moreover, R. aeria under aerobic conditions vigorously grew compared with those under anaerobic conditions, and this organism grew only at the upper layer where high oxygen concentrations existed in a semi-liquid nutrient medium. Therefore, the monitoring of R. aeria levels may be suitable as an indicator of healthy peri-implant tissue conditions for the prevention of peri-implantitis.
我们建立了一种新的口服罗氏菌的鉴定方法,采用一步多重PCR分析方法来研究监测口服罗氏菌的水平是否有助于评估种植体周围炎的风险,并检测这些生物在体外生长所需的氧浓度。健康种植体组种植体周围沟液(PISF)标本中罗氏菌的平均数量和比例显著高于种植体周围炎组(P < 0.05)。此外,好氧条件下的R. aeria比厌氧条件下的R. aeria生长旺盛,且该生物仅在高氧浓度的半液态营养培养基上层生长。因此,监测aeria水平可能适合作为健康种植体周围组织状况的指标,以预防种植体周围炎。
{"title":"Health Indicator Bacteria That Is Useful for Risk Assessment of Peri-Implantitis","authors":"Hidenori Suzuki, O. Tsuzukibashi, A. Fukatsu","doi":"10.4236/ojst.2021.119032","DOIUrl":"https://doi.org/10.4236/ojst.2021.119032","url":null,"abstract":"We established a novel identification method for oral Rothia species using one-step multiplex PCR analysis to investigate whether the monitoring of oral Rothia species levels is useful for peri-implantitis risk assessment, and to examine the oxygen concentration that these organisms need for growth in vitro. The mean number and proportion of Rothia aeria in peri-implant sulcus fluid (PISF) samples was significantly higher in the healthy implant group than in the peri-implantitis group (P < 0.05). Moreover, R. aeria under aerobic conditions vigorously grew compared with those under anaerobic conditions, and this organism grew only at the upper layer where high oxygen concentrations existed in a semi-liquid nutrient medium. Therefore, the monitoring of R. aeria levels may be suitable as an indicator of healthy peri-implant tissue conditions for the prevention of peri-implantitis.","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70658878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Oral Lesions Observed in Tobacco Consumers: Socio-Demographical and Clinical Aspects in the Prefectures of Kankan and Siguiri Republic of Guinea 烟草消费者中观察到的口腔病变:几内亚坎坎和锡吉里共和国县的社会人口统计学和临床方面
Pub Date : 2021-01-01 DOI: 10.4236/ojst.2021.1111039
Diallo Oumar Raphiou, Conde Alhassane, Diallo Ibrahim, Baldé Mamadou Aliou
Introduction: Oral lesions observed in Chewing Tobacco (CT) consumers are histological alterations caused by direct contact with the tissues of the oral cavity. The objectives of this study were to determine the socio-demographic status of consumers and describe the clinical characteristics of the oral lesions observed. Material and Method: It was a descriptive cross-sectional study last-ing 12 months (January 2017 to January 2018), in the prefectures of Kankan and Siguiri as a framework. Individuals who use chewing tobacco and whose oral examination revealed oral lesions were included in this study. Results: The frequency of oral lesions induced by the consumption of chewing tobacco was 90%. Dental pain was the most cited reason for using CT by respondents, i.e., 25.41%. The most concerned age group was that of 50 - 64 years or 23.81 with a male predominance of 84.13% (n = 53). A number of 61 respondents came from rural areas. Farmers were the predominant socio-professional group, i.e., 63.49% (n = 40). In 60.32% (n = 38) of respondents, the duration of CT consumption was greater than 10 years. Black villous tongues followed by neoplastic ulcerations were the most common oral lesions with 32 (50.79%) and 14 (22.22%) cases, respectively. The site of the lesion was the tongue
在咀嚼烟草(CT)消费者中观察到的口腔病变是由直接接触口腔组织引起的组织学改变。本研究的目的是确定消费者的社会人口状况,并描述观察到的口腔病变的临床特征。材料和方法:这是一项为期12个月(2017年1月至2018年1月)的描述性横断面研究,以Kankan县和Siguiri县为框架。使用咀嚼烟草和口腔检查发现口腔病变的个体包括在这项研究中。结果:咀嚼烟草致口腔病变发生率为90%。牙痛是受访者使用CT的最主要原因,占25.41%。50 ~ 64岁(23.81)为最关注年龄组,男性占84.13% (n = 53)。61名受访者来自农村地区。农民是主要的社会专业群体,占63.49% (n = 40)。60.32% (n = 38)的受访者使用CT时间超过10年。以黑色绒毛舌和肿瘤性溃疡次之,分别为32例(50.79%)和14例(22.22%)。患处在舌头上
{"title":"Oral Lesions Observed in Tobacco Consumers: Socio-Demographical and Clinical Aspects in the Prefectures of Kankan and Siguiri Republic of Guinea","authors":"Diallo Oumar Raphiou, Conde Alhassane, Diallo Ibrahim, Baldé Mamadou Aliou","doi":"10.4236/ojst.2021.1111039","DOIUrl":"https://doi.org/10.4236/ojst.2021.1111039","url":null,"abstract":"Introduction: Oral lesions observed in Chewing Tobacco (CT) consumers are histological alterations caused by direct contact with the tissues of the oral cavity. The objectives of this study were to determine the socio-demographic status of consumers and describe the clinical characteristics of the oral lesions observed. Material and Method: It was a descriptive cross-sectional study last-ing 12 months (January 2017 to January 2018), in the prefectures of Kankan and Siguiri as a framework. Individuals who use chewing tobacco and whose oral examination revealed oral lesions were included in this study. Results: The frequency of oral lesions induced by the consumption of chewing tobacco was 90%. Dental pain was the most cited reason for using CT by respondents, i.e., 25.41%. The most concerned age group was that of 50 - 64 years or 23.81 with a male predominance of 84.13% (n = 53). A number of 61 respondents came from rural areas. Farmers were the predominant socio-professional group, i.e., 63.49% (n = 40). In 60.32% (n = 38) of respondents, the duration of CT consumption was greater than 10 years. Black villous tongues followed by neoplastic ulcerations were the most common oral lesions with 32 (50.79%) and 14 (22.22%) cases, respectively. The site of the lesion was the tongue","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70658869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Etiology of Pediatric Maxillofacial Fractures in a Group of Yemeni Children and Adolescents 一组也门儿童和青少年儿童颌面骨折的患病率和病因学
Pub Date : 2021-01-01 DOI: 10.4236/OJST.2021.115015
N. Al-Tairi, Jabr Atiq Al-Radom
Although maxillofacial fractures are not as common in children as in adults, trauma is still the leading cause of morbidity and mortality in the pediatric population worldwide. The aim of this study was to review the pattern and prevalence of pediatric maxillofacial fractures in a sample of the Yemeni population aged 18 years and below. A retrospective analysis of patient records and radiographs was conducted for the 4 year period between June 2016 and October 2020. A total of 71 patients had 87 fractures divided into three age groups, i.e., preschool group (0 - 6 years), primary school group (7 - 12 years) and teenage group (13 - 18 years). The male to female ratio was 2.38:1 and the highest incidence occurred in the age group 13 to 18 years. The main etiological factor was road traffic accidents (RTA), however, falls were the primary etiology in the preschool age group. We conclude that maxillofacial trauma in pediatric patients is associated mainly with RTA and fall and; the mandible is more affected than other maxillofacial structures with the condyle being the most frequently fractured mandibular site.
虽然颌面骨折在儿童中不像在成人中那么常见,创伤仍然是世界范围内儿童发病率和死亡率的主要原因。本研究的目的是回顾也门18岁及以下儿童颌面骨折的模式和患病率。对2016年6月至2020年10月期间的患者记录和x线片进行了回顾性分析。71例患者共发生骨折87例,分为3个年龄组,即学龄前组(0 ~ 6岁)、小学组(7 ~ 12岁)和青少年组(13 ~ 18岁)。男女比例为2.38:1,以13 ~ 18岁年龄组发病率最高。主要病因是道路交通事故(RTA),但跌倒是学龄前儿童的主要病因。我们得出结论,儿科患者的颌面外伤主要与RTA和跌倒有关;下颌骨比其他颌面结构更容易受到影响,髁突是最常见的下颌骨折部位。
{"title":"Prevalence and Etiology of Pediatric Maxillofacial Fractures in a Group of Yemeni Children and Adolescents","authors":"N. Al-Tairi, Jabr Atiq Al-Radom","doi":"10.4236/OJST.2021.115015","DOIUrl":"https://doi.org/10.4236/OJST.2021.115015","url":null,"abstract":"Although maxillofacial fractures are not as common in children as in adults, trauma is still the leading cause of morbidity and mortality in the pediatric population worldwide. The aim of this study was to review the pattern and prevalence of pediatric maxillofacial fractures in a sample of the Yemeni population aged 18 years and below. A retrospective analysis of patient records and radiographs was conducted for the 4 year period between June 2016 and October 2020. A total of 71 patients had 87 fractures divided into three age groups, i.e., preschool group (0 - 6 years), primary school group (7 - 12 years) and teenage group (13 - 18 years). The male to female ratio was 2.38:1 and the highest incidence occurred in the age group 13 to 18 years. The main etiological factor was road traffic accidents (RTA), however, falls were the primary etiology in the preschool age group. We conclude that maxillofacial trauma in pediatric patients is associated mainly with RTA and fall and; the mandible is more affected than other maxillofacial structures with the condyle being the most frequently fractured mandibular site.","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70659065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Disparities in Oral Healthcare Access Due to the COVID-19 Pandemic COVID-19大流行导致的口腔卫生保健可及性差异
Pub Date : 2021-01-01 DOI: 10.4236/ojst.2021.1111038
Fnu Namrata, Z. Loewy
The U.S. has experienced very high numbers of positive COVID-19 cases, along with high unemployment rates during the COVID-19 pandemic. Simi-larly, on a global level, the pandemic has resulted in an increase in the unemployment rate, loss of insurance and an overall adverse social impact. In the social sector, there has been a huge gap in supply and demand; this has been especially apparent in the healthcare industry. The COVID-19 pandemic has had a significant negative impact on high-contact industries, including denti-stry. Causative factors have included social distancing, shortage of healthcare professionals and loss of insurance due to unemployment. The result has been a void in preventative oral health services. Limited information on the disproportionate access to oral healthcare, due to the increase in unemployment and corresponding loss of insurance during the COVID-19 pandemic is availa-ble. This study was designed to investigate the disparities in access to oral healthcare amidst the global economic crisis and rise in unemployment.
在COVID-19大流行期间,美国的COVID-19阳性病例数量非常高,失业率也很高。同样,在全球一级,这一流行病造成失业率上升、丧失保险和总体不利的社会影响。在社会领域,存在着巨大的供需缺口;这一点在医疗保健行业尤为明显。COVID-19大流行对包括牙科在内的高接触行业产生了重大负面影响。致病因素包括社交距离、医疗保健专业人员短缺以及因失业而失去保险。其结果是预防性口腔保健服务的空白。在2019冠状病毒病大流行期间,由于失业增加和相应的保险损失,获得口腔保健的机会不成比例,目前的信息有限。本研究旨在探讨在全球经济危机和失业率上升的情况下,口腔保健服务的可及性差异。
{"title":"Disparities in Oral Healthcare Access Due to the COVID-19 Pandemic","authors":"Fnu Namrata, Z. Loewy","doi":"10.4236/ojst.2021.1111038","DOIUrl":"https://doi.org/10.4236/ojst.2021.1111038","url":null,"abstract":"The U.S. has experienced very high numbers of positive COVID-19 cases, along with high unemployment rates during the COVID-19 pandemic. Simi-larly, on a global level, the pandemic has resulted in an increase in the unemployment rate, loss of insurance and an overall adverse social impact. In the social sector, there has been a huge gap in supply and demand; this has been especially apparent in the healthcare industry. The COVID-19 pandemic has had a significant negative impact on high-contact industries, including denti-stry. Causative factors have included social distancing, shortage of healthcare professionals and loss of insurance due to unemployment. The result has been a void in preventative oral health services. Limited information on the disproportionate access to oral healthcare, due to the increase in unemployment and corresponding loss of insurance during the COVID-19 pandemic is availa-ble. This study was designed to investigate the disparities in access to oral healthcare amidst the global economic crisis and rise in unemployment.","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70658855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Labio-Jugal Squamous Cell Carcinoma on HIV Site: Surgical Excision and Reconstruction with a Musculocutaneous Flap of the Pectoralis Major: A Case Report 唇-下颌鳞状细胞癌在HIV部位:手术切除和重建与胸大肌肌皮瓣:1例报告
Pub Date : 2021-01-01 DOI: 10.4236/ojst.2021.1111041
S. Adam, H. Sama, E. Pegbessou, Yao Messanvi Akpoto, P. Agoda, W. Foma, Haréfétéguéna Bissa, B. Amana, M. Djibril, E. Boko, E. Kpemissi
Introduction: Malignant skin tumors are very frequent lesions, induced by sustained sun exposure. Cutaneous squamous cell carcinoma is a dangerous cancer of the skin. It’s more frequent in white people than black people. Squamous cell carcinomas sometimes pose a real problem of local reconstruction after their removal. Reconstructions may involve the production of regional pe-dunculated flaps to repair the loss of substance. We report the case of a la-bio-jugal squamous cell carcinoma in an HIV-positive patient. The excision of the tumor required repair by a CT scan did not note any regional tumor invasion. We indicated tumor excision, functional lymph node dissection, and reconstruction by a flap of the pectoralis major muscle. The operative procedure was performed under general anesthesia. The edge cuts after carcinoma removal were healthy. Three months later, the patient is seen again with a local right submandibular recurrence. Radiotherapy was offered to him. Discussion: Squamous cell carcinomas are frequent in sub-Saharan Africa with preferential localization to oropharynx and oral cavity. More and more viral infections such as HIV, HBV and HCV are implicated in the occurrence of squamous cell carcinomas of the ENT and neck and facial sphere. HIV appears to be a contributing factor in young populations. Multidisciplinary management with anti-infective treatment coupled with new therapies could reduce the risk of recurrence and me-tastases.
简介:恶性皮肤肿瘤是非常常见的病变,由持续的阳光照射引起。皮肤鳞状细胞癌是一种危险的皮肤癌症。它在白人中比黑人更常见。鳞状细胞癌在切除后有时会造成局部重建的问题。重建可能涉及到局部带孔皮瓣的生产,以修复物质的损失。我们报告的情况下,一个生物法律鳞状细胞癌在艾滋病毒阳性患者。需要通过CT扫描修复的肿瘤切除未发现任何区域肿瘤侵袭。我们建议切除肿瘤,功能性淋巴结清扫,并用胸大肌瓣重建。手术在全身麻醉下进行。癌切除后边缘切口健康。三个月后,患者再次出现局部右下颌下复发。他接受了放射治疗。讨论:鳞状细胞癌常见于撒哈拉以南非洲,优先定位于口咽和口腔。越来越多的病毒感染,如HIV、HBV和HCV与耳鼻喉、颈部和面部鳞状细胞癌的发生有关。艾滋病毒似乎是年轻人群中的一个促成因素。多学科管理与抗感染治疗相结合的新疗法可以降低复发和复发的风险。
{"title":"Labio-Jugal Squamous Cell Carcinoma on HIV Site: Surgical Excision and Reconstruction with a Musculocutaneous Flap of the Pectoralis Major: A Case Report","authors":"S. Adam, H. Sama, E. Pegbessou, Yao Messanvi Akpoto, P. Agoda, W. Foma, Haréfétéguéna Bissa, B. Amana, M. Djibril, E. Boko, E. Kpemissi","doi":"10.4236/ojst.2021.1111041","DOIUrl":"https://doi.org/10.4236/ojst.2021.1111041","url":null,"abstract":"Introduction: Malignant skin tumors are very frequent lesions, induced by sustained sun exposure. Cutaneous squamous cell carcinoma is a dangerous cancer of the skin. It’s more frequent in white people than black people. Squamous cell carcinomas sometimes pose a real problem of local reconstruction after their removal. Reconstructions may involve the production of regional pe-dunculated flaps to repair the loss of substance. We report the case of a la-bio-jugal squamous cell carcinoma in an HIV-positive patient. The excision of the tumor required repair by a CT scan did not note any regional tumor invasion. We indicated tumor excision, functional lymph node dissection, and reconstruction by a flap of the pectoralis major muscle. The operative procedure was performed under general anesthesia. The edge cuts after carcinoma removal were healthy. Three months later, the patient is seen again with a local right submandibular recurrence. Radiotherapy was offered to him. Discussion: Squamous cell carcinomas are frequent in sub-Saharan Africa with preferential localization to oropharynx and oral cavity. More and more viral infections such as HIV, HBV and HCV are implicated in the occurrence of squamous cell carcinomas of the ENT and neck and facial sphere. HIV appears to be a contributing factor in young populations. Multidisciplinary management with anti-infective treatment coupled with new therapies could reduce the risk of recurrence and me-tastases.","PeriodicalId":56569,"journal":{"name":"口腔学期刊(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70658943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
口腔学期刊(英文)
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1