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Study of the Impact of the Patient Rhythm during Cryoballoon Ablation on the Acute Biophysical Parameters 低温球囊消融过程中患者心律对急性生物物理参数影响的研究
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.121007
Mohamed Sanhoury, G. Fassini, Salvatore Pala, M. Moltrasio, F. Tundo, S. Riva, A. Russo, M. Casella, C. Tondo
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引用次数: 0
Complications of Peripartum Cardiomyopathy at the Departmental University Hospital Teaching of Borgou (Benin) in 2022: About 3 Cases 2022年贝宁博古大学附属医院教学围生期心肌病并发症约3例
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.1211053
L. Codjo, S. Dohou, Sèdjro Raoul Atadé, F. Atika, H. N. Amegan, C. Biaou, K. M. Hounkponou, D. Sonou, M. P. Adjagba, M. D. Soude, Dominique Sacca, Mèdéssè Rolande Quenum, Aude Sourou Bodjrenou, M. Houénassi
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引用次数: 0
An Unusual Presentation of Aortic Dissection and Aneurysmatic Disease in Marfan Syndrome: A Case Report 马凡氏综合征的主动脉夹层和动脉瘤疾病的不寻常表现:1例报告
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.126029
Adrian Espejel-Guzman, Valente Fernandez-Badillo, Javier Serrano-Roman, Enrique Solorzano-Pinot, S. Críales-Vera, María Del Carmen Lopez-Rodríguez, C. Keirns, Daniel Zagal-Cardoso, N. Espinola-Zavaleta
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引用次数: 0
Long-Term Prognosis and Predictive Risk Factors for Polyvascular Disease in Patients with Peripheral Arterial Disease 外周动脉疾病患者多血管疾病的长期预后及预测危险因素
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.121006
K. Nakashima, H. Kumakura, R. Funada, Yae Matsuo, Kimimasa Sakata, Akiko Ichikawa, T. Iwasaki, S. Ichikawa
Background: The aim of the current study was to assess fifteen-year life expectancy, cardiovascular events, fate of the limb, and risk factors with or without polyvascular disease in patients with Peripheral Arterial Disease (PAD). Methods: We conducted a prospective cohort study in 1019 PAD patients. The endpoints were Cardiovascular or Cerebrovascular Death (CCVD), All-Cause Death (ACD), Major Adverse Cardiovascular Events (MACE), and Cardiovascular and/or Limb Events (CVLE). Results: The patients who died were 539 (52.9%) during follow-up periods. The rate of CCVD was 50.5% (n = 272). In multiple regression analysis, the number of affected arteries had correlations with estimated Glomerular Filtration Rate (eGFR), HDL-cholesterol, Ankle Brachial Pressure Index (ABI), and diabetes (p < 0.05). In multiple logistic analysis, PAD with Cerebrovascular Disease (CVD) was cor related with older age, ABI, eGFR, and atrial fibrillation (p < 0.05); to CVLE (p < 0.05). Statins improved all outcomes (p < 0.05). Conclusions: Polyvascular disease was independently associated with fifteen-year mortality, cardiovascular events, and the fate of the limb with diverse risk factors in PAD patients.
背景:本研究的目的是评估外周动脉疾病(PAD)患者的15年预期寿命、心血管事件、肢体命运和伴有或不伴有多血管疾病的危险因素。方法:我们对1019例PAD患者进行了前瞻性队列研究。终点是心脑血管死亡(CCVD)、全因死亡(ACD)、主要不良心血管事件(MACE)和心血管和/或肢体事件(CVLE)。结果:随访期间死亡539例(52.9%)。CCVD发生率为50.5% (n = 272)。在多元回归分析中,受影响动脉数量与肾小球滤过率(Glomerular Filtration Rate, eGFR)、高密度脂蛋白胆固醇(HDL-cholesterol)、踝肱压指数(Ankle Brachial Pressure Index, ABI)和糖尿病相关(p < 0.05)。多因素logistic分析显示,PAD合并脑血管病(CVD)与年龄、ABI、eGFR、房颤相关(p < 0.05);与CVLE比较(p < 0.05)。他汀类药物改善了所有结果(p < 0.05)。结论:多血管疾病与PAD患者15年死亡率、心血管事件和具有多种危险因素的肢体命运独立相关。
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引用次数: 0
Marfan Syndrome Complicated by Aortic Arch Aneurysm and Aortic Dissection: A Case Report from Congo 马凡氏综合征并发主动脉弓动脉瘤和主动脉夹层:刚果1例报告
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.1210048
Solange Flore Ngamami Mongo, B. E. Mbolla, Franck Yannis Kouikani, Kivié Mou-Moué Ngolo Letomo, R. Bakekolo, C. K. Landa
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引用次数: 0
Cardio-Renal Syndrome: Epidemiological Aspect in the Medicine Department of Tombouctou Hospital 心肾综合征:汤布头医院内科的流行病学研究
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.122013
B. Traoré, S. Sidibé, Souleymane Mariko, Karamoko Kantako, M. Konaté, Kalifa Diallo, N. Diallo, M. Sako, A. K. Sacko, Y. Kassambara, I. Menta, S. Coulibaly
{"title":"Cardio-Renal Syndrome: Epidemiological Aspect in the Medicine Department of Tombouctou Hospital","authors":"B. Traoré, S. Sidibé, Souleymane Mariko, Karamoko Kantako, M. Konaté, Kalifa Diallo, N. Diallo, M. Sako, A. K. Sacko, Y. Kassambara, I. Menta, S. Coulibaly","doi":"10.4236/wjcd.2022.122013","DOIUrl":"https://doi.org/10.4236/wjcd.2022.122013","url":null,"abstract":"","PeriodicalId":67027,"journal":{"name":"心血管病(英文)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70869868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FACE-HF: Focused Assessment by Chest Sonography and Echocardiography in Acute Heart Failure Patients FACE-HF:急性心力衰竭患者的胸部超声和超声心动图集中评估
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.123015
Mohamed Sanhoury, S. Elsayed, A. Almaghraby, M. Hassanein, A. Alkafafy
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引用次数: 0
Risk Factors for Mortality of Patients Waiting for Elective Coronary Artery Bypass Graft Surgery 等待择期冠状动脉搭桥手术患者死亡的危险因素
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.126030
Adymas Perdana, M. A. Nugroho, S. Suhartono, M. A. Sobirin
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引用次数: 0
A Rare Case of Improved Mitral Regurgitation after the Inter-Atrial Septal Defect Created during an Unsuccessful Percutaneous Mitra-Clip Placement Attempt 一例罕见的经皮二尖瓣夹置入失败的房间隔缺损后二尖瓣返流改善的病例
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.127035
D. Kumanayaka, Zaid Amin, Ahsan Khan, Addi Suleiman
Percutaneous mitral valve repair has shown to be a less-invasive treatment option for patients with symptomatic severe mitral regurgitation (MR) with multiple comorbidities. We describe a case of improved mitral regurgitation due to improved atrial fibrillation secondary to left atrial pressure relief after the inter-atrial defect created during an unsuccessful mitraclip placement attempt. Transthoracic Echocardiogram that was performed on admission showed severe mitral valve regurgitation. She was not a surgical candidate due to multiple co-morbidities. Patient was then medically optimized and a percutaneous MitraClip placement (PMCP) was attempted but was unsuccessful due to excessive trans-mitral gradient and the procedure was aborted. How-ever, left atrial pressure decreased, likely secondary to inter-atrial septal defect created by the procedure. Transesophageal echocardiogram performed post-op showed moderate and improved mitral regurgitation and sinus rhythm. Attempts to convert atrial fibrillation to sinus rhythm to improve mitral regurgitation had to be made before continuing with a mitral clip placement procedure in our case. In our case, the procedure itself did not help patient’s symptoms, but the resulting acute atrial pressure relief improved mitral regurgitation overall due to left to right shunt from iASD, which also helped the rhythm.
经皮二尖瓣修复已被证明是一种侵入性较小的治疗选择,患者的症状严重二尖瓣反流(MR)有多种合并症。我们描述了一个改善二尖瓣反流的情况下,由于改善心房颤动继发于左心房压力缓解后,在一个不成功的二尖瓣置入尝试心房缺损。入院时经胸超声心动图显示严重的二尖瓣返流。由于多重合并症,她不适合手术。然后对患者进行医学优化,并尝试经皮二尖瓣植入(PMCP),但由于二尖瓣间梯度过大而失败,手术流产。然而,左房压下降,可能继发于手术造成的房间隔缺损。术后经食管超声心动图显示中度和改善二尖瓣反流和窦性心律。在我们的病例中,在继续二尖瓣夹放置手术之前,必须尝试将心房颤动转化为窦性心律以改善二尖瓣反流。在我们的病例中,手术本身并没有改善患者的症状,但由此产生的急性心房压力缓解总体上改善了二尖瓣反流,这是由于从iASD向左向右分流,这也有助于心律。
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引用次数: 0
Contribution of Myocyte Apoptosis to Myocardial Injury in an in Vivo Rabbit Preparation of Ischemia-Reperfusion 兔体内缺血再灌注制备中心肌细胞凋亡对心肌损伤的贡献
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.128044
J. Kingma
Objective: Exposure of the heart to repeated, brief episodes of coronary oc-clusion/reperfusion prevents lethal myocyte injury. Necrosis and apoptosis, two seemingly distinct mechanisms of cell death caused by ischemia could contribute independently to progressive loss of myocardium. Studies suggest that ischemic conditioning (IC) lessens myocyte injury by decreasing apoptosis. The goal of this study was to examine cell death in rabbit hearts subject to ischemia-reperfusion injury without (nIC) or with pretreatment by IC. Methods: In the control study, anesthetized, male rabbits (n = 4/group) un-derwent 30-min regional coronary occlusion (CO) and either 3, 6 or 24 h reperfusion (REP). In the IC study, rabbits were pretreated by IC (2 cycles of 5-min CO and 10-min REP) before 30-min CO and subsequent REP. Addi-tional groups were evaluated with 60, or 120-min CO followed by up to 96 h REP. Agarose electrophoresis was used to detect DNA laddering and poly (ADP-ribose) polymerase (PARP; chromatin bound nuclear DNA repair enzyme) was assessed in myocardial biopsies. Results: Genomic DNA from nIC and IC hearts showed no oligonucleosomal fragmentation. In addition, we did not detect any cleavage of PARP; however, myocardial PARP levels decreased when CO and REP durations were prolonged. Conclusion: Absence of genomic DNA fragmentation or PARP cleavage in an in vivo preparation of ischemia-reperfusion injury does not support the view that apoptosis contributes markedly to post-ischemic tissue necrosis.
目的:心脏暴露于反复、短暂的冠状动脉闭塞/再灌注可预防致死性心肌细胞损伤。坏死和凋亡是缺血引起的两种不同的细胞死亡机制,可以独立地促进心肌的进行性损失。研究表明,缺血调节(IC)通过减少细胞凋亡来减轻肌细胞损伤。本研究的目的是观察兔心脏缺血再灌注损伤后的细胞死亡情况。方法:在对照研究中,麻醉的雄性兔(n = 4/组)进行30分钟的局部冠状动脉闭塞(CO)和3、6或24小时的再灌注(REP)。在IC研究中,兔在30分钟CO和随后的REP前进行IC预处理(2个循环5分钟CO和10分钟REP),另外两组分别在60分钟或120分钟CO和96小时REP后进行评估。琼脂糖电泳检测DNA阶梯和聚(adp -核糖)聚合酶(PARP);在心肌活组织检查中评估染色质结合核DNA修复酶。结果:nIC和IC心脏的基因组DNA未出现寡核体断裂。此外,我们没有检测到PARP的任何切割;然而,心肌PARP水平随着CO和REP持续时间的延长而下降。结论:在缺血-再灌注损伤的体内制备中,基因组DNA片段或PARP切割缺失并不支持细胞凋亡对缺血后组织坏死有显著作用的观点。
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引用次数: 1
期刊
心血管病(英文)
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