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心血管病(英文)最新文献

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Venous Thromboembolic Disease in the Cardiology Department of the Nianakoro Fomba Hospital in Segou (HNF) 塞古市Nianakoro formba医院心内科静脉血栓栓塞性疾病(HNF)
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.1211052
M. Sako, M. Touré, Boureima Dembélé, Y. R. Koumaré, M. Konaté, M. Diakité, C. Thiam, A. Kodio, S. Sidibé, A. Keita, Aichata Dao, Y. Camara, B. Sonfo, B. Traoré, Souleymane Mariko, S. Coulibaly, I. Menta
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引用次数: 0
Preventing Heart Disease via Coronary Artery Calcium Scoring to Make a Definitive Diagnosis of Atherosclerosis 通过冠状动脉钙化评分预防心脏病以明确诊断动脉粥样硬化
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.1210047
D. Schade, S. Wann, Martin Hickey, S. Obenshain, Jennifer A Febbo, R. Eaton
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引用次数: 0
Asymptomatic Mitral Regurgitation Caused by an Isolated Mitral Leaflet Cleft in a Young Adult: A Case Report 年轻成人孤立二尖瓣小叶裂致无症状二尖瓣返流1例报告
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.122012
M. Leye, S. Beye, M. Dioum, Sarah Mouna Coly, D. A. Affangla, D. Ba, F. Aw, Khadidiatou Guèye, S. Akani, M. Ndiaye
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引用次数: 0
Determinants of Blood Pressure Variability in Individuals with Essential Hypertension: A Survey-Based Study 原发性高血压患者血压变异性的决定因素:一项基于调查的研究
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.125026
A. Kamal
Background: Blood pressure variability (BPV) in hypertensive patients is implicated as a remarkable feature leading to additional cardiovascular complications. The aim of the study was to identify the determinants influencing BPV among patients with essential hypertension seen at the Cardiology department of the faculty of medicine, University of Alexandria, Egypt. Methods: This was a descriptive cross-sectional hospital-based study conducted from August 2019 to November 2019. All the eligible patients were made to fill out a standard questionnaire to obtain family and personal clinical history and undergo routine physical examination, laboratory tests and 24-hour ambulatory blood pressure monitoring. BPV was summarized as the standard deviation (SD) of all-day systolic and diastolic BP in both normal patients (with SD < 11) and abnormal patients (with SD ≥ 11). Results: Out of a total of 114 patients, 18 (15.8%) non-hypertensive patients were included in the control group and the remaining 96 (84.3%) were classified based on the degree of hypertension. BPV in all these patients was found to be significantly related to the male gender, a mild or moderate degree of hypertension, high prevalence of non-dipping, diabetes, use of beta-blockers as antihypertensive medication, heart rate variability, BMI, and increased day-time variability. Conclusion: Variability in blood pressure influenced by different intrinsic and extrinsic factors plays an important role in the management of hypertension. In order to reduce the burden of disease and for a better quality of life for hypertensive patients, it is important that physicians start considering lowering BPV in addition to reducing physiological BP levels.
背景:高血压患者的血压变异性(BPV)被认为是导致额外心血管并发症的一个显著特征。该研究的目的是确定影响埃及亚历山大大学医学院心脏病学系原发性高血压患者BPV的决定因素。方法:这是一项描述性横断面医院研究,于2019年8月至2019年11月进行。所有符合条件的患者填写标准问卷,了解家庭和个人病史,并进行常规体检、实验室检查和24小时动态血压监测。BPV总结为正常患者(SD < 11)和异常患者(SD≥11)全天收缩压和舒张压的标准差(SD)。结果:114例患者中,非高血压患者18例(15.8%)为对照组,其余96例(84.3%)按高血压程度分类。所有这些患者的BPV均与男性、轻度或中度高血压、非高血压高发、糖尿病、β受体阻滞剂作为降压药物的使用、心率变异性、BMI和增加的日间变异性显著相关。结论:受不同内外部因素影响的血压变异性在高血压的治疗中起着重要作用。为了减轻疾病负担和提高高血压患者的生活质量,医生在降低生理血压水平的同时考虑降低BPV是很重要的。
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引用次数: 0
Cardiac Amyloidosis: A Case Report of Seven Patients 心脏淀粉样变性7例报告
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.123017
N. Djita, I. Sylla, Aissatou Barry, Murielle Ahodakin, D. Sylla, E. Y. Baldé, M. B. Bah, Houzeiph Abdou Lassissi, A. Koné, Sana Soumra, M. Balde, M. Béavogui, M. Baldé, Noura Feniche
Introduction: Cardiac amyloidosis is a rare and under-diagnosed disease. The objective of this study was to collect cases of cardiac amyloidosis in patients hospitalized in the cardiology department of the Centre Hospitalier Intercommunal Alençon-Mamers (CHICAM). Patients and Methods: This was a retrospective descriptive study of the records of patients diagnosed with cardiac amyloidosis. The study took place in the cardiology department of the CHICAM over 12 months (from January 1, 2020 to December 31, 2020). We included the files of patients in whom the diagnosis of cardiac amyloidosis was confirmed on the basis of clinical, echocardiographic, biological, scintigraphic and cardiac MRI evidence. Results: Seven patients were included. The mean age was 86.71 years. Six men for one woman. Most of the patients were in heart failure. There was one case of periorbital ecchymosis. Troponinemia was increased in three patients, NTproBNP was always high with a mean of 1000 ng/L. Cardiac echography showed a hyperbright septum in four cases, concentric hypertrophy of the left ventricle with a mean interventricular septum in diastole of 13.85 mm. Six cases were senile transthyretin amyloidosis (TTR), one case was mutated transthyretin amyloidosis (TTRm). Two cases of death were noted. Conclusion: Cardiac amyloidosis has a poor prognosis due to delayed diagnosis.
简介:心脏淀粉样变性是一种罕见且诊断不足的疾病。本研究的目的是收集在社区间alen- mamers医院中心(CHICAM)心内科住院的患者的心脏淀粉样变性病例。患者和方法:这是一项回顾性描述性研究,记录了被诊断为心脏淀粉样变的患者。该研究在CHICAM心内科进行了12个月(从2020年1月1日到2020年12月31日)。我们纳入了在临床、超声心动图、生物学、科学成像和心脏MRI证据的基础上确诊为心脏淀粉样变的患者档案。结果:纳入7例患者。平均年龄86.71岁。六男配一女。大多数病人都有心力衰竭。眼眶周围淤斑1例。3例患者肌钙蛋白血症升高,NTproBNP一直偏高,平均为1000 ng/L。心脏超声显示4例左心室室间隔过亮,左心室同心圆肥大,舒张期平均室间隔13.85 mm。老年性甲状腺转蛋白淀粉样变性(TTR) 6例,突变型甲状腺转蛋白淀粉样变性(TTRm) 1例。注意到两起死亡案件。结论:心脏淀粉样变因诊断迟缓,预后较差。
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引用次数: 0
Transcatheter Aortic Valve Replacement in High-Risk Surgical Patient with Severe Aortic Insufficiency 经导管主动脉瓣置换术治疗严重主动脉不全高危手术患者
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.127038
F. Khan, Danielle Cannon, Alon Yarkoni
Background: Transcatheter aortic valve replacement (TAVR) is approved by the FDA for severe aortic stenosis (AS) in patients of all surgical risk categories but has yet to be studied for its utility in aortic insufficiency (AI), despite the need for a safe alternative to surgery for prohibitive surgical risk patients. Case Report: We describe a case of a female patient who presented with acute decompensated congestive heart failure (CHF) with New York Heart Association (NYHA) Class IV symptoms. She was found to have severe AI leading to acute decompensation. Two years prior to this, she had aortic valve endocarditis that had potentially resulted in severe AI. Considering her underling comorbidities including diabetes mellitus, hypertension, morbid obesity and multiple myeloma on active chemotherapy at the time of evaluation, the patient was a high-risk surgical candidate for surgical aortic valve repair (SAVR) in view of elevated risk of mortality, infection, and poor wound healing. After critical and comprehensive assessment, transcatheter aortic valve intervention was considered to be an appropriate choice of treatment. TAVR was successfully performed that resulted in immediate improvement of aortic valve func-tion. On subsequent follow-ups, she demonstrated markedly improved symptoms and reduced status to NYHA Class II HF symptoms. Conclusion: TAVR is a potential treatment modality for patients with severe AI who are poor surgical candidates for SAVR. We hope our case contributes to the growing pool of studies investigating the utility of TAVR procedure in patients with severe AI.
背景:经导管主动脉瓣置换术(TAVR)已被FDA批准用于所有手术风险类别的严重主动脉瓣狭窄(AS)患者,但尚未研究其在主动脉功能不全(AI)中的应用,尽管需要一种安全的手术替代方案。病例报告:我们描述了一例女性患者谁提出了急性失代偿性充血性心力衰竭(CHF)与纽约心脏协会(NYHA)四级症状。她被发现患有严重的人工智能,导致急性代偿丧失。在此之前两年,她患有主动脉瓣心内膜炎,可能导致严重的AI。考虑到患者的潜在合并症包括糖尿病、高血压、病态肥胖和多发性骨髓瘤,在评估时正在积极化疗,鉴于患者死亡率、感染风险升高和伤口愈合不良,该患者是手术主动脉瓣修复(SAVR)的高危手术候选者。经过严格和全面的评估,经导管主动脉瓣介入治疗被认为是一种合适的治疗选择。TAVR手术成功,主动脉瓣功能立即得到改善。在随后的随访中,患者表现出明显的症状改善,并降低到NYHA II类HF症状。结论:对于手术条件差的严重AI患者,TAVR是一种潜在的治疗方式。我们希望我们的病例有助于研究TAVR手术在严重AI患者中的应用。
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引用次数: 0
Autonomic Function in Individuals with Slow Heart Rate Response following an Exercise Stress Test 运动应激试验后慢心率反应个体的自主神经功能
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.126028
I. Goldfarb, Kobi Serr, S. Segev, J. Shemesh, I. Goldenberg, M. Scheinowitz
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引用次数: 0
Impact of Acute Ischemia-Reperfusion Injury on Left Ventricular Pressure-Volume Relations in Dogs 急性缺血再灌注损伤对犬左心室压力-容积关系的影响
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.124024
J. Kingma, Denys Simard, J. Rouleau
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引用次数: 0
Papillary Muscle Relocation in Secondary Mitral Regurgitation: Midterm Outcomes 继发性二尖瓣返流的乳头肌移位:中期结果
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.124022
Pramote Porapakkham, P. Porapakkham
Background: Mitral valve repair in secondary mitral regurgitation is still uncertain as the chance of recurrence is approximately 30 percent after solely undersized annuloplasty. Some procedures adding to the subvalvular level are proposed to alleviate the recurrent rate. This study was to evaluate the clinical and echocardiographic outcomes of papillary muscle relocation plus undersized ring in secondary mitral regurgitation (2 nd MR). Methods: Medical records of moderate to severe 2 nd MR with tethering depth of more than 1 cm patients who underwent papillary muscle relocation plus undersized ring from 2014 to 2020 were reviewed. Clinical and echocardiographic parameters before and after operation were analyzed. Results: Thirty-two patients were included during the 6-year period. There was no perioperative mortality. Two patients died at one year from ischemic stroke and car accidents with overall 5-year survival of 93.7%. All patients were in NYHA class I and II with MR grading as trivial or mild at a median follow-up of 33 months. Postoperative mean tenting depth, area and posterior leaflet angle decreased remarkably from 1.18 cm, 2.61 cm 2 and 46.5 degree to 0.65 cm, 1.22 cm 2 and 28.6 degree, respectively (p < 0.001, 0.02, and 0.01). Moreover, left ventricular function and remodeling were also notably improved (EF; 38.2% vs 49.1%: p = 0.018, LVEDD; 62.8 vs 54.6 mm: p = 0.005, LVESD; 50.2 vs 42.4 mm: p = 0.01). Conclusions: Papillary muscle relocation combined with undersized annuloplasty improved mid-term clinical outcomes. Apart from reduction of recurrent MR rate, restoration of mitral configuration and reverse LV remodeling could be the effect of adding subvalvular correction in this pathology.
背景:二尖瓣修复在继发性二尖瓣返流中仍然不确定,因为仅在小尺寸环成形术后复发率约为30%。提出了一些增加瓣下水平的手术来减轻复发率。本研究旨在评价继发性二尖瓣反流(二次MR)中乳头状肌移位加小环的临床和超声心动图结果。方法:回顾2014 ~ 2020年中重度2次MR系扎深度大于1cm患者行乳头肌移位加过小环手术的病历。分析手术前后临床及超声心动图参数。结果:6年内纳入32例患者。无围手术期死亡。2例患者一年内死于缺血性脑卒中和车祸,5年总生存率为93.7%。所有患者均为NYHA I级和II级,MR分级为轻微或轻度,中位随访时间为33个月。术后平均帐篷深度、面积和后小叶角分别从1.18 cm、2.61 cm 2和46.5度显著降低至0.65 cm、1.22 cm 2和28.6度(p < 0.001、0.02和0.01)。此外,左心室功能和重构也明显改善(EF;38.2% vs 49.1%: p = 0.018, LVEDD;62.8 vs 54.6 mm: p = 0.005, LVESD;50.2 vs 42.4 mm: p = 0.01)。结论:乳头肌移位联合小尺寸环成形术改善了中期临床结果。除了降低复发率外,二尖瓣形态的恢复和左室的逆转重构可能是在这种病理中增加瓣下矫正的效果。
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引用次数: 0
Cardiovascular and Cerebrovascular Prognosis at 5 Years of Patients Who Presented with an Ischemic Stroke at Principal Hospital of Dakar 达喀尔主要医院缺血性脑卒中患者5年的心脑血管预后
Pub Date : 2022-01-01 DOI: 10.4236/wjcd.2022.121008
W. N. Mboup, M. Ka, S. C. Ndao, D. Balde, D. Ba, K. Dia, Pape Diadji Fall, M. C. Mboup
Aims: To determine the cardiovascular and cerebrovascular prognosis at 5 years of patients who underwent an ischemic stroke in Senegal. Methods: We performed a descriptive, retrospective and exhaustive study conducted at Principal Hospital of Dakar. We included all patients hospitalized at Principal Hospital of Dakar from 2013 to 2019 for an ischemic stroke confirmed by a cerebral CT-Scanner or by magnetic resonance imaging, and who survived the acute phase. Results: Overall, one hundred and seventy-one (171) patients were gathered. Ninety-six (96) male patients account for 56.14% and seventy-five (75) female patients account for 43.86%, with a sex ratio of 1.28. Patients’ mean age was 66.33 ± 13.99 years. Twenty-one (21) young patients (12.35%), aged less than 50 years, presented with an ischemic stroke. Myocardial infarction was found in a female patient (0.6%) 3 months after she experienced an ischemic stroke, nine (9) patients (5.29%) underwent a recurrence of the ischemic stroke with a mean recurrence period of 8 months and extremes ranging from sion: Long-term prognosis of ischemic stroke remains unclear in Senegal. Therefore, a strategy for primary prevention is highly crucial and it requires the control of risk factors in general and that of high blood pressure in par-ticular.
目的:确定塞内加尔5年缺血性脑卒中患者的心脑血管预后。方法:我们在达喀尔主要医院进行了一项描述性、回顾性和详尽的研究。我们纳入了2013年至2019年在达喀尔主要医院住院的所有经脑ct扫描仪或磁共振成像证实的缺血性中风患者,这些患者在急性期存活下来。结果:共收集了171例患者。男性96例占56.14%,女性75例占43.86%,性别比为1.28。患者平均年龄66.33±13.99岁。年龄小于50岁的21(21)例年轻患者(12.35%)表现为缺血性脑卒中。1例女性患者(0.6%)在经历缺血性卒中3个月后发现心肌梗死,9例(5.29%)患者出现缺血性卒中复发,平均复发时间为8个月,极端情况如下:塞内加尔缺血性卒中的长期预后尚不清楚。因此,一级预防战略是非常重要的,它需要控制一般的风险因素,特别是高血压的风险因素。
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心血管病(英文)
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