Pub Date : 2022-04-01DOI: 10.1364/OTS.2022.OTu2D.3
Zijian Deng, Xiangkun Xu, Iulian Iordachita, Hamid Dehghani, Bin Zhang, John W Wong, Ken Kang-Hsin Wang
We constructed a bioluminescence tomography(BLT) to localize soft tissue targets for preclinical radiotherapy study. With the threshold and margin designed for target volume, BLT can provide opportunity to perform conformal irradiation to malignancy.
{"title":"Bioluminescence tomography system for in vivo irradiation guidance.","authors":"Zijian Deng, Xiangkun Xu, Iulian Iordachita, Hamid Dehghani, Bin Zhang, John W Wong, Ken Kang-Hsin Wang","doi":"10.1364/OTS.2022.OTu2D.3","DOIUrl":"https://doi.org/10.1364/OTS.2022.OTu2D.3","url":null,"abstract":"<p><p>We constructed a bioluminescence tomography(BLT) to localize soft tissue targets for preclinical radiotherapy study. With the threshold and margin designed for target volume, BLT can provide opportunity to perform conformal irradiation to malignancy.</p>","PeriodicalId":72390,"journal":{"name":"Biomedical optics (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10047798/pdf/nihms-1884426.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9224158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-01DOI: 10.1364/translational.2022.jtu3a.45
Zhishen Tong, Zijian Deng, Ken Kang-Hsin Wang
We presented a single-pixel bioluminescence tomography (SPBLT) to monitor single or few cells in live animal. Simulations are proposed to validate the capability of SPBLT in detecting weak bioluminescence signal emitted from cells in vivo.
{"title":"Ultra-sensitive single pixel bioluminescence tomography for <i>in vivo</i> cell tracking.","authors":"Zhishen Tong, Zijian Deng, Ken Kang-Hsin Wang","doi":"10.1364/translational.2022.jtu3a.45","DOIUrl":"https://doi.org/10.1364/translational.2022.jtu3a.45","url":null,"abstract":"<p><p>We presented a single-pixel bioluminescence tomography (SPBLT) to monitor single or few cells in live animal. Simulations are proposed to validate the capability of SPBLT in detecting weak bioluminescence signal emitted from cells <i>in vivo</i>.</p>","PeriodicalId":72390,"journal":{"name":"Biomedical optics (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10044448/pdf/nihms-1884425.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9224154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luke Hardy, Daniel Sforza, Iulian Iordachita, Xiangkun Xu, John W Wong, Ken Kang-Hsin Wang
We proposed to build a mobile fluorescence tomography (mFT) system as an image-guided platform for pre-clinical radiotherapy research. The mFT system is expected to localize functional target/tumor, guide irradiation, and provide longitudinal treatment assessment.
{"title":"Development of a Mobile Fluorescence Tomography-guided System for Pre-clinical Radiotherapy Research.","authors":"Luke Hardy, Daniel Sforza, Iulian Iordachita, Xiangkun Xu, John W Wong, Ken Kang-Hsin Wang","doi":"10.1364/ots.2020.sw1d.6","DOIUrl":"https://doi.org/10.1364/ots.2020.sw1d.6","url":null,"abstract":"<p><p>We proposed to build a mobile fluorescence tomography (mFT) system as an image-guided platform for pre-clinical radiotherapy research. The mFT system is expected to localize functional target/tumor, guide irradiation, and provide longitudinal treatment assessment.</p>","PeriodicalId":72390,"journal":{"name":"Biomedical optics (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457533/pdf/nihms-1644934.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39443733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}