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Chinese physics B = Zhongguo wu li B最新文献

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Electron beam irradiation on novel coronavirus (COVID-19): A Monte-Carlo simulation. 电子束辐照新型冠状病毒(新冠肺炎):蒙特-卡洛模拟。
Pub Date : 2020-04-01 DOI: 10.1088/1674-1056/ab7dac
Guobao Feng, Lu Liu, Wanzhao Cui, Fang Wang

The novel coronavirus pneumonia triggered by COVID-19 is now raging the whole world. As a rapid and reliable killing COVID-19 method in industry, electron beam irradiation can interact with virus molecules and destroy their activity. With the unexpected appearance and quickly spreading of the virus, it is urgently necessary to figure out the mechanism of electron beam irradiation on COVID-19. In this study, we establish a virus structure and molecule model based on the detected gene sequence of Wuhan patient, and calculate irradiated electron interaction with virus atoms via a Monte Carlo simulation that track each elastic and inelastic collision of all electrons. The characteristics of irradiation damage on COVID-19, atoms' ionizations and electron energy losses are calculated and analyzed with regions. We simulate the different situations of incident electron energy for evaluating the influence of incident energy on virus damage. It is found that under the major protecting of an envelope protein layer, the inner RNA suffers the minimal damage. The damage for a ∼100-nm-diameter virus molecule is not always enhanced by irradiation energy monotonicity, for COVID-19, the irradiation electron energy of the strongest energy loss damage is 2 keV.

新冠肺炎引发的新型冠状病毒肺炎正在全球肆虐。电子束辐照作为工业上快速可靠的杀死新冠肺炎的方法,可以与病毒分子相互作用并破坏其活性。随着病毒的突然出现和迅速传播,研究电子束辐照对新冠肺炎的作用机制迫在眉睫。在本研究中,我们基于武汉患者检测到的基因序列建立了一个病毒结构和分子模型,并通过蒙特卡罗模拟计算了辐照电子与病毒原子的相互作用,该模拟跟踪了所有电子的每次弹性和非弹性碰撞。计算并分析了新冠肺炎辐照损伤、原子电离和电子能量损失的区域特征。我们模拟了入射电子能量的不同情况,以评估入射能量对病毒损伤的影响。研究发现,在包膜蛋白层的主要保护下,内部RNA受到的损伤最小。对直径约为100-nm的病毒分子的损伤并不总是因辐射能量单调性而增强,对于新冠肺炎,最强能量损失损伤的辐射电子能量为2keV。
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引用次数: 0
Analytically determining frequency and amplitude of spontaneous alpha oscillation in Jansen's neural mass model using the describing function method. 用描述函数法解析确定Jansen神经质量模型中自发α振荡的频率和振幅。
Pub Date : 2018-04-01 DOI: 10.1088/1674-1056/27/4/048701
Yao Xu, Chun-Hui Zhang, Ernst Niebur, Jun-Song Wang

Spontaneous alpha oscillations are a ubiquitous phenomenon in the brain and play a key role in neural information processing and various cognitive functions. Jansen's neural mass model (NMM) was initially proposed to study the origin of alpha oscillations. Most of previous studies of the spontaneous alpha oscillations in the NMM were conducted using numerical methods. In this study, we aim to propose an analytical approach using the describing function method to elucidate the spontaneous alpha oscillation mechanism in the NMM. First, the sigmoid nonlinear function in the NMM is approximated by its describing function, allowing us to reformulate the NMM and derive its standard form composed of one nonlinear part and one linear part. Second, by conducting a theoretical analysis, we can assess whether or not the spontaneous alpha oscillation would occur in the NMM and, furthermore, accurately determine its amplitude and frequency. The results reveal analytically that the interaction between linearity and nonlinearity of the NMM plays a key role in generating the spontaneous alpha oscillations. Furthermore, strong nonlinearity and large linear strength are required to generate the spontaneous alpha oscillations.

自发的阿尔法振荡是大脑中普遍存在的现象,在神经信息处理和各种认知功能中发挥着关键作用。詹森的神经质量模型(NMM)最初是为了研究阿尔法振荡的起源而提出的。以前对NMM中自发α振荡的大多数研究都是使用数值方法进行的。在这项研究中,我们旨在提出一种使用描述函数方法来阐明NMM中自发α振荡机制的分析方法。首先,通过描述函数来近似NMM中的S形非线性函数,使我们能够重新表述NMM,并导出其由一个非线性部分和一个线性部分组成的标准形式。其次,通过进行理论分析,我们可以评估NMM中是否会发生自发的α振荡,此外,还可以准确地确定其振幅和频率。分析结果表明,NMM的线性和非线性之间的相互作用在自发α振荡的产生中起着关键作用。此外,产生自发的α振荡需要强的非线性和大的线性强度。
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引用次数: 3
Nanoscaled ZnO films used as enhanced substrates for fluorescence detection of dyes. 纳米氧化锌薄膜用作染料荧光检测的增强底物。
Pub Date : 2012-03-01 DOI: 10.1088/1674-1056/21/3/037803
Liu Yan-Song, Yi Fu, Ramachandram Badugu, Joseph R Lakowicz, Xu Xiao-Liang

The ability of nanoscaled ZnO films to enhance fluorescence was studied. We found that the fluorescence intensities of Cy5, rhodamine 6G, and fluorescein can be enhanced about 10-fold on nanoscaled ZnO films as compared to that on glass substrates. The lifetimes of all samples were measured, and no obvious change in lifetime was observed for dyes on different substrates. The mechanism for the nanoscaled ZnO film enhanced fluorescence appears to be different from that for the metal-fluorophore systems.

研究了纳米氧化锌薄膜增强荧光的能力。我们发现Cy5、罗丹明6G和荧光素在纳米ZnO薄膜上的荧光强度比在玻璃衬底上的荧光强度提高了约10倍。测量了所有样品的寿命,不同底物上的染料寿命没有明显变化。纳米ZnO薄膜增强荧光的机理与金属-荧光团体系不同。
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引用次数: 0
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Chinese physics B = Zhongguo wu li B
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