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International journal of functional informatics and personalised medicine最新文献

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LOINC® - A Universal Catalog of Individual Clinical Observations and Uniform Representation of Enumerated Collections. LOINC® - 单个临床观察指标的通用目录和枚举集合的统一表述。
Pub Date : 2010-01-01 Epub Date: 2011-05-23 DOI: 10.1504/IJFIPM.2010.040211
Daniel J Vreeman, Clement J McDonald, Stanley M Huff

In many areas of practice and research, clinical observations are recorded on data collection forms by asking and answering questions, yet without being represented in accepted terminology standards these results cannot be easily shared among clinical care and research systems. LOINC contains a well-developed model for representing variables, answer lists, and the collections that contain them. We have successfully added many assessments and other collections of variables to LOINC in this model. By creating a uniform representation and distributing it worldwide at no cost, LOINC aims to lower the barriers to interoperability among systems and make this valuable data available across settings when and where it is needed.

在许多实践和研究领域,临床观察结果都是通过提问和回答问题的方式记录在数据采集表上的,但如果没有公认的术语标准来表示,这些结果就无法在临床护理和研究系统之间轻松共享。LOINC 包含一个完善的模型,用于表示变量、答案列表以及包含这些变量的集合。我们已经成功地将许多评估和其他变量集合添加到了 LOINC 这一模型中。通过创建统一的表示方法并在全球范围内免费分发,LOINC 旨在降低系统间互操作性的障碍,并使这些宝贵的数据能够在需要的时间和地点跨环境使用。
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引用次数: 0
Imaging informatics for personalised medicine: applications and challenges. 个性化医疗成像信息学:应用和挑战。
Pub Date : 2009-01-01 DOI: 10.1504/IJFIPM.2009.027587
Tianming Liu, Hanchuan Peng, Xiaobo Zhou

Imaging informatics has emerged as a major research theme in biomedicine in the last few decades. Currently, personalised, predictive and preventive patient care is believed to be one of the top priorities in biomedical research and practice. Imaging informatics plays a major role in biomedicine studies. This paper reviews main applications and challenges of imaging informatics in biomedicine.

近几十年来,影像信息学已成为生物医学领域的一个重要研究课题。目前,个性化、预测性和预防性的病人护理被认为是生物医学研究和实践的重中之重。影像信息学在生物医学研究中起着重要的作用。本文综述了影像信息学在生物医学中的主要应用及面临的挑战。
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引用次数: 5
Impulse response and Modulation Transfer Function analysis for Shift-And-Add and Back Projection image reconstruction algorithms in Digital Breast Tomosynthesis (DBT). 数字乳腺断层合成(DBT)中移位加和反向投影图像重建算法的脉冲响应和调制传递函数分析。
Pub Date : 2008-01-01 DOI: 10.1504/IJFIPM.2008.020187
Ying Chen, Joseph Y Lo, James T Dobbins

Breast cancer is second only to lung cancer as the leading cause of non-preventable cancer death in women. Digital Breast Tomosynthesis (DBT) is a promising technique to improve early breast cancer detection. In this paper, we present the impulse response and Modulation Transfer Function (MTF) analysis to quantitatively compare Shift-And-Add (SAA) and point-by-point Back Projection (BP) three-dimensional image reconstruction algorithms in DBT. A Filtered Back Projection (FBP) deblurring algorithm based on point-by-point BP was used to demonstrate deblurred tomosynthesis images.

乳腺癌是仅次于肺癌的第二大女性不可预防的癌症死亡原因。数字乳腺断层合成(DBT)是一种很有前途的技术,可以提高乳腺癌的早期检测。在本文中,我们提出了脉冲响应和调制传递函数(MTF)分析,以定量地比较位移和添加(SAA)和逐点反向投影(BP)三维图像重建算法在DBT。采用基于逐点BP的滤波反投影(FBP)去模糊算法对去模糊的断层合成图像进行了演示。
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引用次数: 4
New statistical learning theory paradigms adapted to breast cancer diagnosis/classification using image and non-image clinical data. 新的统计学习理论范式适用于使用图像和非图像临床数据的乳腺癌诊断/分类。
Pub Date : 2008-01-01 DOI: 10.1504/ijfipm.2008.020183
Walker H Land, John J Heine, Tom Raway, Alda Mizaku, Nataliya Kovalchuk, Jack Y Yang, Mary Qu Yang

The automated decision paradigms presented in this work address the false positive (FP) biopsy occurrence in diagnostic mammography. An EP/ES stochastic hybrid and two kernelized Partial Least Squares (K-PLS) paradigms were investigated with following studies: methodology performance comparisonsautomated diagnostic accuracy assessments with two data sets. The findings showed: the new hybrid produced comparable results more rapidlythe new K-PLS paradigms train and operate Essentially in real time for the data sets studied. Both advancements are essential components for eventually achieving the FP reduction goal, while maintaining acceptable diagnostic sensitivities.

在这项工作中提出的自动决策范式解决假阳性(FP)活检发生在诊断乳房x光检查。研究了EP/ES随机混合模型和两个核化偏最小二乘(K-PLS)模型,并进行了以下研究:方法性能比较和两组数据集的自动诊断准确性评估。研究结果表明:新的混合产生可比的结果更快,新的K-PLS范式训练和运行基本上是实时的数据集研究。这两项进展都是最终实现减少FP目标的重要组成部分,同时保持可接受的诊断灵敏度。
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引用次数: 1
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International journal of functional informatics and personalised medicine
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