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Research priorities in geriatric oncology for 2013 and beyond. 2013年及以后老年肿瘤学的研究重点。

Cancer forum

Pub Date : 2013-11-01

Supriya Mohile, William Dale, Allison Magnuson, Nayana Kamath, Arti Hurria

The incidence of cancer increases with advanced age. Unfortunately, there is a significant lack of evidence regarding the safety and efficacy of treatments. The oncology community also lacks information regarding which older patients are most likely to benefit from treatment without undue toxicities. Interventions to lower symptoms and reduce long-term complications from cancer and cancer treatment in older patients are urgently needed. Establishing research priorities in geriatric oncology could help guide researchers and focus efforts on interventions that have the highest likelihood of improving outcomes. The Cancer and Aging Research Group, in partnership with the National Institute on Aging and National Cancer Institute, held linked conferences as part of a U13 grant in September of 2010 and November of 2012, summarising the gaps in knowledge in geriatric oncology and recommending ways to close these gaps. The overall purpose of this review is to highlight the important research priorities in geriatric oncology from the literature and from the previous U13 meetings. More evidence regarding the treatment of older cancer patients is urgently needed given the rapid aging of the population.

癌症的发病率随着年龄的增长而增加。不幸的是，关于治疗的安全性和有效性的证据严重缺乏。肿瘤学界也缺乏关于哪些老年患者最有可能从治疗中获益而没有过度毒性的信息。迫切需要采取干预措施，以减轻老年患者癌症和癌症治疗的症状和减少长期并发症。确定老年肿瘤学的研究重点可以帮助指导研究人员，并将精力集中在最有可能改善结果的干预措施上。癌症和衰老研究小组与国家老龄研究所和国家癌症研究所合作，在2010年9月和2012年11月举行了相关会议，作为U13资助的一部分，总结了老年肿瘤学知识的差距，并建议了缩小这些差距的方法。本综述的总体目的是从文献和以前的U13会议中强调老年肿瘤学的重要研究重点。鉴于人口的快速老龄化，迫切需要更多关于老年癌症患者治疗的证据。

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