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SAS® Macros for Computing Causal Mediated Effects in Two- and Three-Wave Longitudinal Models. SAS®宏,用于计算两波和三波纵向模型中的因果中介效应。
Pub Date : 2018-01-01
Matthew J Valente, David P MacKinnon

Mediation analysis is a statistical technique for investigating the extent to which a mediating variable transmits the effect of an independent variable to a dependent variable. Because it is used in many fields, there have been rapid developments in statistical mediation. The most cutting-edge statistical mediation analysis focuses on the causal interpretation of mediated effects. Causal inference is particularly challenging in mediation analysis because of the difficulty of randomizing subjects to levels of the mediator. The focus of this paper is on updating three existing SAS® macros (%TWOWAVEMED, %TWOWAVEMONTECARLO, and %TWOWAVEPOSTPOWER, presented at SAS® Global Forum 2017) in two important ways. First, the macros are updated to incorporate new cutting-edge methods for estimating longitudinal mediated effects from the Potential Outcomes Framework for causal inference. The two new methods are inverse-propensity weighting, an application of propensity scores, and sequential G-estimation. The causal inference methods are revolutionary because they frame the estimation of mediated effects in terms of differences in potential outcomes, which align more naturally with how researchers think about causal inference. Second, the macros are updated to estimate mediated effects across three waves of data. The combination of these new causal inference methods and three waves of data enable researchers to test how causal mediated effects develop and maintain over time.

中介分析是一种统计技术,用于研究中介变量将自变量的影响传递给因变量的程度。由于它在许多领域都有应用,统计中介也得到了快速发展。最前沿的统计中介分析侧重于对中介效应的因果解释。因果推理在中介分析中尤其具有挑战性,因为很难将受试者随机划分为中介水平。本文的重点是以两种重要的方式更新三个现有的SAS®宏(在2017年SAS®全球论坛上发表的%TWOWEEMED、%TWOWVEMONTECARLO和%TWOWEVEPOSTPOWER)。首先,对宏进行了更新,以纳入新的尖端方法,从因果推断的潜在结果框架中估计纵向中介效应。这两种新方法是反向倾向加权、倾向得分的应用和顺序G估计。因果推断方法是革命性的,因为它们根据潜在结果的差异来确定中介效应的估计,这与研究人员对因果推断的看法更加自然。其次,更新宏以估计三波数据中的中介效应。这些新的因果推断方法和三波数据的结合使研究人员能够测试因果中介效应是如何随着时间的推移而发展和维持的。
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引用次数: 0
SAS® Macros for Computing the Mediated Effect in the Pretest-Posttest Control Group Design. SAS®宏用于计算前测后测对照组设计中的中介效应。
Pub Date : 2017-01-01
Matthew J Valente, David P MacKinnon

Mediation analysis is a statistical technique for investigating the extent to which a mediating variable transmits the relation of an independent variable to a dependent variable. Because it is useful in many fields, there have been rapid developments in statistical mediation methods. The most cutting-edge statistical mediation analysis focuses on the causal interpretation of mediated effect estimates. Cause-and-effect inferences are particularly challenging in mediation analysis because of the difficulty of randomizing subjects to levels of the mediator (MacKinnon, 2008). The focus of this paper is how incorporating longitudinal measures of the mediating and outcome variables aides in the causal interpretation of mediated effects. This paper provides useful SAS® tools for designing adequately powered studies to detect the mediated effect. Three SAS macros were developed using the powerful but easy-to-use REG, CALIS, and SURVEYSELECT procedures to do the following: (1) implement popular statistical models for estimating the mediated effect in the pretest-posttest control group design; (2) conduct a prospective power analysis for determining the required sample size for detecting the mediated effect; and (3) conduct a retrospective power analysis for studies that have already been conducted and a required sample to detect an observed effect is desired. We demonstrate the use of these three macros with an example.

中介分析是一种统计技术,用于调查中介变量将自变量与因变量的关系传递到何种程度。由于它在许多领域都很有用,因此统计中介方法得到了迅速的发展。最尖端的统计中介分析侧重于中介效应估计的因果解释。因果推理在中介分析中尤其具有挑战性,因为很难将受试者随机分配到中介水平(MacKinnon, 2008)。本文的重点是如何结合纵向测量的中介和结果变量辅助中介效应的因果解释。本文提供了有用的SAS®工具,用于设计足够有力的研究来检测介导效应。使用功能强大且易于使用的REG、CALIS和SURVEYSELECT程序开发了三个SAS宏,以完成以下工作:(1)在前测后测对照组设计中实施流行的统计模型来估计中介效应;(2)进行前瞻性功效分析,确定检测中介效应所需的样本量;(3)对已经进行的研究进行回顾性功效分析,并且需要足够的样本来检测观察到的效果。我们通过一个示例来演示这三个宏的使用。
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引用次数: 0
DATA CLEANING: LONGITUDINAL STUDY CROSS-VISIT CHECKS. 数据清理:纵向研究交叉访问检查。
Pub Date : 2014-03-01
Lauren Parlett

Cross-visit checks are a vital part of data cleaning for longitudinal studies. The nature of longitudinal studies encourages repeatedly collecting the same information. Sometimes, these variables are expected to remain static, go away, increase, or decrease over time. This presentation reviews the naïve and the better approaches at handling one-variable and two-variable consistency checks. For a single-variable check, the better approach features the new ALLCOMB function, introduced in SAS® 9.2. For a two-variable check, the better approach uses a BY PROCESSING variable to flag inconsistencies. This paper will provide you the tools to enhance your longitudinal data cleaning process.

交叉访问检查是纵向研究数据清理的重要组成部分。纵向研究的本质鼓励重复收集相同的信息。有时,这些变量会随着时间的推移保持静态、消失、增加或减少。本演讲回顾了naïve以及处理单变量和双变量一致性检查的更好方法。对于单变量检查,更好的方法是SAS®9.2中引入的新的ALLCOMB功能。对于双变量检查,更好的方法是使用BY PROCESSING变量标记不一致性。本文将为您提供增强纵向数据清理过程的工具。
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引用次数: 0
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