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Research Trends in the Application of Yoga to Human Health: A Data Science Approach. 瑜伽对人体健康应用的研究趋势:数据科学方法。
Chaitra Gururaja, D Rangaprakash, Gopikrishna Deshpande

Yoga is an integrative mind-body system of wellbeing developed in India since at least three millennia. Yoga has gained considerable attention in recent decades, partly driven by recent research and evidence about its effectiveness. In this work, we extracted research trends on the effects of Yoga on human health from the US National Library of Medicine's PubMed database (peer-reviewed journal papers). We found that Yoga research spans all organ systems and system-wide issues such as pain and cancer. Research on the nervous system far outpaces other systems, which is expected because of the effects of breathing and exercise on stress reduction, which has been a major application of Yoga. The next cluster of impact concerns the musculoskeletal system and pain (both related to the exercise [asana] aspects of Yoga), as well as cardiovascular/endocrine (also related to stress) and cancer. Stress and mental health, pain, diabetes, and cancer are health issues for which a permanent cure is not available in a majority of cases in modern medicine, although alleviating treatments are available. This has probably fueled interest in complementary approaches such as Yoga for these health issues. Research timeline shows that Yoga-related research largely expanded only after the 2000s. There was a specific uptick after 2004. Similar trends are seen if we look at just clinical trials or randomized control trials (RCTs) or systematic reviews. The percentage of trials (Clinical and RCT) among published literature is around 10-15 % This is comparable to other fields that gained traction around 2000s (e.g. non-invasive brain stimulation). Geographical distribution shows that 37% of all Yoga related research output originates in the USA, 19% from India, 13% from Europe and 31% from the rest of the world. Therefore, the interest is widespread and global. At least the uptick in Yoga-related research in the US post-2000s can be attributed to a substantial jump in funding between 1998 and 2005 from US National Institutes of Health's National Center for Complementary and Integrative Health (NCCIH). We can only surmise that research in this field reached a critical mass in late-1990s, which infused more money into this field, generating more research and creating a positive feedback loop that has sustained the growth so far. We propose that in order to sustain or even accelerate future research in the area, rigor and reproducibility must be enhanced in addition to performing more RCT and clinical trials (increasing % of trials to 20-25% from 10-15%). The fruits of research in the field has to reach the common man in terms of evidence-based solutions to health issues. Without this, accelerated funding in democracies such as India and the USA will not be realizable.

瑜伽是一种身心一体的健康系统,在印度发展了至少三千年。近几十年来,瑜伽获得了相当多的关注,部分原因是最近有关其有效性的研究和证据。在这项工作中,我们从美国国家医学图书馆的PubMed数据库(同行评议的期刊论文)中提取了瑜伽对人体健康影响的研究趋势。我们发现瑜伽的研究涵盖了所有的器官系统和系统范围的问题,比如疼痛和癌症。对神经系统的研究远远超过其他系统,这是预期的,因为呼吸和运动对减轻压力的影响,这一直是瑜伽的主要应用。下一组影响涉及肌肉骨骼系统和疼痛(两者都与瑜伽的运动[体式]方面有关),以及心血管/内分泌(也与压力有关)和癌症。压力和精神健康、疼痛、糖尿病和癌症是现代医学中大多数情况下无法永久治愈的健康问题,尽管有缓解性治疗方法。这可能激发了人们对瑜伽等辅助方法的兴趣,以解决这些健康问题。研究时间表显示,瑜伽相关的研究在2000年代之后才得到了很大的扩展。2004年之后出现了明显的上升。如果我们只看临床试验或随机对照试验(rct)或系统评价,就会发现类似的趋势。在已发表的文献中,试验(临床和随机对照试验)的比例约为10- 15%,这与2000年代左右获得关注的其他领域(例如非侵入性脑刺激)相当。地理分布表明,37%的瑜伽相关研究成果来自美国,19%来自印度,13%来自欧洲,31%来自世界其他地区。因此,利益是广泛的和全球性的。至少,美国2000年后瑜伽相关研究的兴起可以归因于1998年至2005年间美国国立卫生研究院国家补充与综合健康中心(NCCIH)的资金大幅增加。我们只能推测,这一领域的研究在20世纪90年代末达到了一个临界质量,这为这一领域注入了更多的资金,产生了更多的研究,并创造了一个持续发展至今的正反馈循环。我们建议,为了维持甚至加速该领域未来的研究,除了进行更多的随机对照试验和临床试验(将试验的百分比从10-15%增加到20-25%)外,还必须提高严谨性和可重复性。该领域的研究成果必须以循证解决健康问题的方式惠及普通人。如果没有这一点,印度和美国等民主国家的加速资助将无法实现。
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引用次数: 0
Cortisol Responses to Psychosocial Stress: The Role of Childhood Maltreatment and Depression. 皮质醇对社会心理压力的反应:童年虐待和抑郁症的作用》(The Role of Childhood Maltreatment and Depression.
Uma Rao, Matthew C Morris

This study examined cortisol reactivity to repeated psychosocial stressors in 35 adolescents and young adults aged 12 to 26 years. Participants were divided into three study groups: controls with no history of major depressive disorder (MDD) or childhood maltreatment (n = 18); a diagnosis of MDD at Time 1 but no history of maltreatment (MDD-only; n = 10); and both MDD and maltreatment (MDD+MALTX; n = 7). Participants with MDD recovered from their depressive episode prior to the second psychosocial stress task. The MDD-only group had higher cortisol responses at Time 1 relative to other groups. No between-group differences were observed in cortisol responses at Time 2. Depressed individuals with maltreatment did not differ from controls in their cortisol responses at Time 1 or Time 2. Findings suggest that elevated cortisol stress reactivity is a state-dependent correlate of depression in youth with no history of maltreatment.

本研究调查了 35 名 12 至 26 岁的青少年和年轻人对重复性社会心理压力的皮质醇反应性。参与者被分为三个研究组:无重度抑郁症(MDD)或童年虐待史的对照组(n = 18);在时间 1 诊断为 MDD 但无虐待史的对照组(仅 MDD;n = 10);同时患有 MDD 和虐待史的对照组(MDD+MALTX;n = 7)。患有 MDD 的参与者在进行第二次心理压力任务前已从抑郁发作中恢复过来。与其他组别相比,仅患有 MDD 的组别在第一时间的皮质醇反应较高。在时间 2 的皮质醇反应中没有观察到组间差异。受到虐待的抑郁症患者在时间 1 或时间 2 的皮质醇反应与对照组没有差异。研究结果表明,皮质醇应激反应性升高是无虐待史青少年抑郁的状态依赖性相关因素。
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引用次数: 0
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International journal of public mental health and neurosciences
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