Oral health case reports最新文献

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Understanding the Importance of Gene and Environment in the Etiology and Prevention of Type 2 Diabetes Mellitus in High-Risk Populations. 了解基因和环境在高危人群 2 型糖尿病的病因和预防中的重要性。

Oral health case reports

Pub Date : 2016-03-01 Epub Date: 2016-03-14

Marsha Samsom, Tushar Trivedi, Olubunmi Orekoya, Shraddha Vyas

Current literature focuses on the complications and treatment of Type 2 Diabetes Mellitus (T2DM) while clustering environmental and genetic factors to explain the disease. Interventions proposed to reduce diabetes prevalence should focus predominantly on initiating active rapports of family members and promoting a more communication-oriented preventative approach between diabetics and non-diabetics. Due to varying risks in T2DM by race and ethnicity, these populations should follow race-appropriate guidelines to prevent further T2DM occurrence and complications. The review consists of information related to the genetic component of T2DM to help identify high-risk groups and focuses on the environmental aspect of the disease to help consider appropriate techniques to reduce disease burden. Genetic factors play important roles in the pathogenesis of diabetes and thus are an essential element of understanding the cause of the disease and possible methods of prevention. Focusing on high-risk groups with T2DM could have profound effects on the current health care situation. In this review, we discuss the epidemiology of diabetes in the United States and propose methods of preventing and delaying the development of T2DM in high-risk individuals.

目前的文献主要关注 2 型糖尿病（T2DM）的并发症和治疗，同时将环境和遗传因素集中在一起来解释这种疾病。为降低糖尿病发病率而提出的干预措施应主要侧重于启动家庭成员之间的积极关系，并促进糖尿病患者与非糖尿病患者之间以沟通为导向的预防方法。由于不同种族和民族患 T2DM 的风险不同，这些人群应遵循与种族相适应的指南，以预防 T2DM 的进一步发生和并发症。本综述包括与 T2DM 遗传因素有关的信息，以帮助确定高危人群，并侧重于该疾病的环境因素，以帮助考虑采用适当的技术来减轻疾病负担。遗传因素在糖尿病的发病机制中起着重要作用，因此是了解糖尿病病因和可能的预防方法的基本要素。关注 T2DM 高危人群会对当前的医疗状况产生深远影响。在这篇综述中，我们讨论了美国的糖尿病流行病学，并提出了预防和延缓高危人群患 T2DM 的方法。

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引用次数: 0

Understanding the Importance of Gene and Environment in the Etiology and Prevention of Type 2 Diabetes Mellitus in High-Risk Populations 了解基因和环境在高危人群2型糖尿病发病及预防中的重要性

Oral health case reports

Pub Date : 2016-03-01 DOI: 10.4172/2471-8726.1000112

Marsha Samsom, Tushar Trivedi, O. Orekoya, Shraddha Vyas

目前的文献主要集中在2型糖尿病(T2DM)的并发症和治疗上，并将环境和遗传因素聚类来解释该疾病。提出的减少糖尿病患病率的干预措施应主要侧重于发起积极的家庭成员关系，并促进糖尿病患者和非糖尿病患者之间更注重沟通的预防方法。由于不同种族和民族的T2DM风险不同，这些人群应遵循适合种族的指南，以防止进一步发生T2DM和并发症。该综述包括与2型糖尿病遗传成分相关的信息，以帮助确定高危人群，并侧重于疾病的环境方面，以帮助考虑适当的技术来减轻疾病负担。遗传因素在糖尿病的发病机制中起着重要的作用，因此是了解疾病原因和可能的预防方法的重要因素。关注2型糖尿病高危人群可能对当前的卫生保健状况产生深远影响。在这篇综述中，我们讨论了美国糖尿病的流行病学，并提出了预防和延缓高危人群发展为2型糖尿病的方法。

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引用次数: 14

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